-
3
-
-
79955921754
-
FOLFIRINOX versus gemcitabine for metastatic pancreatic cancer
-
Conroy T, Desseigne F, Ychou M, Bouche O, Guimbaud R, Becouarn Y, Adenis A, Raoul JL, Gourgou-Bourgade S, de la Fouchardiere C, Bennouna J, Bachet JB, Khemissa-Akouz F, Pere-Verge D, Delbaldo C, Assenat E, Chauffert B, Michel P, Montoto-Grillot C and Ducreux M. FOLFIRINOX versus gemcitabine for metastatic pancreatic cancer. N Engl J Med 2011; 364: 1817-1825.
-
(2011)
N Engl J Med
, vol.364
, pp. 1817-1825
-
-
Conroy, T.1
Desseigne, F.2
Ychou, M.3
Bouche, O.4
Guimbaud, R.5
Becouarn, Y.6
Adenis, A.7
Raoul, J.L.8
Gourgou-Bourgade, S.9
De La Fouchardiere, C.10
Bennouna, J.11
Bachet, J.B.12
Khemissa-Akouz, F.13
Pere-Verge, D.14
Delbaldo, C.15
Assenat, E.16
Chauffert, B.17
Michel, P.18
Montoto-Grillot, C.19
Ducreux, M.20
more..
-
4
-
-
84886741654
-
Increased survival in pancreatic cancer with nab-paclitaxel plus gemcitabine
-
Von Hoff DD, Ervin T, Arena FP, Chiorean EG, Infante J, Moore M, Seay T, Tjulandin SA, Ma WW, Saleh MN, Harris M, Reni M, Dowden S, Laheru D, Bahary N, Ramanathan RK, Tabernero J, Hidalgo M, Goldstein D, Van Cutsem E, Wei X, Iglesias J and Renschler MF. Increased survival in pancreatic cancer with nab-paclitaxel plus gemcitabine. N Engl J Med 2013; 369: 1691-1703.
-
(2013)
N Engl J Med
, vol.369
, pp. 1691-1703
-
-
Von Hoff, D.D.1
Ervin, T.2
Arena, F.P.3
Chiorean, E.G.4
Infante, J.5
Moore, M.6
Seay, T.7
Tjulandin, S.A.8
Ma, W.W.9
Saleh, M.N.10
Harris, M.11
Reni, M.12
Dowden, S.13
Laheru, D.14
Bahary, N.15
Ramanathan, R.K.16
Tabernero, J.17
Hidalgo, M.18
Goldstein, D.19
Van Cutsem, E.20
Wei, X.21
Iglesias, J.22
Renschler, M.F.23
more..
-
5
-
-
84922943712
-
EpCAM and the biology of hepatic stem/progenitor cells
-
Dolle L, Theise ND, Schmelzer E, Boulter L, Gires O and van Grunsven LA. EpCAM and the biology of hepatic stem/progenitor cells. Am J Physiol Gastrointest Liver Physiol 2015; 308: G233-250.
-
(2015)
Am J Physiol Gastrointest Liver Physiol
, vol.308
, pp. G233-G250
-
-
Dolle, L.1
Theise, N.D.2
Schmelzer, E.3
Boulter, L.4
Gires, O.5
Van Grunsven, L.A.6
-
6
-
-
84878005309
-
EpCAM: Structure and function in health and disease
-
Schnell U, Cirulli V and Giepmans BN. EpCAM: structure and function in health and disease. Biochim Biophys Acta 2013; 1828: 1989-2001.
-
(2013)
Biochim Biophys Acta
, vol.1828
, pp. 1989-2001
-
-
Schnell, U.1
Cirulli, V.2
Giepmans, B.N.3
-
8
-
-
78149235833
-
EpCAM in carcinogenesis: The good, the bad or the ugly
-
van der Gun BT, Melchers LJ, Ruiters MH, de Leij LF, McLaughlin PM and Rots MG. EpCAM in carcinogenesis: the good, the bad or the ugly. Carcinogenesis 2010; 31: 1913-1921.
