Kindlin-2 cooperates with talin to activate integrins and induces cell spreading by directly binding paxillin

eLife

Volumn 5, Issue JANUARY2016, 2016, Pages

  Theodosiou, Marina ^a   Widmaier, Moritz ^a   Böttcher, Ralph T ^a   Rognoni, Emanuel ^a   Veelders, Maik ^a   Bharadwaj, Mitasha ^b   Lambacher, Armin ^a   Austen, Katharina ^a   Müller, Daniel J ^b   Zent, Roy ^c,d   Fässler, Reinhard ^a  

^a MAX PLANCK INSTITUTE OF BIOCHEMISTRY   (Germany)

^b ETH ZURICH   (Switzerland)

^c VANDERBILT UNIVERSITY   (United States)

^d VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA1 INTEGRIN; COLLAGEN TYPE 1; COMPLEMENTARY DNA; FIBRONECTIN; FOCAL ADHESION KINASE; INTEGRIN LINKED KINASE; KINDLIN 2; MANGANESE; PAXILLIN; POLYLYSINE; PROTEIN; RECOMBINANT PROTEIN; TALIN; UNCLASSIFIED DRUG; CYTOSKELETON PROTEIN; KINDLIN-2 PROTEIN, MOUSE; MUSCLE PROTEIN; PROTEIN BINDING; TALIN PROTEIN, MOUSE;

ANIMAL CELL; ARTICLE; ATOMIC FORCE MICROSCOPY; CELL ADHESION ASSAY; CELL SPREADING; CELL STRUCTURE; CLUSTER ANALYSIS; FIBROBLAST; FLOW CYTOMETRY; FOCAL ADHESION; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; LAMELLIPODIUM; MOUSE; NONHUMAN; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN PURIFICATION; REAL TIME POLYMERASE CHAIN REACTION; RNA EXTRACTION; ANIMAL; CELL ADHESION; CELL LINE; CELL MOTION; METABOLISM; PHYSIOLOGY;

ANIMALS; ANTIGENS, CD29; CELL ADHESION; CELL LINE; CELL MOVEMENT; CYTOSKELETAL PROTEINS; FIBROBLASTS; FOCAL ADHESION PROTEIN-TYROSINE KINASES; MANGANESE; MICE; MUSCLE PROTEINS; PAXILLIN; PROTEIN BINDING; TALIN;

EID: 84956877791     PISSN: None     EISSN: 2050084X     Source Type: Journal    
DOI: 10.7554/eLife.10130     Document Type: Article

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