Hypoxia Promotes Osteogenesis but Suppresses Adipogenesis of Human Mesenchymal Stromal Cells in a Hypoxia-Inducible Factor-1 Dependent Manner

PLoS ONE

Volumn 7, Issue 9, 2012, Pages

  Wagegg, Markus ^a,b   Gaber, Timo ^a,b   Lohanatha, Ferenz L ^a,b   Hahne, Martin ^a,b   Strehl, Cindy ^a,b   Fangradt, Monique ^a,b   Tran, Cam Loan ^a,b   Schönbeck, Kerstin ^a,b   Hoff, Paula ^a,b   Ode, Andrea ^a   Perka, Carsten ^a   Duda, Georg N ^a   Buttgereit, Frank ^a,b  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b German Arthritis Research Center   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

HYPOXIA INDUCIBLE FACTOR 1;

ADIPOGENESIS; ARTICLE; BONE DEVELOPMENT; CELL DIFFERENTIATION; CELL LINEAGE; CELL PROLIFERATION; CELL STRUCTURE; CELL SURVIVAL; CONTROLLED STUDY; GENE; GENE EXPRESSION; GENETIC TRANSCRIPTION; GLUT1 GENE; HIF1A GENE; HUMAN; HUMAN CELL; HYPOXIA; LDHA GENE; MESENCHYMAL STROMA CELL; PGK1 GENE; PPARG GENE; PROTEIN ANALYSIS; PROTEIN FUNCTION; RUNX2 GENE; VEGFA GENE;

ADIPOGENESIS; ANTIGENS, CD; CELL HYPOXIA; CELLS, CULTURED; CORE BINDING FACTOR ALPHA 1 SUBUNIT; GENE KNOCKDOWN TECHNIQUES; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MESENCHYMAL STROMAL CELLS; OSTEOGENESIS; PHENOTYPE; PPAR GAMMA; RNA INTERFERENCE; TRANSCRIPTIONAL ACTIVATION; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84866931844     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0046483     Document Type: Article

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