-
(2010)
Carcinogenesis
, vol.31
, pp. 1913-1921
-
-
Van Der Gun, B.T.1
Melchers, L.J.2
Ruiters, M.H.3
De Leij, L.F.4
McLaughlin, P.M.5
Rots, M.G.6
-
9
-
-
84860367617
-
EpCAM and its potential role in tumor-initiating cells
-
Imrich S, Hachmeister M and Gires O. EpCAM and its potential role in tumor-initiating cells. Cell Adh Migr 2012; 6: 30-38.
-
(2012)
Cell Adh Migr
, vol.6
, pp. 30-38
-
-
Imrich, S.1
Hachmeister, M.2
Gires, O.3
-
10
-
-
84876098953
-
Discrete nature of EpCAM+ and CD90+ cancer stem cells in human hepatocellular carcinoma
-
Yamashita T, Honda M, Nakamoto Y, Baba M, Nio K, Hara Y, Zeng SS, Hayashi T, Kondo M, Takatori H, Mizukoshi E, Ikeda H, Zen Y, Takamura H, Wang XW and Kaneko S. Discrete nature of EpCAM+ and CD90+ cancer stem cells in human hepatocellular carcinoma. Hepatology 2013; 57: 1484-1497.
-
(2013)
Hepatology
, vol.57
, pp. 1484-1497
-
-
Yamashita, T.1
Honda, M.2
Nakamoto, Y.3
Baba, M.4
Nio, K.5
Hara, Y.6
Zeng, S.S.7
Hayashi, T.8
Kondo, M.9
Takatori, H.10
Mizukoshi, E.11
Ikeda, H.12
Zen, Y.13
Takamura, H.14
Wang, X.W.15
Kaneko, S.16
-
11
-
-
33847052127
-
Identification of pancreatic cancer stem cells
-
Li C, Heidt DG, Dalerba P, Burant CF, Zhang L, Adsay V, Wicha M, Clarke MF and Simeone DM. Identification of pancreatic cancer stem cells. Cancer Res 2007; 67: 1030-1037.
-
(2007)
Cancer Res
, vol.67
, pp. 1030-1037
-
-
Li, C.1
Heidt, D.G.2
Dalerba, P.3
Burant, C.F.4
Zhang, L.5
Adsay, V.6
Wicha, M.7
Clarke, M.F.8
Simeone, D.M.9
-
12
-
-
38449097632
-
Ep-CAM expression in pancreatic and ampullary carcinomas: Frequency and prognostic relevance
-
Fong D, Steurer M, Obrist P, Barbieri V, Margreiter R, Amberger A, Laimer K, Gastl G, Tzankov A and Spizzo G. Ep-CAM expression in pancreatic and ampullary carcinomas: frequency and prognostic relevance. J Clin Pathol 2008; 61: 31-35.
-
(2008)
J Clin Pathol
, vol.61
, pp. 31-35
-
-
Fong, D.1
Steurer, M.2
Obrist, P.3
Barbieri, V.4
Margreiter, R.5
Amberger, A.6
Laimer, K.7
Gastl, G.8
Tzankov, A.9
Spizzo, G.10
-
13
-
-
79961166877
-
Ep-CAM is a significant prognostic factor in pancreatic cancer patients by suppressing cell activity
-
Akita H, Nagano H, Takeda Y, Eguchi H, Wada H, Kobayashi S, Marubashi S, Tanemura M, Takahashi H, Ohigashi H, Tomita Y, Ishikawa O, Mori M and Doki Y. Ep-CAM is a significant prognostic factor in pancreatic cancer patients by suppressing cell activity. Oncogene 2011; 30: 3468-3476.
-
(2011)
Oncogene
, vol.30
, pp. 3468-3476
-
-
Akita, H.1
Nagano, H.2
Takeda, Y.3
Eguchi, H.4
Wada, H.5
Kobayashi, S.6
Marubashi, S.7
Tanemura, M.8
Takahashi, H.9
Ohigashi, H.10
Tomita, Y.11
Ishikawa, O.12
Mori, M.13
Doki, Y.14
-
14
-
-
33947283773
-
Loss of membranous Ep-CAM in budding colorectal carcinoma cells
-
Gosens MJ, van Kempen LC, van de Velde CJ, van Krieken JH and Nagtegaal ID. Loss of membranous Ep-CAM in budding colorectal carcinoma cells. Mod Pathol 2007; 20: 221-232.
