-
1
-
-
84893513577
-
International ERS/ATS guidelines on definition, evaluation and treatment of severe asthma
-
Chung K.F., Wenzel S.E., Brozek J.L., Bush A., Castro M., Sterk P.J., et al. International ERS/ATS guidelines on definition, evaluation and treatment of severe asthma. Eur Respir J. 2014, 43:343-373.
-
(2014)
Eur Respir J.
, vol.43
, pp. 343-373
-
-
Chung, K.F.1
Wenzel, S.E.2
Brozek, J.L.3
Bush, A.4
Castro, M.5
Sterk, P.J.6
-
2
-
-
84860679595
-
Asthma phenotypes: the evolution from clinical to molecular approaches
-
Wenzel S.E. Asthma phenotypes: the evolution from clinical to molecular approaches. Nat Med. 2012, 18:716-725.
-
(2012)
Nat Med.
, vol.18
, pp. 716-725
-
-
Wenzel, S.E.1
-
3
-
-
84871189640
-
Induced sputum in asthma: diagnostic and therapeutic implications
-
Davies A.R., Hancox R.J. Induced sputum in asthma: diagnostic and therapeutic implications. Curr Opin Pulm Med. 2013, 19:60-65.
-
(2013)
Curr Opin Pulm Med.
, vol.19
, pp. 60-65
-
-
Davies, A.R.1
Hancox, R.J.2
-
4
-
-
77956444329
-
-
Disponible en:
-
Guía Española para el Manejo del Asma (GEMA 2009). Arch Bronconeumol. 2009;45 (Suppl 2):1-35. Disponible en: . http://www.gemasma.com/.
-
(2009)
Arch Bronconeumol.
, vol.45
, pp. 1-35
-
-
-
5
-
-
33645101537
-
Inflammatory subtypes in asthma: assessment and identification using induced sputum
-
Simpson J.L., Scott R., Boyle M.J., Gibson P.G. Inflammatory subtypes in asthma: assessment and identification using induced sputum. Respirology. 2006, 11:54-61.
-
(2006)
Respirology.
, vol.11
, pp. 54-61
-
-
Simpson, J.L.1
Scott, R.2
Boyle, M.J.3
Gibson, P.G.4
-
6
-
-
0033606539
-
Non-eosinophilic corticosteroid unresponsive asthma
-
Pavord I.D., Brightling C.E., Woltmann G., Wardlaw A.J. Non-eosinophilic corticosteroid unresponsive asthma. Lancet. 1999, 353:2213-2214.
-
(1999)
Lancet.
, vol.353
, pp. 2213-2214
-
-
Pavord, I.D.1
Brightling, C.E.2
Woltmann, G.3
Wardlaw, A.J.4
-
7
-
-
36749095585
-
Pathological features and inhaled corticosteroid response of eosinophilic and non-eosinophilic asthma
-
Berry M., Morgan A., Shaw D.E., Parker D., Green R., Brightling C., et al. Pathological features and inhaled corticosteroid response of eosinophilic and non-eosinophilic asthma. Thorax. 2007, 62:1043-1049.
-
(2007)
Thorax
, vol.62
, pp. 1043-1049
-
-
Berry, M.1
Morgan, A.2
Shaw, D.E.3
Parker, D.4
Green, R.5
Brightling, C.6
-
8
-
-
38348998987
-
Clarithromycin targets neutrophilic airway inflammation in refractory asthma
-
Simpson J.L., Powell H., Boyle M.J., Scott R.J., Gibson P.G. Clarithromycin targets neutrophilic airway inflammation in refractory asthma. Am J Respir Crit Care Med. 2008, 177:148-155.
-
(2008)
Am J Respir Crit Care Med.
, vol.177
, pp. 148-155
-
-
Simpson, J.L.1
Powell, H.2
Boyle, M.J.3
Scott, R.J.4
Gibson, P.G.5
-
9
-
-
49649102385
-
Tiotropium bromide is effective for severe asthma with noneosinophilic phenotype
-
Iwamoto H., Yokoyama A., Shiota N., Shoda H., Haruta Y., Hattori N., et al. Tiotropium bromide is effective for severe asthma with noneosinophilic phenotype. Eur Respir J. 2008, 31:1379-1380.
-
(2008)
Eur Respir J.
, vol.31
, pp. 1379-1380
-
-
Iwamoto, H.1
Yokoyama, A.2
Shiota, N.3
Shoda, H.4
Haruta, Y.5
Hattori, N.6
-
10
-
-
0029799037
-
Alveolar tissue inflammation in asthma
-
Kraft M., Djukanovic R., Wilson S., Holgate S.T., Martin R.J. Alveolar tissue inflammation in asthma. Am J Respir Crit Care Med. 1996, 154:1505-1510.
