Renal Phospholipase A2 Receptor in Hepatitis B Virus-Associated Membranous Nephropathy

American Journal of Nephrology

Volumn 41, Issue 4-5, 2015, Pages 345-353

  Xie, Qionghong ^a   Li, Yan ^a   Xue, Jun ^a   Xiong, Zuquan ^a   Wang, Liang ^b   Sun, Zhuxing ^b   Ren, Yueheng ^a   Zhu, Xiaoye ^a   Hao, Chuan Ming ^a  

^a FUDAN UNIVERSITY   (China)

^b WUXI PEOPLE S HOSPITAL AFFILIATED TO NANJING MEDICAL UNIVERSITY   (China)

Author keywords

HBV associated membranous nephropathy; Membranous nephropathy; Phospholipase A2 receptor

Indexed keywords

ANTIBODY; COMPLEMENT COMPONENT C1Q; HEPATITIS B CORE ANTIGEN; HEPATITIS B SURFACE ANTIGEN; PHOSPHOLIPASE A2 RECEPTOR; PHOSPHOLIPASE A2 RECEPTOR ANTIBODY; SERUM ALBUMIN; UNCLASSIFIED DRUG; AUTOANTIBODY;

ARTICLE; DISEASE SEVERITY; ELECTRON MICROSCOPY; ENZYME BLOOD LEVEL; FEMALE; FOCAL GLOMERULOSCLEROSIS; GLOMERULONEPHRITIS; HEPATITIS B VIRUS; HUMAN; HUMAN CELL; HUMAN TISSUE; IDIOPATHIC DISEASE; IMMUNOFLUORESCENCE; IMMUNOGLOBULIN A NEPHROPATHY; KIDNEY BIOPSY; LUPUS ERYTHEMATOSUS NEPHRITIS; MAJOR CLINICAL STUDY; MALE; MEMBRANOUS GLOMERULONEPHRITIS; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN URINE LEVEL; RETROSPECTIVE STUDY; THORAX RADIOGRAPHY; CASE CONTROL STUDY; COMPLICATION; GLOMERULONEPHRITIS, MEMBRANOPROLIFERATIVE; GLOMERULONEPHRITIS, MEMBRANOUS; GLOMERULUS; HEK293 CELL LINE; HEPATITIS B; IMMUNOLOGY; KIDNEY; METABOLISM; SEVERITY OF ILLNESS INDEX;

AUTOANTIBODIES; CASE-CONTROL STUDIES; FEMALE; GLOMERULONEPHRITIS, MEMBRANOPROLIFERATIVE; GLOMERULONEPHRITIS, MEMBRANOUS; HEK293 CELLS; HEPATITIS B SURFACE ANTIGENS; HEPATITIS B, CHRONIC; HUMANS; KIDNEY; KIDNEY GLOMERULUS; LUPUS NEPHRITIS; MALE; RECEPTORS, PHOSPHOLIPASE A2; RETROSPECTIVE STUDIES; SEVERITY OF ILLNESS INDEX;

EID: 84931843673     PISSN: 02508095     EISSN: 14219670     Source Type: Journal    
DOI: 10.1159/000431331     Document Type: Article

References (23)

1. Beck LH Jr, et al: M-type phospholipase A2 receptor as target antigen in idiopathic membranous nephropathy. N Engl J Med 2009; 361: 11-21.
2. Liu YH, et al: Association of phospholipase A2 receptor 1 polymorphisms with idiopathic membranous nephropathy in Chinese patients in Taiwan. J Biomed Sci 2010; 17: 81.
3. Stahl R, Hoxha E, Fechner K: PLA2R autoantibodies and recurrent membranous nephropathy after transplantation. N Engl J Med 2010; 363: 496-498.
4. Knehtl M, et al: A case of phospholipase A 2 receptor-positive membranous nephropathy preceding sarcoid-associated granulomatous tubulointerstitial nephritis. Am J Kidney Dis 2011; 57: 140-143.
5. Hofstra JM, et al: Anti-phospholipase A 2 receptor antibodies correlate with clinical status in idiopathic membranous nephropathy. Clin J Am Soc Nephrol 2011; 6: 1286-1291.
6. Qin W, et al: Anti-phospholipase A2 receptor antibody in membranous nephropathy. J Am Soc Nephrol 2011; 22: 1137-1143.
7. Quintana LF, et al: Antiphospholipase A2 receptor antibody levels predict the risk of posttransplantation recurrence of membranous nephropathy. Transplantation 2015, Epub ahead of print.
8. Hoxha E, et al: An immunofluorescence test for phospholipase-A 2-receptor antibodies and its clinical usefulness in patients with membranous glomerulonephritis. Nephrol Dial Transplant 2011; 26: 2526-2532.
9. Kanigicherla D, et al: Anti-PLA2R antibodies measured by ELISA predict long-term outcome in a prevalent population of patients with idiopathic membranous nephropathy. Kidney Int 2013; 83: 940-948.
10. Akiyama S, et al: Prevalence of anti-phospholipase A2 receptor antibodies in Japanese patients with membranous nephropathy. Clin Exp Nephrol 2014, Epub ahead of print.
11. Hoxha E, et al: Enhanced expression of the M-type phospholipase A2 receptor in glomeruli correlates with serum receptor antibodies in primary membranous nephropathy. Kidney Int 2012; 82: 797-804.
12. Debiec H, Ronco P: PLA2R autoantibodies and PLA2R glomerular deposits in membranous nephropathy. N Engl J Med 2011; 364: 689-690.
13. Stanescu HC, et al: Risk HLA-DQA1 and PLA(2)R1 alleles in idiopathic membranous nephropathy. N Engl J Med 2011; 364: 616-626.
14. Lv J, et al: Interaction between PLA2R1 and HLA-DQA1 variants associates with anti-PLA2R antibodies and membranous nephropathy. J Am Soc Nephrol 2013; 24: 1323-1329.
15. Larsen CP, et al: Determination of primary versus secondary membranous glomerulopathy utilizing phospholipase A2 receptor staining in renal biopsies. Mod Pathol 2013; 26: 709-715.
16. Lai CL, et al: Viral hepatitis B. Lancet 2003; 362: 2089-2094.
17. Liu J, Fan D: Hepatitis B in China. Lancet 2007; 369: 1582-1583.
18. Levy M, Chen N: Worldwide perspective of hepatitis B-associated glomerulonephritis in the 80s. Kidney Int Suppl 1991; 35:S24-S33.
19. Levy M, Kleinknecht C: Membranous glomerulonephritis and hepatitis B virus infection. Nephron 1980; 26: 259-265.
20. Editorial committee of Chinese Journal of Internal Medicine: A summary of the discussion meeting of hepatitis B virus(HBV)-associated glomerulonephritis. Chinese J Int Med 1990; 29: 519-521.
21. Svobodova B, et al: Kidney biopsy is a sensitive tool for retrospective diagnosis of PLA2Rrelated membranous nephropathy. Nephrol Dial Transplant 2013; 28: 1839-1844.
22. Bhimma R, Coovadia HM: Hepatitis B virusassociated nephropathy. Am J Nephrol 2004; 24: 198-211.
23. Takekoshi Y, et al: Strong association between membranous nephropathy and hepatitis-B surface antigenaemia in Japanese children. Lancet 1978; 2: 1065-1068.