Fibrillin-1 Regulates Skeletal Stem Cell Differentiation by Modulating TGFβ Activity Within the Marrow Niche

Journal of Bone and Mineral Research

Volumn 31, Issue 1, 2016, Pages 86-97

  Smaldone, Silvia ^a   Clayton, Nicholas P ^b   Del Solar, Maria ^a   Pascual, Gemma ^c   Cheng, Seng H ^b   Wentworth, Bruce M ^b   Schaffler, Mitchell B ^c,d   Ramirez, Francesco ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b SANOFI   (France)

^c BIOMATERIALES Y NANOMEDICINA CIBER BBN   (Spain)

^d City College of the City University of New York   (United States)

Author keywords

BONE MARROW NICHE; EXTRACELLULAR MATRIX; FIBRILLIN 1; MARFAN SYNDROME; OSTEOPENIA OSTEOPOROSIS; TGF

Indexed keywords

BETA1 INTEGRIN; CASPASE 3; CD45 ANTIGEN; ENDOGLIN; FIBRILLIN 1; INSULIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; TRANSFORMING GROWTH FACTOR BETA; ACTIN BINDING PROTEIN; FBN1 PROTEIN, MOUSE; FIBRILLIN;

ADIPOCYTE; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BONE DEFECT; BONE MARROW; BONE MASS; BONE REMODELING; CELL DIFFERENTIATION; CELL LOSS; CLONOGENESIS; DEGENERATION; DISEASE COURSE; DISEASE SEVERITY; FLOW CYTOMETRY; GENOTYPE; HYPERACTIVITY; LONG BONE; LONGITUDINAL STUDY; MALE; MESENCHYMAL STEM CELL; MESENCHYMAL STROMA CELL; MODULATION; MOUSE; NONHUMAN; OSSIFICATION; OSTEOLYSIS; OSTEOPENIA; OSTEOPROGENITOR CELL; PREMATURITY; RNA INTERFERENCE; TRABECULAR BONE; ANIMAL; GENETICS; KNOCKOUT MOUSE; METABOLISM; PHYSIOLOGY; STEM CELL NICHE;

ANIMALS; BONE MARROW; CELL DIFFERENTIATION; FIBRILLIN-1; FIBRILLINS; MESENCHYMAL STROMAL CELLS; MICE; MICE, KNOCKOUT; MICROFILAMENT PROTEINS; STEM CELL NICHE; TRANSFORMING GROWTH FACTOR BETA;

EID: 84957429163     PISSN: 08840431     EISSN: 15234681     Source Type: Journal    
DOI: 10.1002/jbmr.2598     Document Type: Article

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