-
1
-
-
44249125258
-
Challenges of detecting EGFR T790M in gefitinib/erlotinib-resistant tumours
-
Jänne PA. Challenges of detecting EGFR T790M in gefitinib/erlotinib-resistant tumours. Lung Cancer 2008;60:s3-9.
-
(2008)
Lung Cancer
, vol.60
-
-
Jänne, P.A.1
-
2
-
-
18244371651
-
Acquired resistance of lung adenocarcinomas to gefitinib or erlotinib is associated with a second mutation in the EGFR kinase domain
-
Pao W, Miller VA, Politi KA, Riely GJ, Somwar R, Zakowski MF, et al. Acquired resistance of lung adenocarcinomas to gefitinib or erlotinib is associated with a second mutation in the EGFR kinase domain. PLoS Med 2005;2:e73.
-
(2005)
PLoS Med
, vol.2
-
-
Pao, W.1
Miller, V.A.2
Politi, K.A.3
Riely, G.J.4
Somwar, R.5
Zakowski, M.F.6
-
3
-
-
20844450219
-
EGFR mutation and response of lung cancer to gefitinib
-
Toyooka S, Kiura K, Mitsudomi T. EGFR mutation and response of lung cancer to gefitinib. N Engl J Med 2005;352:2136.
-
(2005)
N Engl J Med
, vol.352
, pp. 2136
-
-
Toyooka, S.1
Kiura, K.2
Mitsudomi, T.3
-
4
-
-
13844317894
-
EGFR mutation and resistance of non-small-cell lung cancer to gefitinib
-
Kobayashi S, Boggon TJ, Dayaram T, Jänne PA, Kocher O, Meyerson M, et al. EGFR mutation and resistance of non-small-cell lung cancer to gefitinib. N Engl J Med 2005;352:786-92.
-
(2005)
N Engl J Med
, vol.352
, pp. 786-792
-
-
Kobayashi, S.1
Boggon, T.J.2
Dayaram, T.3
Jänne, P.A.4
Kocher, O.5
Meyerson, M.6
-
5
-
-
61549108338
-
EGFR T790M mutation: a double role in lung cancer cell survival?
-
Suda K, Onozato R, Yatabe Y, Mitsudomi T. EGFR T790M mutation: a double role in lung cancer cell survival? J Thorac Oncol 2009;4:1-4.
-
(2009)
J Thorac Oncol
, vol.4
, pp. 1-4
-
-
Suda, K.1
Onozato, R.2
Yatabe, Y.3
Mitsudomi, T.4
-
6
-
-
77950460014
-
Acquired resistance to gefitinib: The contribution of mechanisms other than the T790M, MET, and HGF status
-
Onitsuka T, Uramoto H, Nose N, Takenoyama M, Hanagiri T, Sugio K, et al. Acquired resistance to gefitinib: The contribution of mechanisms other than the T790M, MET, and HGF status. Lung Cancer 2010;68:198-203.
-
(2010)
Lung Cancer
, vol.68
, pp. 198-203
-
-
Onitsuka, T.1
Uramoto, H.2
Nose, N.3
Takenoyama, M.4
Hanagiri, T.5
Sugio, K.6
-
7
-
-
34247559012
-
EGFR mutation status in pleural fluid predicts tumor responsiveness and resistance to gefitinib
-
Soh J, Toyooka S, Ichihara S, Suehisa H, Kobayashi N, Ito S, et al. EGFR mutation status in pleural fluid predicts tumor responsiveness and resistance to gefitinib. Lung Cancer 2007;56:445-8.
-
(2007)
Lung Cancer
, vol.56
, pp. 445-448
-
-
Soh, J.1
Toyooka, S.2
Ichihara, S.3
Suehisa, H.4
Kobayashi, N.5
Ito, S.6
-
8
-
-
28444455958
-
Inherited susceptibility to lung cancer may be associated with the T790M drug resistance mutation in EGFR
-
Bell DW, Gore I, Okimoto RA, Godin-Heymann N, Sordella R, Mulloy R, et al. Inherited susceptibility to lung cancer may be associated with the T790M drug resistance mutation in EGFR. Nat Genet 2005;37:1315-6.
