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Volumn 387, Issue , 1996, Pages 361-369

Electronic models for cytochrome P450 oxidations

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450;

EID: 0029741968     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4757-9480-9_44     Document Type: Conference Paper
Times cited : (21)

References (25)
  • 1
    • 0345087856 scopus 로고
    • Enzymology of Extrahepatic Cytochromes P450
    • F.P. Guengerich (ed.), Boca Raton: CRC Press
    • Masters, B.S.S., Muerhoff, A.S., and Okita, R.T., 1987, Enzymology of Extrahepatic Cytochromes P450. In: F.P. Guengerich (ed.), Mammalian Cytochromes P-450, pp. 107-131, Boca Raton: CRC Press.
    • (1987) Mammalian Cytochromes P-450 , pp. 107-131
    • Masters, B.S.S.1    Muerhoff, A.S.2    Okita, R.T.3
  • 2
    • 0002270104 scopus 로고
    • Cytochrome P-450 Enzymes in Sterol Biosynthesis and Metabolism
    • P.R. Ortiz de Montellano (ed.), New York: Plenum Press
    • Jefcoate, C., 1986, Cytochrome P-450 Enzymes in Sterol Biosynthesis and Metabolism. In: P.R. Ortiz de Montellano (ed.), Cytochrome P-450, pp. 387-428, New York: Plenum Press.
    • (1986) Cytochrome P-450 , pp. 387-428
    • Jefcoate, C.1
  • 3
    • 0025067462 scopus 로고
    • Molecular genetics of the P-450 superfamily
    • Gonzalez, F.J., 1990, Molecular genetics of the P-450 superfamily. Pharmacol. Ther., 45: 1-38.
    • (1990) Pharmacol. Ther. , vol.45 , pp. 1-38
    • Gonzalez, F.J.1
  • 6
    • 0024451771 scopus 로고
    • Theory for the observed isotope effects from enzymatic systems that form multiple products via branched reaction pathways: Cytochrome P-450
    • Korzekwa, K.R., Trager, W.F., and Gillette, J.R., 1989, Theory for the observed isotope effects from enzymatic systems that form multiple products via branched reaction pathways: cytochrome P-450. Biochemistry, 28: 9012-9018.
    • (1989) Biochemistry , vol.28 , pp. 9012-9018
    • Korzekwa, K.R.1    Trager, W.F.2    Gillette, J.R.3
  • 7
    • 0000497670 scopus 로고
    • Isotopically sensitive branching and its effect on the observed intramolecular isotope effects in cytochrome P-450 catalyzed reactions: A new method for the estimation of intrinsic isotope effects
    • Jones, J.P., Korzekwa, K.R., Rettie, A.E., and Trager, W.F., 1986, Isotopically sensitive branching and its effect on the observed intramolecular isotope effects in cytochrome P-450 catalyzed reactions: a new method for the estimation of intrinsic isotope effects. J. Am. Chem. Soc., 108: 7074-7078.
    • (1986) J. Am. Chem. Soc. , vol.108 , pp. 7074-7078
    • Jones, J.P.1    Korzekwa, K.R.2    Rettie, A.E.3    Trager, W.F.4
  • 8
    • 0018817225 scopus 로고
    • Oxygen activation by cytochrome P-450
    • White, R.E. and Coon, M.J., 1980, Oxygen activation by cytochrome P-450. Annu. Rev. Biochem., 49: 315-356.
    • (1980) Annu. Rev. Biochem. , vol.49 , pp. 315-356
    • White, R.E.1    Coon, M.J.2
  • 9
    • 0027366973 scopus 로고
    • Use of aromatase (CYP19) metabolite ratios to characterize electron transfer from NADPH-cytochrome P450 reductase
    • Grogan, J., Shou, M., Zhou, D., Chen, S., and Korzekwa, K.R., 1993, Use of aromatase (CYP19) metabolite ratios to characterize electron transfer from NADPH-cytochrome P450 reductase. Biochemistry, 32: 12007-12012.
