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Volumn 10, Issue 1, 2016, Pages 57-71

Asthma and chronic obstructive pulmonary disease overlap: Asthmatic chronic obstructive pulmonary disease or chronic obstructive asthma?

Author keywords

asthma chronic obstructive pulmonary disease overlap syndrome; phenotype

Indexed keywords

BETA ADRENERGIC RECEPTOR STIMULATING AGENT; BIOLOGICAL MARKER; BRONCHODILATING AGENT; CHEMOKINE RECEPTOR CXCR2 ANTAGONIST; CORTICOSTEROID; INTERLEUKIN 1 ANTIBODY; INTERLEUKIN 13 ANTIBODY; INTERLEUKIN 17 ANTIBODY; INTERLEUKIN 5 ANTIBODY; MACROLIDE; MITOGEN ACTIVATED PROTEIN KINASE P38 INHIBITOR; MUSCARINIC RECEPTOR BLOCKING AGENT; PHOSPHODIESTERASE IV INHIBITOR; PLACEBO; TIOTROPIUM BROMIDE;

EID: 84957549467     PISSN: 17534658     EISSN: 17534666     Source Type: Journal    
DOI: 10.1177/1753465815617082     Document Type: Review
Times cited : (28)

References (102)
  • 1
    • 75649102186 scopus 로고    scopus 로고
    • Targeted treatment in COPD: A multi-system approach for a multi-system disease
    • Anderson D., Macnee W., (2009) Targeted treatment in COPD: a multi-system approach for a multi-system disease. Int J Chron Obstruct Pulmon Dis 4: 321-335.
    • (2009) Int J Chron Obstruct Pulmon Dis , vol.4 , pp. 321-335
    • Anderson, D.1    MacNee, W.2
  • 2
    • 0036724894 scopus 로고    scopus 로고
    • Smoking and lung function of Lung Health Study participants after 11 years
    • Anthonisen N., Connett J., Murray R., (2002) Smoking and lung function of Lung Health Study participants after 11 years. Am J Respir Crit Care Med 166: 675-679.
    • (2002) Am J Respir Crit Care Med , vol.166 , pp. 675-679
    • Anthonisen, N.1    Connett, J.2    Murray, R.3
  • 3
    • 80052936263 scopus 로고    scopus 로고
    • Acute exacerbations of chronic obstructive pulmonary disease: Identification of biologic clusters and their biomarkers
    • Bafadhel M., McKenna S., Terry S., Mistry V., Reid C., Haldar P., et al. (2011) Acute exacerbations of chronic obstructive pulmonary disease: identification of biologic clusters and their biomarkers. Am J Respir Crit Care Med 184: 662-671.
    • (2011) Am J Respir Crit Care Med , vol.184 , pp. 662-671
    • Bafadhel, M.1    McKenna, S.2    Terry, S.3    Mistry, V.4    Reid, C.5    Haldar, P.6
  • 4
    • 84941028441 scopus 로고    scopus 로고
    • Therapeutic approaches to asthma-chronic obstructive pulmonary disease overlap syndromes
    • Barnes P., (2015) Therapeutic approaches to asthma-chronic obstructive pulmonary disease overlap syndromes. J Allergy Clin Immunol 136: 531-545.
    • (2015) J Allergy Clin Immunol , vol.136 , pp. 531-545
    • Barnes, P.1
  • 5
    • 33745896155 scopus 로고    scopus 로고
    • Recent advances in the relationship between obesity, inflammation, and insulin resistance
    • Bastard J., Maachi M., Lagathu C., Kim M., Caron M., Vidal H., et al. (2006) Recent advances in the relationship between obesity, inflammation, and insulin resistance. Eur Cytokine Netw 17: 4-12.
    • (2006) Eur Cytokine Netw , vol.17 , pp. 4-12
    • Bastard, J.1    Maachi, M.2    Lagathu, C.3    Kim, M.4    Caron, M.5    Vidal, H.6
  • 6
    • 0034748035 scopus 로고    scopus 로고
    • Increased sputum IL-8 and IL-5 in asymptomatic nonspecific airway hyperresponsiveness
    • Betz R., Kohlhaufl M., Kassner G., Mullinger B., Maier K., Brand P., et al. (2001) Increased sputum IL-8 and IL-5 in asymptomatic nonspecific airway hyperresponsiveness. Lung 179: 119-133.
    • (2001) Lung , vol.179 , pp. 119-133
    • Betz, R.1    Kohlhaufl, M.2    Kassner, G.3    Mullinger, B.4    Maier, K.5    Brand, P.6
  • 7
    • 0024996333 scopus 로고
    • Small airway dimensions in smokers with obstruction to airflow
    • Bosken C., Wiggs B., Pare P., Hogg J., (1990) Small airway dimensions in smokers with obstruction to airflow. Am Rev Respir Dis 142: 563-570.
    • (1990) Am Rev Respir Dis , vol.142 , pp. 563-570
    • Bosken, C.1    Wiggs, B.2    Pare, P.3    Hogg, J.4
  • 8
    • 33645131645 scopus 로고    scopus 로고
    • Smoking and asthma: Clinical and radiologic features, lung function, and airway inflammation
    • Boulet L., Lemiere C., Archambault F., Carrier G., Descary M., Deschesnes F., (2006) Smoking and asthma: clinical and radiologic features, lung function, and airway inflammation. Chest 129: 661-668.
    • (2006) Chest , vol.129 , pp. 661-668
    • Boulet, L.1    Lemiere, C.2    Archambault, F.3    Carrier, G.4    Descary, M.5    Deschesnes, F.6
  • 9
    • 0038651182 scopus 로고    scopus 로고
    • Airway inflammation in asthma with incomplete reversibility of airflow obstruction
    • Boulet L., Turcotte H., Turcot O., Chakir J., (2003) Airway inflammation in asthma with incomplete reversibility of airflow obstruction. Respir Med 97: 739-744.
