Differential Effects of Pharmacologic and Genetic Modulation of NMDA Receptor Activity on HIV/gp120-Induced Neuronal Damage in an In Vivo Mouse Model

Journal of Molecular Neuroscience

Volumn 58, Issue 1, 2016, Pages 59-65

  Nakanishi, Nobuki ^a,c   Kang, Yeon Joo ^a   Tu, Shichun ^a   McKercher, Scott R ^a,c   Masliah, Eliezer ^b   Lipton, Stuart A ^a,b,c  

^a BURNHAM INSTITUTE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c SCINTILLON INSTITUTE   (United States)

Author keywords

AIDS; GluN3A; gp120; HIV associated neurocognitive disorder (HAND); Memantine; NitroMemantine; NMDA type glutamate receptors

Indexed keywords

GLUTAMATE RECEPTOR; GLUTAMATE RECEPTOR GLUN3A; GLYCOPROTEIN GP 120; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; NITROMEMANTINE; UNCLASSIFIED DRUG; AMINO ACID RECEPTOR BLOCKING AGENT; GLUN3A PROTEIN, MOUSE; MEMANTINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG INHIBITION; GENE OVEREXPRESSION; GENETIC MANIPULATION; HIPPOCAMPUS; HUMAN IMMUNODEFICIENCY VIRUS; IMMUNOREACTIVITY; IN VIVO STUDY; MOUSE; NERVE CELL LESION; NEUROMODULATION; NEUROPROTECTION; NONHUMAN; PROTEIN FUNCTION; SYNAPSE; TRANSGENICS; AIDS DEMENTIA COMPLEX; ANIMAL; DRUG EFFECTS; GENE THERAPY; GENETICS; METABOLISM; NERVE CELL; PATHOLOGY;

AIDS DEMENTIA COMPLEX; ANIMALS; EXCITATORY AMINO ACID ANTAGONISTS; GENETIC THERAPY; HIV ENVELOPE PROTEIN GP120; MEMANTINE; MICE; NEURONS; RECEPTORS, N-METHYL-D-ASPARTATE;

EID: 84957429808     PISSN: 08958696     EISSN: 15591166     Source Type: Journal    
DOI: 10.1007/s12031-015-0651-1     Document Type: Article

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