Unique precursors for the mesenchymal cells involved in injury response and fibrosis

Proceedings of the National Academy of Sciences of the United States of America

Volumn 107, Issue 31, 2010, Pages 13730-13735

  Walker, Janice L ^a   Zhai, Ni ^a   Zhang, Liping ^a   Bleaken, Brigid M ^a   Wolff, Iris ^a   Gerhart, Jacquelyn ^b   George Weinstein, Mindy ^b   Menko, A Sue ^a  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

^b LANKENAU INSTITUTE FOR MEDICAL RESEARCH   (United States)

Author keywords

Lens; Migration; Myofibroblast; Posterior capsule opacification; Wound healing

Indexed keywords

MEMBRANE ANTIGEN; MESSENGER RNA; TRANSCRIPTION FACTOR; MYOD PROTEIN;

ANIMAL TISSUE; ARTICLE; CATARACT EXTRACTION; CELL FUNCTION; CELL MIGRATION; CHICKEN; EMBRYO; EYE INJURY; FIBROSIS; LENS EPITHELIUM; MESENCHYMAL STEM CELL; MYOFIBROBLAST; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; WOUND HEALING; ANIMAL; CELL DIFFERENTIATION; CHICK EMBRYO; CYTOLOGY; GENE EXPRESSION REGULATION; GENETICS; METABOLISM;

ANIMALS; ANTIGENS, SURFACE; CELL DIFFERENTIATION; CHICK EMBRYO; FIBROSIS; GENE EXPRESSION REGULATION; MESENCHYMAL STEM CELLS; MYOD PROTEIN; WOUND HEALING;

EID: 77956381241     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0910382107     Document Type: Article

References (29)

1. Radisky DC, Kenny PA, Bissell MJ (2007) Fibrosis and cancer: Do myofibroblasts come also from epithelial cells via EMT? J Cell Biochem 101:830-839.
2. Eyden B (2008) The myofibroblast: Phenotypic characterization as a prerequisite to understanding its functions in translational medicine. J Cell Mol Med 12:22-37.
3. Polyak K, Weinberg RA (2009) Transitions between epithelial and mesenchymal states: Acquisition of malignant and stem cell traits. Nat Rev Cancer 9:265-273.
4. Baum B, Settleman J, Quinlan MP (2008) Transitions between epithelial and mesenchymal states in development and disease. Semin Cell Dev Biol 19:294-308.
5. Lee JM, Dedhar S, Kalluri R, Thompson EW (2006) The epithelial- mesenchymal transition: New insights in signaling, development, and disease. J Cell Biol 172: 973-981.
6. Rønnov-Jessen L, Villadsen R, Edwards JC, Petersen OW (2002) Differential expression of a chloride intracellular channel gene, CLIC4, in transforming growth factor-β1- mediated conversion of fibroblasts to myofibroblasts. Am J Pathol 161:471-480.
7. Tomasek JJ, Gabbiani G, Hinz B, Chaponnier C, Brown RA (2002) Myofibroblasts and mechano-regulation of connective tissue remodelling. Nat Rev Mol Cell Biol 3: 349-363.
8. Humphreys BD, et al. (2010) Fate tracing reveals the pericyte and not epithelial origin of myofibroblasts in kidney fibrosis. Am J Pathol 176:85-97.
9. Brittan M, et al. (2002) Bone marrow derivation of pericryptal myofibroblasts in the mouse and human small intestine and colon. Gut 50:752-757.
10. Hashimoto N, Jin H, Liu T, Chensue SW, Phan SH (2004) Bone marrow-derived progenitor cells in pulmonary fibrosis. J Clin Invest 113:243-252.
11. Walker JL, Wolff IM, Zhang L, Menko AS (2007) Activation of SRC kinases signals induction of posterior capsule opacification. Invest Ophthalmol Vis Sci 48:2214-2223.
12. Gerhart J, et al. (2001) MyoD-positive myoblasts are present in mature fetal organs lacking skeletal muscle. J Cell Biol 155:381-392.
13. Strony R, et al. (2005) NeuroM and MyoD are expressed in separate subpopulations of cells in the pregastrulating epiblast. Gene Expr Patterns 5:387-395.
14. Gerhart J, et al. (2004) Epiblast cells that express MyoD recruit pluripotent cells to the skeletal muscle lineage. J Cell Biol 164:739-746.
15. Bellairs R (1986) The primitive streak. Anat Embryol (Berl) 174:1-14.
16. Gerhart J, et al. (2006) MyoD-positive epiblast cells regulate skeletal muscle differentiation in the embryo. J Cell Biol 175:283-292.
17. Asakura A, Lyons GE, Tapscott SJ (1995) The regulation of MyoD gene expression: Conserved elements mediate expression in embryonic axial muscle. Dev Biol 171: 386-398.
18. Chen JC, Mortimer J, Marley J, Goldhamer DJ (2005) MyoD-cre transgenic mice: A model for conditional mutagenesis and lineage tracing of skeletal muscle. Genesis 41: 116-121.
19. Grounds MD, Garrett KL, Beilharz MW (1992) The transcription of MyoD1 and myogenin genes in thymic cells in vivo. Exp Cell Res 198:357-361.
20. Gerhart J, et al. (2009) Noggin producing, MyoD-positive cells are crucial for eye development. Dev Biol 336:30-41.
21. Davis RL, Weintraub H, Lassar AB (1987) Expression of a single transfected cDNA converts fibroblasts to myoblasts. Cell 51:987-1000.
22. Choi J, et al. (1990) MyoD converts primary dermal fibroblasts, chondroblasts, smooth muscle, and retinal pigmented epithelial cells into striated mononucleated myoblasts and multinucleated myotubes. Proc Natl Acad Sci USA 87:7988-7992.
23. Gerhart J, et al. (2000) DNA dendrimers localize MyoD mRNA in presomitic tissues of the chick embryo. J Cell Biol 149:825-834.
24. Gerhart J, et al. (2004) Visualizing the needle in the haystack: In situ hybridization with fluorescent dendrimers. Biol Proced Online 6:149-156.
25. Hinz B, et al. (2007) The myofibroblast: One function, multiple origins. Am J Pathol 170:1807-1816.
26. Cattaneo E, McKay R (1990) Proliferation and differentiation of neuronal stem cells regulated by nerve growth factor. Nature 347:762-765.
27. Bai Y, Du L, Shen L, Zhang Y, Zhang L (2009) GPR56 is highly expressed in neural stem cells but downregulated during differentiation. Neuroreport 20:918-922.
28. Hinz B (2007) Formation and function of the myofibroblast during tissue repair. J Invest Dermatol 127:526-537.
29. Mayer DC, Leinwand LA (1997) Sarcomeric gene expression and contractility in myofibroblasts. J Cell Biol 139:1477-1484.