Endothelial cell tetrahydrobiopterin deficiency attenuates LPS-induced vascular dysfunction and hypotension

Vascular Pharmacology

Volumn 77, Issue , 2016, Pages 69-79

  Chuaiphichai, Surawee ^a,b   Starr, Anna ^c   Nandi, Manasi ^c   Channon, Keith M ^a,b   McNeill, Eileen ^a,b,c  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

Endothelial cell; Hypotension; LPS; Tetrahydrobiopterin; Vascular dysfunction

Indexed keywords

LIPOPOLYSACCHARIDE; NITRIC OXIDE; PHENYLEPHRINE; TETRAHYDROBIOPTERIN; BIOPTERIN; GCH1 PROTEIN, MOUSE; GUANOSINE TRIPHOSPHATE CYCLOHYDROLASE I; SAPROPTERIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOSYNTHESIS; ENDOTHELIUM CELL; EX VIVO STUDY; GCH1 GENE; GENE; HYPOTENSION; MESENTERIC ARTERY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEFICIENCY; UPREGULATION; VASCULAR DISEASE; VASCULAR DYSFUNCTION; VASCULAR RING; VASOCONSTRICTION; VASODILATATION; ANALOGS AND DERIVATIVES; ANIMAL; ANTAGONISTS AND INHIBITORS; BLOOD; C57BL MOUSE; ENDOTOXEMIA; ENZYMOLOGY; GENETICS; HEMODYNAMICS; MALE; METABOLISM; PATHOPHYSIOLOGY; PHENYLKETONURIA; PHYSIOLOGY; TRANSGENIC MOUSE; VASCULAR ENDOTHELIUM;

ANIMALS; BIOPTERIN; ENDOTHELIUM, VASCULAR; ENDOTOXEMIA; GTP CYCLOHYDROLASE; HEMODYNAMICS; HYPOTENSION; LIPOPOLYSACCHARIDES; MALE; MICE, INBRED C57BL; MICE, TRANSGENIC; NITRIC OXIDE; PHENYLKETONURIAS; VASODILATION;

EID: 84958037849     PISSN: 15371891     EISSN: 18793649     Source Type: Journal    
DOI: 10.1016/j.vph.2015.08.009     Document Type: Article

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