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Volumn 48, Issue 2, 2016, Pages 734-746

A novel combination of oridonin and valproic acid in enhancement of apoptosis induction of HL-60 leukemia cells

Author keywords

Apoptosis; Caspase; Leukemia; MAPK; Oridonin; Valproic acid

Indexed keywords

BETA ACTIN; CASPASE 3; CASPASE 8; CASPASE 9; CYTOCHROME C; FAS ANTIGEN; ORIDONIN; PROTEIN BAX; PROTEIN BCL 2; VALPROIC ACID; FAS LIGAND; FASLG PROTEIN, HUMAN; KAURANE DERIVATIVE;

EID: 84956954296     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo.2015.3294     Document Type: Article
Times cited : (16)

References (38)
  • 1
    • 84883133740 scopus 로고    scopus 로고
    • Management of elderly patients with acute promyelocytic leukemia: Progress and problems
    • Lengfelder E, Hofmann WK and Nolte F: Management of elderly patients with acute promyelocytic leukemia: Progress and problems. Ann Hematol 92: 1181-1188, 2013.
    • (2013) Ann Hematol , vol.92 , pp. 1181-1188
    • Lengfelder, E.1    Hofmann, W.K.2    Nolte, F.3
  • 2
    • 0035143574 scopus 로고    scopus 로고
    • Treatment of acute promyelocytic leukemia with arsenic compounds: In vitro and in vivo studies
    • Chen Z, Chen GQ, Shen ZX, Chen SJ and Wang ZY: Treatment of acute promyelocytic leukemia with arsenic compounds: In vitro and in vivo studies. Semin Hematol 38: 26-36, 2001.
    • (2001) Semin Hematol , vol.38 , pp. 26-36
    • Chen, Z.1    Chen, G.Q.2    Shen, Z.X.3    Chen, S.J.4    Wang, Z.Y.5
  • 4
    • 84876006053 scopus 로고    scopus 로고
    • Epidemiology, diagnosis and treatment of acute promyelocytic leukemia in children: The experience in China
    • Zhang L and Zhu X: Epidemiology, diagnosis and treatment of acute promyelocytic leukemia in children: The experience in china. Mediterr J Hematol Infect Dis 4: e2012012, 2012.
    • (2012) Mediterr J Hematol Infect Dis , vol.4 , pp. e2012012
    • Zhang, L.1    Zhu, X.2
  • 5
    • 0036720177 scopus 로고    scopus 로고
    • Management of acute promyelocytic leukemia
    • Tallman MS and Nabhan C: Management of acute promyelocytic leukemia. Curr Oncol Rep 4: 381-389, 2002.
    • (2002) Curr Oncol Rep , vol.4 , pp. 381-389
    • Tallman, M.S.1    Nabhan, C.2
  • 6
    • 0036288419 scopus 로고    scopus 로고
    • Advances in the treatment of relapsed acute promyelocytic leukemia
    • Douer D: Advances in the treatment of relapsed acute promyelocytic leukemia. Acta Haematol 107: 1-17, 2002.
    • (2002) Acta Haematol , vol.107 , pp. 1-17
    • Douer, D.1
  • 7
    • 0036464594 scopus 로고    scopus 로고
    • Acute promyelocytic leukemia: Evolving therapeutic strategies
    • Tallman MS, Nabhan C, Feusner JH and Rowe JM: Acute promyelocytic leukemia: Evolving therapeutic strategies. Blood 99: 759-767, 2002.
    • (2002) Blood , vol.99 , pp. 759-767
    • Tallman, M.S.1    Nabhan, C.2    Feusner, J.H.3    Rowe, J.M.4
  • 8
    • 0042329147 scopus 로고    scopus 로고
    • Choice of chemotherapy in induction, consolidation and maintenance in acute promyelocytic leukaemia
    • Sanz MA, Martín G and Lo Coco F: Choice of chemotherapy in induction, consolidation and maintenance in acute promyelocytic leukaemia. Best Pract Res Clin Haematol 16: 433-451, 2003.