-
(2007)
Mod Pathol
, vol.20
, pp. 221-232
-
-
Gosens, M.J.1
Van Kempen, L.C.2
Van De Velde, C.J.3
Van Krieken, J.H.4
Nagtegaal, I.D.5
-
15
-
-
84870445093
-
Cytoplasmic Trop-1/Ep-CAM overexpression is associated with a favorable outcome in node-positive breast cancer
-
Alberti S, Ambrogi F, Boracchi P, Fornili M, Querzoli P, Pedriali M, La Sorda R, Lattanzio R, Tripaldi R, Piantelli M, Biganzoli E and Coradini D. Cytoplasmic Trop-1/Ep-CAM overexpression is associated with a favorable outcome in node-positive breast cancer. Jpn J Clin Oncol 2012; 42: 1128-1137.
-
(2012)
Jpn J Clin Oncol
, vol.42
, pp. 1128-1137
-
-
Alberti, S.1
Ambrogi, F.2
Boracchi, P.3
Fornili, M.4
Querzoli, P.5
Pedriali, M.6
La Sorda, R.7
Lattanzio, R.8
Tripaldi, R.9
Piantelli, M.10
Biganzoli, E.11
Coradini, D.12
-
16
-
-
84904318442
-
Concurrent CD44s and STAT3 expression in human clear cell renal cellular carcinoma and its impact on survival
-
Qin J, Yang B, Xu BQ, Smithc A, Xu L, Yuan JL and Li L. Concurrent CD44s and STAT3 expression in human clear cell renal cellular carcinoma and its impact on survival. Int J Clin Exp Pathol 2014; 7: 3235-3244.
-
(2014)
Int J Clin Exp Pathol
, vol.7
, pp. 3235-3244
-
-
Qin, J.1
Yang, B.2
Xu, B.Q.3
Smithc, A.4
Xu, L.5
Yuan, J.L.6
Li, L.7
-
17
-
-
84890597865
-
HAb18G/CD147 promotes pSTAT3-mediated pancreatic cancer development via CD44s
-
Li L, Tang W, Wu X, Karnak D, Meng X, Thompson R, Hao X, Li Y, Qiao XT, Lin J, Fuchs J, Simeone DM, Chen ZN, Lawrence TS and Xu L. HAb18G/CD147 promotes pSTAT3-mediated pancreatic cancer development via CD44s. Clin Cancer Res 2013; 19: 6703-6715.
-
(2013)
Clin Cancer Res
, vol.19
, pp. 6703-6715
-
-
Li, L.1
Tang, W.2
Wu, X.3
Karnak, D.4
Meng, X.5
Thompson, R.6
Hao, X.7
Li, Y.8
Qiao, X.T.9
Lin, J.10
Fuchs, J.11
Simeone, D.M.12
Chen, Z.N.13
Lawrence, T.S.14
Xu, L.15
-
18
-
-
84896489722
-
Antibody against CD44s inhibits pancreatic tumor initiation and postradiation recurrence in mice
-
Li L, Hao X, Qin J, Tang W, He F, Smith A, Zhang M, Simeone DM, Qiao XT, Chen ZN, Lawrence TS and Xu L. Antibody against CD44s inhibits pancreatic tumor initiation and postradiation recurrence in mice. Gastroenterology 2014; 146: 1108-1118.
-
(2014)
Gastroenterology
, vol.146
, pp. 1108-1118
-
-
Li, L.1
Hao, X.2
Qin, J.3
Tang, W.4
He, F.5
Smith, A.6
Zhang, M.7
Simeone, D.M.8
Qiao, X.T.9
Chen, Z.N.10
Lawrence, T.S.11
Xu, L.12
-
19
-
-
67649637824
-
Sulforaphane targets pancreatic tumour-initiating cells by NF-kappaB-induced antiapoptotic signalling
-
Kallifatidis G, Rausch V, Baumann B, Apel A, Beckermann BM, Groth A, Mattern J, Li Z, Kolb A, Moldenhauer G, Altevogt P, Wirth T, Werner J, Schemmer P, Buchler MW, Salnikov AV and Herr I. Sulforaphane targets pancreatic tumour-initiating cells by NF-kappaB-induced antiapoptotic signalling. Gut 2009; 58: 949-963.
