IgG subclass staining in routine renal biopsy material

American Journal of Surgical Pathology

Volumn 40, Issue 5, 2016, Pages 617-626

  Hemminger, Jessica ^a   Nadasdy, Gyongyi ^a   Satoskar, Anjali ^a   Brodsky, Sergey V ^a   Nadasdy, Tibor ^a  

^a THE OHIO STATE UNIVERSITY WEXNER MEDICAL CENTER   (United States)

Author keywords

IgG subclass dysproteinemias; IgG subclass glomerulonephritis; IgG subclass staining; IgG subclasses in kidney biopsies

Indexed keywords

BIOLOGICAL MARKER; IMMUNOGLOBULIN G; MONOCLONAL ANTIBODY;

BIOPSY; CLASSIFICATION; DIFFERENTIAL DIAGNOSIS; FLUORESCENT ANTIBODY TECHNIQUE; GLOMERULONEPHRITIS; HUMAN; IMMUNOLOGY; KIDNEY; PATHOLOGY; PREDICTIVE VALUE; RISK FACTOR;

ANTIBODIES, MONOCLONAL; BIOMARKERS; BIOPSY; DIAGNOSIS, DIFFERENTIAL; FLUORESCENT ANTIBODY TECHNIQUE; GLOMERULONEPHRITIS; HUMANS; IMMUNOGLOBULIN G; KIDNEY; PREDICTIVE VALUE OF TESTS; RISK FACTORS;

EID: 84957632878     PISSN: 01475185     EISSN: 15320979     Source Type: Journal    
DOI: 10.1097/PAS.0000000000000605     Document Type: Article

References (67)

