Airway inflammation in asthma with incomplete reversibility to airflow obstruction

Respiratory Medicine

Volumn 97, Issue 6, 2003, Pages 739-744

  Boulet, L P ^a   Turcotte, H ^a   Turcot, O ^a   Chakir, J ^a  

^a LAVAL UNIVERSITY   (Canada)

Author keywords

Airway inflammation; Asthma; Decline of FEV1; Irreversible airflow obstruction; Sputum induction

Indexed keywords

BECLOMETASONE; CORTICOSTEROID; PREDNISONE;

ADULT; AGE; AIRWAY OBSTRUCTION; ARTICLE; ASTHMA; CELL DIFFERENTIATION; CIGARETTE SMOKING; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE DURATION; EOSINOPHIL; FEMALE; FORCED EXPIRATORY VOLUME; HUMAN; LUNG FUNCTION; LYMPHOCYTE; MALE; NEUTROPHIL; PREDICTION; PRIORITY JOURNAL; RECORDING; SPIROMETRY; SPUTUM ANALYSIS;

EID: 0038651182     PISSN: 09546111     EISSN: None     Source Type: Journal    
DOI: 10.1053/rmed.2003.1491     Document Type: Article

References (27)

1. American Thoracic Society Board of Directors. Standards for the diagnosis of patients with COPD and asthma. Am Rev Respir Dis 1987; 136: 225-244.
2. Djukanovic R. Airway inflammation in asthma and its consequences. Implication for treatment in children and adults. J Allergy Clin Immunol 2002; 109: 539-548.
3. Holgate ST. Mediators and cytokine mechanisms in asthma. Thorax 1993; 48:103-9.
4. Djukanovic R, Roche WR, Wilson JW, et al. Mucosal inflammation in asthma. Am Rev Respir Dis 1990; 142: 434-457.
5. Boulet LP, Chakir J, Dubé J, Laprise C, Boutet M, Laviolette M. Airway inflammation and structural changes in airway hyperresponsiveness and asthma: an overview. Can Respir J 1998; 5: 16-21.
6. Boulet LP, Turcotte H, Brochu A. Characteristics of asthma in remission: persistence of airway hyperresponsiveness. Chest 1994; 105: 1024-1031.
7. Juniper EF, Kline PA, Vanzieleghem MA, Ramsdale EH, O'Byrne P, Hargreave FE. Effect of long-term treatment with inhaled corticosteroids on airway hyperresponsiveness and clinical asthma in non steroid-dependent asthmatics. Am Rev Respir Dis 1990; 142: 832-836.
8. Lange P, Parner J, Vestbo J, Schnohr P, Jensen G. A 15-year follow-up study of ventilatory function in adults with asthma. N Engl J Med 1998, 339: 1194-1200.
9. Burrows B. Airway obstructive diseases: pathogenetic mechanisms and natural histories of the disorders. Med Clin North Am 1990; 74: 547-560.
10. Brown PJ, Greville HW, Finucane KE. Asthma and irreversible airflow obstruction. Thorax 1984; 39: 131-236.
11. Boulet LP, Bélanger M, Carrier G. Airway responsiveness and bronchial-wall thickness in asthma with or without fixed airflow obstruction. Am J Resp Crit Care Med 1995; 152: 865-867.
12. Boulet LP, Turcotte H, Hudon C, Carrier G, Maltais F. Clinical, physiological and radiological features of asthma with incomplete reversibility of airflow obstruction compared with those of COPD. Can Respir J 1998; 5: 270-277.
13. Barnes PJ. Chronic obstructive pulmonary disease. N Engl J Med 2000; 343: 269-280.
14. Hudon C, Turcotte H, Laviolette M, Carrier G, Boulet L-P. Characteristics of bronchial asthma with incomplete reversibility of airflow obstruction. Ann Allergy Asthma Immunol 1997; 78: 195-202.
15. Boulet LP, Becker A, Berube D, Beveridge R, Ernst P. Canadian Asthma Consensus Report, 1999. Canadian Asthma Consensus Group. CMAJ 1999; 161 (II Suppl):S161.
16. American Thoracic Society Statement. Snowbird. Workshop in Standardization of Spirometry. Am Rev Respir Dis 1979; 119: 83-8.
17. Knudson RJ, Lebowitz MD, Holberg CJ, et al. Changes in the normal expiratory flow volume curve with growth and aging. Am Rev Respir Dis 1983; 127: 725-734.
18. Pin I, Freitag AP, O'Byrne PM, et al. Changes in the cellular profile of induced sputum after allergen-induced asthmatic responses. Am Rev Respir Dis 1992; 145: 1265-1269.
19. Pizzichini E, Pizzichini MMM, Efthimiadis A, et al. Indices of airway inflammation in induced sputum: reproducibility and validity of cell and fluid phase measurements. Am J Respir Crit Care Med 1996; 154: 308-317.
20. Ulrik CS, Backer V. Nonreversible airflow obstruction in life-long nonsmokers with moderate to severe asthma. Eur Respir J 1999; 14: 892-896.
21. Ulrik CS, Backer VB, Dirksen A. Mortality and decline of lung function in 213 adults with bronchial asthma. A ten-year follow-up. J Asthma 1992; 29: 29-38.
22. Gibson PG. Use of induced sputum to examine airway inflammation in childhood asthma. J Allergy Clin Immunol 1998; 102: S100-1.
23. Ulrik CS, Lange P. Decline of lung function in adults with bronchial asthma. Am J Respir Crit Care Med 1994; 150: 629-634.
24. Little SA, McLoad KJ, Chalmers GW, Love JG, McSharry C, Thomson NC. Association of forced expiratory volume with disease duration and sputum neutrophils in chronic asthma. Am J Med 2002; 112: 446-452.
25. Stanescu D, Sanna A, Veriter C, et al. Airway obstruction, chronic expectoration, and rapid decline of FEV1 in smokers are associated with increased level of sputum neutrophils. Thorax 1996; 51: 267-271.
26. Kraft M, Hamid Q, Chrousos GP, Martin RJ, Leung DY. Decreased steroid responsiveness at night in nocturnal asthma. Ia the macrophage responsible? Am J Respir Crit Care Med 2001; 163: 1219-1225.
27. Mautino G, Henriquet C, Gougat C, et al. Increased expression of tissue inhibitor of metalloproteinase-1 and loss of correlation with matrix metalloproteinase-9 by macrophages in asthma. Lab Invest 1999; 79: 39-47.