    • (2003) Respir Med , vol.97 , pp. 739-744
    • Boulet, L.1    Turcotte, H.2    Turcot, O.3    Chakir, J.4
  • 10
    • 20144382091 scopus 로고    scopus 로고
    • Sputum eosinophilia and the short term response to inhaled mometasone in chronic obstructive pulmonary disease
    • Brightling C., McKenna S., Hargadon B., Birring S., Green R., Siva R., et al. (2005) Sputum eosinophilia and the short term response to inhaled mometasone in chronic obstructive pulmonary disease. Thorax 60: 193-198.
    • (2005) Thorax , vol.60 , pp. 193-198
    • Brightling, C.1    McKenna, S.2    Hargadon, B.3    Birring, S.4    Green, R.5    Siva, R.6
  • 11
    • 0034727453 scopus 로고    scopus 로고
    • Sputum eosinophilia and short-term response to prednisolone in chronic obstructive pulmonary disease: A randomised controlled trial
    • Brightling C., Monteiro W., Ward R., Parker D., Morgan M., Wardlaw A., et al. (2000) Sputum eosinophilia and short-term response to prednisolone in chronic obstructive pulmonary disease: a randomised controlled trial. Lancet 356: 1480-1485.
    • (2000) Lancet , vol.356 , pp. 1480-1485
    • Brightling, C.1    Monteiro, W.2    Ward, R.3    Parker, D.4    Morgan, M.5    Wardlaw, A.6
  • 12
    • 33747074082 scopus 로고    scopus 로고
    • Bronchial hyperresponsiveness and the development of asthma and COPD in asymptomatic individuals: SAPALDIA cohort study
    • Brutsche M., Downs S., Schindler C., Gerbase M., Schwartz J., Frey M., et al. (2006) Bronchial hyperresponsiveness and the development of asthma and COPD in asymptomatic individuals: SAPALDIA cohort study. Thorax 61: 671-677.
    • (2006) Thorax , vol.61 , pp. 671-677
    • Brutsche, M.1    Downs, S.2    Schindler, C.3    Gerbase, M.4    Schwartz, J.5    Frey, M.6
  • 13
    • 3543146737 scopus 로고    scopus 로고
    • Parameters associated with persistent airflow obstruction in chronic severe asthma
    • Bumbacea D., Campbell D., Nguyen L., Carr D., Barnes P., Robinson D., et al. (2004) Parameters associated with persistent airflow obstruction in chronic severe asthma. Eur Respir J 24: 122-128.
    • (2004) Eur Respir J , vol.24 , pp. 122-128
    • Bumbacea, D.1    Campbell, D.2    Nguyen, L.3    Carr, D.4    Barnes, P.5    Robinson, D.6
  • 14
    • 0034643610 scopus 로고    scopus 로고
    • Randomised, double blind, placebo controlled study of fluticasone propionate in patients with moderate to severe chronic obstructive pulmonary disease: The ISOLDE trial
    • Burge P., Calverley P., Jones P., Spencer S., Anderson J., Maslen T., (2000) Randomised, double blind, placebo controlled study of fluticasone propionate in patients with moderate to severe chronic obstructive pulmonary disease: the ISOLDE trial. BMJ 320: 1297-1303.
    • (2000) BMJ , vol.320 , pp. 1297-1303
    • Burge, P.1    Calverley, P.2    Jones, P.3    Spencer, S.4    Anderson, J.5    Maslen, T.6
  • 16
    • 84926647762 scopus 로고    scopus 로고
    • Asthma-COPD overlap. Clinical relevance of genomic signatures of type 2 inflammation in chronic obstructive pulmonary disease
    • Christenson S., Steiling K., van den Berge M., Hijazi K., Hiemstra P., Postma D., et al. (2015) Asthma-COPD overlap. Clinical relevance of genomic signatures of type 2 inflammation in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 191: 758-766.
    • (2015) Am J Respir Crit Care Med , vol.191 , pp. 758-766
    • Christenson, S.1    Steiling, K.2    Van Den Berge, M.3    Hijazi, K.4    Hiemstra, P.5    Postma, D.6
  • 18
    • 77950297480 scopus 로고    scopus 로고
    • Fixed airflow obstruction due to asthma or chronic obstructive pulmonary disease: 5-year follow-up
    • Contoli M., Baraldo S., Marku B., Casolari P., Marwick J., Turato G., et al. (2010) Fixed airflow obstruction due to asthma or chronic obstructive pulmonary disease: 5-year follow-up. J Allergy Clin Immunol 125: 830-837.
    • (2010) J Allergy Clin Immunol , vol.125 , pp. 830-837
    • Contoli, M.1    Baraldo, S.2    Marku, B.3    Casolari, P.4    Marwick, J.5    Turato, G.6
  • 20
    • 1842587885 scopus 로고    scopus 로고
    • C-reactive protein and other circulating markers of inflammation in the prediction of coronary heart disease
    • Danesh J., Wheeler J., Hirschfield G., Eda S., Eiriksdottir G., Rumley A., et al. (2004) C-reactive protein and other circulating markers of inflammation in the prediction of coronary heart disease. N Engl J Med 350: 1387-1397.
    • (2004) N Engl J Med , vol.350 , pp. 1387-1397
    • Danesh, J.1    Wheeler, J.2    Hirschfield, G.3    Eda, S.4    Eiriksdottir, G.5    Rumley, A.6
  • 21
    • 0033533144 scopus 로고    scopus 로고
    • Oral corticosteroids in patients admitted to hospital with exacerbations of chronic obstructive pulmonary disease: A prospective randomised controlled trial
    • Davies L., Angus R., Calverley P., (1999) Oral corticosteroids in patients admitted to hospital with exacerbations of chronic obstructive pulmonary disease: a prospective randomised controlled trial. Lancet 354: 456-460.
