Cells activated for wound repair have the potential to direct collective invasion of an epithelium

Molecular Biology of the Cell

Volumn 27, Issue 3, 2016, Pages 451-465

  Bleaken, Brigid M ^a   Menko, A Sue ^a   Walker, Janice L ^a  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GELATINASE A; GELATINASE B; PROTEIN ZO1; VIMENTIN; AVIAN PROTEIN;

ANTERIOR LENS CAPSULE; ARTICLE; CELL INTERACTION; CELL INVASION; CELL MIGRATION; CONTROLLED STUDY; EPITHELIUM; EX VIVO STUDY; EXTRACELLULAR MATRIX; HUMAN; HUMAN CELL; INTERMEDIATE FILAMENT; LENS EPITHELIUM; MESENCHYME CELL; PRIORITY JOURNAL; THREE DIMENSIONAL IMAGING; TIME LAPSE IMAGING; TUMOR INVASION; WOUND HEALING; ANIMAL; CELL CULTURE; CELL CULTURE TECHNIQUE; CELL MOTION; CHICK EMBRYO; EPITHELIUM CELL; PHYSIOLOGY; TISSUE CULTURE TECHNIQUE;

ANIMALS; AVIAN PROTEINS; CELL CULTURE TECHNIQUES; CELL MOVEMENT; CELLS, CULTURED; CHICK EMBRYO; EPITHELIAL CELLS; EPITHELIUM; TISSUE CULTURE TECHNIQUES; VIMENTIN; WOUND HEALING;

EID: 84956636688     PISSN: 10591524     EISSN: 19394586     Source Type: Journal    
DOI: 10.1091/mbc.E15-09-0615     Document Type: Article

References (63)

