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Volumn 117, Issue 3, 2016, Pages 760-768

Overexpression of Hif-1α in Mesenchymal Stem Cells Affects Cell-Autonomous Angiogenic and Osteogenic Parameters

Author keywords

ADENOVIRUS; ANGIOGENESIS; Hif 1 ; MIGRATION; OSTEOGENESIS

Indexed keywords

ADENOVIRUS VECTOR; BONE MORPHOGENETIC PROTEIN 2; HYPOXIA INDUCIBLE FACTOR 1ALPHA; TRANSCRIPTION FACTOR RUNX2; HIF1A PROTEIN, HUMAN;

EID: 84955720630     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.25361     Document Type: Article
Times cited : (34)

References (41)
  • 1
    • 0032029899 scopus 로고    scopus 로고
    • Bone regeneration by implantation of purified, culture-expanded human mesenchymal stem cells
    • Bruder SP, Kurth AA, Shea M, Hayes WC, Jaiswal N, Kadiyala S,. 1998. Bone regeneration by implantation of purified, culture-expanded human mesenchymal stem cells. J Orthop Res 16: 155-162.
    • (1998) J Orthop Res , vol.16 , pp. 155-162
    • Bruder, S.P.1    Kurth, A.A.2    Shea, M.3    Hayes, W.C.4    Jaiswal, N.5    Kadiyala, S.6
  • 2
    • 84936995144 scopus 로고    scopus 로고
    • Body management: Mesenchymal stem cells control the internal regenerator
    • Epub ahead of print
    • Caplan AI, Hariri R,. 2015. Body management: Mesenchymal stem cells control the internal regenerator. Stem Cells Transl Med. [Epub ahead of print].
    • (2015) Stem Cells Transl Med
    • Caplan, A.I.1    Hariri, R.2
  • 5
    • 0033084785 scopus 로고    scopus 로고
    • Engineered pluripotent mesenchymal cells integrate and differentiate in regenerating bone: A novel cell-mediated gene therapy
    • Gazit D, Turgeman G, Kelley P, Wang E, Jalenak M, Zilberman Y, Moutsatsos I,. 1999. Engineered pluripotent mesenchymal cells integrate and differentiate in regenerating bone: A novel cell-mediated gene therapy. J Gene Med 1: 121-133.
    • (1999) J Gene Med , vol.1 , pp. 121-133
    • Gazit, D.1    Turgeman, G.2    Kelley, P.3    Wang, E.4    Jalenak, M.5    Zilberman, Y.6    Moutsatsos, I.7
  • 6
    • 34249113091 scopus 로고    scopus 로고
    • Hypoxia enhances proliferation and tissue formation of human mesenchymal stem cells
    • Grayson WL, Zhao F, Bunnell B, Ma T,. 2007. Hypoxia enhances proliferation and tissue formation of human mesenchymal stem cells. Biochem Biophys Res Commun 358: 948-953.
    • (2007) Biochem Biophys Res Commun , vol.358 , pp. 948-953
    • Grayson, W.L.1    Zhao, F.2    Bunnell, B.3    Ma, T.4
  • 7
    • 80051491350 scopus 로고    scopus 로고
    • Baicalin, a flavone, induces the differentiation of cultured osteoblasts: An action via the Wnt/beta-catenin signaling pathway
    • Guo AJ, Choi RC, Cheung AW, Chen VP, Xu SL, Dong TT, Chen JJ, Tsim KW,. 2011. Baicalin, a flavone, induces the differentiation of cultured osteoblasts: An action via the Wnt/beta-catenin signaling pathway. J Biol Chem 286: 27882-27893.
    • (2011) J Biol Chem , vol.286 , pp. 27882-27893
    • Guo, A.J.1    Choi, R.C.2    Cheung, A.W.3    Chen, V.P.4    Xu, S.L.5    Dong, T.T.6    Chen, J.J.7    Tsim, K.W.8
  • 8
    • 73449086300 scopus 로고    scopus 로고
    • Culture effects of epidermal growth factor (EGF) and basic fibroblast growth factor (bFGF) on cryopreserved human adipose-derived stromal/stem cell proliferation and adipogenesis
    • Hebert TL, Wu X, Yu G, Goh BC, Halvorsen YD, Wang Z, Moro C, Gimble JM,. 2009. Culture effects of epidermal growth factor (EGF) and basic fibroblast growth factor (bFGF) on cryopreserved human adipose-derived stromal/stem cell proliferation and adipogenesis. J Tissue Eng Regen Med 3: 553-561.
    • (2009) J Tissue Eng Regen Med , vol.3 , pp. 553-561
    • Hebert, T.L.1    Wu, X.2    Yu, G.3    Goh, B.C.4    Halvorsen, Y.D.5    Wang, Z.6    Moro, C.7    Gimble, J.M.8