    • (1999) Lancet , vol.354 , pp. 456-460
    • Davies, L.1    Angus, R.2    Calverley, P.3
  • 22
    • 33846248798 scopus 로고    scopus 로고
    • Incidence of chronic obstructive pulmonary disease in a cohort of young adults according to the presence of chronic cough and phlegm
    • De Marco R., Accordini S., Cerveri I., Corsico A., Anto J., Kunzli N., et al. (2007) Incidence of chronic obstructive pulmonary disease in a cohort of young adults according to the presence of chronic cough and phlegm. Am J Respir Crit Care Med 175: 32-39.
    • (2007) Am J Respir Crit Care Med , vol.175 , pp. 32-39
    • De Marco, R.1    Accordini, S.2    Cerveri, I.3    Corsico, A.4    Anto, J.5    Kunzli, N.6
  • 23
    • 84877605913 scopus 로고    scopus 로고
    • The coexistence of asthma and chronic obstructive pulmonary disease (COPD): Prevalence and risk factors in young, middle-aged and elderly people from the general population
    • De Marco R., Pesce G., Marcon A., Accordini S., Antonicelli L., Bugiani M., et al. (2013) The coexistence of asthma and chronic obstructive pulmonary disease (COPD): prevalence and risk factors in young, middle-aged and elderly people from the general population. PLoS One 8: e62985.
    • (2013) PLoS One , vol.8 , pp. e62985
    • De Marco, R.1    Pesce, G.2    Marcon, A.3    Accordini, S.4    Antonicelli, L.5    Bugiani, M.6
  • 24
    • 16344376370 scopus 로고    scopus 로고
    • Inflamm-ageing and lifelong antigenic load as major determinants of ageing rate and longevity
    • De Martinis M., Franceschi C., Monti D., Ginaldi L., (2005) Inflamm-ageing and lifelong antigenic load as major determinants of ageing rate and longevity. FEBS Lett 579: 2035-2039.
    • (2005) FEBS Lett , vol.579 , pp. 2035-2039
    • De Martinis, M.1    Franceschi, C.2    Monti, D.3    Ginaldi, L.4
  • 25
    • 83155164527 scopus 로고    scopus 로고
    • Asthma, chronic obstructive pulmonary disease, and mortality in the U.S. Population
    • Diaz-Guzman E., Khosravi M., Mannino D., (2011) Asthma, chronic obstructive pulmonary disease, and mortality in the U.S. population. COPD 8: 400-407.
    • (2011) COPD , vol.8 , pp. 400-407
    • Diaz-Guzman, E.1    Khosravi, M.2    Mannino, D.3
  • 27
    • 84877784528 scopus 로고    scopus 로고
    • Which patients with chronic obstructive pulmonary disease benefit from the addition of an inhaled corticosteroid to their bronchodilator? A cluster analysis
    • Disantostefano R., Li H., Rubin D., Stempel D., (2013) Which patients with chronic obstructive pulmonary disease benefit from the addition of an inhaled corticosteroid to their bronchodilator? A cluster analysis. BMJ Open 3: e001838.
    • (2013) BMJ Open , vol.3 , pp. e001838
    • Disantostefano, R.1    Li, H.2    Rubin, D.3    Stempel, D.4
  • 29
    • 0037320195 scopus 로고    scopus 로고
    • Differences in airway inflammation in patients with fixed airflow obstruction due to asthma or chronic obstructive pulmonary disease
    • Fabbri L., Romagnoli M., Corbetta L., Casoni G., Busljetic K., Turato G., et al. (2003) Differences in airway inflammation in patients with fixed airflow obstruction due to asthma or chronic obstructive pulmonary disease. Am J Respir Crit Care Med 167: 418-424.
    • (2003) Am J Respir Crit Care Med , vol.167 , pp. 418-424
    • Fabbri, L.1    Romagnoli, M.2    Corbetta, L.3    Casoni, G.4    Busljetic, K.5    Turato, G.6
  • 30
    • 0017402583 scopus 로고
    • The natural history of chronic airflow obstruction
    • Fletcher C., Peto R., (1977) The natural history of chronic airflow obstruction. Br Med J 1: 1645-1648.
    • (1977) Br Med J , vol.1 , pp. 1645-1648
    • Fletcher, C.1    Peto, R.2
  • 31
    • 84903473961 scopus 로고    scopus 로고
    • Systemic Inflammation in older adults with asthma-COPD overlap syndrome
    • Fu J., McDonald V., Gibson P., Simpson J., (2014) Systemic Inflammation in older adults with asthma-COPD overlap syndrome. Allergy Asthma Immunol Res 6: 316-324.
    • (2014) Allergy Asthma Immunol Res , vol.6 , pp. 316-324
    • Fu, J.1    McDonald, V.2    Gibson, P.3    Simpson, J.4
  • 32
    • 84941075853 scopus 로고    scopus 로고
    • Understanding the pathophysiology of the asthma-chronic obstructive pulmonary disease overlap syndrome
    • Gelb A., Nadel J., (2015) Understanding the pathophysiology of the asthma-chronic obstructive pulmonary disease overlap syndrome. J Allergy Clin Immunol 136: 553-555.
    • (2015) J Allergy Clin Immunol , vol.136 , pp. 553-555
    • Gelb, A.1    Nadel, J.2
  • 33
    • 84920593779 scopus 로고    scopus 로고
    • Biological clustering supports both 'Dutch' and 'British' hypotheses of asthma and chronic obstructive pulmonary disease
    • Ghebre M., Bafadhel M., Desai D., Cohen S., Newbold P., Rapley L., et al. (2015) Biological clustering supports both 'Dutch' and 'British' hypotheses of asthma and chronic obstructive pulmonary disease. J Allergy Clin Immunol 135: 63-72.
    • (2015) J Allergy Clin Immunol , vol.135 , pp. 63-72
    • Ghebre, M.1    Bafadhel, M.2    Desai, D.3    Cohen, S.4    Newbold, P.5    Rapley, L.6
  • 34
    • 68049084752 scopus 로고    scopus 로고
    • The overlap syndrome of asthma and COPD: What are its features and how important is it?
    • Gibson P., Simpson J., (2009) The overlap syndrome of asthma and COPD: what are its features and how important is it? Thorax 64: 728-735.
