Pref-1 marks very early mesenchymal precursors required for adipose tissue development and expansion

Cell Reports

Volumn 8, Issue 3, 2014, Pages 678-687

  Hudak, Carolyn S ^a   Gulyaeva, Olga ^b   Wang, Yuhui ^a   Park, Seung min ^b,c,d   Lee, Luke ^c   Kang, Chulho ^b   Sul, Hei Sook ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c University of California at Berkeley   (United States)

^d STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD24 ANTIGEN; CD45 ANTIGEN; CELL PROTEIN; DIPHTHERIA TOXIN; DIPHTHERIA TOXIN A; FAT DROPLET; FATTY ACID SYNTHASE; KI 67 ANTIGEN; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PREADIPOCYTE FACTOR 1; PROTEIN ZFP423; TRANSCRIPTION FACTOR SOX9; UNCLASSIFIED DRUG; WNT10A PROTEIN; ZINC FINGER PROTEIN; DLK1 PROTEIN, MOUSE; DNA BINDING PROTEIN; EBFAZ PROTEIN, MOUSE; SIGNAL PEPTIDE; TRANSCRIPTION FACTOR;

ADIPOCYTE; ADIPOGENESIS; ADIPOSE DERIVED STEM CELL; ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOLOGICAL MODEL; BROWN ADIPOSE TISSUE; CELL PROLIFERATION; CELL STRUCTURE; COMPARATIVE STUDY; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; FAS GENE; FLUORESCENCE ACTIVATED CELL SORTING; FLUORESCENCE ANALYSIS; INTRAABDOMINAL FAT; LIPID DIET; MESENCHYME CELL; MOLECULAR DYNAMICS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TISSUE EXPANSION; TRANSGENIC MOUSE; WHITE ADIPOSE TISSUE; ANIMAL; CELL CULTURE; CYTOLOGY; EMBRYOLOGY; EMBRYONIC STEM CELL; GENETICS; MESODERM; METABOLISM; WHITE ADIPOCYTE;

MUS MUSCULUS;

ADIPOCYTES, WHITE; ADIPOGENESIS; ADIPOSE TISSUE, WHITE; ANIMALS; CELLS, CULTURED; DNA-BINDING PROTEINS; EMBRYONIC STEM CELLS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MESODERM; MICE; PPAR GAMMA; TRANSCRIPTION FACTORS;

EID: 84923309352     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2014.06.060     Document Type: Article

References (24)