1. Artym VV, Zhang Y, Seillier-Moiseiwitsch F, Yamada KM, Mueller SC (2006). Dynamic interactions of cortactin and membrane type 1 matrix metalloproteinase at invadopodia: defining the stages of invadopodia formation and function. Cancer Res 66, 3034-3043.
2. Ayala I, Baldassarre M, Giacchetti G, Caldieri G, Tete S, Luini A, Buccione R (2008). Multiple regulatory inputs converge on cortactin to control invadopodia biogenesis and extracellular matrix degradation. J Cell Sci 121, 369-378.
3. Balkwill F, Mantovani A (2001). Inflammation and cancer: back to Virchow? Lancet 357, 539-545.
4. Blouw B, Seals DF, Pass I, Diaz B, Courtneidge SA (2008). A role for the podosome/invadopodia scaffold protein Tks5 in tumor growth in vivo. Eur J Cell Biol 87, 555-567.
5. Bowden ET, Barth M, Thomas D, Glazer RI, Mueller SC (1999). An invasionrelated complex of cortactin, paxillin and PKCmu associates with invadopodia at sites of extracellular matrix degradation. Oncogene 18, 4440-4449.
6. Chang HY, Nuyten DS, Sneddon JB, Hastie T, Tibshirani R, Sorlie T, Dai H, He YD, van't Veer LJ, Bartelink H, et al. (2005). Robustness, scalability, and integration of a wound-response gene expression signature in predicting breast cancer survival. Proc Natl Acad Sci USA 102, 3738-3743.
7. Chang HY, Sneddon JB, Alizadeh AA, Sood R, West RB, Montgomery K, Chi JT, van de Rijn M, Botstein D, Brown PO (2004). Gene expression signature of fibroblast serum response predicts human cancer progression: similarities between tumors and wounds. PLoS Biol 2, E7.
8. Clark AG, Vignjevic DM (2015). Modes of cancer cell invasion and the role of the microenvironment. Curr Opin Cell Biol 36, 13-22.
9. Clark ES, Whigham AS, Yarbrough WG, Weaver AM (2007). Cortactin is an essential regulator of matrix metalloproteinase secretion and extracellular matrix degradation in invadopodia. Cancer Res 67, 4227-4235.
10. Condeelis J, Pollard JW (2006). Macrophages: obligate partners for tumor cell migration, invasion, and metastasis. Cell 124, 263-266.
11. Courtneidge SA, Azucena EF, Pass I, Seals DF, Tesfay L (2005). The SRC substrate Tks5, podosomes (invadopodia), and cancer cell invasion. Cold Spring Harb Symp Quant Biol 70, 167-171.
12. Coussens LM, Werb Z (2002). Inflammation and cancer. Nature 420, 860-867.
13. Crighton D, Olson MF (2011). Trailblazing LIM kinases take the lead in collective tumor cell invasion. Bioarchitecture 1, 5-8.
14. Crowther M, Brown NJ, Bishop ET, Lewis CE (2001). Microenvironmental influence on macrophage regulation of angiogenesis in wounds and malignant tumors. J Leukoc Biol 70, 478-490.
15. DeNardo DG, Barreto JB, Andreu P, Vasquez L, Tawfik D, Kolhatkar N, Coussens LM (2009). CD4(+) T cells regulate pulmonary metastasis of mammary carcinomas by enhancing protumor properties of macrophages. Cancer Cell 16, 91-102.
16. Destaing O, Petropoulos C, Albiges-Rizo C (2014). Coupling between actoadhesive machinery and ECM degradation in invadosomes. Cell Adh Migr 8, 256-262.
17. Di Martino J, Paysan L, Gest C, Lagree V, Juin A, Saltel F, Moreau V (2014). Cdc42 and Tks5: A minimal and universal molecular signature for functional invadosomes. Cell Adh Migr 8, 280-292.
18. Dushku N, Reid TW (1994). Immunohistochemical evidence that human pterygia originate from an invasion of vimentin-expressing altered limbal epithelial basal cells. Curr Eye Res 13, 473-481.
19. Dvorak HF (1986). Tumors: wounds that do not heal. Similarities between tumor stroma generation and wound healing. N Engl J Med 315, 1650-1659.
20. Friedl P, Locker J, Sahai E, Segall JE (2012). Classifying collective cancer cell invasion. Nat Cell Biol 14, 777-783.
21. Friedl P, Wolf K (2003). Tumour-cell invasion and migration: diversity and escape mechanisms. Nat Rev Cancer 3, 362-374.
22. Gaggioli C (2008). Collective invasion of carcinoma cells: when the fibroblasts take the lead. Cell Adh Migr 2, 45-47.
23. Gaggioli C, Hooper S, Hidalgo-Carcedo C, Grosse R, Marshall JF, Harrington K, Sahai E (2007). Fibroblast-led collective invasion of carcinoma cells with differing roles for RhoGTPases in leading and following cells. Nat Cell Biol 9, 1392-1400.
24. Gilles C, Polette M, Piette J, Delvigne AC, Thompson EW, Foidart JM, Birembaut P (1996). Vimentin expression in cervical carcinomas: Association with invasive and migratory potential. J Pathol 180, 175-180.
25. Gjorevski N, A SP, Varner VD, Nelson CM (2015). Dynamic tensile forces drive collective cell migration through three-dimensional extracellular matrices. Sci Rep 5, 11458.
26. Ivaska J, Pallari HM, Nevo J, Eriksson JE (2007). Novel functions of vimentin in cell adhesion, migration, and signaling. Exp Cell Res 313, 2050-2062.
27. Izawa I, Inagaki M (2006). Regulatory mechanisms and functions of intermediate filaments: A study using site- And phosphorylation state-specific antibodies. Cancer Sci 97, 167-174.
28. Kalluri R, Zeisberg M (2006). Fibroblasts in cancer. Nat Rev Cancer 6, 392-401.
29. Khalil AA, Friedl P (2010). Determinants of leader cells in collective cell migration. Integr Biol (Camb) 2, 568-574.
30. Leek RD, Harris AL (2002). Tumor-associated macrophages in breast cancer. J Mammary Gland Biol Neoplasia 7, 177-189.
31. Linder S (2007). The matrix corroded: podosomes and invadopodia in extracellular matrix degradation. Trends Cell Biol 17, 107-117.
32. Linder S (2009). Invadosomes at a glance. J Cell Sci 122, 3009-3013.
33. Linder S, Aepfelbacher M (2003). Podosomes: Adhesion hot-spots of invasive cells. Trends Cell Biol 13, 376-385.
34. Linder S, Wiesner C, Himmel M (2011). Degrading devices: invadosomes in proteolytic cell invasion. Annu Rev Cell Dev Biol 27, 185-211.