-
(2009)
Gut
, vol.58
, pp. 949-963
-
-
Kallifatidis, G.1
Rausch, V.2
Baumann, B.3
Apel, A.4
Beckermann, B.M.5
Groth, A.6
Mattern, J.7
Li, Z.8
Kolb, A.9
Moldenhauer, G.10
Altevogt, P.11
Wirth, T.12
Werner, J.13
Schemmer, P.14
Buchler, M.W.15
Salnikov, A.V.16
Herr, I.17
-
20
-
-
84943328547
-
Cleavage and Cell Adhesion Properties of Human Epithelial Cell Adhesion Molecule (HEPCAM)
-
Tsaktanis T, Kremling H, Pavsic M, von Stackelberg R, Mack B, Fukumori A, Steiner H, Vielmuth F, Spindler V, Huang Z, Jakubowski J, Stoecklein NH, Luxenburger E, Lauber K, Lenarcic B and Gires O. Cleavage and Cell Adhesion Properties of Human Epithelial Cell Adhesion Molecule (HEPCAM). J Biol Chem 2015; 290: 24574-24591.
-
(2015)
J Biol Chem
, vol.290
, pp. 24574-24591
-
-
Tsaktanis, T.1
Kremling, H.2
Pavsic, M.3
Von Stackelberg, R.4
Mack, B.5
Fukumori, A.6
Steiner, H.7
Vielmuth, F.8
Spindler, V.9
Huang, Z.10
Jakubowski, J.11
Stoecklein, N.H.12
Luxenburger, E.13
Lauber, K.14
Lenarcic, B.15
Gires, O.16
-
21
-
-
70349512496
-
EpCAM-targeted delivery of nanocomplexed siRNA to tumor cells with designed ankyrin repeat proteins
-
Winkler J, Martin-Killias P, Pluckthun A and Zangemeister-Wittke U. EpCAM-targeted delivery of nanocomplexed siRNA to tumor cells with designed ankyrin repeat proteins. Mol Cancer Ther 2009; 8: 2674-2683.
-
(2009)
Mol Cancer Ther
, vol.8
, pp. 2674-2683
-
-
Winkler, J.1
Martin-Killias, P.2
Pluckthun, A.3
Zangemeister-Wittke, U.4
-
22
-
-
38349107593
-
The Alzheimer’s disease beta-secretase enzyme, BACE1
-
Cole SL and Vassar R. The Alzheimer’s disease beta-secretase enzyme, BACE1. Mol Neurodegener 2007; 2: 22.
-
(2007)
Mol Neurodegener
, vol.2
, pp. 22
-
-
Cole, S.L.1
Vassar, R.2
-
23
-
-
84885532962
-
Context-dependent adaption of EpCAM expression in early systemic esophageal cancer
-
Driemel C, Kremling H, Schumacher S, Will D, Wolters J, Lindenlauf N, Mack B, Baldus SA, Hoya V, Pietsch JM, Panagiotidou P, Raba K, Vay C, Vallbohmer D, Harreus U, Knoefel WT, Stoecklein NH and Gires O. Context-dependent adaption of EpCAM expression in early systemic esophageal cancer. Oncogene 2014; 33: 4904-4915.
-
(2014)
Oncogene
, vol.33
, pp. 4904-4915
-
-
Driemel, C.1
Kremling, H.2
Schumacher, S.3
Will, D.4
Wolters, J.5
Lindenlauf, N.6
Mack, B.7
Baldus, S.A.8
Hoya, V.9
Pietsch, J.M.10
Panagiotidou, P.11
Raba, K.12
Vay, C.13
Vallbohmer, D.14
Harreus, U.15
Knoefel, W.T.16
Stoecklein, N.H.17
Gires, O.18
-
24
-
-
59749103834
-
Nuclear signalling by tumour-associated antigen EpCAM
-
Maetzel D, Denzel S, Mack B, Canis M, Went P, Benk M, Kieu C, Papior P, Baeuerle PA, Munz M and Gires O. Nuclear signalling by tumour-associated antigen EpCAM. Nat Cell Biol 2009; 11: 162-171.