    • (2003) Best Pract Res Clin Haematol , vol.16 , pp. 433-451
    • Sanz, M.A.1    Martín, G.2    Lo Coco, F.3
  • 10
    • 84879156094 scopus 로고    scopus 로고
    • Mechanisms of action and resistance to all-trans retinoic acid (ATRA) and arsenic trioxide (As2O3) in acute promyelocytic leukemia
    • Tomita A, Kiyoi H and Naoe T: Mechanisms of action and resistance to all-trans retinoic acid (ATRA) and arsenic trioxide (As2O3) in acute promyelocytic leukemia. Int J Hematol 97: 717-725, 2013.
    • (2013) Int J Hematol , vol.97 , pp. 717-725
    • Tomita, A.1    Kiyoi, H.2    Naoe, T.3
  • 11
    • 0001483546 scopus 로고
    • Acute promyelocytic leukemia
    • Hillestad LK: Acute promyelocytic leukemia. Acta Med Scand 159: 189-194, 1957.
    • (1957) Acta Med Scand , vol.159 , pp. 189-194
    • Hillestad, L.K.1
  • 12
    • 7444252185 scopus 로고    scopus 로고
    • Antiproliferation effects of oridonin on HL-60 cells
    • Liu JJ, Wu XY, Peng J, Pan XL and Lu HL: Antiproliferation effects of oridonin on HL-60 cells. Ann Hematol 83: 691-695, 2004.
    • (2004) Ann Hematol , vol.83 , pp. 691-695
    • Liu, J.J.1    Wu, X.Y.2    Peng, J.3    Pan, X.L.4    Lu, H.L.5
  • 13
    • 77249161819 scopus 로고    scopus 로고
    • Apoptosis inducing and differentiation enhancement effect of oridonin on the all-trans-retinoic acid-sensitive and-resistant acute promyelocytic leukemia cells
    • Gao F, Tang Q, Yang P, Fang Y, Li W and Wu Y: Apoptosis inducing and differentiation enhancement effect of oridonin on the all-trans-retinoic acid-sensitive and-resistant acute promyelocytic leukemia cells. Int J Lab Hematol 32 (1p1): e114-e122, 2010.
    • (2010) Int J Lab Hematol , vol.32 , Issue.1 P1 , pp. e114-e122
    • Gao, F.1    Tang, Q.2    Yang, P.3    Fang, Y.4    Li, W.5    Wu, Y.6
  • 14
    • 34147131374 scopus 로고    scopus 로고
    • Oridonin, a diterpenoid extracted from medicinal herbs, targets AML1-ETO fusion protein and shows potent antitumor activity with low adverse effects on t(8;21) leukemia in vitro and in vivo
    • Zhou GB, Kang H, Wang L, Gao L, Liu P, Xie J, Zhang FX, Weng XQ, Shen ZX, Chen J, et al: Oridonin, a diterpenoid extracted from medicinal herbs, targets AML1-ETO fusion protein and shows potent antitumor activity with low adverse effects on t(8;21) leukemia in vitro and in vivo. Blood 109: 3441-3450, 2007.
    • (2007) Blood , vol.109 , pp. 3441-3450
    • Zhou, G.B.1    Kang, H.2    Wang, L.3    Gao, L.4    Liu, P.5    Xie, J.6    Zhang, F.X.7    Weng, X.Q.8    Shen, Z.X.9    Chen, J.10
  • 15
    • 78049385776 scopus 로고    scopus 로고
    • Oridonin induces apoptosis and senescence in colorectal cancer cells by increasing histone hyperacetylation and regulation of p16, p21, p27 and c-myc
    • Gao FH, Hu XH, Li W, Liu H, Zhang YJ, Guo ZY, Xu MH, Wang ST, Jiang B, Liu F, et al: Oridonin induces apoptosis and senescence in colorectal cancer cells by increasing histone hyperacetylation and regulation of p16, p21, p27 and c-myc. BMC Cancer 10: 610, 2010.
    • (2010) BMC Cancer , vol.10 , pp. 610
    • Gao, F.H.1    Hu, X.H.2    Li, W.3    Liu, H.4    Zhang, Y.J.5    Guo, Z.Y.6    Xu, M.H.7    Wang, S.T.8    Jiang, B.9    Liu, F.10
  • 16
    • 84455163076 scopus 로고    scopus 로고
    • Synergistic antitumor activity of oridonin and arsenic trioxide on hepatocellular carcinoma cells
    • Chen G, Wang K, Yang BY, Tang B, Chen JX and Hua ZC: Synergistic antitumor activity of oridonin and arsenic trioxide on hepatocellular carcinoma cells. Int J Oncol 40: 139-147, 2012.
