Substrate stiffness regulates proinflammatory mediator production through TLR4 activity in macrophages

PLoS ONE

Volumn 10, Issue 12, 2015, Pages

  Previtera, Michelle L ^a,b   Sengupta, Amitabha ^a  

^a NEW JERSEY NEUROSCIENCE INSTITUTE   (United States)

^b SETON HALL UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

I KAPPA B ALPHA; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MYELOID DIFFERENTIATION FACTOR 88; POLYACRYLAMIDE GEL; TOLL LIKE RECEPTOR 4; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6; AUTACOID; I KAPPA B; I KAPPA B KINASE ALPHA; MYD88 PROTEIN, MOUSE; NFKBIA PROTEIN, MOUSE; RELA PROTEIN, MOUSE; TLR4 PROTEIN, MOUSE; TUMOR NECROSIS FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BONE MARROW DERIVED MACROPHAGE; CONTROLLED STUDY; EXTRACELLULAR MATRIX; FEMALE; MOUSE; NONHUMAN; PHYSICAL PARAMETERS; PROINFLAMMATORY MEDIATOR SECRETION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; REGULATORY MECHANISM; SECRETION (PROCESS); SIGNAL TRANSDUCTION; SUBSTRATE STIFFNESS; UPREGULATION; ANIMAL; BIOPHYSICS; CELL CULTURE; ELASTICITY; IMMUNOLOGY; MACROPHAGE; METABOLISM; SURFACE PROPERTY;

ANIMALS; BIOPHYSICAL PHENOMENA; CELLS, CULTURED; ELASTICITY; I-KAPPA B PROTEINS; INFLAMMATION MEDIATORS; MACROPHAGES; MICE; MYELOID DIFFERENTIATION FACTOR 88; NF-KAPPAB INHIBITOR ALPHA; SIGNAL TRANSDUCTION; SURFACE PROPERTIES; TOLL-LIKE RECEPTOR 4; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84957539920     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0145813     Document Type: Article

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