-
(2009)
Nat Cell Biol
, vol.11
, pp. 162-171
-
-
Maetzel, D.1
Denzel, S.2
Mack, B.3
Canis, M.4
Went, P.5
Benk, M.6
Kieu, C.7
Papior, P.8
Baeuerle, P.A.9
Munz, M.10
Gires, O.11
-
25
-
-
84896138209
-
Loss of membranous expression of the intracellular domain of EpCAM is a frequent event and predicts poor survival in patients with pancreatic cancer
-
Fong D, Moser P, Kasal A, Seeber A, Gastl G, Martowicz A, Wurm M, Mian C, Obrist P, Mazzoleni G and Spizzo G. Loss of membranous expression of the intracellular domain of EpCAM is a frequent event and predicts poor survival in patients with pancreatic cancer. Histopathology 2014; 64: 683-692.
-
(2014)
Histopathology
, vol.64
, pp. 683-692
-
-
Fong, D.1
Moser, P.2
Kasal, A.3
Seeber, A.4
Gastl, G.5
Martowicz, A.6
Wurm, M.7
Mian, C.8
Obrist, P.9
Mazzoleni, G.10
Spizzo, G.11
-
26
-
-
84898823986
-
Expression of EpCAM (MF) and EpCAM (MT) variants in human carcinomas
-
Fong D, Seeber A, Terracciano L, Kasal A, Mazzoleni G, Lehne F, Gastl G and Spizzo G. Expression of EpCAM (MF) and EpCAM (MT) variants in human carcinomas. J Clin Pathol 2014; 67: 408-414.
-
(2014)
J Clin Pathol
, vol.67
, pp. 408-414
-
-
Fong, D.1
Seeber, A.2
Terracciano, L.3
Kasal, A.4
Mazzoleni, G.5
Lehne, F.6
Gastl, G.7
Spizzo, G.8
-
27
-
-
84925285931
-
Dynamic EpCAM expression on circulating and disseminating tumor cells: Causes and consequences
-
Gires O and Stoecklein NH. Dynamic EpCAM expression on circulating and disseminating tumor cells: causes and consequences. Cell Mol Life Sci 2014; 71: 4393-4402.
-
(2014)
Cell Mol Life Sci
, vol.71
, pp. 4393-4402
-
-
Gires, O.1
Stoecklein, N.H.2
-
28
-
-
0034893924
-
Rare occurrence of metastatic colorectal cancers in livers with replicative hepatitis B infection
-
Song E, Chen J, Ou Q and Su F. Rare occurrence of metastatic colorectal cancers in livers with replicative hepatitis B infection. Am J Surg 2001; 181: 529-533.
-
(2001)
Am J Surg
, vol.181
, pp. 529-533
-
-
Song, E.1
Chen, J.2
Ou, Q.3
Su, F.4
-
29
-
-
84885014541
-
The status of HBV infection influences metastatic pattern and survival in Chinese patients with pancreatic cancer
-
Wei XL, Qiu MZ, Chen WW, Jin Y, Ren C, Wang F, Luo HY, Wang ZQ, Zhang DS, Wang FH, Li YH and Xu RH. The status of HBV infection influences metastatic pattern and survival in Chinese patients with pancreatic cancer. J Transl Med 2013; 11: 249.
-
(2013)
J Transl Med
, vol.11
, pp. 249
-
-
Wei, X.L.1
Qiu, M.Z.2
Chen, W.W.3
Jin, Y.4
Ren, C.5
Wang, F.6
Luo, H.Y.7
Wang, Z.Q.8
Zhang, D.S.9
Wang, F.H.10
Li, Y.H.11
Xu, R.H.12
-
30
-
-
84941187056
-
Risk of alltype cancer, hepatocellular carcinoma, non-Hodgkin lymphoma and pancreatic cancer in patients infected with hepatitis B virus
-
Andersen ES, Omland LH, Jepsen P, Krarup H, Christensen PB, Obel N and Weis N. Risk of alltype cancer, hepatocellular carcinoma, non-Hodgkin lymphoma and pancreatic cancer in patients infected with hepatitis B virus. J Viral Hepat 2015; 22: 828-834.