    • (2009) Thorax , vol.64 , pp. 728-735
    • Gibson, P.1    Simpson, J.2
  • 36
    • 79251596862 scopus 로고    scopus 로고
    • Effects of inhaled corticosteroids in stable chronic obstructive pulmonary disease
    • Glaab T., Taube C., (2011) Effects of inhaled corticosteroids in stable chronic obstructive pulmonary disease. Pulm Pharmacol Ther 24: 15-22.
    • (2011) Pulm Pharmacol Ther , vol.24 , pp. 15-22
    • Glaab, T.1    Taube, C.2
  • 37
    • 73449086493 scopus 로고    scopus 로고
    • Global Initiative for Asthma (GINA). Available at: (accessed 12 August 2015)
    • Global Initiative for Asthma (GINA) (2015) Global strategy for asthma management and prevention. Available at: http://www.ginasthma.org/ (. accessed 12 August 2015).
    • (2015) Global Strategy for Asthma Management and Prevention
  • 39
    • 84904466626 scopus 로고    scopus 로고
    • Distribution of clinical phenotypes in patients with chronic obstructive pulmonary disease caused by biomass and tobacco smoke
    • Golpe R., Sanjuan L., Cano J., Castro A., Perez de Llano L., (2014) Distribution of clinical phenotypes in patients with chronic obstructive pulmonary disease caused by biomass and tobacco smoke. Arch Bronconeumol 50: 318-324.
    • (2014) Arch Bronconeumol , vol.50 , pp. 318-324
    • Golpe, R.1    Sanjuan, L.2    Cano, J.3    Castro, A.4    Perez De Llano, L.5
  • 40
    • 0037202790 scopus 로고    scopus 로고
    • Asthma exacerbations and sputum eosinophil counts: A randomised controlled trial
    • Green R., Brightling C., McKenna S., Hargadon B., Parker D., Bradding P., et al. (2002) Asthma exacerbations and sputum eosinophil counts: a randomised controlled trial. Lancet 360: 1715-1721.
    • (2002) Lancet , vol.360 , pp. 1715-1721
    • Green, R.1    Brightling, C.2    McKenna, S.3    Hargadon, B.4    Parker, D.5    Bradding, P.6
  • 41
    • 84905660075 scopus 로고    scopus 로고
    • The clinical and genetic features of COPD-asthma overlap syndrome
    • Hardin M., Cho M., McDonald M., Beaty T., Ramsdell J., Bhatt S., et al. (2014) The clinical and genetic features of COPD-asthma overlap syndrome. Eur Respir J 44: 341-350.
    • (2014) Eur Respir J , vol.44 , pp. 341-350
    • Hardin, M.1    Cho, M.2    McDonald, M.3    Beaty, T.4    Ramsdell, J.5    Bhatt, S.6
  • 43
    • 2942720573 scopus 로고    scopus 로고
    • The nature of small-airway obstruction in chronic obstructive pulmonary disease
    • Hogg J., Chu F., Utokaparch S., Woods R., Elliott W., Buzatu L., et al. (2004) The nature of small-airway obstruction in chronic obstructive pulmonary disease. N Engl J Med 350: 2645-2653.
    • (2004) N Engl J Med , vol.350 , pp. 2645-2653
    • Hogg, J.1    Chu, F.2    Utokaparch, S.3    Woods, R.4    Elliott, W.5    Buzatu, L.6
  • 44
    • 0033431650 scopus 로고    scopus 로고
    • Asthma attacks with eosinophilia predict mortality from chronic obstructive pulmonary disease in a general population sample
    • Hospers J., Schouten J., Weiss S., Rijcken B., Postma D., (1999) Asthma attacks with eosinophilia predict mortality from chronic obstructive pulmonary disease in a general population sample. Am J Respir Crit Care Med 160: 1869-1874.
    • (1999) Am J Respir Crit Care Med , vol.160 , pp. 1869-1874
    • Hospers, J.1    Schouten, J.2    Weiss, S.3    Rijcken, B.4    Postma, D.5
  • 45
    • 84893489901 scopus 로고    scopus 로고
    • Differences in plasma and sputum biomarkers between COPD and COPD-asthma overlap
    • Iwamoto H., Gao J., Koskela J., Kinnula V., Kobayashi H., Laitinen T., et al. (2014) Differences in plasma and sputum biomarkers between COPD and COPD-asthma overlap. Eur Respir J 43: 421-429.
    • (2014) Eur Respir J , vol.43 , pp. 421-429
    • Iwamoto, H.1    Gao, J.2    Koskela, J.3    Kinnula, V.4    Kobayashi, H.5    Laitinen, T.6
  • 47
    • 12144249965 scopus 로고    scopus 로고
    • Decline in lung function in the Busselton Health Study: The effects of asthma and cigarette smoking
    • James A., Palmer L., Kicic E., Maxwell P., Lagan S., Ryan G., et al. (2005) Decline in lung function in the Busselton Health Study: the effects of asthma and cigarette smoking. Am J Respir Crit Care Med 171: 109-114.
    • (2005) Am J Respir Crit Care Med , vol.171 , pp. 109-114
    • James, A.1    Palmer, L.2    Kicic, E.3    Maxwell, P.4    Lagan, S.5    Ryan, G.6
  • 48
    • 34447572685 scopus 로고    scopus 로고
    • Clinical relevance of airway remodelling in airway diseases
    • James A., Wenzel S., (2007) Clinical relevance of airway remodelling in airway diseases. Eur Respir J 30: 134-155.
    • (2007) Eur Respir J , vol.30 , pp. 134-155
    • James, A.1    Wenzel, S.2
  • 49
    • 77951979898 scopus 로고    scopus 로고
    • Induction of neutrophil gelatinase-associated lipocalin expression by co-stimulation with interleukin-17 and tumor necrosis factor-alpha is controlled by IkappaB-zeta but neither by C/EBP-beta nor C/EBP-delta
    • Karlsen J., Borregaard N., Cowland J., (2010) Induction of neutrophil gelatinase-associated lipocalin expression by co-stimulation with interleukin-17 and tumor necrosis factor-alpha is controlled by IkappaB-zeta but neither by C/EBP-beta nor C/EBP-delta. J Biol Chem 285: 14088-14100.
