Peptides Targeting EGF Block the EGF-EGFR Interaction

ChemBioChem

Volumn 17, Issue 8, 2016, Pages 702-711

  Guardiola, Salvador ^a   Díaz Lobo, Mireia ^a   Seco, Jesús ^a   García, Jesús ^a   Nevola, Laura ^a   Giralt, Ernest ^a,b  

^a INSTITUTE FOR RESEARCH IN BIOMEDICINE   (Spain)

^b UNIVERSITY OF BARCELONA   (Spain)

Author keywords

cancer therapy; membrane receptors; peptides; protein protein interaction; SAW

Indexed keywords

ARGININE; DISULFIDE; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; GLUTAMIC ACID; IMMOBILIZED PROTEIN; LEUCINE; POLYPEPTIDE; MOLECULAR LIBRARY; PEPTIDE; PEPTIDE LIBRARY; PROTEIN BINDING;

ALPHA HELIX; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ARTICLE; BETA SHEET; BINDING AFFINITY; BINDING SITE; CANCER THERAPY; CARBOXY TERMINAL SEQUENCE; CELL PROLIFERATION; CELL VIABILITY ASSAY; CIRCULAR DICHROISM; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYSTAL STRUCTURE; DISULFIDE BOND; DRUG DESIGN; HETERONUCLEAR SINGLE QUANTUM COHERENCE; HUMAN; HUMAN CELL; ISOTHERMAL TITRATION CALORIMETRY; MOLECULAR DOCKING; MOLECULAR DYNAMICS; NITROGEN NUCLEAR MAGNETIC RESONANCE; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; PROTEIN SECONDARY STRUCTURE; PROTON NUCLEAR MAGNETIC RESONANCE; STATIC ELECTRICITY; STOICHIOMETRY; XTT ASSAY; ANTAGONISTS AND INHIBITORS; CELL SURVIVAL; CHEMISTRY; CONFORMATION; DOSE RESPONSE; DRUG EFFECTS; MOLECULAR LIBRARY; MOLECULAR MODEL; PEPTIDE LIBRARY; PHARMACOLOGY; STRUCTURE ACTIVITY RELATION; SYNTHESIS; TUMOR CELL LINE;

AMINO ACID SEQUENCE; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; EPIDERMAL GROWTH FACTOR; HUMANS; MODELS, MOLECULAR; MOLECULAR CONFORMATION; PEPTIDE LIBRARY; PEPTIDES; PROTEIN BINDING; RECEPTOR, EPIDERMAL GROWTH FACTOR; SMALL MOLECULE LIBRARIES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84956598652     PISSN: 14394227     EISSN: 14397633     Source Type: Journal    
DOI: 10.1002/cbic.201500525     Document Type: Article

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