Prediction of Site of Metabolism in Humans: Case Studies of Cytochromes P450 2C9, 2D6, and 3A4

Pharmacokinetic Profiling in Drug Research

Volumn , Issue , 2007, Pages 367-379

  Cruciani, Gabriele ^a   Vianello, Riccardo ^b   Zamora, Ismael ^c  

^a UNIVERSITY OF PERUGIA   (Italy)

^b Molecular Discovery Limited   (United Kingdom)

^c Fransesc Cabanes i Alibau   (Spain)

Author keywords

Catalysts of drug metabolism; Computational strategies; Metabolism in humans; Superfamily of cytochrome P450 (CYP) enzymes

Indexed keywords

PHYSIOLOGY;

CASE-STUDIES; COMPUTATIONAL STRATEGY; CYTOCHROME P450; CYTOCHROMES P450; DRUG METABOLISMS;

METABOLISM;

EID: 84956683984     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9783906390468.ch21     Document Type: Chapter

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