    • (2012) Int J Oncol , vol.40 , pp. 139-147
    • Chen, G.1    Wang, K.2    Yang, B.Y.3    Tang, B.4    Chen, J.X.5    Hua, Z.C.6
  • 17
    • 0034596309 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors: Inducers of differentiation or apoptosis of transformed cells
    • Marks PA, Richon VM and Rifkind RA: Histone deacetylase inhibitors: Inducers of differentiation or apoptosis of transformed cells. J Natl Cancer Inst 92: 1210-1216, 2000.
    • (2000) J Natl Cancer Inst , vol.92 , pp. 1210-1216
    • Marks, P.A.1    Richon, V.M.2    Rifkind, R.A.3
  • 18
    • 23744501131 scopus 로고    scopus 로고
    • The novel triterpenoid CDDO-Me suppresses MAPK pathways and promotes p38 activation in acute myeloid leukemia cells
    • Konopleva M, Contractor R, Kurinna SM, Chen W, Andreeff M and Ruvolo PP: The novel triterpenoid CDDO-Me suppresses MAPK pathways and promotes p38 activation in acute myeloid leukemia cells. Leukemia 19: 1350-1354, 2005.
    • (2005) Leukemia , vol.19 , pp. 1350-1354
    • Konopleva, M.1    Contractor, R.2    Kurinna, S.M.3    Chen, W.4    Andreeff, M.5    Ruvolo, P.P.6
  • 19
    • 0035965343 scopus 로고    scopus 로고
    • Histone deacetylase is a direct target of valproic acid, a potent anticonvulsant, mood stabilizer, and teratogen
    • Phiel CJ, Zhang F, Huang EY, Guenther mg, Lazar MA and Klein PS: Histone deacetylase is a direct target of valproic acid, a potent anticonvulsant, mood stabilizer, and teratogen. J Biol Chem 276: 36734-36741, 2001.
    • (2001) J Biol Chem , vol.276 , pp. 36734-36741
    • Phiel, C.J.1    Zhang, F.2    Huang, E.Y.3    Mg, G.4    Lazar, M.A.5    Klein, P.S.6
  • 20
    • 33748997409 scopus 로고    scopus 로고
    • Sequential valproic acid/all-trans retinoic acid treatment reprograms differentiation in refractory and high-risk acute myeloid leukemia
    • Cimino G, Lo-Coco F, Fenu S, Travaglini L, Finolezzi E, Mancini M, Nanni M, Careddu A, Fazi F, Padula F, et al: Sequential valproic acid/all-trans retinoic acid treatment reprograms differentiation in refractory and high-risk acute myeloid leukemia. Cancer Res 66: 8903-8911, 2006.
    • (2006) Cancer Res , vol.66 , pp. 8903-8911
    • Cimino, G.1    Lo-Coco, F.2    Fenu, S.3    Travaglini, L.4    Finolezzi, E.5    Mancini, M.6    Nanni, M.7    Careddu, A.8    Fazi, F.9    Padula, F.10
  • 21
    • 3142692649 scopus 로고    scopus 로고
    • Valproic acid inhibits proliferation and induces apoptosis in acute myeloid leukemia cells expressing P-gp and MRP1
    • Tang R, Faussat AM, Majdak P, Perrot JY, Chaoui D, Legrand O and Marie JP: Valproic acid inhibits proliferation and induces apoptosis in acute myeloid leukemia cells expressing P-gp and MRP1. Leukemia 18: 1246-1251, 2004.
    • (2004) Leukemia , vol.18 , pp. 1246-1251
    • Tang, R.1    Faussat, A.M.2    Majdak, P.3    Perrot, J.Y.4    Chaoui, D.5    Legrand, O.6    Marie, J.P.7
  • 22
    • 33748794547 scopus 로고    scopus 로고
    • Theoretical basis, experimental design, and computerized simulation of synergism and antagonism in drug combination studies
    • Chou TC: Theoretical basis, experimental design, and computerized simulation of synergism and antagonism in drug combination studies. Pharmacol Rev 58: 621-681, 2006.
