Pdgfrβ+ mural preadipocytes contribute to adipocyte hyperplasia induced by high-fat-diet feeding and prolonged cold exposure in adult mice

Cell Metabolism

Volumn 23, Issue 2, 2016, Pages 350-359

  Vishvanath, Lavanya ^a   Macpherson, Karen A ^a   Hepler, Chelsea ^a   Wang, Qiong A ^a   Shao, Mengle ^a   Spurgin, Stephen B ^a   Wang, Margaret Y ^a   Kusminski, Christine M ^a   Morley, Thomas S ^a   Gupta, Rana K ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD34 ANTIGEN; CELL SURFACE MARKER; GREEN FLUORESCENT PROTEIN; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA 2; PLATELET DERIVED GROWTH FACTOR BETA RECEPTOR; STEM CELL ANTIGEN 1; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN; ZINC FINGER PROTEIN 423; BIOLOGICAL MARKER; DNA BINDING PROTEIN; EBFAZ PROTEIN, MOUSE; TRANSCRIPTION FACTOR;

ADIPOGENESIS; ADIPOSE DERIVED STEM CELL; ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL HYPERPLASIA; CELL INFILTRATION; CELL LINEAGE; CELL POPULATION; CELL PROLIFERATION; CELL TRANSDIFFERENTIATION; COLD EXPOSURE; COLONY FORMING UNIT; CONTROLLED STUDY; DIET INDUCED OBESITY; EXTRACELLULAR MATRIX; LIPID DIET; MALE; MESENCHYMAL STEM CELL; MOUSE; NONHUMAN; PERICYTE; PRIORITY JOURNAL; PROADIPOCYTE; TRANSACTIVATION; WHITE ADIPOCYTE; WHITE ADIPOSE TISSUE; ADIPOCYTE; AGING; ANIMAL; BROWN ADIPOSE TISSUE; C57BL MOUSE; CELL COUNT; CELL MEMBRANE; COLD; FEEDING BEHAVIOR; FEMALE; HYPERPLASIA; INFLAMMATION; METABOLISM; PATHOLOGY; STEM CELL; TRANSGENIC MOUSE;

ADIPOCYTES; ADIPOGENESIS; ADIPOSE TISSUE, BROWN; ADIPOSE TISSUE, WHITE; AGING; ANIMALS; BIOMARKERS; CELL COUNT; CELL LINEAGE; CELL MEMBRANE; COLD TEMPERATURE; DIET, HIGH-FAT; DNA-BINDING PROTEINS; FEEDING BEHAVIOR; FEMALE; HYPERPLASIA; INFLAMMATION; MALE; MICE, INBRED C57BL; MICE, TRANSGENIC; RECEPTOR, PLATELET-DERIVED GROWTH FACTOR BETA; STEM CELLS; TRANSCRIPTION FACTORS;

EID: 84957952804     PISSN: 15504131     EISSN: 19327420     Source Type: Journal    
DOI: 10.1016/j.cmet.2015.10.018     Document Type: Article

References (30)

