Metal Chelation Modulates Phototherapeutic Properties of Mitoxantrone-Loaded Porphyrin-Phospholipid Liposomes

Molecular Pharmaceutics

Volumn 13, Issue 2, 2016, Pages 420-427

  Carter, Kevin A ^a   Wang, Sophie ^a   Geng, Jumin ^a   Luo, Dandan ^a   Shao, Shuai ^a   Lovell, Jonathan F ^a  

^a University at Buffalo The State University of New York   (United States)

Author keywords

Chemophototherapy; light triggered; liposomes; metalloporphyrins; mitoxantrone; photobleaching; porphyrin phospholipid; tumor ablation

Indexed keywords

2 ( 1 HEXYLOXYETHYL) 2 DEVINYLPYROPHENOPHORBIDE ALPHA; COPPER; LIPOSOME; METAL CHELATE; MITOXANTRONE; PHOSPHOLIPID; PHOSPHOLIPID DERIVATIVE; PORPHYRIN PHOSPHOLIPID; REACTIVE OXYGEN METABOLITE; SINGLET OXYGEN; UNCLASSIFIED DRUG; ZINC; PORPHYRIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHELATION; CONTROLLED STUDY; DRUG EFFICACY; DRUG FORMULATION; DRUG RELEASE; DRUG SAFETY; DRUG STABILITY; FEMALE; FLUORESCENCE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LASER; LIPOSOMAL DELIVERY; MOUSE; NEAR INFRARED SPECTROSCOPY; NONHUMAN; PANCREAS CANCER; PHOTOTHERAPY; PHOTOTOXICITY; PRIORITY JOURNAL; PROTEIN SYNTHESIS; TUMOR XENOGRAFT; ANIMAL; CHEMISTRY; DRUG SCREENING; INFRARED RADIATION; MALE; NUDE MOUSE; PANCREATIC NEOPLASMS; PATHOLOGY; TUMOR CELL CULTURE;

ANIMALS; COPPER; HUMANS; INFRARED RAYS; LASERS; LIPOSOMES; MALE; MICE; MICE, NUDE; MITOXANTRONE; PANCREATIC NEOPLASMS; PHOSPHOLIPIDS; PHOTOTHERAPY; PORPHYRINS; SINGLET OXYGEN; TUMOR CELLS, CULTURED; XENOGRAFT MODEL ANTITUMOR ASSAYS; ZINC;

EID: 84957310073     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/acs.molpharmaceut.5b00653     Document Type: Article

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