-
(2005)
Nat Genet
, vol.37
, pp. 1315-1316
-
-
Bell, D.W.1
Gore, I.2
Okimoto, R.A.3
Godin-Heymann, N.4
Sordella, R.5
Mulloy, R.6
-
9
-
-
21144439000
-
Irreversible inhibitors of the EGF receptor may circumvent acquired resistance to gefitinib
-
Kwak EL, Sordella R, Bell DW, Godin-Heymann N, Okimoto RA, Brannigan BW, et al. Irreversible inhibitors of the EGF receptor may circumvent acquired resistance to gefitinib. Proc Natl Acad Sci U S A 2005;102:7665-70.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 7665-7670
-
-
Kwak, E.L.1
Sordella, R.2
Bell, D.W.3
Godin-Heymann, N.4
Okimoto, R.A.5
Brannigan, B.W.6
-
10
-
-
54849404327
-
Accuracy of epidermal growth factor receptor gene mutation analysis by direct sequencing method based on small biopsy specimens from patients with non-small cell lung cancer: analysis of results in 19 patients
-
Masago K, Fujita S, Mio T, Ichikawa M, Sakuma K, Kim YH, et al. Accuracy of epidermal growth factor receptor gene mutation analysis by direct sequencing method based on small biopsy specimens from patients with non-small cell lung cancer: analysis of results in 19 patients. Int J Clin Oncol 2008;13:442-6.
-
(2008)
Int J Clin Oncol
, vol.13
, pp. 442-446
-
-
Masago, K.1
Fujita, S.2
Mio, T.3
Ichikawa, M.4
Sakuma, K.5
Kim, Y.H.6
-
11
-
-
38949177364
-
Peptide nucleic acid-locked nucleic acid polymerase chain reaction clamp-based detection test for gefitinib-refractory T790M epidermal growth factor receptor mutation
-
Miyazawa H, Tanaka T, Nagai Y, Matsuoka M, Huqun, Sutani A, et al. Peptide nucleic acid-locked nucleic acid polymerase chain reaction clamp-based detection test for gefitinib-refractory T790M epidermal growth factor receptor mutation. Cancer Sci 2008;99:595-600.
-
(2008)
Cancer Sci
, vol.99
, pp. 595-600
-
-
Miyazawa, H.1
Tanaka, T.2
Nagai, Y.3
Matsuoka, M.4
Huqun5
Sutani, A.6
-
12
-
-
75049083402
-
Clinicopathologic and molecular features of epidermal growth factor receptor T790M mutation and c-MET amplification in tyrosine kinase inhibitor-resistant chinese non-small cell lung cancer
-
Chen HJ, Mok TS, Chen ZH, Guo AL, Zhang XC, Su J, et al. Clinicopathologic and molecular features of epidermal growth factor receptor T790M mutation and c-MET amplification in tyrosine kinase inhibitor-resistant chinese non-small cell lung cancer. Pathol Oncol Res 2009;15:651-8.
-
(2009)
Pathol Oncol Res
, vol.15
, pp. 651-658
-
-
Chen, H.J.1
Mok, T.S.2
Chen, Z.H.3
Guo, A.L.4
Zhang, X.C.5
Su, J.6
-
13
-
-
73649102105
-
Preexistence and clonal selection of MET amplification in EGFR mutant NSCLC
-
Turke AB, Zejnullahu K, Wu YL, Song Y, Dias-Santagata D, Lifshits E, et al. Preexistence and clonal selection of MET amplification in EGFR mutant NSCLC. Cancer Cell 2010;17:77-88.
-
(2010)
Cancer Cell
, vol.17
, pp. 77-88
-
-
Turke, A.B.1
Zejnullahu, K.2
Wu, Y.L.3
Song, Y.4
Dias-Santagata, D.5
Lifshits, E.6
-
14
-
-
45149084723
-
First-line gefitinib in patients with advanced non-small-cell lung cancer harboring somatic EGFR mutations
-
Sequist LV, Martins RG, Spigel D, Grunberg SM, Spira A, Jänne PA, et al. First-line gefitinib in patients with advanced non-small-cell lung cancer harboring somatic EGFR mutations. J Clin Oncol 2008;26:2442-9.
