메뉴 건너뛰기




Volumn 54, Issue 2, 1999, Pages 108-114

Effect of differing doses of inhaled budesonide on markers of airway inflammation in patients with mild asthma

Author keywords

Airway inflammation; Asthma; Inhaled corticosteroids

Indexed keywords

ANTIASTHMATIC AGENT; BUDESONIDE; METHACHOLINE; NITRIC OXIDE;

EID: 0033060321     PISSN: 00406376     EISSN: None     Source Type: Journal    
DOI: 10.1136/thx.54.2.108     Document Type: Article
Times cited : (240)

References (37)
  • 2
    • 0002776555 scopus 로고    scopus 로고
    • The british guidelines on asthma management
    • 2 British Thoracic Society. The British guidelines on asthma management. Thorax 1997;52(Suppl 1):S1-21.
    • (1997) Thorax , vol.52 , Issue.SUPPL. 1
  • 3
    • 0030010572 scopus 로고
    • Relationship between the inflammatory infiltrate in bronchial biopsy specimens and clinical severity of asthma in patients treated with inhaled steroids
    • 3 Sont JK, Han J, van Krieken JM, et al. Relationship between the inflammatory infiltrate in bronchial biopsy specimens and clinical severity of asthma in patients treated with inhaled steroids. Thorax 1096;51:496-502.
    • (1096) Thorax , vol.51 , pp. 496-502
    • Sont, J.K.1    Han, J.2    Van Krieken, J.M.3
  • 4
    • 0028023279 scopus 로고
    • Effects of reducing or discontinuing inhaled budesonide in patients with mild asthma
    • 4 Haahtela T, Jarvinen M, Kava T, et al. Effects of reducing or discontinuing inhaled budesonide in patients with mild asthma. N Engl J Med 1994;331:700-5.
    • (1994) N Engl J Med , vol.331 , pp. 700-705
    • Haahtela, T.1    Jarvinen, M.2    Kava, T.3
  • 5
    • 0028053173 scopus 로고
    • Increased nitric oxide in exhaled air of asthmatic patients
    • 5 Kharitonov SA, Yates D, Robbins RA, et al. Increased nitric oxide in exhaled air of asthmatic patients. Lancet 1994;343: 133-5.
    • (1994) Lancet , vol.343 , pp. 133-135
    • Kharitonov, S.A.1    Yates, D.2    Robbins, R.A.3
  • 6
    • 0024473570 scopus 로고
    • Cellular characteristics of sputum from patients with asthma and chronic bronchitis
    • 6 Gibson PG, Girgis Gabardo A, Morris, et al. Cellular characteristics of sputum from patients with asthma and chronic bronchitis. Thorax 1989;44:693-9.
    • (1989) Thorax , vol.44 , pp. 693-699
    • Gibson, P.G.1    Girgis Gabardo, A.2    Morris3
  • 7
    • 0030022873 scopus 로고    scopus 로고
    • Inhaled glucocorticoids decrease nitric oxide in exhaled air of asthmatic patients
    • 7 Kharitonov SA, Yates DH, Barnes PJ. Inhaled glucocorticoids decrease nitric oxide in exhaled air of asthmatic patients. Am J Respir Crit Care Med 1996;153;454-7.
    • (1996) Am J Respir Crit Care Med , vol.153 , pp. 454-457
    • Kharitonov, S.A.1    Yates, D.H.2    Barnes, P.J.3
  • 8
    • 0031045482 scopus 로고    scopus 로고
    • Effects of inhaled and oral glucocorticoids on inflammatory indices in asthma and COPD
    • 8 Keatings VM, Jatakanon A, Worsdell YM, et al. Effects of inhaled and oral glucocorticoids on inflammatory indices in asthma and COPD. Am J Respir Crit Care Med 1997;155:542-8.
    • (1997) Am J Respir Crit Care Med , vol.155 , pp. 542-548
    • Keatings, V.M.1    Jatakanon, A.2    Worsdell, Y.M.3
  • 9
    • 0027939414 scopus 로고
    • Analysis of induced sputum to examine the effects of prednisone on airway inflammation in asthmatic subjects
    • 9 Claman DM, Boushey HA, Liu J, et al. Analysis of induced sputum to examine the effects of prednisone on airway inflammation in asthmatic subjects. J Allergy Clin Immunol 1994;94:861-9.