    • (2006) Pharmacol Rev , vol.58 , pp. 621-681
    • Chou, T.C.1
  • 23
    • 34249748770 scopus 로고    scopus 로고
    • Down-regulation of CD44 contributes to the differentiation of HL-60 cells induced by ATRA or HMBA
    • Liu J, Bi G, Wen P, Yang W, Ren X, Tang T, Xie C, Dong W and Jiang G: Down-regulation of CD44 contributes to the differentiation of HL-60 cells induced by ATRA or HMBA. Cell Mol Immunol 4: 59-63, 2007.
    • (2007) Cell Mol Immunol , vol.4 , pp. 59-63
    • Liu, J.1    Bi, G.2    Wen, P.3    Yang, W.4    Ren, X.5    Tang, T.6    Xie, C.7    Dong, W.8    Jiang, G.9
  • 24
    • 0033519705 scopus 로고    scopus 로고
    • Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC
    • Shimizu S, Narita M and Tsujimoto Y: Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC. Nature 399: 483-487, 1999.
    • (1999) Nature , vol.399 , pp. 483-487
    • Shimizu, S.1    Narita, M.2    Tsujimoto, Y.3
  • 25
    • 70349145859 scopus 로고    scopus 로고
    • Caspaseindependent pathways of programmed cell death: The unraveling of new targets of cancer therapy?
    • Constantinou C, Papas KA and Constantinou AI: Caspaseindependent pathways of programmed cell death: The unraveling of new targets of cancer therapy? Curr Cancer Drug Targets 9: 717-728, 2009.
    • (2009) Curr Cancer Drug Targets , vol.9 , pp. 717-728
    • Constantinou, C.1    Papas, K.A.2    Constantinou, A.I.3
  • 27
    • 84899067617 scopus 로고    scopus 로고
    • Oridonin induces apoptosis and cell cycle arrest of gallbladder cancer cells via the mitochondrial pathway
    • Bao R, Shu Y, Wu X, Weng H, Ding Q, Cao Y, Li M, Mu J, Wu W, Ding Q, et al: Oridonin induces apoptosis and cell cycle arrest of gallbladder cancer cells via the mitochondrial pathway. BMC Cancer 14: 217, 2014.
    • (2014) BMC Cancer , vol.14 , pp. 217
    • Bao, R.1    Shu, Y.2    Wu, X.3    Weng, H.4    Ding, Q.5    Cao, Y.6    Li, M.7    Mu, J.8    Wu, W.9    Ding, Q.10
  • 28
    • 0036201888 scopus 로고    scopus 로고
    • Valproic acid induces apoptosis in human leukemia cells by stimulating both caspasedependent and-independent apoptotic signaling pathways
    • Kawagoe R, Kawagoe H and Sano K: Valproic acid induces apoptosis in human leukemia cells by stimulating both caspasedependent and-independent apoptotic signaling pathways. Leuk Res 26: 495-502, 2002.
    • (2002) Leuk Res , vol.26 , pp. 495-502
    • Kawagoe, R.1    Kawagoe, H.2    Sano, K.3
  • 29
    • 48649095089 scopus 로고    scopus 로고
    • Cancer chemoprevention and chemotherapy: Dietary polyphenols and signalling pathways
    • Ramos S: Cancer chemoprevention and chemotherapy: Dietary polyphenols and signalling pathways. Mol Nutr Food Res 52: 507-526, 2008.
    • (2008) Mol Nutr Food Res , vol.52 , pp. 507-526
    • Ramos, S.1
  • 30
    • 0347997608 scopus 로고    scopus 로고
    • MAPK signal pathways in the regulation of cell proliferation in mammalian cells
    • Zhang W and Liu HT: MAPK signal pathways in the regulation of cell proliferation in mammalian cells. Cell Res 12: 9-18, 2002.
    • (2002) Cell Res , vol.12 , pp. 9-18
    • Zhang, W.1    Liu, H.T.2
  • 31
    • 0141502208 scopus 로고    scopus 로고
    • Downmodulation of ERK activity inhibits the proliferation and induces the apoptosis of primary acute myelogenous leukemia blasts
    • Lunghi P, Tabilio A, Dall'Aglio PP, Ridolo E, Carlo-Stella C, Pelicci PG and Bonati A: Downmodulation of ERK activity inhibits the proliferation and induces the apoptosis of primary acute myelogenous leukemia blasts. Leukemia 17: 1783-1793, 2003.