    • (2010) J Biol Chem , vol.285 , pp. 14088-14100
    • Karlsen, J.1    Borregaard, N.2    Cowland, J.3
  • 51
    • 0027194120 scopus 로고
    • Airways hyperresponsiveness, bronchodilator response, allergy and smoking predict improvement in FEV1 during long-term inhaled corticosteroid treatment. Dutch CNSLD Study Group
    • Kerstjens H., Overbeek S., Schouten J., Brand P., Postma D., (1993) Airways hyperresponsiveness, bronchodilator response, allergy and smoking predict improvement in FEV1 during long-term inhaled corticosteroid treatment. Dutch CNSLD Study Group. Eur Respir J 6: 868-876.
    • (1993) Eur Respir J , vol.6 , pp. 868-876
    • Kerstjens, H.1    Overbeek, S.2    Schouten, J.3    Brand, P.4    Postma, D.5
  • 52
    • 84860314088 scopus 로고    scopus 로고
    • Sputum eosinophilia can predict responsiveness to inhaled corticosteroid treatment in patients with overlap syndrome of COPD and asthma
    • Kitaguchi Y., Komatsu Y., Fujimoto K., Hanaoka M., Kubo K., (2012) Sputum eosinophilia can predict responsiveness to inhaled corticosteroid treatment in patients with overlap syndrome of COPD and asthma. Int J Chron Obstruct Pulmon Dis 7: 283-289.
    • (2012) Int J Chron Obstruct Pulmon Dis , vol.7 , pp. 283-289
    • Kitaguchi, Y.1    Komatsu, Y.2    Fujimoto, K.3    Hanaoka, M.4    Kubo, K.5
  • 53
    • 70350509638 scopus 로고    scopus 로고
    • Eosinophil viability is increased by acidic pH in a cAMP- and GPR65-dependent manner
    • Kottyan L., Collier A., Cao K., Niese K., Hedgebeth M., Radu C., et al. (2009) Eosinophil viability is increased by acidic pH in a cAMP- and GPR65-dependent manner. Blood 114: 2774-2782.
    • (2009) Blood , vol.114 , pp. 2774-2782
    • Kottyan, L.1    Collier, A.2    Cao, K.3    Niese, K.4    Hedgebeth, M.5    Radu, C.6
  • 54
    • 0032558685 scopus 로고    scopus 로고
    • A 15-year follow-up study of ventilatory function in adults with asthma
    • Lange P., Parner J., Vestbo J., Schnohr P., Jensen G., (1998) A 15-year follow-up study of ventilatory function in adults with asthma. N Engl J Med 339: 1194-1200.
    • (1998) N Engl J Med , vol.339 , pp. 1194-1200
    • Lange, P.1    Parner, J.2    Vestbo, J.3    Schnohr, P.4    Jensen, G.5
  • 56
    • 6644229440 scopus 로고    scopus 로고
    • Effects of an interleukin-5 blocking monoclonal antibody on eosinophils, airway hyper-responsiveness, and the late asthmatic response
    • Leckie M., ten Brinke A., Khan J., Diamant Z., O'Connor B., Walls C., et al. (2000) Effects of an interleukin-5 blocking monoclonal antibody on eosinophils, airway hyper-responsiveness, and the late asthmatic response. Lancet 356: 2144-2148.
    • (2000) Lancet , vol.356 , pp. 2144-2148
    • Leckie, M.1    Ten Brinke, A.2    Khan, J.3    Diamant, Z.4    O'Connor, B.5    Walls, C.6
  • 57
    • 84903126427 scopus 로고    scopus 로고
    • Clinical characteristics of asthma combined with COPD feature
    • Lee H., Kang J., Yoon H., Lee S., Kwon S., Kim Y., et al. (2014) Clinical characteristics of asthma combined with COPD feature. Yonsei Med J 55: 980-986.
    • (2014) Yonsei Med J , vol.55 , pp. 980-986
    • Lee, H.1    Kang, J.2    Yoon, H.3    Lee, S.4    Kwon, S.5    Kim, Y.6
  • 59
    • 84874926231 scopus 로고    scopus 로고
    • The asthma-chronic obstructive pulmonary disease overlap syndrome: Pharmacotherapeutic considerations
    • Louie S., Zeki A., Schivo M., Chan A., Yoneda K., Avdalovic M., et al. (2013) The asthma-chronic obstructive pulmonary disease overlap syndrome: pharmacotherapeutic considerations. Expert Rev Clin Pharmacol 6: 197-219.
    • (2013) Expert Rev Clin Pharmacol , vol.6 , pp. 197-219
    • Louie, S.1    Zeki, A.2    Schivo, M.3    Chan, A.4    Yoneda, K.5    Avdalovic, M.6
  • 62
    • 84879411561 scopus 로고    scopus 로고
    • Multidimensional assessment and tailored interventions for COPD: Respiratory utopia or common sense?
    • McDonald V., Higgins I., Wood L., Gibson P., (2013) Multidimensional assessment and tailored interventions for COPD: respiratory utopia or common sense? Thorax 68: 691-694.
    • (2013) Thorax , vol.68 , pp. 691-694
    • McDonald, V.1    Higgins, I.2    Wood, L.3    Gibson, P.4
  • 63
    • 84862833566 scopus 로고    scopus 로고
    • Small-airway obstruction and emphysema in chronic obstructive pulmonary disease
    • McDonough J., Yuan R., Suzuki M., Seyednejad N., Elliott W., Sanchez P., et al. (2011) Small-airway obstruction and emphysema in chronic obstructive pulmonary disease. N Engl J Med 365: 1567-1575.
