Covalent Chemical Ligation Strategy for Mono- and Polyclonal Immunoglobulins at Their Nucleotide Binding Sites

Bioconjugate Chemistry

Volumn 27, Issue 1, 2016, Pages 159-169

  Lac, Diana ^a   Feng, Chun ^a   Bhardwaj, Gaurav ^a   Le, Huong ^a   Tran, Jimmy ^a   Xing, Li ^b   Fung, Gabriel ^a   Liu, Ruiwu ^a   Cheng, Holland ^b   Lam, Kit S ^a,b,c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BINDING SITES; NUCLEOTIDES;

ANTIBODY-DRUG CONJUGATES; BINDING POCKETS; CHEMICAL LIGATION; DERIVATIZATIONS; NUCLEOTIDE BINDING; NUCLEOTIDE-BINDING SITES; PEPTIDE LIBRARY; POLYCLONAL; SITE-SPECIFIC; THERAPEUTIC ANTIBODIES;

ANTIBODIES;

ANTIBODY CONJUGATE; BEVACIZUMAB; CETUXIMAB; IMMUNOGLOBULIN; INDOLE; LYSINE; MONOCLONAL ANTIBODY; PARAPROTEIN; POLYCLONAL ANTIBODY; POLYCLONAL IMMUNOGLOBULIN; RITUXIMAB; STREPTAVIDIN; TRASTUZUMAB; UNCLASSIFIED DRUG; 2 (4 HYDROXYPHENYLAZO)BENZOIC ACID; AZO COMPOUND; BIOTIN; BISPECIFIC ANTIBODY; CROSS LINKING REAGENT; IMMUNOGLOBULIN F(AB) FRAGMENT; INDOLE DERIVATIVE; INDOLEBUTYRIC ACID; NUCLEOTIDE; OLIGOPEPTIDE; PEPTIDE; PEPTIDE LIBRARY; VEDOTIN;

ARTICLE; CONTROLLED STUDY; DERIVATIZATION; NEOPLASM; NUCLEOTIDE BINDING SITE; PEPTIDE LIBRARY; BINDING SITE; CHEMISTRY; HUMAN; IMMUNOLOGY; METABOLISM;

ANTIBODIES, BISPECIFIC; ANTIBODIES, MONOCLONAL; AZO COMPOUNDS; BINDING SITES; BIOTIN; CROSS-LINKING REAGENTS; HUMANS; IMMUNOCONJUGATES; IMMUNOGLOBULIN FAB FRAGMENTS; IMMUNOGLOBULINS; INDOLES; NUCLEOTIDES; OLIGOPEPTIDES; PEPTIDE LIBRARY; PEPTIDES; TRASTUZUMAB;

EID: 84956839369     PISSN: 10431802     EISSN: 15204812     Source Type: Journal    
DOI: 10.1021/acs.bioconjchem.5b00574     Document Type: Article

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