Rapid profiling of the antigen regions recognized by serum antibodies using massively parallel sequencing of antigen-specific libraries

PLoS ONE

Volumn 9, Issue 12, 2014, Pages

  Domina, Maria ^a   Cariccio, Veronica Lanza ^a   Benfatto, Salvatore ^a   D'Aliberti, Deborah ^a   Venza, Mario ^a   Borgogni, Erica ^b   Castellino, Flora ^b   Biondo, Carmelo ^a   D'Andrea, Daniel ^c   Grassi, Luigi ^c   Tramontano, Anna ^c   Teti, Giuseppe ^a,d   Felici, Franco ^e   Beninati, Concetta ^a,d  

^a UNIVERSITY OF MESSINA   (Italy)

^b NOVARTIS VACCINES AND DIAGNOSTICS   (Italy)

^c SAPIENZA UNIVERSITY OF ROME   (Italy)

^d Charybdis Vaccines Srl   (Italy)

^e UNIVERSITY OF MOLISE   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

EPITOPE; LYMPHOCYTE ANTIBODY; BACTERIAL ANTIGEN; MONOCLONAL ANTIBODY; PEPTIDE LIBRARY;

ANALYTIC METHOD; ARTICLE; BACTERIAL GENE; BACTERIAL VIRULENCE; EPITOPE MAPPING; HUMAN; IMMUNOREACTIVITY; INTERMETHOD COMPARISON; MOLECULAR BIOLOGY; MOLECULAR LIBRARY; NADA GENE; NEISSERIA MENINGITIDIS; NORMAL HUMAN; PHAGE BASED REPRESENTATION OF IMMUNO LIGAND EPITOPE REPERTOIRE; PHAGE DISPLAY; QUALITY CONTROL; SEQUENCE ANALYSIS; VACCINATION; AMINO ACID SEQUENCE; BLOOD; EPIDEMIC MENINGITIS; GENETICS; HIGH THROUGHPUT SEQUENCING; IMMUNOLOGY; ISOLATION AND PURIFICATION; MICROBIOLOGY; PATHOGENICITY; PEPTIDE LIBRARY;

AMINO ACID SEQUENCE; ANTIBODIES, MONOCLONAL; ANTIGENS, BACTERIAL; EPITOPES; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; MENINGITIS, MENINGOCOCCAL; NEISSERIA MENINGITIDIS; PEPTIDE LIBRARY;

EID: 84956628408     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0114159     Document Type: Article

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