    • (2011) N Engl J Med , vol.365 , pp. 1567-1575
    • McDonough, J.1    Yuan, R.2    Suzuki, M.3    Seyednejad, N.4    Elliott, W.5    Sanchez, P.6
  • 64
    • 84893689291 scopus 로고    scopus 로고
    • Increased risk of exacerbation and hospitalization in subjects with an overlap phenotype: COPD-asthma
    • Menezes A., Montes de, Oca M., Perez-Padilla R., Nadeau G., Wehrmeister F., Lopez-Varela M., et al. (2014) Increased risk of exacerbation and hospitalization in subjects with an overlap phenotype: COPD-asthma. Chest 145: 297-304.
    • (2014) Chest , vol.145 , pp. 297-304
    • Menezes, A.1    Montes, D.2    Oca, M.3    Perez-Padilla, R.4    Nadeau, G.5    Wehrmeister, F.6    Lopez-Varela, M.7
  • 65
    • 79957999396 scopus 로고    scopus 로고
    • Arguments in favor of inhaled corticosteroids in COPD by phenotype instead of by severity
    • Miravitlles M., (2011) Arguments in favor of inhaled corticosteroids in COPD by phenotype instead of by severity. Arch Bronconeumol 47: 271-273.
    • (2011) Arch Bronconeumol , vol.47 , pp. 271-273
    • Miravitlles, M.1
  • 66
    • 84908144502 scopus 로고    scopus 로고
    • Generic utilities in chronic obstructive pulmonary disease patients stratified according to different staging systems
    • Miravitlles M., Huerta A., Fernandez-Villar J., Alcazar B., Villa G., Forne C., et al. (2014a) Generic utilities in chronic obstructive pulmonary disease patients stratified according to different staging systems. Health Qual Life Outcomes 12: 120.
    • (2014) Health Qual Life Outcomes , vol.12 , pp. 120
    • Miravitlles, M.1    Huerta, A.2    Fernandez-Villar, J.3    Alcazar, B.4    Villa, G.5    Forne, C.6
  • 68
    • 84878927718 scopus 로고    scopus 로고
    • Characterisation of the overlap COPD-asthma phenotype. Focus on physical activity and health status
    • Miravitlles M., Soriano J., Ancochea J., Munoz L., Duran-Tauleria E., Sanchez G., et al. (2013) Characterisation of the overlap COPD-asthma phenotype. Focus on physical activity and health status. Respir Med 107: 1053-1060.
    • (2013) Respir Med , vol.107 , pp. 1053-1060
    • Miravitlles, M.1    Soriano, J.2    Ancochea, J.3    Munoz, L.4    Duran-Tauleria, E.5    Sanchez, G.6
  • 69
    • 84880994463 scopus 로고    scopus 로고
    • Asthma, chronic obstructive pulmonary disease (COPD), and the overlap syndrome
    • Nakawah M., Hawkins C., Barbandi F., (2013) Asthma, chronic obstructive pulmonary disease (COPD), and the overlap syndrome. J Am Board Fam Med 26: 470-477.
    • (2013) J Am Board Fam Med , vol.26 , pp. 470-477
    • Nakawah, M.1    Hawkins, C.2    Barbandi, F.3
  • 70
    • 36049036539 scopus 로고    scopus 로고
    • Canadian Thoracic Society recommendations for management of chronic obstructive pulmonary disease - 2007 update
    • O'Donnell D., Aaron S., Bourbeau J., Hernandez P., Marciniuk D., Balter M., et al. (2007) Canadian Thoracic Society recommendations for management of chronic obstructive pulmonary disease-2007 update. Can Respir J 14 (Suppl. B): 5B-32B.
    • (2007) Can Respir J , vol.14 , pp. 5B-32B
    • O'Donnell, D.1    Aaron, S.2    Bourbeau, J.3    Hernandez, P.4    Marciniuk, D.5    Balter, M.6
  • 71
    • 0002770296 scopus 로고
    • The host factor in bronchitis
    • Orie N. G. M., Sluiter HJ, (eds). Assen, The Netherlands: Royal Van Gorcum
    • Orie N. G. M., Sluiter H. J., De Vries K., Tammeling G. J., Witkop J., (1961) The host factor in bronchitis. In: Orie N. G. M., Sluiter HJ, (eds) Bronchitis. Assen, The Netherlands: Royal Van Gorcum, 1961. pp. 43-59.
    • (1961) Bronchitis , vol.1961 , pp. 43-59
    • Orie, N.G.M.1    Sluiter, H.J.2    De Vries, K.3    Tammeling, G.J.4    Witkop, J.5
  • 72
    • 0032515756 scopus 로고    scopus 로고
    • Multicentre randomised placebo-controlled trial of inhaled fluticasone propionate in patients with chronic obstructive pulmonary disease. International COPD Study Group
    • Paggiaro P., Dahle R., Bakran I., Frith L., Hollingworth K., Efthimiou J., (1998) Multicentre randomised placebo-controlled trial of inhaled fluticasone propionate in patients with chronic obstructive pulmonary disease. International COPD Study Group. Lancet 351: 773-780.
    • (1998) Lancet , vol.351 , pp. 773-780
    • Paggiaro, P.1    Dahle, R.2    Bakran, I.3    Frith, L.4    Hollingworth, K.5    Efthimiou, J.6
  • 73
    • 33750618847 scopus 로고    scopus 로고
    • Mortality and airflow obstruction in asthma: A 17-year follow-up study
    • Panizza J., James A., Ryan G., de Klerk N., Finucane K., (2006) Mortality and airflow obstruction in asthma: a 17-year follow-up study. Intern Med J 36: 773-780.
    • (2006) Intern Med J , vol.36 , pp. 773-780
    • Panizza, J.1    James, A.2    Ryan, G.3    De Klerk, N.4    Finucane, K.5
  • 74
    • 0033711405 scopus 로고    scopus 로고
    • Partial reversibility of airflow limitation and increased exhaled NO and sputum eosinophilia in chronic obstructive pulmonary disease
    • Papi A., Romagnoli M., Baraldo S., Braccioni F., Guzzinati I., Saetta M., et al. (2000) Partial reversibility of airflow limitation and increased exhaled NO and sputum eosinophilia in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 162: 1773-1777.