-
(1996)
Am J Respir Crit Care Med.
, vol.154
, pp. 1505-1510
-
-
Kraft, M.1
Djukanovic, R.2
Wilson, S.3
Holgate, S.T.4
Martin, R.J.5
-
11
-
-
0036718499
-
Clinical applications of assessment of airway inflammation using induced sputum
-
Pavord I.D., Sterk P.J., Hargreave F.E., Kips J.C., Inman M.D., Louis R., et al. Clinical applications of assessment of airway inflammation using induced sputum. Eur Respir J Suppl. 2002, 37:40s-43s.
-
(2002)
Eur Respir J Suppl.
, vol.37
, pp. 40s-43s
-
-
Pavord, I.D.1
Sterk, P.J.2
Hargreave, F.E.3
Kips, J.C.4
Inman, M.D.5
Louis, R.6
-
12
-
-
0033954741
-
The relationship between airways inflammation and asthma severity
-
Louis R., Lau L.C., Bron A.O., Roldaan A.C., Radermecker M., Djukanovic R. The relationship between airways inflammation and asthma severity. Am J Respir Crit Care Med. 2000, 161:9-16.
-
(2000)
Am J Respir Crit Care Med.
, vol.161
, pp. 9-16
-
-
Louis, R.1
Lau, L.C.2
Bron, A.O.3
Roldaan, A.C.4
Radermecker, M.5
Djukanovic, R.6
-
13
-
-
77951666051
-
Variability of sputum inflammatory cells in asthmatic patients receiving corticosteroid therapy: A prospective study using multiple samples
-
Al-Samri M.T., Benedetti A., Prefontaine D., Olivenstein R., Lemiere C., Nair P., et al. Variability of sputum inflammatory cells in asthmatic patients receiving corticosteroid therapy: A prospective study using multiple samples. J Allergy Clin Immunol. 2010, 125:1161-1163.
-
(2010)
J Allergy Clin Immunol.
, vol.125
, pp. 1161-1163
-
-
Al-Samri, M.T.1
Benedetti, A.2
Prefontaine, D.3
Olivenstein, R.4
Lemiere, C.5
Nair, P.6
-
14
-
-
84864022085
-
Sputum inflammatory phenotypes are not stable in children with asthma
-
Fleming L., Tsartsali L., Wilson N., Regamey N., Bush A. Sputum inflammatory phenotypes are not stable in children with asthma. Thorax. 2012, 67:675-681.
-
(2012)
Thorax
, vol.67
, pp. 675-681
-
-
Fleming, L.1
Tsartsali, L.2
Wilson, N.3
Regamey, N.4
Bush, A.5
-
15
-
-
69349091073
-
Consistency of sputum eosinophilia in difficult-to-treat asthma: a 5-year follow-up study
-
617.
-
Van Veen I.H., Ten B.A., Gauw S.A., Sterk P.J., Rabe K.F., Bel E.H. Consistency of sputum eosinophilia in difficult-to-treat asthma: a 5-year follow-up study. J Allergy Clin Immunol. 2009, 124:615-617. 617.
-
(2009)
J Allergy Clin Immunol.
, vol.124
, pp. 615-617
-
-
Van Veen, I.H.1
Ten, B.A.2
Gauw, S.A.3
Sterk, P.J.4
Rabe, K.F.5
Bel, E.H.6
-
16
-
-
34247485053
-
Noneosinophilic asthma: a distinct clinical and pathologic phenotype
-
Haldar P., Pavord I.D. Noneosinophilic asthma: a distinct clinical and pathologic phenotype. J Allergy Clin Immunol. 2007, 119:1043-1052.
-
(2007)
J Allergy Clin Immunol.
, vol.119
, pp. 1043-1052
-
-
Haldar, P.1
Pavord, I.D.2
-
17
-
-
0037202790
-
Asthma exacerbations and sputum eosinophil counts: a randomised controlled trial
-
Green R.H., Brightling C.E., McKenna S., Hargadon B., Parker D., Bradding P., et al. Asthma exacerbations and sputum eosinophil counts: a randomised controlled trial. Lancet. 2002, 360:1715-1721.
-
(2002)
Lancet.
, vol.360
, pp. 1715-1721
-
-
Green, R.H.1
Brightling, C.E.2
McKenna, S.3
Hargadon, B.4
Parker, D.5
Bradding, P.6
-
18
-
-
46149087663
-
-
[consultado 15 Sep 2014]. Disponible en:
-
Global Strategy for Asthma Management and Prevention. Global Initiative for Asthma (GINA) 2014. [consultado 15 Sep 2014]. Disponible en: . http://www.ginasthma.org/.
