High glucose induces rat mesangial cells proliferation and MCP-1 expression via ROS-mediated activation of NF-κB pathway, which is inhibited by eleutheroside E

Journal of Receptors and Signal Transduction

Volumn 36, Issue 2, 2016, Pages 152-157

  Yang, Xiuqin ^a   Wang, Yangang ^b   Gao, Guanqi ^a  

^a LINYI PEOPLE'S HOSPITAL   (China)

^b QINGDAO UNIVERSITY   (China)

Author keywords

Cell proliferation; eleutheroside E; high glucose; mesangial cells; monocyte chemoattractant protein 1; nuclear factor kappa B; reactive oxygen species

Indexed keywords

GLUCOSE; I KAPPA B ALPHA; I KAPPA B KINASE BETA; MONOCYTE CHEMOTACTIC PROTEIN 1; PROTEIN P47; REACTIVE OXYGEN METABOLITE; RECEPTOR ACTIVATOR OF NUCLEAR FACTOR KAPPA B; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SITOGLUSIDE; CCL2 PROTEIN, RAT; ELEUTHEROSIDE E; GLUCOSIDE; I KAPPA B; I KAPPA B KINASE ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIGNAN; TRANSCRIPTION FACTOR RELA;

ARTICLE; CELL PROLIFERATION; DOSE RESPONSE; ELISA KIT; MESANGIUM CELL; MOUSE; MTT ASSAY; NONHUMAN; PROTEIN EXPRESSION; ANIMAL; BIOSYNTHESIS; DIABETIC NEPHROPATHIES; DISEASE MODEL; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; HUMAN; METABOLISM; PATHOLOGY; RAT; SIGNAL TRANSDUCTION;

ANIMALS; CELL PROLIFERATION; CHEMOKINE CCL2; DIABETIC NEPHROPATHIES; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION; GLUCOSE; GLUCOSIDES; HUMANS; I-KAPPA B PROTEINS; LIGNANS; MESANGIAL CELLS; NADPH OXIDASE; NF-KAPPA B; NF-KAPPAB INHIBITOR ALPHA; RATS; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTOR RELA;

EID: 84956825100     PISSN: 10799893     EISSN: 15324281     Source Type: Journal    
DOI: 10.3109/10799893.2015.1061002     Document Type: Article

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