    • (2000) Am J Respir Crit Care Med , vol.162 , pp. 1773-1777
    • Papi, A.1    Romagnoli, M.2    Baraldo, S.3    Braccioni, F.4    Guzzinati, I.5    Saetta, M.6
  • 75
    • 0023143612 scopus 로고
    • Rate of decline of lung function in subjects with asthma
    • Peat J., Woolcock A., Cullen K., (1987) Rate of decline of lung function in subjects with asthma. Eur J Respir Dis 70: 171-179.
    • (1987) Eur J Respir Dis , vol.70 , pp. 171-179
    • Peat, J.1    Woolcock, A.2    Cullen, K.3
  • 76
    • 84871958002 scopus 로고    scopus 로고
    • The interplay between the effects of lifetime asthma, smoking, and atopy on fixed airflow obstruction in middle age
    • Perret J., Dharmage S., Matheson M., Johns D., Gurrin L., Burgess J., et al. (2013) The interplay between the effects of lifetime asthma, smoking, and atopy on fixed airflow obstruction in middle age. Am J Respir Crit Care Med 187: 42-48.
    • (2013) Am J Respir Crit Care Med , vol.187 , pp. 42-48
    • Perret, J.1    Dharmage, S.2    Matheson, M.3    Johns, D.4    Gurrin, L.5    Burgess, J.6
  • 78
    • 84942474807 scopus 로고    scopus 로고
    • The asthma-COPD overlap syndrome
    • Postma D., Rabe K., (2015) The asthma-COPD overlap syndrome. N Engl J Med 373: 1241-1249.
    • (2015) N Engl J Med , vol.373 , pp. 1241-1249
    • Postma, D.1    Rabe, K.2
  • 79
    • 84941126995 scopus 로고    scopus 로고
    • Treatment of overlapping asthma-chronic obstructive pulmonary disease: Can guidelines contribute in an evidence-free zone?
    • Reddel H., (2015) Treatment of overlapping asthma-chronic obstructive pulmonary disease: can guidelines contribute in an evidence-free zone? J Allergy Clin Immunol 136: 546-552.
    • (2015) J Allergy Clin Immunol , vol.136 , pp. 546-552
    • Reddel, H.1
  • 80
    • 84897082251 scopus 로고    scopus 로고
    • Medical utilization and cost in patients with overlap syndrome of chronic obstructive pulmonary disease and asthma
    • Rhee C., Yoon H., Yoo K., Kim Y., Lee S., Park Y., et al. (2014) Medical utilization and cost in patients with overlap syndrome of chronic obstructive pulmonary disease and asthma. COPD 11: 163-170.
    • (2014) COPD , vol.11 , pp. 163-170
    • Rhee, C.1    Yoon, H.2    Yoo, K.3    Kim, Y.4    Lee, S.5    Park, Y.6
  • 81
  • 82
    • 37549004387 scopus 로고    scopus 로고
    • Association between neutrophilic airway inflammation and airflow limitation in adults with asthma
    • Shaw D., Berry M., Hargadon B., McKenna S., Shelley M., Green R., et al. (2007) Association between neutrophilic airway inflammation and airflow limitation in adults with asthma. Chest 132: 1871-1875.
    • (2007) Chest , vol.132 , pp. 1871-1875
    • Shaw, D.1    Berry, M.2    Hargadon, B.3    McKenna, S.4    Shelley, M.5    Green, R.6
  • 83
    • 70450213353 scopus 로고    scopus 로고
    • Oncostatin M (OSM) is increased in asthma with incompletely reversible airflow obstruction
    • Simpson J., Baines K., Boyle M., Scott R., Gibson P., (2009) Oncostatin M (OSM) is increased in asthma with incompletely reversible airflow obstruction. Exp Lung Res 35: 781-794.
    • (2009) Exp Lung Res , vol.35 , pp. 781-794
    • Simpson, J.1    Baines, K.2    Boyle, M.3    Scott, R.4    Gibson, P.5
  • 84
    • 34248206610 scopus 로고    scopus 로고
    • Eosinophilic airway inflammation and exacerbations of COPD: A randomised controlled trial
    • Siva R., Green R., Brightling C., Shelley M., Hargadon B., McKenna S., et al. (2007) Eosinophilic airway inflammation and exacerbations of COPD: a randomised controlled trial. Eur Respir J 29: 906-913.
    • (2007) Eur Respir J , vol.29 , pp. 906-913
    • Siva, R.1    Green, R.2    Brightling, C.3    Shelley, M.4    Hargadon, B.5    McKenna, S.6
  • 85
    • 77951134764 scopus 로고    scopus 로고
    • Remodeling in asthma and COPD-differences and similarities
    • Skold C., (2010) Remodeling in asthma and COPD-differences and similarities. Clin Respir J 4 (Suppl. 1): 20-27.
    • (2010) Clin Respir J , vol.4 , pp. 20-27
    • Skold, C.1
  • 86
    • 84907569851 scopus 로고    scopus 로고
    • Common genes underlying asthma and COPD? Genome-wide analysis on the Dutch hypothesis
    • Smolonska J., Koppelman G., Wijmenga C., Vonk J., Zanen P., Bruinenberg M., et al. (2014) Common genes underlying asthma and COPD? Genome-wide analysis on the Dutch hypothesis. Eur Respir J 44: 860-872.
    • (2014) Eur Respir J , vol.44 , pp. 860-872
    • Smolonska, J.1    Koppelman, G.2    Wijmenga, C.3    Vonk, J.4    Zanen, P.5    Bruinenberg, M.6
  • 88
    • 0042231982 scopus 로고    scopus 로고
    • The proportional Venn diagram of obstructive lung disease: Two approximations from the United States and the United Kingdom
    • Soriano J., Davis K., Coleman B., Visick G., Mannino D., Pride N., (2003) The proportional Venn diagram of obstructive lung disease: two approximations from the United States and the United Kingdom. Chest 124: 474-481.
