Hepatic expression of proteasome subunit alpha type-6 is upregulated during viral hepatitis and putatively regulates the expression of ISG15 ubiquitin-like modifier, a proviral host gene in hepatitis C virus infection

Journal of Viral Hepatitis

Volumn 23, Issue 5, 2016, Pages 375-386

  Broering, R ^a   Trippler, M ^a   Werner, M ^a   Real, C I ^a   Megger, D A ^b   Bracht, T ^b   Schweinsberg, V ^b   Sitek, B ^b   Eisenacher, M ^b   Meyer, H E ^b,c   Baba, H A ^a   Weber, F ^a   Hoffmann, A C ^a   Gerken, G ^a   Schlaak, J F ^a  

^a UNIVERSITY HOSPITAL ESSEN   (Germany)

^b RUHR UNIVERSITY BOCHUM   (Germany)

^c LEIBNIZ INSTITUT FÜR ANALYTISCHE WISSENSCHAFTEN ISAS E V   (Germany)

Author keywords

hepatitis C virus; host factors; interferon stimulated gene 15; proteasome; proteasome subunit alpha type 6

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; DIMETHYL SULFOXIDE; INTERFERON REGULATORY FACTOR 3; MESSENGER RNA; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOTRANSFERASE INHIBITOR; POLYINOSINIC POLYCYTIDYLIC ACID; PROTEASOME; PROTEASOME SUBUNIT ALPHA TYPE 6; PROTEIN KINASE B; PROTEIN KINASE B INHIBITOR; SMALL INTERFERING RNA; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 3; UNCLASSIFIED DRUG; CYTOKINE; ISG15 PROTEIN, HUMAN; PROTEOME; PSMA6 PROTEIN, HUMAN; UBIQUITIN;

ARTICLE; CONTROLLED STUDY; ENZYME SUBUNIT; GENE; GENE EXPRESSION REGULATION; GENE REPRESSION; GENE SILENCING; GENOTYPE; HEPATITIS C; HEPATITIS C VIRUS; HUMAN; HUMAN CELL; HUMAN TISSUE; INTERFERON STIMULATED GENE 15; LIVER CELL; MAJOR CLINICAL STUDY; OBSERVATIONAL STUDY; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEOMICS; PROVIRUS; REPLICON; SIGNAL TRANSDUCTION; TRANSCRIPTOMICS; UPREGULATION; VIRUS CELL INTERACTION; VIRUS LOAD; ADULT; BIOPSY; BIOSYNTHESIS; CELL CULTURE; FEMALE; GENE EXPRESSION; GENE EXPRESSION PROFILING; MALE; MIDDLE AGED; PATHOLOGY; PHYSIOLOGY;

ADULT; BIOPSY; CELLS, CULTURED; CYTOKINES; FEMALE; GENE EXPRESSION; GENE EXPRESSION PROFILING; HEPATITIS C; HEPATOCYTES; HUMANS; MALE; MIDDLE AGED; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEOME; UBIQUITINS;

EID: 84956893804     PISSN: 13520504     EISSN: 13652893     Source Type: Journal    
DOI: 10.1111/jvh.12508     Document Type: Article

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