    • (2003) Leukemia , vol.17 , pp. 1783-1793
    • Lunghi, P.1    Tabilio, A.2    Dall'Aglio, P.P.3    Ridolo, E.4    Carlo-Stella, C.5    Pelicci, P.G.6    Bonati, A.7
  • 32
    • 4644261860 scopus 로고    scopus 로고
    • Blocking the Raf/MEK/ERK pathway sensitizes acute myelogenous leukemia cells to lovastatin-induced apoptosis
    • Wu J, Wong WW, Khosravi F, Minden MD and Penn LZ: Blocking the Raf/MEK/ERK pathway sensitizes acute myelogenous leukemia cells to lovastatin-induced apoptosis. Cancer Res 64: 6461-6468, 2004.
    • (2004) Cancer Res , vol.64 , pp. 6461-6468
    • Wu, J.1    Wong, W.W.2    Khosravi, F.3    Minden, M.D.4    Penn, L.Z.5
  • 33
    • 34247388477 scopus 로고    scopus 로고
    • Oridonin induced apoptosis through Akt and MAPKs signaling pathways in human osteosarcoma cells
    • Jin S, Shen JN, Wang J, Huang G and Zhou JG: Oridonin induced apoptosis through Akt and MAPKs signaling pathways in human osteosarcoma cells. Cancer Biol Ther 6: 261-268, 2007.
    • (2007) Cancer Biol Ther , vol.6 , pp. 261-268
    • Jin, S.1    Shen, J.N.2    Wang, J.3    Huang, G.4    Zhou, J.G.5
  • 34
    • 77956301155 scopus 로고    scopus 로고
    • Oridonin induces G2/M cell cycle arrest and apoptosis through MAPK and p53 signaling pathways in HepG2 cells
    • Wang H, Ye Y, Chui JH, Zhu GY, Li YW, Fong DW and Yu ZL: Oridonin induces G2/M cell cycle arrest and apoptosis through MAPK and p53 signaling pathways in HepG2 cells. Oncol Rep 24: 647-651, 2010.
    • (2010) Oncol Rep , vol.24 , pp. 647-651
    • Wang, H.1    Ye, Y.2    Chui, J.H.3    Zhu, G.Y.4    Li, Y.W.5    Fong, D.W.6    Yu, Z.L.7
  • 36
    • 33750412872 scopus 로고    scopus 로고
    • Surviving cell death through epidermal growth factor (EGF) signal transduction pathways: Implications for cancer therapy
    • Henson ES and Gibson SB: Surviving cell death through epidermal growth factor (EGF) signal transduction pathways: Implications for cancer therapy. Cell Signal 18: 2089-2097, 2006.
    • (2006) Cell Signal , vol.18 , pp. 2089-2097
    • Henson, E.S.1    Gibson, S.B.2
  • 37
    • 84892404410 scopus 로고    scopus 로고
    • Oridonin induces apoptosis in SW1990 pancreatic cancer cells via p53-and caspase-dependent induction of p38 MAPK
    • Bu HQ, Liu DL, Wei WT, Chen L, Huang H, Li Y and Cui JH: Oridonin induces apoptosis in SW1990 pancreatic cancer cells via p53-and caspase-dependent induction of p38 MAPK. Oncol Rep 31: 975-982, 2014.
    • (2014) Oncol Rep , vol.31 , pp. 975-982
    • Bu, H.Q.1    Liu, D.L.2    Wei, W.T.3    Chen, L.4    Huang, H.5    Li, Y.6    Cui, J.H.7
  • 38
    • 77953611988 scopus 로고    scopus 로고
    • P38 MAPK and NF-kappaB pathways are involved in naphtho[1,2-b] furan-4,5-dione induced anti-proliferation and apoptosis of human hepatoma cells
    • Chiu CC, Chen JY, Lin KL, Huang CJ, Lee JC, Chen BH, Chen WY, Lo YH, Chen YL, Tseng CH, et al: p38 MAPK and NF-kappaB pathways are involved in naphtho[1,2-b] furan-4,5-dione induced anti-proliferation and apoptosis of human hepatoma cells. Cancer Lett 295: 92-99, 2010.
    • (2010) Cancer Lett , vol.295 , pp. 92-99
    • Chiu, C.C.1    Chen, J.Y.2    Lin, K.L.3    Huang, C.J.4    Lee, J.C.5    Chen, B.H.6    Chen, W.Y.7    Lo, Y.H.8    Chen, Y.L.9    Tseng, C.H.10


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