    • (1993) Biochemistry , vol.32 , pp. 12007-12012
    • Grogan, J.1    Shou, M.2    Zhou, D.3    Chen, S.4    Korzekwa, K.R.5
  • 10
    • 0000701892 scopus 로고
    • The Oxidation of Drugs by Liver Microsomes: On the Role of TPNH and Oxygen
    • Gillette, J.R., Brodie, B.B., and La Du, B.N., 1957, The Oxidation of Drugs by Liver Microsomes: On the Role of TPNH and Oxygen. J. Pharmacol. Exp. Ther., 119: 532-540.
    • (1957) J. Pharmacol. Exp. Ther. , vol.119 , pp. 532-540
    • Gillette, J.R.1    Brodie, B.B.2    La Du, B.N.3
  • 11
    • 0017409578 scopus 로고
    • Hydrogen Peroxide Formation and Stoichiometry of Hydroxylation Reactions Catalyzed by Highly Purified Liver Microsomal Cytochrome P-450
    • Nordblom, G.D. and Coon, M.J. 1982, Hydrogen Peroxide Formation and Stoichiometry of Hydroxylation Reactions Catalyzed by Highly Purified Liver Microsomal Cytochrome P-450. Arch. Biochem. Biophys., 180: 343-347,.
    • (1982) Arch. Biochem. Biophys. , vol.180 , pp. 343-347
    • Nordblom, G.D.1    Coon, M.J.2
  • 12
    • 0020465448 scopus 로고
    • Catalytic Activity of Cytochrome P-450 Isozyme 3a Isolated from Liver Microsomes of Ethanol-treated Rabbits
    • Morgan, E.T., Koop, D.R., and Coon, M.J., 1982, Catalytic Activity of Cytochrome P-450 Isozyme 3a Isolated from Liver Microsomes of Ethanol-treated Rabbits. J. Biol. Chem., 257: 13591-13597.
    • (1982) J. Biol. Chem. , vol.257 , pp. 13591-13597
    • Morgan, E.T.1    Koop, D.R.2    Coon, M.J.3
  • 13
    • 0021138883 scopus 로고
    • On the Stoichiometry of the Oxidase and Monooxygenase Reactions Catalyzed by Liver Microsomal Cytochrome P-450
    • Gorsky, L.D., Koop, D.R., and Coon, M.J., 1982, On the Stoichiometry of the Oxidase and Monooxygenase Reactions Catalyzed by Liver Microsomal Cytochrome P-450. J. Biol. Chem., 259: 6812-6817.
    • (1982) J. Biol. Chem. , vol.259 , pp. 6812-6817
    • Gorsky, L.D.1    Koop, D.R.2    Coon, M.J.3
  • 14
    • 37049137124 scopus 로고
    • The Bronsted relation - Recent developments
    • Kresge, A.J., 1973, The Bronsted relation - recent developments. Chem. Soc. Rev., 2: 475-503.
    • (1973) Chem. Soc. Rev. , vol.2 , pp. 475-503
    • Kresge, A.J.1
  • 15
    • 0000385707 scopus 로고
    • The Separation of the Intramolecular Isotope Effect for the Cytochrome P-450 Catalyzed Hydroxylation of n-Octane into its Primary and Secondary Components
    • Jones, J.P. and Trager, W.F., 1987, The Separation of the Intramolecular Isotope Effect for the Cytochrome P-450 Catalyzed Hydroxylation of n-Octane into its Primary and Secondary Components. J. Am. Chem. Soc., 109: 2171-2173.
    • (1987) J. Am. Chem. Soc. , vol.109 , pp. 2171-2173
    • Jones, J.P.1    Trager, W.F.2
  • 16
    • 0025216839 scopus 로고
    • Intrinsic isotope effects suggest that the reaction coordinate symmetry for the cytochrome P-450 catalyzed hydroxylation of octane is isozyme independent
    • Jones, J.P., Rettie, A.E., and Trager, W.F., 1990, Intrinsic isotope effects suggest that the reaction coordinate symmetry for the cytochrome P-450 catalyzed hydroxylation of octane is isozyme independent. J. Med. Chem., 33: 1242-1246.
    • (1990) J. Med. Chem. , vol.33 , pp. 1242-1246
    • Jones, J.P.1    Rettie, A.E.2    Trager, W.F.3
  • 17
    • 0025150366 scopus 로고
    • Theoretical studies on cytochrome P-450 mediated hydroxylation: A predictive model for hydrogen atom abstractions
    • Korzekwa, K.R., Jones, J.P., and Gillette, J.R. Theoretical studies on cytochrome P-450 mediated hydroxylation: a predictive model for hydrogen atom abstractions. J. Am. Chem. Soc., 112: 7042-7046, 1990.