    • (2003) Chest , vol.124 , pp. 474-481
    • Soriano, J.1    Davis, K.2    Coleman, B.3    Visick, G.4    Mannino, D.5    Pride, N.6
  • 89
    • 0029936262 scopus 로고    scopus 로고
    • Methacholine reactivity predicts changes in lung function over time in smokers with early chronic obstructive pulmonary disease. The Lung Health Study Research Group
    • Tashkin D., Altose M., Connett J., Kanner R., Lee W., Wise R., (1996) Methacholine reactivity predicts changes in lung function over time in smokers with early chronic obstructive pulmonary disease. The Lung Health Study Research Group. Am J Respir Crit Care Med 153: 1802-1811.
    • (1996) Am J Respir Crit Care Med , vol.153 , pp. 1802-1811
    • Tashkin, D.1    Altose, M.2    Connett, J.3    Kanner, R.4    Lee, W.5    Wise, R.6
  • 94
    • 60749083583 scopus 로고    scopus 로고
    • Asthma-specific predictors of smoking onset in adolescents with asthma: A longitudinal study
    • Van De Ven M., Engels R., Sawyer S., (2009) Asthma-specific predictors of smoking onset in adolescents with asthma: a longitudinal study. J Pediatr Psychol 34: 118-128.
    • (2009) J Pediatr Psychol , vol.34 , pp. 118-128
    • Van De Ven, M.1    Engels, R.2    Sawyer, S.3
  • 95
    • 0025758520 scopus 로고
    • A 'splitting' look at chronic nonspecific lung disease (CNSLD): Common features but diverse pathogenesis
    • Vermeire P., Pride N., (1991) A 'splitting' look at chronic nonspecific lung disease (CNSLD): common features but diverse pathogenesis. Eur Respir J 4: 490-496.
    • (1991) Eur Respir J , vol.4 , pp. 490-496
    • Vermeire, P.1    Pride, N.2
  • 96
    • 0345701349 scopus 로고    scopus 로고
    • Risk factors associated with the presence of irreversible airflow limitation and reduced transfer coefficient in patients with asthma after 26 years of follow up
    • Vonk J., Jongepier H., Panhuysen C., Schouten J., Bleecker E., Postma D., (2003) Risk factors associated with the presence of irreversible airflow limitation and reduced transfer coefficient in patients with asthma after 26 years of follow up. Thorax 58: 322-327.
    • (2003) Thorax , vol.58 , pp. 322-327
    • Vonk, J.1    Jongepier, H.2    Panhuysen, C.3    Schouten, J.4    Bleecker, E.5    Postma, D.6
  • 97
    • 38349068646 scopus 로고    scopus 로고
    • Systemic inflammation and COPD: The Framingham Heart Study
    • Walter R., Wilk J., Larson M., Vasan R., Keaney J. Jr, Lipinska I., et al. (2008) Systemic inflammation and COPD: the Framingham Heart Study. Chest 133: 19-25.
    • (2008) Chest , vol.133 , pp. 19-25
    • Walter, R.1    Wilk, J.2    Larson, M.3    Vasan, R.4    Keaney, J.5    Lipinska, I.6
  • 98
    • 0032875377 scopus 로고    scopus 로고
    • Evidence that severe asthma can be divided pathologically into two inflammatory subtypes with distinct physiologic and clinical characteristics
    • Wenzel S., Schwartz L., Langmack E., Halliday J., Trudeau J., Gibbs R., et al. (1999) Evidence that severe asthma can be divided pathologically into two inflammatory subtypes with distinct physiologic and clinical characteristics. Am J Respir Crit Care Med 160: 1001-1008.
    • (1999) Am J Respir Crit Care Med , vol.160 , pp. 1001-1008
    • Wenzel, S.1    Schwartz, L.2    Langmack, E.3    Halliday, J.4    Trudeau, J.5    Gibbs, R.6
  • 99
    • 0030859389 scopus 로고    scopus 로고
    • Bronchoscopic evaluation of severe asthma. Persistent inflammation associated with high dose glucocorticoids
    • Wenzel S., Szefler S., Leung D., Sloan S., Rex M., Martin R., (1997) Bronchoscopic evaluation of severe asthma. Persistent inflammation associated with high dose glucocorticoids. Am J Respir Crit Care Med 156: 737-743.
    • (1997) Am J Respir Crit Care Med , vol.156 , pp. 737-743
    • Wenzel, S.1    Szefler, S.2    Leung, D.3    Sloan, S.4    Rex, M.5    Martin, R.6
  • 101
    • 0035813187 scopus 로고    scopus 로고
    • The high molecular weight urinary matrix metalloproteinase (MMP) activity is a complex of gelatinase B/MMP-9 and neutrophil gelatinase-associated lipocalin (NGAL). Modulation of MMP-9 activity by NGAL
    • Yan L., Borregaard N., Kjeldsen L., Moses M., (2001) The high molecular weight urinary matrix metalloproteinase (MMP) activity is a complex of gelatinase B/MMP-9 and neutrophil gelatinase-associated lipocalin (NGAL). Modulation of MMP-9 activity by NGAL. J Biol Chem 276: 37258-37265.
    • (2001) J Biol Chem , vol.276 , pp. 37258-37265
    • Yan, L.1    Borregaard, N.2    Kjeldsen, L.3    Moses, M.4
  • 102
    • 63049104863 scopus 로고    scopus 로고
    • IL6 and CRP haplotypes are associated with COPD risk and systemic inflammation: A case-control study
    • Yanbaeva D., Dentener M., Spruit M., Houwing-Duistermaat J., Kotz D., Passos V., et al. (2009) IL6 and CRP haplotypes are associated with COPD risk and systemic inflammation: a case-control study. BMC Med Genet 10: 23.
    • (2009) BMC Med Genet , vol.10 , pp. 23
    • Yanbaeva, D.1    Dentener, M.2    Spruit, M.3    Houwing-Duistermaat, J.4    Kotz, D.5    Passos, V.6


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