Controlled transdermal iontophoresis for poly-pharmacotherapy: Simultaneous delivery of granisetron, metoclopramide and dexamethasone sodium phosphate in vitro and in vivo

European Journal of Pharmaceutical Sciences

Volumn 85, Issue , 2016, Pages 31-38

  Cázares Delgadillo, Jennyfer ^a   Ganem Rondero, Adriana ^b   Merino, Virginia ^c   Kalia, Yogeshvar N ^a  

^a UNIVERSITY OF GENEVA   (Switzerland)

^b UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

^c UNIVERSITY OF VALENCIA   (Spain)

Author keywords

Antiemetics; Iontophoresis; Pharmacokinetics; Poly pharmacotherapy; Transdermal

Indexed keywords

DEXAMETHASONE SODIUM PHOSPHATE; GRANISETRON; METOCLOPRAMIDE; DEXAMETHASONE; DEXAMETHASONE 21-PHOSPHATE;

ABSORPTION RATE CONSTANT; ANIMAL EXPERIMENT; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; CAPILLARY ZONE ELECTROPHORESIS; CONCENTRATION (PARAMETERS); CONTROLLED RELEASE FORMULATION; CONTROLLED STUDY; CURRENT DENSITY; DERMIS; DRUG BLOOD LEVEL; DRUG DELIVERY SYSTEM; DRUG HALF LIFE; DRUG HYDROLYSIS; DRUG PENETRATION; DRUG STRUCTURE; DRUG TRANSPORT; ELECTRICITY; ELECTROOSMOSIS; ELIMINATION RATE CONSTANT; ENZYME ACTIVITY; HYDROPHOBICITY; IN VITRO STUDY; IN VIVO STUDY; IONTOPHORESIS; MALE; MOLECULAR INTERACTION; MOLECULAR WEIGHT; NONHUMAN; PHYSICAL CHEMISTRY; POLYPHARMACY; PRIORITY JOURNAL; RAT; RATE CONSTANT; SKIN FUNCTION; STEADY STATE; SURFACE AREA; TRANSDERMAL IONTOPHORETIC DELIVERY; VOLUME OF DISTRIBUTION; ANALOGS AND DERIVATIVES; ANIMAL; CUTANEOUS DRUG ADMINISTRATION; HYDROLYSIS; METABOLISM; PIG; PROCEDURES; SKIN; WISTAR RAT;

ADMINISTRATION, CUTANEOUS; ANIMALS; DEXAMETHASONE; GRANISETRON; HYDROLYSIS; IONTOPHORESIS; MALE; METOCLOPRAMIDE; POLYPHARMACY; RATS; RATS, WISTAR; SKIN; SWINE;

EID: 84956891195     PISSN: 09280987     EISSN: 18790720     Source Type: Journal    
DOI: 10.1016/j.ejps.2016.01.027     Document Type: Article

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