-
(2008)
J Clin Oncol
, vol.26
, pp. 2442-2449
-
-
Sequist, L.V.1
Martins, R.G.2
Spigel, D.3
Grunberg, S.M.4
Spira, A.5
Jänne, P.A.6
-
15
-
-
62449250134
-
MET gene amplification or EGFR mutation activate MET in lung cancers untreated with EGFR tyrosine kinase inhibitors
-
Kubo T, Yamamoto H, Lockwood WW, Valencia I, Soh J, Peyton M, et al. MET gene amplification or EGFR mutation activate MET in lung cancers untreated with EGFR tyrosine kinase inhibitors. Int J Cancer 2009;124:1778-84.
-
(2009)
Int J Cancer
, vol.124
, pp. 1778-1784
-
-
Kubo, T.1
Yamamoto, H.2
Lockwood, W.W.3
Valencia, I.4
Soh, J.5
Peyton, M.6
-
16
-
-
58149234399
-
Effects of erlotinib in EGFR mutated non-small cell lung cancers with resistance to gefitinib
-
Costa DB, Nguyen KS, Cho BC, Sequist LV, Jackman DM, Riely GJ, et al. Effects of erlotinib in EGFR mutated non-small cell lung cancers with resistance to gefitinib. Clin Cancer Res 2008;14:7060-7.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 7060-7067
-
-
Costa, D.B.1
Nguyen, K.S.2
Cho, B.C.3
Sequist, L.V.4
Jackman, D.M.5
Riely, G.J.6
-
17
-
-
33750302365
-
Analysis of epidermal growth factor receptor gene mutation in patients with non-small cell lung cancer and acquired resistance to gefitinib
-
Kosaka T, Yatabe Y, Endoh H, Yoshida K, Hida T, Tsuboi M, et al. Analysis of epidermal growth factor receptor gene mutation in patients with non-small cell lung cancer and acquired resistance to gefitinib. Clin Cancer Res 2006;12:5764-9.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 5764-5769
-
-
Kosaka, T.1
Yatabe, Y.2
Endoh, H.3
Yoshida, K.4
Hida, T.5
Tsuboi, M.6
-
18
-
-
33751292685
-
Novel D761Y and common secondary T790M mutations in epidermal growth factor receptor-mutant lung adenocarcinomas with acquired resistance to kinase inhibitors
-
Balak MN, Gong Y, Riely GJ, Somwar R, Li AR, Zakowski MF, et al. Novel D761Y and common secondary T790M mutations in epidermal growth factor receptor-mutant lung adenocarcinomas with acquired resistance to kinase inhibitors. Clin Cancer Res 2006;12:6494-501.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 6494-6501
-
-
Balak, M.N.1
Gong, Y.2
Riely, G.J.3
Somwar, R.4
Li, A.R.5
Zakowski, M.F.6
-
19
-
-
38049150665
-
MET amplification occurs with or without T790M mutations in EGFR mutant lung tumors with acquired resistance to gefitinib or erlotinib
-
Bean J, Brennan C, Shih JY, Riely G, Viale A, Wang L, et al. MET amplification occurs with or without T790M mutations in EGFR mutant lung tumors with acquired resistance to gefitinib or erlotinib. Proc Natl Acad Sci U S A 2007;104:20932-7.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 20932-20937
-
-
Bean, J.1
Brennan, C.2
Shih, J.Y.3
Riely, G.4
Viale, A.5
Wang, L.6
-
20
-
-
57349141411
-
EGFR genetic heterogeneity of nonsmall cell lung cancers contributing to acquired gefitinib resistance
-
Jiang SX, Yamashita K, Yamamoto M, Piao CJ, Umezawa A, Saegusa M, et al. EGFR genetic heterogeneity of nonsmall cell lung cancers contributing to acquired gefitinib resistance. Int J Cancer 2008;123:2480-6.