-
(2015)
J Viral Hepat
, vol.22
, pp. 828-834
-
-
Ersen, E.S.1
Omland, L.H.2
Jepsen, P.3
Krarup, H.4
Christensen, P.B.5
Obel, N.6
Weis, N.7
-
31
-
-
84939633114
-
Impact of Hepatitis B Virus on Clinicopathological Features and Outcomes After Resection for Pancreatic Adenocarcinoma
-
Dumitrascu T, Pineau P, Dima S, Stroescu C, Brasoveanu V, Herlea V, Ionescu M and Popescu I. Impact of Hepatitis B Virus on Clinicopathological Features and Outcomes After Resection for Pancreatic Adenocarcinoma. Anticancer Res 2015; 35: 5123-5128.
-
(2015)
Anticancer Res
, vol.35
, pp. 5123-5128
-
-
Dumitrascu, T.1
Pineau, P.2
Dima, S.3
Stroescu, C.4
Brasoveanu, V.5
Herlea, V.6
Ionescu, M.7
Popescu, I.8
-
32
-
-
77950619377
-
Risk of pancreatic cancer in chronic hepatitis B virus infection: Data from the REVEAL-HBV cohort study
-
Iloeje UH, Yang HI, Jen CL, Su J, Wang LY, You SL, Lu SN and Chen CJ. Risk of pancreatic cancer in chronic hepatitis B virus infection: data from the REVEAL-HBV cohort study. Liver Int 2010; 30: 423-429.
-
(2010)
Liver Int
, vol.30
, pp. 423-429
-
-
Iloeje, U.H.1
Yang, H.I.2
Jen, C.L.3
Su, J.4
Wang, L.Y.5
You, S.L.6
Lu, S.N.7
Chen, C.J.8
-
33
-
-
84958051719
-
Hepatitis B virus X protein induces EpCAM expression via active DNA demethylation directed by RelA in complex with EZH2 and TET2
-
[Epub ahead of print]
-
Fan H, Zhang H, Pascuzzi PE and Andrisani O. Hepatitis B virus X protein induces EpCAM expression via active DNA demethylation directed by RelA in complex with EZH2 and TET2. Oncogene 2015; [Epub ahead of print].
-
(2015)
Oncogene
-
-
Fan, H.1
Zhang, H.2
Pascuzzi, P.E.3
Andrisani, O.4
-
34
-
-
84896126810
-
Expression of EpCAM increases in the hepatitis B related and the treatmentresistant hepatocellular carcinoma
-
2014
-
Kimura O, Kondo Y, Kogure T, Kakazu E, Ninomiya M, Iwata T, Morosawa T and Shimosegawa T. Expression of EpCAM increases in the hepatitis B related and the treatmentresistant hepatocellular carcinoma. Biomed Res Int 2014; 2014: 172913.
-
(2014)
Biomed Res Int
-
-
Kimura, O.1
Kondo, Y.2
Kogure, T.3
Kakazu, E.4
Ninomiya, M.5
Iwata, T.6
Morosawa, T.7
Shimosegawa, T.8
-
35
-
-
79956079665
-
Does the hepatitis B antigen HBx promote the appearance of liver cancer stem cells?
-
Arzumanyan A, Friedman T, Ng IO, Clayton MM, Lian Z and Feitelson MA. Does the hepatitis B antigen HBx promote the appearance of liver cancer stem cells? Cancer Res 2011; 71: 3701-3708.
-
(2011)
Cancer Res
, vol.71
, pp. 3701-3708
-
-
Arzumanyan, A.1
Friedman, T.2
Ng, I.O.3
Clayton, M.M.4
Lian, Z.5
Feitelson, M.A.6
|