35. Lopez JI, Camenisch TD, Stevens MV, Sands BJ, McDonald J, Schroeder JA (2005). CD44 attenuates metastatic invasion during breast cancer progression. Cancer Res 65, 6755-6763.
36. Menko AS, Bleaken BM, Libowitz AA, Zhang L, Stepp MA, Walker JL (2014). A central role for vimentin in regulating repair function during healing of the lens epithelium. Mol Biol Cell 25, 776-790.
37. Misra S, Hascall VC, Markwald RR, Ghatak S (2015). Interactions between hyaluronan and its receptors (CD44, RHAMM) regulate the activities of inflammation and cancer. Front Immunol 6, 201.
38. Olson MF (2010). Follow the leader: LIM kinases pave the way for collective tumor cell invasion. Cell Cycle 9, 4417-4418.
39. Orimo A, Weinberg RA (2006). Stromal fibroblasts in cancer: A novel tumorpromoting cell type. Cell Cycle 5, 1597-1601.
40. Pedersen TX, Leethanakul C, Patel V, Mitola D, Lund LR, Dano K, Johnsen M, Gutkind JS, Bugge TH (2003). Laser capture microdissection-based in vivo genomic profiling of wound keratinocytes identifies similarities and differences to squamous cell carcinoma. Oncogene 22, 3964-3976.
41. Pulkoski-Gross AE (2015). Historical perspective of matrix metalloproteases. Front Biosci (School Ed) 7, 125-149.
42. Radisky DC (2007). Leading the charge. Nat Cell Biol 9, 1341-1342.
43. Riss J, Khanna C, Koo S, Chandramouli GV, Yang HH, Hu Y, Kleiner DE, Rosenwald A, Schaefer CF, Ben-Sasson SA, et al. (2006). Cancers as wounds that do not heal: differences and similarities between renal regeneration/repair and renal cell carcinoma. Cancer Res 66, 7216-7224.
44. Ronnov-Jessen L, Petersen OW, Bissell MJ (1996). Cellular changes involved in conversion of normal to malignant breast: importance of the stromal reaction. Physiol Rev 76, 69-125.
45. Rybinski B, Franco-Barraza J, Cukierman E (2014). The wound healing, chronic fibrosis, and cancer progression triad. Physiol Genomics 46, 223-244.
46. Saltel F, Daubon T, Juin A, Ganuza IE, Veillat V, Genot E (2011). Invadosomes: intriguing structures with promise. Eur J Cell Biol 90, 100-107.
47. Schaafsma HE, Van Der Velden LA, Manni JJ, Peters H, Link M, Rutter DJ, Ramaekers FC (1993). Increased expression of cytokeratins 8, 18 and vimentin in the invasion front of mucosal squamous cell carcinoma. J Pathol 170, 77-86.
48. Schafer M, Werner S (2008). Cancer as an overhealing wound: An old hypothesis revisited. Nat Rev Mol Cell Biol 9, 628-638.
49. Schoumacher M, Goldman RD, Louvard D, Vignjevic DM (2010). Actin, microtubules, and vimentin intermediate filaments cooperate for elongation of invadopodia. J Cell Biol 189, 541-556.
50. Scott RW, Hooper S, Crighton D, Li A, Konig I, Munro J, Trivier E, Wickman G, Morin P, Croft DR, et al. (2010). LIM kinases are required for invasive path generation by tumor and tumor-associated stromal cells. J Cell Biol 191, 169-185.
51. Shimoda M, Mellody KT, Orimo A (2010). Carcinoma-associated fibroblasts are a rate-limiting determinant for tumour progression. Semin Cell Dev Biol 21, 19-25.
52. Sihag RK, Inagaki M, Yamaguchi T, Shea TB, Pant HC (2007). Role of phosphorylation on the structural dynamics and function of types III and IV intermediate filaments. Exp Cell Res 313, 2098-2109.
53. Singh S, Sadacharan S, Su S, Belldegrun A, Persad S, Singh G (2003). Overexpression of vimentin: role in the invasive phenotype in an androgenindependent model of prostate cancer. Cancer Res 63, 2306-2311.
54. Snider NT, Omary MB (2014). Post-translational modifications of intermediate filament proteins: mechanisms and functions. Nat Rev Mol Cell Biol 15, 163-177.
55. Sutoh Yoneyama M, Hatakeyama S, Habuchi T, Inoue T, Nakamura T, Funyu T, Wiche G, Ohyama C, Tsuboi S (2014). Vimentin intermediate filament and plectin provide a scaffold for invadopodia, facilitating cancer cell invasion and extravasation for metastasis. Eur J Cell Biol 93, 157-169.
56. Thomas L, Byers HR, Vink J, Stamenkovic I (1992). CD44H regulates tumor cell migration on hyaluronate-coated substrate. J Cell Biol 118, 971-977.
57. Thompson EW, Paik S, Brunner N, Sommers CL, Zugmaier G, Clarke R, Shima TB, Torri J, Donahue S, Lippman ME, et al. (1992). Association of increased basement membrane invasiveness with absence of estrogen receptor and expression of vimentin in human breast cancer cell lines. J Cell Physiol 150, 534-544.
58. Walker JL, Bleaken BM, Wolff IM, Menko AS (2015). Establishment of a clinically relevant ex vivo mock cataract surgery model for investigating epithelial wound repair in a native microenvironment. J Vis Exp 2015, e52886.
59. Walker JL, Menko AS (1999). alpha6 Integrin is regulated with lens cell differentiation by linkage to the cytoskeleton and isoform switching. Dev Biol 210, 497-511.
60. Walker JL, Wolff IM, Zhang L, Menko AS (2007). Activation of SRC kinases signals induction of posterior capsule opacification. Invest Ophthalmol Visual Sci 48, 2214-2223.
61. Walker JL, Zhai N, Zhang L, Bleaken BM, Wolff I, Gerhart J, George- Weinstein M, Menko AS (2010). Unique precursors for the mesenchymal cells involved in injury response and fibrosis. Proc Natl Acad Sci USA 107, 13730-13735.
62. Wei J, Xu G, Wu M, Zhang Y, Li Q, Liu P, Zhu T, Song A, Zhao L, Han Z, et al. (2008). Overexpression of vimentin contributes to prostate cancer invasion and metastasis via src regulation. Anticancer Res 28, 327-334.
63. Wolf K, Wu YI, Liu Y, Geiger J, Tam E, Overall C, Stack MS, Friedl P (2007). Multi-step pericellular proteolysis controls the transition from individual to collective cancer cell invasion. Nat Cell Biol 9, 893-904.