1. Vidarsson G, Dekkers G, Rispens T. IgG subclasses and allotypes: from structure to effector functions. Front Immunol. 2014;5:520.
2. Hamilton RG. Human IgG subclass measurements in the clinical laboratory. Clin Chem. 1987;33:1707-1725.
3. Bannister KM, Howarth GS, Clarkson AR, et al. Glomerular IgG subclass distribution in human glomerulonephritis. Clin Nephrol. 1983;19:161-165.
4. Satoskar AA, Brodsky SV, Nadasdy G, et al. Discrepancies in glomerular and tubulointerstitial/vascular immune complex IgG subclasses in lupus nephritis. Lupus. 2011;20:1396-1403.
5. Huang CC, Lehman A, Albawardi A, et al. IgG subclass staining in renal biopsies with membranous glomerulonephritis indicates subclass switch during disease progression. Mod Pathol. 2013;26: 799-805.
6. Beck LH Jr., Bonegio RG, Lambeau G, et al. M-type phospholipase A2 receptor as target antigen in idiopathic membranous nephropathy. N Engl J Med. 2009;361:11-21.
7. Hofstra JM, Beck LH Jr., Beck DM, et al. Anti-phospholipase A(2) receptor antibodies correlate with clinical status in idiopathic membranous nephropathy. Clin J Am Soc Nephrol. 2011;6: 1286-1291.
8. Qin W, Beck LH Jr., Zeng C, et al. Anti-phospholipase A2 receptor antibody in membranous nephropathy. J Am Soc Nephrol. 2011;22: 1137-1143.
9. Murtas C, Bruschi M, Candiano G, et al. Coexistence of different circulating anti-podocyte antibodies in membranous nephropathy. Clin J Am Soc Nephrol. 2012;7:1394-1400.
10. Tomas NM, Beck LH Jr., Meyer-Schwesinger C, et al. Thrombospondin type-1 domain-containing 7 A in idiopathic membranous nephropathy. N Engl J Med. 2014;371:2277-2287.
11. Haas M. IgG subclass deposits in glomeruli of lupus and nonlupus membranous nephropathies. Am J Kidney Dis. 1994;23:358-364.
12. Kuroki A, Shibata T, Honda H, et al. Glomerular and serum IgG subclasses in diffuse proliferative lupus nephritis, membranous lupus nephritis, and idiopathic membranous nephropathy. Intern Med. 2002;41:936-942.
13. Ohtani H, Wakui H, Komatsuda A, et al. Distribution of glomerular IgG subclass deposits in malignancy-associated membranous nephropathy. Nephrol Dial Transplant. 2004;19:574-579.
14. Imai H, Hamai K, Komatsuda A, et al. IgG subclasses in patients with membranoproliferative glomerulonephritis, membranous nephropathy, and lupus nephritis. Kidney Int. 1997;51:270-276.
15. Qu Z, Liu G, Li J, et al. Absence of glomerular IgG4 deposition in patients with membranous nephropathy may indicate malignancy. Nephrol Dial Transplant. 2012;27:1931-1937.
16. Noel LH, Aucouturier P, Monteiro RC, et al. Glomerular and serum immunoglobulin G subclasses in membranous nephropathy and anti-glomerular basement membrane nephritis. Clin Immunol Immunopathol. 1988;46:186-194.
17. Kearney N, Podolak J, Matsumura L, et al. Patterns of IgG subclass deposits in membranous glomerulonephritis in renal allografts. Transplant Proc. 2011;43:3743-3746.
18. Xie Q, Li Y, Xue J, et al. Renal phospholipase A2 receptor in hepatitis B virus-associated membranous nephropathy. Am J Nephrol. 2015;41:345-353.
19. Larsen CP, Messias NC, Silva FG, et al. Determination of primary versus secondary membranous glomerulopathy utilizing phospholipase A2 receptor staining in renal biopsies. Mod Pathol. 2013;26: 709-715.
20. Lonnbro-Widgren J, Ebefors K, Molne J, et al. Glomerular IgG subclasses in idiopathic and malignancy-associated membranous nephropathy. Clin Kidney J. 2015;8:433-439.
21. Markowitz GS. Membranous glomerulopathy: emphasis on secondary forms and disease variants. Adv Anat Pathol. 2001;8:119-125.
22. Glassock RJ. Secondary membranous glomerulonephritis. Nephrol Dial Transplant. 1992;7(suppl 1):64-71.
23. Song YS, Min KW, Kim JH, et al. Differential diagnosis of lupus and primary membranous nephropathies by IgG subclass analysis. Clin J Am Soc Nephrol. 2012;7:1947-1955.
24. Zuniga R, Markowitz GS, Arkachaisri T, et al. Identification of IgG subclasses and C-reactive protein in lupus nephritis: the relationship between the composition of immune deposits and FCgamma receptor type IIA alleles. Arthritis Rheum. 2003;48:460-470.
25. Rosenstock JL, Markowitz GS, Valeri AM, et al. Fibrillary and immunotactoid glomerulonephritis: distinct entities with different clinical and pathologic features. Kidney Int. 2003;63:1450-1461.
26. Bowman C, Ambrus K, Lockwood CM. Restriction of human IgG subclass expression in the population of auto-antibodies to glomerular basement membrane. Clin Exp Immunol. 1987;69: 341-349.
27. Weber M, Lohse AW, Manns M, et al. IgG subclass distribution of autoantibodies to glomerular basement membrane in Goodpasture's syndrome compared to other autoantibodies. Nephron. 1988;49: 54-57.
28. Qu Z, Cui Z, Liu G, et al. The distribution of IgG subclass deposition on renal tissues from patients with anti-glomerular basement membrane disease. BMC Immunol. 2013;14:19.
29. Coley SM, Shirazian S, Radhakrishnan J, et al. Monoclonal IgG1kappa anti-glomerular basement membrane disease: a case report. Am J Kidney Dis. 2015;65:322-326.
30. Kambham N, Markowitz GS, Appel GB, et al. Heavy chain deposition disease: the disease spectrum. Am J Kidney Dis. 1999;33: 954-962.
31. Hjelholt A, Christiansen G, Sorensen US, et al. IgG subclass profiles in normal human sera of antibodies specific to five kinds of microbial antigens. Pathog Dis. 2013;67:206-213.
32. Cream JJ, Howard A, Virella G. IgG heavy chain sub-classes in mixed cryoglobulins. Immunology. 1972;23:405-411.
33. Musset L, Duarte F, Gaillard O, et al. Immunochemical characterization of monoclonal IgG containing mixed cryoglobulins. Clin Immunol Immunopathol. 1994;70:166-170.