  • 9
    • 77349087595 scopus 로고    scopus 로고
    • Low physiologic oxygen tensions reduce proliferation and differentiation of human multipotent mesenchymal stromal cells
    • Holzwarth C, Vaegler M, Gieseke F, Pfister SM, Handgretinger R, Kerst G, Muller I,. 2010. Low physiologic oxygen tensions reduce proliferation and differentiation of human multipotent mesenchymal stromal cells. BMC Cell Biol 11: 11.
    • (2010) BMC Cell Biol , vol.11 , pp. 11
    • Holzwarth, C.1    Vaegler, M.2    Gieseke, F.3    Pfister, S.M.4    Handgretinger, R.5    Kerst, G.6    Muller, I.7
  • 10
    • 77952111459 scopus 로고    scopus 로고
    • MiR-210?micromanager of the hypoxia pathway
    • Huang X, Le QT, Giaccia AJ,. 2010. MiR-210?micromanager of the hypoxia pathway. Trends Mol Med 16: 230-237.
    • (2010) Trends Mol Med , vol.16 , pp. 230-237
    • Huang, X.1    Le, Q.T.2    Giaccia, A.J.3
  • 12
    • 0029944965 scopus 로고    scopus 로고
    • Dimerization, DNA binding, and transactivation properties of hypoxia-inducible factor 1
    • Jiang BH, Rue E, Wang GL, Roe R, Semenza GL,. 1996. Dimerization, DNA binding, and transactivation properties of hypoxia-inducible factor 1. J Biol Chem 271: 17771-17778.
    • (1996) J Biol Chem , vol.271 , pp. 17771-17778
    • Jiang, B.H.1    Rue, E.2    Wang, G.L.3    Roe, R.4    Semenza, G.L.5
  • 13
    • 0032538797 scopus 로고    scopus 로고
    • Signal transduction in hypoxic cells: Inducible nuclear translocation and recruitment of the CBP/p300 coactivator by the hypoxia-inducible factor-1alpha
    • Kallio PJ, Okamoto K, O'Brien S, Carrero P, Makino Y, Tanaka H, Poellinger L,. 1998. Signal transduction in hypoxic cells: Inducible nuclear translocation and recruitment of the CBP/p300 coactivator by the hypoxia-inducible factor-1alpha. EMBO J 17: 6573-6586.
    • (1998) EMBO J , vol.17 , pp. 6573-6586
    • Kallio, P.J.1    Okamoto, K.2    O'Brien, S.3    Carrero, P.4    Makino, Y.5    Tanaka, H.6    Poellinger, L.7
  • 14
    • 0033525830 scopus 로고    scopus 로고
    • Regulation of the hypoxia-inducible transcription factor 1alpha by the ubiquitin-proteasome pathway
    • Kallio PJ, Wilson WJ, O'Brien S, Makino Y, Poellinger L,. 1999. Regulation of the hypoxia-inducible transcription factor 1alpha by the ubiquitin-proteasome pathway. J Biol Chem 274: 6519-6525.
    • (1999) J Biol Chem , vol.274 , pp. 6519-6525
    • Kallio, P.J.1    Wilson, W.J.2    O'Brien, S.3    Makino, Y.4    Poellinger, L.5
  • 16
    • 17144469316 scopus 로고    scopus 로고
    • Autologous bone marrow stromal cells loaded onto porous hydroxyapatite ceramic accelerate bone repair in critical-size defects of sheep long bones
    • Kon E, Muraglia A, Corsi A, Bianco P, Marcacci M, Martin I, Boyde A, Ruspantini I, Chistolini P, Rocca M, et al., 2000. Autologous bone marrow stromal cells loaded onto porous hydroxyapatite ceramic accelerate bone repair in critical-size defects of sheep long bones. J Biomed Mater Res 49: 328-337.
    • (2000) J Biomed Mater Res , vol.49 , pp. 328-337
    • Kon, E.1    Muraglia, A.2    Corsi, A.3    Bianco, P.4    Marcacci, M.5    Martin, I.6    Boyde, A.7    Ruspantini, I.8    Chistolini, P.9    Rocca, M.10
  • 17
    • 1642387020 scopus 로고    scopus 로고
    • Hypoxia-inducible factor (HIF-1) alpha: Its protein stability and biological functions
    • Lee JW, Bae SH, Jeong JW, Kim SH, Kim KW,. 2004. Hypoxia-inducible factor (HIF-1) alpha: Its protein stability and biological functions. Exp Mol Med 36: 1-12.
    • (2004) Exp Mol Med , vol.36 , pp. 1-12
    • Lee, J.W.1    Bae, S.H.2    Jeong, J.W.3    Kim, S.H.4    Kim, K.W.5
  • 18
    • 34547124062 scopus 로고    scopus 로고
    • Hypoxia: A key regulator of angiogenesis in cancer