1. Berry, R., and Rodeheffer, M.S. (2013). Characterization of the adipocyte cellular lineage in vivo. Nat. Cell Biol. 15, 302-308.
2. Billon, N., and Dani, C. (2012). Developmental origins of the adipocyte lineage: new insights from genetics and genomics studies. Stem Cell Rev. 8, 55-66.
3. Cawthorn, W.P., Bree, A.J., Yao, Y., Du, B., Hemati, N., Martinez-Santibañez, G., and MacDougald, O.A. (2012). Wnt6, Wnt10a and Wnt10b inhibit adipogenesis and stimulate osteoblastogenesis through a β-catenin-dependent mechanism. Bone 50, 477-489.
4. Dimov, I.K., Lu, R., Lee, E.P., Seita, J., Sahoo, D., Park, S.M., Weissman, I.L., and Lee, L.P. (2014). Discriminating cellular heterogeneity using microwellbased RNA cytometry. Nat. Commun. 5, 3451.
5. Farmer, S.R. (2006). Transcriptional control of adipocyte formation. Cell Metab. 4, 263-273.
6. Gimble, J.M., Bunnell, B.A., and Floyd, Z.E. (2011). Prospecting for adipose progenitor cell biomarkers: biopanning for gold with in vivo phage display. Cell Stem Cell 9, 1-2.
7. Gregoire, F.M., Smas, C.M., and Sul, H.S. (1998). Understanding adipocyte differentiation. Physiol. Rev. 78, 783-809.
8. Gupta, R.K., Mepani, R.J., Kleiner, S., Lo, J.C., Khandekar, M.J., Cohen, P., Frontini, A., Bhowmick, D.C., Ye, L., Cinti, S., and Spiegelman, B.M. (2012). Zfp423 expression identifies committed preadipocytes and localizes to adipose endothelial and perivascular cells. Cell Metab. 15, 230-239.
9. Hudak, C.S., and Sul, H.S. (2013). Pref-1, a gatekeeper of adipogenesis. Front. Endocrinol. (Lausanne) 4, 79.
10. Kanda, T., Sullivan, K.F., and Wahl, G.M. (1998). Histone-GFP fusion protein enables sensitive analysis of chromosome dynamics in living mammalian cells. Curr. Biol. 8, 377-385.
11. Lee, K., Villena, J.A., Moon, Y.S., Kim, K.-H., Lee, S., Kang, C., and Sul, H.S. (2003). Inhibition of adipogenesis and development of glucose intolerance by soluble preadipocyte factor-1 (Pref-1). J. Clin. Invest. 111, 453-461.
12. MacDougald, O.A., and Burant, C.F. (2005). Fickle factor foils fat fate. Nat. Cell Biol. 7, 543-545.
13. Mohsen-Kanson, T., Hafner, A.-L., Wdziekonski, B., Villageois, P., Chignon-Sicard, B., and Dani, C. (2013). Expression of cell surface markers during selfrenewal and differentiation of human adipose-derived stem cells. Biochem. Biophys. Res. Commun. 430, 871-875.
14. Moitra, J., Mason, M.M., Olive, M., Krylov, D., Gavrilova, O., Marcus-Samuels, B., Feigenbaum, L., Lee, E., Aoyama, T., Eckhaus, M., et al. (1998). Life without white fat: a transgenic mouse. Genes Dev. 12, 3168-3181.
15. Nir, T., Melton, D.A., and Dor, Y. (2007). Recovery from diabetes in mice by beta cell regeneration. J. Clin. Invest. 117, 2553-2561.
16. Olson, L.E., and Soriano, P. (2011). PDGFRb signaling regulates mural cell plasticity and inhibits fat development. Dev. Cell 20, 815-826.
17. Perl, A.K., Wert, S.E., Nagy, A., Lobe, C.G., and Whitsett, J.A. (2002). Early restriction of peripheral and proximal cell lineages during formation of the lung. Proc. Natl. Acad. Sci. USA 99, 10482-10487.
18. Rodeheffer, M.S., Birsoy, K., and Friedman, J.M. (2008). Identification of white adipocyte progenitor cells in vivo. Cell 135, 240-249.
19. Smas, C.M., and Sul, H.S. (1993). Pref-1, a protein containing EGF-like repeats, inhibits adipocyte differentiation. Cell 73, 725-734.
20. Smas, C.M., Chen, L., and Sul, H.S. (1997). Cleavage of membrane-associated pref-1 generates a soluble inhibitor of adipocyte differentiation. Mol. Cell. Biol. 17, 977-988.
21. Tang, Q.Q., and Lane, M.D. (2012). Adipogenesis: from stem cell to adipocyte. Annu. Rev. Biochem. 81, 715-736.
22. Tang, W., Zeve, D., Suh, J.M., Bosnakovski, D., Kyba, M., Hammer, R.E., Tallquist, M.D., and Graff, J.M. (2008). White fat progenitor cells reside in the adipose vasculature. Science 322, 583-586.
23. Wang, Y., and Sul, H.S. (2009). Pref-1 regulates mesenchymal cell commitment and differentiation through Sox9. Cell Metab. 9, 287-302.
24. Wang, Y., Zhao, L., Smas, C., and Sul, H.S. (2010). Pref-1 interacts with fibronectin to inhibit adipocyte differentiation. Mol. Cell. Biol. 30, 3480-3492.