-
(2014)
Global Initiative for Asthma (GINA)
-
-
-
19
-
-
37549042465
-
Validation of the Spanish version of the Asthma Control Test (ACT)
-
Vega J.M., Badia X., Badiola C., Lopez-Vina A., Olaguibel J.M., Picado C., et al. Validation of the Spanish version of the Asthma Control Test (ACT). J Asthma. 2007, 44:867-872.
-
(2007)
J Asthma.
, vol.44
, pp. 867-872
-
-
Vega, J.M.1
Badia, X.2
Badiola, C.3
Lopez-Vina, A.4
Olaguibel, J.M.5
Picado, C.6
-
20
-
-
67649805319
-
An official American Thoracic Society/European Respiratory Society statement: asthma control and exacerbations: standardizing endpoints for clinical asthma trials and clinical practice
-
Reddel H.K., Taylor D.R., Bateman E.D., Boulet L.P., Boushey H.A., Busse W.W., et al. An official American Thoracic Society/European Respiratory Society statement: asthma control and exacerbations: standardizing endpoints for clinical asthma trials and clinical practice. Am J Respir Crit Care Med. 2009, 180:59-99.
-
(2009)
Am J Respir Crit Care Med.
, vol.180
, pp. 59-99
-
-
Reddel, H.K.1
Taylor, D.R.2
Bateman, E.D.3
Boulet, L.P.4
Boushey, H.A.5
Busse, W.W.6
-
21
-
-
40949106078
-
Allergy diagnostic testing: an updated practice parameter
-
Bernstein I.L., Li J.T., Bernstein D.I., Hamilton R., Spector S.L., Tan R., et al. Allergy diagnostic testing: an updated practice parameter. Ann Allergy Asthma Immunol. 2008, 100(3 Suppl 3):S1-S148.
-
(2008)
Ann Allergy Asthma Immunol.
, vol.100
, Issue.3
, pp. S1-S148
-
-
Bernstein, I.L.1
Li, J.T.2
Bernstein, D.I.3
Hamilton, R.4
Spector, S.L.5
Tan, R.6
-
22
-
-
84883446043
-
Spirometry. Spanish Society of Pulmonology and Thoracic Surgery (SEPAR)
-
Garcia-Rio F., Calle M., Burgos F., Casan P., Del C.F., Galdiz J.B., et al. Spirometry. Spanish Society of Pulmonology and Thoracic Surgery (SEPAR). Arch Bronconeumol. 2013, 49:388-401.
-
(2013)
Arch Bronconeumol.
, vol.49
, pp. 388-401
-
-
Garcia-Rio, F.1
Calle, M.2
Burgos, F.3
Casan, P.4
Del, C.F.5
Galdiz, J.B.6
-
23
-
-
0022654287
-
Spirometric reference values from a Mediterranean population
-
Roca J., Sanchis J., Agusti-Vidal A., Segarra F., Navajas D., Rodriguez-Roisin R., et al. Spirometric reference values from a Mediterranean population. Bull Eur Physiopathol Respir. 1986, 22:217-224.
-
(1986)
Bull Eur Physiopathol Respir.
, vol.22
, pp. 217-224
-
-
Roca, J.1
Sanchis, J.2
Agusti-Vidal, A.3
Segarra, F.4
Navajas, D.5
Rodriguez-Roisin, R.6
-
24
-
-
17644363081
-
ATS/ERS recommendations for standardized procedures for the online and offline measurement of exhaled lower respiratory nitric oxide and nasal nitric oxide, 2005
-
ATS/ERS recommendations for standardized procedures for the online and offline measurement of exhaled lower respiratory nitric oxide and nasal nitric oxide, 2005. Am J Respir Crit Care Med. 2005, 171:912-930.
-
(2005)
Am J Respir Crit Care Med.
, vol.171
, pp. 912-930
-
-
-
25
-
-
80052438246
-
An official ATS clinical practice guideline: interpretation of exhaled nitric oxide levels (FENO) for clinical applications
-
Dweik R.A., Boggs P.B., Erzurum S.C., Irvin C.G., Leigh M.W., Lundberg J.O., et al. An official ATS clinical practice guideline: interpretation of exhaled nitric oxide levels (FENO) for clinical applications. Am J Respir Crit Care Med. 2011, 184:602-615.
-
(2011)
Am J Respir Crit Care Med.
