Increased oxidative metabolism following hypoxia in the type 2 diabetic heart, despite normal hypoxia signalling and metabolic adaptation

Journal of Physiology

Volumn 594, Issue 2, 2016, Pages 307-320

  Mansor, Latt S ^a   Mehta, Keshavi ^a   Aksentijevic, Dunja ^b   Carr, Carolyn A ^a   Lund, Trine ^c   Cole, Mark A ^d   Page, Lydia Le ^a   Sousa Fialho, Maria da Luz ^a   Shattock, Michael J ^b   Aasum, Ellen ^c   Clarke, Kieran ^a   Tyler, Damian J ^a   Heather, Lisa C ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b KING'S COLLEGE LONDON   (United Kingdom)

^c UNIVERSITY OF TROMSØ   (Norway)

^d UNIVERSITY OF NOTTINGHAM   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

FATTY ACID; GLYCOGEN; HYPOXIA INDUCIBLE FACTOR; LACTIC ACID; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; OXYGEN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA;

ADAPTATION; AEROBIC METABOLISM; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FATTY ACID OXIDATION; GLUCOSE METABOLISM; GLYCOLYSIS; HEART CONTRACTION; HEART FUNCTION; HEART MUSCLE METABOLISM; HYPOXIA; LIPID METABOLISM; METABOLIC REGULATION; MITOCHONDRIAL RESPIRATION; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PRIORITY JOURNAL; RAT; UPREGULATION; ANIMAL; CARDIAC MUSCLE; CELL HYPOXIA; DIABETIC CARDIOMYOPATHY; GENETICS; MALE; METABOLISM; MUSCLE MITOCHONDRION; OXIDATIVE STRESS; SIGNAL TRANSDUCTION; WISTAR RAT;

ADAPTATION, PHYSIOLOGICAL; ANIMALS; CELL HYPOXIA; DIABETES MELLITUS, TYPE 2; DIABETIC CARDIOMYOPATHIES; GLYCOGEN; GLYCOLYSIS; LACTIC ACID; MALE; MITOCHONDRIA, MUSCLE; MYOCARDIUM; OXIDATIVE STRESS; OXYGEN; PPAR GAMMA; RATS; RATS, WISTAR; SIGNAL TRANSDUCTION;

EID: 84956734982     PISSN: 00223751     EISSN: 14697793     Source Type: Journal    
DOI: 10.1113/JP271242     Document Type: Article

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