    • (1994) J Allergy Clin Immunol , vol.94 , pp. 861-869
    • Claman, D.M.1    Boushey, H.A.2    Liu, J.3
  • 10
    • 0028182973 scopus 로고
    • Pulmicort turbohaler once daily as initial prophylactic therapy for asthma
    • 10 Jones AH, Langdon CG, Lee PS, et al. Pulmicort Turbohaler once daily as initial prophylactic therapy for asthma. Respir Med 1994;88:293-9.
    • (1994) Respir Med , vol.88 , pp. 293-299
    • Jones, A.H.1    Langdon, C.G.2    Lee, P.S.3
  • 11
    • 0016747809 scopus 로고
    • Standardization of bronchial inhalation challenge procedures
    • 11 Chai H, Farr RS, Froehlich LA, et al. Standardization of bronchial inhalation challenge procedures. J Allergy Clin Immunol 1975;56:323-7.
    • (1975) J Allergy Clin Immunol , vol.56 , pp. 323-327
    • Chai, H.1    Farr, R.S.2    Froehlich, L.A.3
  • 12
    • 0029934167 scopus 로고    scopus 로고
    • Increased exhaled nitric oxide in asthma is mainly derived from the lower respiratory tract
    • 12 Kharitonov SA, Chung KF, Evans D, et al. Increased exhaled nitric oxide in asthma is mainly derived from the lower respiratory tract. Am J Respir Crit Care Med 1996;153:1773-80.
    • (1996) Am J Respir Crit Care Med , vol.153 , pp. 1773-1780
    • Kharitonov, S.A.1    Chung, K.F.2    Evans, D.3
  • 13
    • 0031900026 scopus 로고    scopus 로고
    • Correlation between exhaled nitric oxide, sputum eosinophils, and methacholine responsiveness in patients with mild asthma
    • 13 Jatakanon A, Lim S, Kharitonov SA, et al. Correlation between exhaled nitric oxide, sputum eosinophils, and methacholine responsiveness in patients with mild asthma. Thorax 1998;53:91-5.
    • (1998) Thorax , vol.53 , pp. 91-95
    • Jatakanon, A.1    Lim, S.2    Kharitonov, S.A.3
  • 16
    • 0029854203 scopus 로고    scopus 로고
    • Comparison of two methods of collecting induced sputum in asthmatic subjects
    • 16 Gershman NH, Wong HH, Liu JT, et al. Comparison of two methods of collecting induced sputum in asthmatic subjects. Eur Respir J 1996;9:2448-53.
    • (1996) Eur Respir J , vol.9 , pp. 2448-2453
    • Gershman, N.H.1    Wong, H.H.2    Liu, J.T.3
  • 17
    • 0010526385 scopus 로고    scopus 로고
    • Repeatability of cellular and soluble markers of inflammation in induced sputum from patients with asthma
    • 17 in't Veen JC, de Gouw HW, Smits HH, et al. Repeatability of cellular and soluble markers of inflammation in induced sputum from patients with asthma. Eur Respir J 1996;9: 2441-7.
    • (1996) Eur Respir J , vol.9 , pp. 2441-2447
    • In't Veen, J.C.1    De Gouw, H.W.2    Smits, H.H.3
  • 18
    • 0029759171 scopus 로고    scopus 로고
    • Indices of airway inflammation in induced sputum: Reproducibility and validity of cell and fluid-phase measurements
    • 18 Pizzichini E, Pizzichini MM, Efthimiadis A, et al. Indices of airway inflammation in induced sputum: reproducibility and validity of cell and fluid-phase measurements. Am J Respir Crit Care Med 1996;154:308-17.
    • (1996) Am J Respir Crit Care Med , vol.154 , pp. 308-317
    • Pizzichini, E.1    Pizzichini, M.M.2    Efthimiadis, A.3
  • 19
    • 0030903524 scopus 로고    scopus 로고
    • Measuring airway inflammation in asthma: Eosinophils and eosinophilic cationic protein in induced sputum compared with peripheral blood
    • 19 Pizzichini E, Pizzichini MM, Efthimiadis A, et al. Measuring airway inflammation in asthma: eosinophils and eosinophilic cationic protein in induced sputum compared with peripheral blood. J Allergy Clin Immunol 1997;99:539 44.
    • (1997) J Allergy Clin Immunol , vol.99 , pp. 539-544