1. A. Armulik, G. Genové, and C. Betsholtz Pericytes: developmental, physiological, and pathological perspectives, problems, and promises Dev. Cell 21 2011 193 215
2. R. Berry, and M.S. Rodeheffer Characterization of the adipocyte cellular lineage in vivo Nat. Cell Biol. 15 2013 302 308
3. R. Berry, E. Jeffery, and M.S. Rodeheffer Weighing in on adipocyte precursors Cell Metab. 19 2014 8 20
4. W.P. Cawthorn, E.L. Scheller, and O.A. MacDougald Adipose tissue stem cells meet preadipocyte commitment: going back to the future J. Lipid Res. 53 2012 227 246
5. Y.Y. Chau, R. Bandiera, A. Serrels, O.M. Martínez-Estrada, W. Qing, M. Lee, J. Slight, A. Thornburn, R. Berry, S. McHaffie, and et al. Visceral and subcutaneous fat have different origins and evidence supports a mesothelial source Nat. Cell Biol. 16 2014 367 375
6. R.K. Gupta, Z. Arany, P. Seale, R.J. Mepani, L. Ye, H.M. Conroe, Y.A. Roby, H. Kulaga, R.R. Reed, and B.M. Spiegelman Transcriptional control of preadipocyte determination by Zfp423 Nature 464 2010 619 623
7. R.K. Gupta, R.J. Mepani, S. Kleiner, J.C. Lo, M.J. Khandekar, P. Cohen, A. Frontini, D.C. Bhowmick, L. Ye, S. Cinti, and B.M. Spiegelman Zfp423 expression identifies committed preadipocytes and localizes to adipose endothelial and perivascular cells Cell Metab. 15 2012 230 239
8. A. Hammarstedt, S. Hedjazifar, L. Jenndahl, S. Gogg, J. Grünberg, B. Gustafson, E. Klimcakova, V. Stich, D. Langin, M. Laakso, and U. Smith WISP2 regulates preadipocyte commitment and PPARγ activation by BMP4 Proc. Natl. Acad. Sci. USA 110 2013 2563 2568
9. J. Himms-Hagen, A. Melnyk, M.C. Zingaretti, E. Ceresi, G. Barbatelli, and S. Cinti Multilocular fat cells in WAT of CL-316243-treated rats derive directly from white adipocytes Am. J. Physiol. Cell Physiol. 279 2000 C670 C681
10. C.S. Hudak, O. Gulyaeva, Y. Wang, S.M. Park, L. Lee, C. Kang, and H.S. Sul Pref-1 marks very early mesenchymal precursors required for adipose tissue development and expansion Cell Rep. 8 2014 678 687
11. D. Jansson, J. Rustenhoven, S. Feng, D. Hurley, R.L. Oldfield, P.S. Bergin, E.W. Mee, R.L. Faull, and M. Dragunow A role for human brain pericytes in neuroinflammation J. Neuroinflammation 11 2014 104
12. E. Jeffery, C.D. Church, B. Holtrup, L. Colman, and M.S. Rodeheffer Rapid depot-specific activation of adipocyte precursor cells at the onset of obesity Nat. Cell Biol. 17 2015 376 385
13. Y. Jiang, D.C. Berry, W. Tang, and J.M. Graff Independent stem cell lineages regulate adipose organogenesis and adipose homeostasis Cell Rep. 9 2014 1007 1022
14. A.W. Joe, L. Yi, Y. Even, A.W. Vogl, and F.M. Rossi Depot-specific differences in adipogenic progenitor abundance and proliferative response to high-fat diet Stem Cells 27 2009 2563 2570
15. S. Kajimura, B.M. Spiegelman, and P. Seale Brown and Beige Fat: Physiological Roles beyond Heat Generation Cell Metab. 22 2015 546 559
16. Y.H. Lee, A.P. Petkova, E.P. Mottillo, and J.G. Granneman In vivo identification of bipotential adipocyte progenitors recruited by β3-adrenoceptor activation and high-fat feeding Cell Metab. 15 2012 480 491
17. Y.H. Lee, A.P. Petkova, A.A. Konkar, and J.G. Granneman Cellular origins of cold-induced brown adipocytes in adult mice FASEB J. 29 2015 286 299
18. J.Z. Long, K.J. Svensson, L. Tsai, X. Zeng, H.C. Roh, X. Kong, R.R. Rao, J. Lou, I. Lokurkar, W. Baur, and et al. A smooth muscle-like origin for beige adipocytes Cell Metab. 19 2014 810 820
19. Y. Macotela, B. Emanuelli, M.A. Mori, S. Gesta, T.J. Schulz, Y.H. Tseng, and C.R. Kahn Intrinsic differences in adipocyte precursor cells from different white fat depots Diabetes 61 2012 1691 1699
20. M.E. McDonald, C. Li, H. Bian, B.D. Smith, M.D. Layne, and S.R. Farmer Myocardin-related transcription factor A regulates conversion of progenitors to beige adipocytes Cell 160 2015 105 118
21. M. Rosenwald, A. Perdikari, T. Rülicke, and C. Wolfrum Bi-directional interconversion of brite and white adipocytes Nat. Cell Biol. 15 2013 659 667
22. M. Rydén, M. Uzunel, J.L. Hård, E. Borgström, J.E. Mold, E. Arner, N. Mejhert, D.P. Andersson, Y. Widlund, M. Hassan, and et al. Transplanted Bone Marrow-Derived Cells Contribute to Human Adipogenesis Cell Metab. 22 2015 408 417
23. J. Sanchez-Gurmaches, and D.A. Guertin Adipocytes arise from multiple lineages that are heterogeneously and dynamically distributed Nat. Commun. 5 2014 4099
24. P. Seale, B. Bjork, W. Yang, S. Kajimura, S. Chin, S. Kuang, A. Scimè, S. Devarakonda, H.M. Conroe, H. Erdjument-Bromage, and et al. PRDM16 controls a brown fat/skeletal muscle switch Nature 454 2008 961 967
25. K. Stark, A. Eckart, S. Haidari, A. Tirniceriu, M. Lorenz, M.L. von Brühl, F. Gärtner, A.G. Khandoga, K.R. Legate, R. Pless, and et al. Capillary and arteriolar pericytes attract innate leukocytes exiting through venules and 'instruct' them with pattern-recognition and motility programs Nat. Immunol. 14 2013 41 51
26. K. Sun, C.M. Kusminski, and P.E. Scherer Adipose tissue remodeling and obesity J. Clin. Invest. 121 2011 2094 2101
27. K.V. Tran, O. Gealekman, A. Frontini, M.C. Zingaretti, M. Morroni, A. Giordano, A. Smorlesi, J. Perugini, R. De Matteis, A. Sbarbati, and et al. The vascular endothelium of the adipose tissue gives rise to both white and brown fat cells Cell Metab. 15 2012 222 229
28. Q.A. Wang, C. Tao, R.K. Gupta, and P.E. Scherer Tracking adipogenesis during white adipose tissue development, expansion and regeneration Nat. Med. 19 2013 1338 1344
29. W. Wang, M. Kissig, S. Rajakumari, L. Huang, H.W. Lim, K.J. Won, and P. Seale Ebf2 is a selective marker of brown and beige adipogenic precursor cells Proc. Natl. Acad. Sci. USA 111 2014 14466 14471
30. J. Wu, P. Boström, L.M. Sparks, L. Ye, J.H. Choi, A.H. Giang, M. Khandekar, K.A. Virtanen, P. Nuutila, G. Schaart, and et al. Beige adipocytes are a distinct type of thermogenic fat cell in mouse and human Cell 150 2012 366 376