Rapamycin prevents bronchiolitis obliterans through increasing infiltration of regulatory B cells in a murine tracheal transplantation model Read at the 95th Annual Meeting of the American Association for Thoracic Surgery, Seattle, Washington, April 25-29, 2015.

Journal of Thoracic and Cardiovascular Surgery

Volumn 151, Issue 2, 2016, Pages 487-496.e3

  Zhao, Yunge ^a   Gillen, Jacob R ^a   Meher, Akshaya K ^a   Burns, Jordan A ^a   Kron, Irving L ^a   Lau, Christine L ^a  

^a UNIVERSITY OF VIRGINIA   (United States)

Author keywords

Bronchiolitis obliterans; FoxP3 regulatory T cells; Mouse heterotopic tracheal transplant; Rapamycin; Regulatory B lymphocytes

Indexed keywords

DIMETHYL SULFOXIDE; EOSIN; HEMATOXYLIN; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; INTERLEUKIN 10; INTERLEUKIN 13; INTERLEUKIN 17; INTERLEUKIN 6; RAPAMYCIN; TRANSFORMING GROWTH FACTOR BETA1; ANTIINFLAMMATORY AGENT; AUTACOID; CYTOKINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ASSAY; B LYMPHOCYTE; BRONCHIOLITIS OBLITERANS; CELL INFILTRATION; CONFERENCE PAPER; CONTROLLED STUDY; CYTOKINE RELEASE; IMMUNOCOMPETENT CELL; IMMUNOHISTOCHEMISTRY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; STAINING; STANDARD; TRACHEA SURGERY; TRANSPLANTATION; ANIMAL; BAGG ALBINO MOUSE; C57BL MOUSE; DISEASE MODEL; DRUG EFFECTS; IMMUNOLOGY; METABOLISM; NEUTROPHIL CHEMOTAXIS; PATHOLOGY; PHENOTYPE; REGULATORY T LYMPHOCYTE; TIME FACTOR; TRACHEA;

ANIMALS; ANTI-INFLAMMATORY AGENTS; B-LYMPHOCYTES; BRONCHIOLITIS OBLITERANS; CHEMOTAXIS, LEUKOCYTE; CYTOKINES; DISEASE MODELS, ANIMAL; INFLAMMATION MEDIATORS; MALE; MICE, INBRED BALB C; MICE, INBRED C57BL; PHENOTYPE; SIROLIMUS; T-LYMPHOCYTES, REGULATORY; TIME FACTORS; TRACHEA;

EID: 84957690217     PISSN: 00225223     EISSN: 1097685X     Source Type: Journal    
DOI: 10.1016/j.jtcvs.2015.08.116     Document Type: Conference Paper

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