    • Liao D, Johnson RS,. 2007. Hypoxia: A key regulator of angiogenesis in cancer. Cancer Metastasis Rev 26: 281-290.
    • (2007) Cancer Metastasis Rev , vol.26 , pp. 281-290
    • Liao, D.1    Johnson, R.S.2
  • 22
    • 0028147863 scopus 로고
    • Hypoxic stimulation of vascular endothelial growth factor expression in vitro and in vivo
    • Minchenko A, Bauer T, Salceda S, Caro J,. 1994. Hypoxic stimulation of vascular endothelial growth factor expression in vitro and in vivo. Lab Invest 71: 374-379.
    • (1994) Lab Invest , vol.71 , pp. 374-379
    • Minchenko, A.1    Bauer, T.2    Salceda, S.3    Caro, J.4
  • 23
    • 33744959141 scopus 로고    scopus 로고
    • Expression of vascular endothelial growth factor receptor 1 in bone marrow-derived mesenchymal cells is dependent on hypoxia-inducible factor 1
    • Okuyama H, Krishnamachary B, Zhou YF, Nagasawa H, Bosch-Marce M, Semenza GL,. 2006. Expression of vascular endothelial growth factor receptor 1 in bone marrow-derived mesenchymal cells is dependent on hypoxia-inducible factor 1. J Biol Chem 281: 15554-15563.
    • (2006) J Biol Chem , vol.281 , pp. 15554-15563
    • Okuyama, H.1    Krishnamachary, B.2    Zhou, Y.F.3    Nagasawa, H.4    Bosch-Marce, M.5    Semenza, G.L.6
  • 24
    • 84979634497 scopus 로고    scopus 로고
    • Effects of hypoxia on proliferation of human cord blood-derived mesenchymal stem cells
    • Epub ahead of print
    • Peng L, Shu X, Lang C, Yu X,. 2015. Effects of hypoxia on proliferation of human cord blood-derived mesenchymal stem cells. Cytotechnology. [Epub ahead of print].
    • (2015) Cytotechnology
    • Peng, L.1    Shu, X.2    Lang, C.3    Yu, X.4
  • 26
    • 80053577540 scopus 로고    scopus 로고
    • Hypoxic regulation of mesenchymal stem cell migration: the role of RhoA and HIF-1alpha
    • Raheja LF, Genetos DC, Wong A, Yellowley CE,. 2011. Hypoxic regulation of mesenchymal stem cell migration: The role of RhoA and HIF-1alpha. Cell Biol Int 35: 981-989.
    • (2011) Cell Biol Int , vol.35 , pp. 981-989
    • Raheja, L.F.1    Genetos, D.C.2    Wong, A.3    Yellowley, C.E.4
  • 28
    • 67349123805 scopus 로고    scopus 로고
    • Role of hypoxia-inducible factor-1alpha in angiogenic-osteogenic coupling
    • Riddle RC, Khatri R, Schipani E, Clemens TL,. 2009. Role of hypoxia-inducible factor-1alpha in angiogenic-osteogenic coupling. J Mol Med (Berl) 87: 583-590.
    • (2009) J Mol Med (Berl) , vol.87 , pp. 583-590
    • Riddle, R.C.1    Khatri, R.2    Schipani, E.3    Clemens, T.L.4
  • 29
    • 11144256208 scopus 로고    scopus 로고
    • State-of-the-art tissue engineering: from tissue engineering to organ building
    • Shieh SJ, Vacanti JP,. 2005. State-of-the-art tissue engineering: From tissue engineering to organ building. Surgery 137: 1-7.
    • (2005) Surgery , vol.137 , pp. 1-7
    • Shieh, S.J.1    Vacanti, J.P.2
  • 30
    • 33745266607 scopus 로고    scopus 로고
    • Characterization of the optimal culture conditions for clinical scale production of human mesenchymal stem cells
    • Sotiropoulou PA, Perez SA, Salagianni M, Baxevanis CN, Papamichail M,. 2006. Characterization of the optimal culture conditions for clinical scale production of human mesenchymal stem cells. Stem Cells 24: 462-471.
    • (2006) Stem Cells , vol.24 , pp. 462-471
    • Sotiropoulou, P.A.1    Perez, S.A.2    Salagianni, M.3    Baxevanis, C.N.4    Papamichail, M.5
  • 31
    • 68049138991 scopus 로고    scopus 로고
    • The role of hypoxia-inducible factor in osteogenesis and chondrogenesis
    • Sun X, Wei Y,. 2009. The role of hypoxia-inducible factor in osteogenesis and chondrogenesis. Cytotherapy 11: 261-267.
    • (2009) Cytotherapy , vol.11 , pp. 261-267
    • Sun, X.1    Wei, Y.2
  • 32
    • 34249877724 scopus 로고    scopus 로고