-
(2008)
Int J Cancer
, vol.123
, pp. 2480-2486
-
-
Jiang, S.X.1
Yamashita, K.2
Yamamoto, M.3
Piao, C.J.4
Umezawa, A.5
Saegusa, M.6
-
21
-
-
41949119173
-
Differential responses to erlotinib in epidermal growth factor receptor (EGFR)-mutated lung cancers with acquired resistance to gefitinib carrying the L747S or T790M secondary mutations
-
Costa DB, Schumer ST, Tenen DG, Kobayashi S. Differential responses to erlotinib in epidermal growth factor receptor (EGFR)-mutated lung cancers with acquired resistance to gefitinib carrying the L747S or T790M secondary mutations. J Clin Oncol 2008;26:1182-4.
-
(2008)
J Clin Oncol
, vol.26
, pp. 1182-1184
-
-
Costa, D.B.1
Schumer, S.T.2
Tenen, D.G.3
Kobayashi, S.4
-
22
-
-
33644506118
-
Lack of response to erlotinib after progression on gefitinib in patients with advanced non-small cell lung cancer
-
Viswanathan A, Pillot G, Govindan R. Lack of response to erlotinib after progression on gefitinib in patients with advanced non-small cell lung cancer. Lung Cancer 2005;50:417-8.
-
(2005)
Lung Cancer
, vol.50
, pp. 417-418
-
-
Viswanathan, A.1
Pillot, G.2
Govindan, R.3
-
23
-
-
41749085999
-
Lung adenocarcinoma with good response to erlotinib after gefitinib treatment failure and acquired T790M mutation
-
Wu SG, Shih JY, Yu CJ, Yang PC. Lung adenocarcinoma with good response to erlotinib after gefitinib treatment failure and acquired T790M mutation. J Thorac Oncol 2008;3:451-2.
-
(2008)
J Thorac Oncol
, vol.3
, pp. 451-452
-
-
Wu, S.G.1
Shih, J.Y.2
Yu, C.J.3
Yang, P.C.4
-
24
-
-
32944470677
-
Modern treatment of lung cancer: case 2 Response to erlotinib after failure of gefitinib in a patient with advanced non-small-cell lung carcinoma
-
Garfield DH. Modern treatment of lung cancer: case 2. Response to erlotinib after failure of gefitinib in a patient with advanced non-small-cell lung carcinoma. J Clin Oncol 2005;23:7738-40.
-
(2005)
J Clin Oncol
, vol.23
, pp. 7738-7740
-
-
Garfield, D.H.1
-
25
-
-
34447262600
-
Phase II study of erlotinib in advanced non-small-cell lung cancer after failure of gefitinib
-
Cho BC, Im CK, Park MS, Kim SK, Chang J, Park JP, et al. Phase II study of erlotinib in advanced non-small-cell lung cancer after failure of gefitinib. J Clin Oncol 2007;25:2528-33.
-
(2007)
J Clin Oncol
, vol.25
, pp. 2528-2533
-
-
Cho, B.C.1
Im, C.K.2
Park, M.S.3
Kim, S.K.4
Chang, J.5
Park, J.P.6
-
26
-
-
67449115698
-
Erlotinib after Gefitinib failure in female never-smoker Asian patients with pulmonary adenocarcinoma
-
Sim SH, Han SW, Oh DY, Lee SH, Kim DW, Im SA, et al. Erlotinib after Gefitinib failure in female never-smoker Asian patients with pulmonary adenocarcinoma. Lung Cancer 2009;65:204-7.
-
(2009)
Lung Cancer
, vol.65
, pp. 204-207
-
-
Sim, S.H.1
Han, S.W.2
Oh, D.Y.3
Lee, S.H.4
Kim, D.W.5
Im, S.A.6
-
27
-
-
77951895524
-
Erlotinib as salvage treatment after failure to first-line gefitinib in non-small cell lung cancer
-
Wong MK, Lo AI, Lam B, Lam WK, Ip MS, Ho JC. Erlotinib as salvage treatment after failure to first-line gefitinib in non-small cell lung cancer. Cancer Chemother Pharmacol 2010;65:1023-8.