, vol.184
, pp. 602-615
-
-
Dweik, R.A.1
Boggs, P.B.2
Erzurum, S.C.3
Irvin, C.G.4
Leigh, M.W.5
Lundberg, J.O.6
-
26
-
-
0029759171
-
Indices of airway inflammation in induced sputum: reproducibility and validity of cell and fluid-phase measurements
-
Pizzichini E., Pizzichini M.M., Efthimiadis A., Evans S., Morris M.M., Squillace D., et al. Indices of airway inflammation in induced sputum: reproducibility and validity of cell and fluid-phase measurements. Am J Respir Crit Care Med. 1996, 154:308-317.
-
(1996)
Am J Respir Crit Care Med.
, vol.154
, pp. 308-317
-
-
Pizzichini, E.1
Pizzichini, M.M.2
Efthimiadis, A.3
Evans, S.4
Morris, M.M.5
Squillace, D.6
-
27
-
-
84858273561
-
A large subgroup of mild-to-moderate asthma is persistently noneosinophilic
-
McGrath K.W., Icitovic N., Boushey H.A., Lazarus S.C., Sutherland E.R., Chinchilli V.M., et al. A large subgroup of mild-to-moderate asthma is persistently noneosinophilic. Am J Respir Crit Care Med. 2012, 185:612-619.
-
(2012)
Am J Respir Crit Care Med.
, vol.185
, pp. 612-619
-
-
McGrath, K.W.1
Icitovic, N.2
Boushey, H.A.3
Lazarus, S.C.4
Sutherland, E.R.5
Chinchilli, V.M.6
-
28
-
-
34548247694
-
Changing pattern of sputum cell counts during successive exacerbations of airway disease
-
D'silva L., Cook R.J., Allen C.J., Hargreave F.E., Parameswaran K. Changing pattern of sputum cell counts during successive exacerbations of airway disease. Respir Med. 2007, 101:2217-2220.
-
(2007)
Respir Med.
, vol.101
, pp. 2217-2220
-
-
D'silva, L.1
Cook, R.J.2
Allen, C.J.3
Hargreave, F.E.4
Parameswaran, K.5
-
29
-
-
84905819945
-
Stability of phenotypes defined by physiological variables and biomarkers in adults with asthma
-
Kupczyk M., Dahlén B., Sterk P.J., Nizankowska-Mogilnicka E., Papi A., Bel E.H., et al. Stability of phenotypes defined by physiological variables and biomarkers in adults with asthma. Allergy. 2014, 69:1198-1204.
-
(2014)
Allergy.
, vol.69
, pp. 1198-1204
-
-
Kupczyk, M.1
Dahlén, B.2
Sterk, P.J.3
Nizankowska-Mogilnicka, E.4
Papi, A.5
Bel, E.H.6
-
30
-
-
84864022205
-
Stability of inflammatory phenotypes in asthma
-
Green R.H., Pavord I. Stability of inflammatory phenotypes in asthma. Thorax. 2012, 67:665-667.
-
(2012)
Thorax
, vol.67
, pp. 665-667
-
-
Green, R.H.1
Pavord, I.2
-
31
-
-
84874196355
-
Distribution of sputum cellular phenotype in a large asthma cohort: predicting factors for eosinophilic vs neutrophilic inflammation
-
Schleich F.N., Manise M., Sele J., Henket M., Seidel L., Louis R. Distribution of sputum cellular phenotype in a large asthma cohort: predicting factors for eosinophilic vs neutrophilic inflammation. BMC Pulm Med. 2013, 13:11.
-
(2013)
BMC Pulm Med.
, vol.13
, pp. 11
-
-
Schleich, F.N.1
Manise, M.2
Sele, J.3
Henket, M.4
Seidel, L.5
Louis, R.6
-
32
-
-
0035684297
-
Smoking and airway inflammation in patients with mild asthma
-
Chalmers G.W., MacLeod K.J., Thomson L., Little S.A., McSharry C., Thomson N.C. Smoking and airway inflammation in patients with mild asthma. Chest. 2001, 120:1917-1922.
-
(2001)
Chest.
, vol.120
, pp. 1917-1922
-
-
Chalmers, G.W.1
MacLeod, K.J.2
Thomson, L.3
Little, S.A.4
McSharry, C.5
Thomson, N.C.6
-
33
-
-
58149214006
-
Asthma in smokers: challenges and opportunities
-
Thomson N.C., Chaudhuri R. Asthma in smokers: challenges and opportunities. Curr Opin Pulm Med. 2009, 15:39-45.
-
(2009)
Curr Opin Pulm Med.