    • Vascular biology and bone formation: Hints from HIF
    • Towler DA,. 2007. Vascular biology and bone formation: Hints from HIF. J Clin Invest 117: 1477-1480.
    • (2007) J Clin Invest , vol.117 , pp. 1477-1480
    • Towler, D.A.1
  • 33
    • 78751535908 scopus 로고    scopus 로고
    • Hypoxia inhibits senescence and maintains mesenchymal stem cell properties through down-regulation of E2A-p21 by HIF-TWIST
    • Tsai CC, Chen YJ, Yew TL, Chen LL, Wang JY, Chiu CH, Hung SC,. 2011. Hypoxia inhibits senescence and maintains mesenchymal stem cell properties through down-regulation of E2A-p21 by HIF-TWIST. Blood 117: 459-469.
    • (2011) Blood , vol.117 , pp. 459-469
    • Tsai, C.C.1    Chen, Y.J.2    Yew, T.L.3    Chen, L.L.4    Wang, J.Y.5    Chiu, C.H.6    Hung, S.C.7
  • 34
    • 84866931844 scopus 로고    scopus 로고
    • Hypoxia promotes osteogenesis but suppresses adipogenesis of human mesenchymal stromal cells in a hypoxia-inducible factor-1 dependent manner
    • Wagegg M, Gaber T, Lohanatha FL, Hahne M, Strehl C, Fangradt M, Tran CL, Schonbeck K, Hoff P, Ode A, et al., 2012. Hypoxia promotes osteogenesis but suppresses adipogenesis of human mesenchymal stromal cells in a hypoxia-inducible factor-1 dependent manner. PLoS ONE 7: e46483.
    • (2012) PLoS ONE , vol.7
    • Wagegg, M.1    Gaber, T.2    Lohanatha, F.L.3    Hahne, M.4    Strehl, C.5    Fangradt, M.6    Tran, C.L.7    Schonbeck, K.8    Hoff, P.9    Ode, A.10
  • 36
    • 0029051439 scopus 로고
    • Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension
    • Wang GL, Jiang BH, Rue EA, Semenza GL,. 1995. Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension. Proc Natl Acad Sci USA 92: 5510-5514.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 5510-5514
    • Wang, G.L.1    Jiang, B.H.2    Rue, E.A.3    Semenza, G.L.4
  • 37
    • 0028816847 scopus 로고
    • Purification and characterization of hypoxia-inducible factor 1
    • Wang GL, Semenza GL,. 1995. Purification and characterization of hypoxia-inducible factor 1. J Biol Chem 270: 1230-1237.
    • (1995) J Biol Chem , vol.270 , pp. 1230-1237
    • Wang, G.L.1    Semenza, G.L.2
  • 39
    • 54549089738 scopus 로고    scopus 로고
    • Hypoxia signalling through mTOR and the unfolded protein response in cancer
    • Wouters BG, Koritzinsky M,. 2008. Hypoxia signalling through mTOR and the unfolded protein response in cancer. Nat Rev Cancer 8: 851-864.
    • (2008) Nat Rev Cancer , vol.8 , pp. 851-864
    • Wouters, B.G.1    Koritzinsky, M.2
  • 40
    • 80052560423 scopus 로고    scopus 로고
    • Hypoxia inhibits osteogenesis in human mesenchymal stem cells through direct regulation of RUNX2 by TWIST
    • Yang DC, Yang MH, Tsai CC, Huang TF, Chen YH, Hung SC,. 2011. Hypoxia inhibits osteogenesis in human mesenchymal stem cells through direct regulation of RUNX2 by TWIST. PLoS ONE 6: e23965.
    • (2011) PLoS ONE , vol.6
    • Yang, D.C.1    Yang, M.H.2    Tsai, C.C.3    Huang, T.F.4    Chen, Y.H.5    Hung, S.C.6
  • 41
    • 80051993827 scopus 로고    scopus 로고
    • Repair of critical-sized rat calvarial defects using genetically engineered bone marrow-derived mesenchymal stem cells overexpressing hypoxia-inducible factor-1alpha
    • Zou D, Zhang Z, Ye D, Tang A, Deng L, Han W, Zhao J, Wang S, Zhang W, Zhu C, et al., 2011. Repair of critical-sized rat calvarial defects using genetically engineered bone marrow-derived mesenchymal stem cells overexpressing hypoxia-inducible factor-1alpha. Stem Cells 29: 1380-1390.
    • (2011) Stem Cells , vol.29 , pp. 1380-1390
    • Zou, D.1    Zhang, Z.2    Ye, D.3    Tang, A.4    Deng, L.5    Han, W.6    Zhao, J.7    Wang, S.8    Zhang, W.9    Zhu, C.10


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