-
(2010)
Cancer Chemother Pharmacol
, vol.65
, pp. 1023-1028
-
-
Wong, M.K.1
Lo, A.I.2
Lam, B.3
Lam, W.K.4
Ip, M.S.5
Ho, J.C.6
-
28
-
-
56749178852
-
Phase II study of erlotinib as a salvage treatment for non-small-cell lung cancer patients after failure of gefitinib treatment
-
Lee DH, Kim SW, Suh C, Yoon DH, Yi EJ, Lee JS. Phase II study of erlotinib as a salvage treatment for non-small-cell lung cancer patients after failure of gefitinib treatment. Ann Oncol 2008;19:2039-42.
-
(2008)
Ann Oncol
, vol.19
, pp. 2039-2042
-
-
Lee, D.H.1
Kim, S.W.2
Suh, C.3
Yoon, D.H.4
Yi, E.J.5
Lee, J.S.6
-
29
-
-
58149139728
-
Erlotinib after failure of gefitinib in patients with advanced non-small cell lung cancer previously responding to gefitinib
-
Vasile E, Tibaldi C, Chella A, Falcone A. Erlotinib after failure of gefitinib in patients with advanced non-small cell lung cancer previously responding to gefitinib. J Thorac Oncol 2008;3:912-4.
-
(2008)
J Thorac Oncol
, vol.3
, pp. 912-914
-
-
Vasile, E.1
Tibaldi, C.2
Chella, A.3
Falcone, A.4
-
30
-
-
34249075147
-
MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling
-
Engelman JA, Zejnullahu K, Mitsudomi T, Song Y, Hyland C, Park JO, et al. MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling. Science 2007;316:1039-43.
-
(2007)
Science
, vol.316
, pp. 1039-1043
-
-
Engelman, J.A.1
Zejnullahu, K.2
Mitsudomi, T.3
Song, Y.4
Hyland, C.5
Park, J.O.6
-
31
-
-
33748074447
-
Presence of epidermal growth factor receptor gene T790M mutation as a minor clone in non-small cell lung cancer
-
Inukai M, Toyooka S, Ito S, Asano H, Ichihara S, Soh J, et al. Presence of epidermal growth factor receptor gene T790M mutation as a minor clone in non-small cell lung cancer. Cancer Res 2006;66:7854-8.
-
(2006)
Cancer Res
, vol.66
, pp. 7854-7858
-
-
Inukai, M.1
Toyooka, S.2
Ito, S.3
Asano, H.4
Ichihara, S.5
Soh, J.6
-
32
-
-
65249127504
-
Noninvasive detection of EGFR T790M in gefitinib or erlotinib resistant non-small cell lung cancer
-
Kuang Y, Rogers A, Yeap BY, Wang L, Makrigiorgos M, Vetrand K, et al. Noninvasive detection of EGFR T790M in gefitinib or erlotinib resistant non-small cell lung cancer. Clin Cancer Res 2009;15:2630-6.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 2630-2636
-
-
Kuang, Y.1
Rogers, A.2
Yeap, B.Y.3
Wang, L.4
Makrigiorgos, M.5
Vetrand, K.6
-
33
-
-
77953362931
-
New strategies to overcome limitations of reversible EGFR tyrosine kinase inhibitor therapy in non-small cell lung cancer
-
Doebele RC, Oton AB, Peled N, Camidge DR, Bunn PA Jr. New strategies to overcome limitations of reversible EGFR tyrosine kinase inhibitor therapy in non-small cell lung cancer. Lung Cancer 2010;69:1-12.
-
(2010)
Lung Cancer
, vol.69
, pp. 1-12
-
-
Doebele, R.C.1
Oton, A.B.2
Peled, N.3
Camidge, D.R.4
Bunn Jr, P.A.5
-
34
-
-
33749435816
-
Allelic dilution obscures detection of a biologically significant resistance mutation in EGFR-amplified lung cancer
-
Engelman JA, Mukohara T, Zejnullahu K, Lifshits E, Borrás AM, Gale CM, et al. Allelic dilution obscures detection of a biologically significant resistance mutation in EGFR-amplified lung cancer. J Clin Invest 2006;116:2695-706.
-
(2006)
J Clin Invest
, vol.116
, pp. 2695-2706
-
-
Engelman, J.A.1
Mukohara, T.2
Zejnullahu, K.3
Lifshits, E.4
Borrás, A.M.5
Gale, C.M.6
|