Killer lymphocytes use granulysin, perforin and granzymes to kill intracellular parasites

Nature Medicine

Volumn 22, Issue 2, 2016, Pages 210-216

  Dotiwala, Farokh ^a,b   Mulik, Sachin ^a,b   Polidoro, Rafael B ^a,b,c   Ansara, James A ^a   Burleigh, Barbara A ^d   Walch, Michael ^e   Gazzinelli, Ricardo T ^c,d,f   Lieberman, Judy ^a,b  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c INSTITUTO OSWALDO CRUZ   (Brazil)

^d HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^e UNIVERSITY OF FRIBOURG   (Switzerland)

^f UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GRANULYSIN; GRANZYME; PERFORIN; PHOSPHATIDYLSERINE; SUPEROXIDE; GNLY PROTEIN, HUMAN; GZMA PROTEIN, HUMAN; GZMB PROTEIN, HUMAN; T LYMPHOCYTE ANTIGEN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CHAGAS DISEASE; CHROMATIN CONDENSATION; CONTROLLED STUDY; DNA DAMAGE; ENZYME INACTIVATION; FEMALE; KILLER CELL; LEISHMANIA MAJOR; MALE; MEMBRANE POTENTIAL; MITOCHONDRION SWELLING; MOUSE; NONHUMAN; PRIORITY JOURNAL; TOXOPLASMA GONDII; TOXOPLASMOSIS; TRYPANOSOMA CRUZI; WILD TYPE; ANIMAL; CYTOTOXIC T LYMPHOCYTE; GENETICS; HUMAN; IMMUNOLOGY; NATURAL KILLER CELL; SKIN LEISHMANIASIS; TOXOPLASMA; TRANSGENIC MOUSE;

ANIMALS; ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE; CHAGAS DISEASE; GRANZYMES; HUMANS; KILLER CELLS, NATURAL; LEISHMANIA MAJOR; LEISHMANIASIS, CUTANEOUS; MICE; MICE, TRANSGENIC; PERFORIN; T-LYMPHOCYTES, CYTOTOXIC; TOXOPLASMA; TOXOPLASMOSIS; TRYPANOSOMA CRUZI;

EID: 84957441649     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm.4023     Document Type: Article

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