The Chlamydia effector TarP mimics the mammalian leucine-aspartic acid motif of paxillin to subvert the focal adhesion kinase during invasion

Journal of Biological Chemistry

Volumn 289, Issue 44, 2014, Pages 30426-30442

  Thwaites, Tristan ^a,b   Nogueira, Ana T ^a,b   Campeotto, Ivan ^a   Silva, Ana P ^b   Grieshaber, Scott S ^c   Carabeo, Rey A ^a,b  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF ABERDEEN   (United Kingdom)

^c UNIVERSITY OF FLORIDA COLLEGE OF DENTISTRY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADHESION; AMINO ACIDS; BINS; CELL MEMBRANES; CYTOLOGY; ENZYMES; MAMMALS; PATHOGENS; SIGNAL TRANSDUCTION;

BACTERIAL ADHESION; BACTERIAL PATHOGENS; FOCAL ADHESION KINASE; FUNCTIONAL RELEVANCE; INTRACELLULAR PATHOGENS; QUANTITATIVE IMAGING; SIGNAL TRANSDUCTION PATHWAYS; SIGNALING PATHWAYS;

PROTEINS;

ACTIN RELATED PROTEIN 2-3 COMPLEX; ASPARTIC ACID; BACTERIAL PROTEIN; F ACTIN; FOCAL ADHESION KINASE; LEUCINE; PAXILLIN; PROTEIN CDC42; PROTEIN TARP; UNCLASSIFIED DRUG; ACTIN; FOCAL ADHESION KINASE 1; PROTEIN BINDING; VIRULENCE FACTOR;

ACTIN FILAMENT; ANIMAL CELL; ARTICLE; BACTERIAL VIRULENCE; CELL MEMBRANE; CHLAMYDIA; CHLAMYDIA CAVIAE; CONTROLLED STUDY; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PROTEIN ASSEMBLY; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEIN LOCALIZATION; PROTEIN MOTIF; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; AMINO ACID SEQUENCE; ANIMAL; BACTERIUM ADHERENCE; CHEMISTRY; CHLAMYDIA TRACHOMATIS; CHLOROCEBUS AETHIOPS; COS 1 CELL LINE; ENZYMOLOGY; HOST PATHOGEN INTERACTION; METABOLISM; MICROBIOLOGY; MOLECULAR GENETICS; MOLECULAR MIMICRY; NUCLEOTIDE SEQUENCE; PHOSPHORYLATION; PHYSIOLOGY; PROTEIN PROCESSING; PROTEIN TRANSPORT;

ACTIN-RELATED PROTEIN 2-3 COMPLEX; ACTINS; AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ANIMALS; BACTERIAL ADHESION; BACTERIAL PROTEINS; CDC42 GTP-BINDING PROTEIN; CELL MEMBRANE; CERCOPITHECUS AETHIOPS; CHLAMYDIA TRACHOMATIS; CONSERVED SEQUENCE; COS CELLS; FOCAL ADHESION KINASE 1; HOST-PATHOGEN INTERACTIONS; HUMANS; MOLECULAR MIMICRY; MOLECULAR SEQUENCE DATA; PAXILLIN; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN TRANSPORT; VIRULENCE FACTORS;

EID: 84908592806     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.604876     Document Type: Article

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