34. Mondelli MU, Zorzoli I, Cerino A, et al. Clonality and specificity of cryoglobulins associated with HCV: pathophysiological implications. J Hepatol. 1998;29:879-886.
35. Conley ME, Cooper MD, Michael AF. Selective deposition of immunoglobulin A1 in immunoglobulin A nephropathy, anaphylactoid purpura nephritis, and systemic lupus erythematosus. J Clin Invest. 1980;66:1432-1436.
36. Baskin B, Pettersson E, Rekola S, et al. Studies of the molecular basis of IgA production, subclass regulation and class-switch recombination in IgA nephropathy patients. Clin Exp Immunol. 1996;106:509-517.
37. Zhang C, Zeng X, Li Z, et al. Immunoglobulin A nephropathy: current progress and future directions. Transl Res. 2015;166: 134-144.
38. Wada Y, Ogata H, Takeshige Y, et al. Clinical significance of IgG deposition in the glomerular mesangial area in patients with IgA nephropathy. Clin Exp Nephrol. 2013;17:73-82.
39. Bellur SS, Troyanov S, Cook HT, et al. Immunostaining findings in IgA nephropathy: correlation with histology and clinical outcome in the Oxford classification patient cohort. Nephrol Dial Transplant. 2011;26:2533-2536.
40. Nieuwhof C, Kruytzer M, Frederiks P, et al. Chronicity index and mesangial IgG deposition are risk factors for hypertension and renal failure in early IgA nephropathy. Am J Kidney Dis. 1998;31: 962-970.
41. Nasri H. IgG deposition in IgA nephropathy patients. J Renal Inj Prev. 2013;2:11-13.
42. Baradaran AR. IgG deposition in IgA nephropathy patients. J Renal Inj Prev. 2013;2:39-40.
43. Nasri H, Sajjadieh S, Mardani S, et al. Correlation of immunostaining findings with demographic data and variables of Oxford classification in IgA nephropathy. J Nephropathol. 2013;2:190-195.
44. Suzuki H, Fan R, Zhang Z, et al. Aberrantly glycosylated IgA1 in IgA nephropathy patients is recognized by IgG antibodies with restricted heterogeneity. J Clin Invest. 2009;119:1668-1677.
45. Suzuki H, Moldoveanu Z, Hall S, et al. IgA nephropathy: characterization of IgG antibodies specific for galactose-deficient IgA1. Contrib Nephrol. 2007;157:129-133.
46. Novak J, Tomana M, Matousovic K, et al. IgA1-containing immune complexes in IgA nephropathy differentially affect proliferation of mesangial cells. Kidney Int. 2005;67:504-513.
47. Nasr SH, Markowitz GS, Stokes MB, et al. Proliferative glomerulonephritis with monoclonal IgG deposits: a distinct entity mimicking immune-complex glomerulonephritis. Kidney Int. 2004;65:85-96.
48. Nasr SH, Satoskar A, Markowitz GS, et al. Proliferative glomerulonephritis with monoclonal IgG deposits. J Am Soc Nephrol. 2009;20:2055-2064.
49. Albawardi A, Satoskar A, Von Visger J, et al. Proliferative glomerulonephritis with monoclonal IgG deposits recurs or may develop de novo in kidney allografts. Am J Kid Dis. 2011;58: 276-281.
50. Nasr SH, Sethi S, Cornell LD, et al. Proliferative glomerulonephritis with monoclonal IgG deposits recurs in the allograft. Clin J Am Soc Nephrol. 2011;6:122-132.
51. Iskandar SS, Falk RJ, Jennette JC. Clinical and pathologic features of fibrillary glomerulonephritis. Kidney Int. 1992;42:1401-1407.
52. Alpers CE, Kowalewska J. Fibrillary glomerulonephritis and immunotactoid glomerulopathy. J Am Soc Nephrol. 2008;19:34-37.
53. Bridoux F, Hugue V, Coldefy O, et al. Fibrillary glomerulonephritis and immunotactoid (microtubular) glomerulopathy are associated with distinct immunologic features. Kidney Int. 2002;62:1764-1775.
54. Javaugue V, Karras A, Glowacki F, et al. Long-term kidney disease outcomes in fibrillary glomerulonephritis: a case series of 27 patients. Am J Kidney Dis. 2013;62:679-690.
55. Nasr SH, Valeri AM, Cornell LD, et al. Fibrillary glomerulonephritis: a report of 66 cases from a single institution. Clin J Am Soc Nephrol. 2011;6:775-784.
56. Nasr SH, Fidler ME, Cornell LD, et al. Immunotactoid glomerulopathy: clinicopathologic and proteomic study. Nephrol Dial Transplant. 2012;27:4137-4146.
57. Hemminger J, Kandarpa M, Tsai A, et al. Proliferative glomerulonephritis with monoclonal IgG1 kappa deposits in a hepatitis C virus positive patient. Am J Kidney Dis. 2015;pii:S0272-6386(15)01319-0. doi: 10.1053/j.ajkd.2015.08.032. [Epub ahead of print].
58. Oe Y, Soma J, Sato H, et al. Heavy chain deposition disease: an overview. Clin Exp Nephrol. 2013;17:771-778.
59. Nasr SH, Said SM, Valeri AM, et al. The diagnosis and characteristics of renal heavy-chain and heavy/light-chain amyloidosis and their comparison with renal light-chain amyloidosis. Kidney Int. 2013;83:463-470.
60. Mai HL, Sheikh-Hamad D, Herrera GA, et al. Immunoglobulin heavy chain can be amyloidogenic: morphologic characterization including immunoelectron microscopy. Am J Surg Pathol. 2003;27: 541-545.
61. Said SM, Sethi S, Valeri AM, et al. Renal amyloidosis: origin and clinicopathologic correlations of 474 recent cases. Clin J Am Soc Nephrol. 2013;8:1515-1523.
62. Picken MM, Herrera GA. The burden of "sticky" amyloid: typing challenges. Arch Pathol Lab Med. 2007;131:850-851.
63. Satoskar AA, Burdge K, Cowden DJ, et al. Typing of amyloidosis in renal biopsies: diagnostic pitfalls. Arch Pathol Lab Med. 2007;131:917-922.
64. Yamaguchi Y, Kanetsuna Y, Honda K, et al. Characteristic tubulointerstitial nephritis in IgG4-related disease. Human Pathol. 2012;43:536-549.
65. Saeki T, Kawano M. IgG4-related kidney disease. Kidney Int. 2014; 85:251-257.
66. Kawano M, Saeki T. IgG4-related kidney disease-an update. Curr Opin Nephrol Hypertens. 2015;24:193-201.
67. Alexander MP, Larsen CP, Gibson IW, et al. Membranous glomerulonephritis is a manifestation of IgG4-related disease. Kidney Int. 2013;83:455-462.