    • (1990) J. Am. Chem. Soc. , vol.112 , pp. 7042-7046
    • Korzekwa, K.R.1    Jones, J.P.2    Gillette, J.R.3
  • 18
    • 0026779457 scopus 로고
    • Modeling Cyanide Release from Nitriles: Prediction of Cytochrome P450 Mediated Acute Nitrile Toxicity
    • Grogan, J., DeVito, S.C., Pearlman, R.S., and Korzekwa, K.R., 1992, Modeling Cyanide Release from Nitriles: Prediction of Cytochrome P450 Mediated Acute Nitrile Toxicity. Chem. Res. Toxicol., 5: 548-552.
    • (1992) Chem. Res. Toxicol. , vol.5 , pp. 548-552
    • Grogan, J.1    DeVito, S.C.2    Pearlman, R.S.3    Korzekwa, K.R.4
  • 19
    • 0021262884 scopus 로고
    • Studies on the mechanism of acute toxicity of nitriles in mice
    • Tanii, H. and Hashimoto, K., 1984, Studies on the mechanism of acute toxicity of nitriles in mice. Arch. Toxicol., 55: 47-54.
    • (1984) Arch. Toxicol. , vol.55 , pp. 47-54
    • Tanii, H.1    Hashimoto, K.2
  • 20
    • 0021847126 scopus 로고
    • Structure-acute toxicity relationship of dinitriles in mice
    • Tanii, H. and Hashimoto, K., 1985, Structure-acute toxicity relationship of dinitriles in mice. Arch. Toxicol., 57: 88-93.
    • (1985) Arch. Toxicol. , vol.57 , pp. 88-93
    • Tanii, H.1    Hashimoto, K.2
  • 21
    • 0022518374 scopus 로고
    • Active site mechanics of liver microsomal cytochrome P-450
    • White, R.E. and McCarthy, M.B., 1986, Active site mechanics of liver microsomal cytochrome P-450. Arch. Biochem. Biophys., 246: 19-32.
    • (1986) Arch. Biochem. Biophys. , vol.246 , pp. 19-32
    • White, R.E.1    McCarthy, M.B.2
  • 22
    • 9344237490 scopus 로고
    • Previous chapter, this issue
    • Anders, M.W., 1995, Previous chapter, this issue.
    • (1995)
    • Anders, M.W.1
  • 23
    • 0028947612 scopus 로고
    • Mechanism of oxidative amine dealkylation of substituted N,N-dimethylanilines by cytochrome P-450: Application of isotope effect profiles
    • in press
    • Karki, S.B., Dinnocenzo, J.P., Jones, J.P., and Korzekwa, K.R., 1995, Mechanism of oxidative amine dealkylation of substituted N,N-dimethylanilines by cytochrome P-450: Application of isotope effect profiles. J. Am. Chem. Soc.(in press).
    • (1995) J. Am. Chem. Soc.
    • Karki, S.B.1    Dinnocenzo, J.P.2    Jones, J.P.3    Korzekwa, K.R.4
  • 24
    • 0000906512 scopus 로고
    • Hydrocarbon bond dissociation energies
    • McMillen, D.F. and Golden, D.M., 1982, Hydrocarbon bond dissociation energies. Ann. Rev. Phys. Chem., 33: 493-532.
    • (1982) Ann. Rev. Phys. Chem. , vol.33 , pp. 493-532
    • McMillen, D.F.1    Golden, D.M.2
  • 25
    • 0025276611 scopus 로고
    • A Simulation of the Sulfur Attack in the Catalytic Pathway of Papain Using Molecular Mechanics and Semiemperical Quantum Mechanics
    • Arad, D., Langridge, R., and Kollman, P.A. A Simulation of the Sulfur Attack in the Catalytic Pathway of Papain Using Molecular Mechanics and Semiemperical Quantum Mechanics. J. Am. Chem. Soc., 112: 491-502, 1990.
    • (1990) J. Am. Chem. Soc. , vol.112 , pp. 491-502
    • Arad, D.1    Langridge, R.2    Kollman, P.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.