, vol.15
, pp. 39-45
-
-
Thomson, N.C.1
Chaudhuri, R.2
-
34
-
-
0036153548
-
Neutrophil degranulation and cell lysis is associated with clinical severity in virus-induced asthma
-
Wark P.A., Johnston S.L., Moric I., Simpson J.L., Hensley M.J., Gibson P.G. Neutrophil degranulation and cell lysis is associated with clinical severity in virus-induced asthma. Eur Respir J. 2002, 19:68-75.
-
(2002)
Eur Respir J.
, vol.19
, pp. 68-75
-
-
Wark, P.A.1
Johnston, S.L.2
Moric, I.3
Simpson, J.L.4
Hensley, M.J.5
Gibson, P.G.6
-
35
-
-
33846270333
-
Bronchiolitis to asthma: a review and call for studies of gene-virus interactions in asthma causation
-
Singh A.M., Moore P.E., Gern J.E., Lemanske R.F., Hartert T.V. Bronchiolitis to asthma: a review and call for studies of gene-virus interactions in asthma causation. Am J Respir Crit Care Med. 2007, 175:108-119.
-
(2007)
Am J Respir Crit Care Med.
, vol.175
, pp. 108-119
-
-
Singh, A.M.1
Moore, P.E.2
Gern, J.E.3
Lemanske, R.F.4
Hartert, T.V.5
-
36
-
-
0030949914
-
Sputum in severe exacerbations of asthma: kinetics of inflammatory indices after prednisone treatment
-
Pizzichini M.M., Pizzichini E., Clelland L., Efthimiadis A., Mahony J., Dolovich J., et al. Sputum in severe exacerbations of asthma: kinetics of inflammatory indices after prednisone treatment. Am J Respir Crit Care Med. 1997, 155:1501-1508.
-
(1997)
Am J Respir Crit Care Med.
, vol.155
, pp. 1501-1508
-
-
Pizzichini, M.M.1
Pizzichini, E.2
Clelland, L.3
Efthimiadis, A.4
Mahony, J.5
Dolovich, J.6
-
37
-
-
0033060321
-
Effect of differing doses of inhaled budesonide on markers of airway inflammation in patients with mild asthma
-
Jatakanon A., Kharitonov S., Lim S., Barnes P.J. Effect of differing doses of inhaled budesonide on markers of airway inflammation in patients with mild asthma. Thorax. 1999, 54:108-114.
-
(1999)
Thorax
, vol.54
, pp. 108-114
-
-
Jatakanon, A.1
Kharitonov, S.2
Lim, S.3
Barnes, P.J.4
-
38
-
-
84857429187
-
A systematic review and meta-analysis: tailoring asthma treatment on eosinophilic markers (exhaled nitric oxide or sputum eosinophils)
-
Petsky H.L., Cates C.J., Lasserson T.J., Li A.M., Turner C., Kynaston J.A., et al. A systematic review and meta-analysis: tailoring asthma treatment on eosinophilic markers (exhaled nitric oxide or sputum eosinophils). Thorax. 2012, 67:199-208.
-
(2012)
Thorax
, vol.67
, pp. 199-208
-
-
Petsky, H.L.1
Cates, C.J.2
Lasserson, T.J.3
Li, A.M.4
Turner, C.5
Kynaston, J.A.6
-
39
-
-
0032922825
-
Effect of inhaled steroids on airway hyperresponsiveness, sputum eosinophils, and exhaled nitric oxide levels in patients with asthma
-
Van Rensen E.L., Straathof K.C., Veselic-Charvat M.A., Zwinderman A.H., Bel E.H., Sterk P.J. Effect of inhaled steroids on airway hyperresponsiveness, sputum eosinophils, and exhaled nitric oxide levels in patients with asthma. Thorax. 1999, 54:403-408.
-
(1999)
Thorax
, vol.54
, pp. 403-408
-
-
Van Rensen, E.L.1
Straathof, K.C.2
Veselic-Charvat, M.A.3
Zwinderman, A.H.4
Bel, E.H.5
Sterk, P.J.6
-
40
-
-
77951979415
-
Effects of steroid therapy on inflammatory cell subtypes in asthma
-
Cowan D.C., Cowan J.O., Palmay R., Williamson A., Taylor D.R. Effects of steroid therapy on inflammatory cell subtypes in asthma. Thorax. 2010, 65:384-390.
-
(2010)
Thorax
, vol.65
, pp. 384-390
-
-
Cowan, D.C.1
Cowan, J.O.2
Palmay, R.3
Williamson, A.4
Taylor, D.R.5
|