    • Pizzichini, E.1    Pizzichini, M.M.2    Efthimiadis, A.3
  • 20
    • 0026736590 scopus 로고
    • A research method to induce and examine a mild exacerbation of asthma by withdrawal of inhaled corticosteroid
    • 20 Gibson PG, Wong BJ, Hepperle MJ, et al. A research method to induce and examine a mild exacerbation of asthma by withdrawal of inhaled corticosteroid. Clin Exp Allergy 1992;22:525-32.
    • (1992) Clin Exp Allergy , vol.22 , pp. 525-532
    • Gibson, P.G.1    Wong, B.J.2    Hepperle, M.J.3
  • 21
    • 0030949914 scopus 로고    scopus 로고
    • Sputum in severe exacerbations of asthma: Kinetics of inflammatory indices after prednisone treatment
    • 21 Pizzichini MM, Pizzichini E, Clelland L, et al. Sputum in severe exacerbations of asthma: kinetics of inflammatory indices after prednisone treatment. Am J Respir Crit Care Med 1997;155:1501-8.
    • (1997) Am J Respir Crit Care Med , vol.155 , pp. 1501-1508
    • Pizzichini, M.M.1    Pizzichini, E.2    Clelland, L.3
  • 22
    • 0026075046 scopus 로고
    • Glucocorticoids inhibit eosinophil responses to granulocyte-macrophage colony-stimulating factor
    • 22 Lamas AM, Leon OG, Schleimer RP. Glucocorticoids inhibit eosinophil responses to granulocyte-macrophage colony-stimulating factor. J Immunol 1991;147:254-9.
    • (1991) J Immunol , vol.147 , pp. 254-259
    • Lamas, A.M.1    Leon, O.G.2    Schleimer, R.P.3
  • 23
    • 0025841768 scopus 로고
    • Glucocorticoids inhibit cytokine-mediated eosinophil survival
    • 23 Wallen N, Kita H, Weiler D, et al. Glucocorticoids inhibit cytokine-mediated eosinophil survival. J Immunol 1991; 147:3490-5.
    • (1991) J Immunol , vol.147 , pp. 3490-3495
    • Wallen, N.1    Kita, H.2    Weiler, D.3
  • 24
    • 0026568888 scopus 로고
    • Glucocorticoids inhibit granulocyte-macrophage colony-stimulating factor-1 and interleukin-5 enhanced in vitro survival of human eosinophils
    • 24 Hallsworth MP, Litchfield TM, Lee TH. Glucocorticoids inhibit granulocyte-macrophage colony-stimulating factor-1 and interleukin-5 enhanced in vitro survival of human eosinophils. Immunology 1992;75:382-5.
    • (1992) Immunology , vol.75 , pp. 382-385
    • Hallsworth, M.P.1    Litchfield, T.M.2    Lee, T.H.3
  • 25
    • 0021016319 scopus 로고
    • A. Sputum and blood eosinophils during corticosteroid treatment of acute exacerbations of asthma
    • 25 Baigelman W, Chodosh S, Pizzuto D, et al. A. Sputum and blood eosinophils during corticosteroid treatment of acute exacerbations of asthma. Am J Med 1983;75:929-36.
    • (1983) Am J Med , vol.75 , pp. 929-936
    • Baigelman, W.1    Chodosh, S.2    Pizzuto, D.3
  • 26
    • 0029299370 scopus 로고
    • Peripheral blood CD4 but not CD8 T-lymphocytes in patients with exacerbation of asthma transcribe and translate messenger RNA encoding cytokines which prolong eosinophil survival in the context of a Th2-type pattern: Effect of glucocorticoid therapy
    • 26 Corrigan CJ, Hamid Q, North J, et al. Peripheral blood CD4 but not CD8 T-lymphocytes in patients with exacerbation of asthma transcribe and translate messenger RNA encoding cytokines which prolong eosinophil survival in the context of a Th2-type pattern: effect of glucocorticoid therapy. Am J Respir Cell Mol Biol 1995;12:567-78.
    • (1995) Am J Respir Cell Mol Biol , vol.12 , pp. 567-578
    • Corrigan, C.J.1    Hamid, Q.2    North, J.3
  • 27
    • 0031958895 scopus 로고    scopus 로고
    • Budesonide delivered by turbuhaler is effective in a dose-dependent fashion when used in the treatment of adult patients with chronic asthma
    • 27 Busse WW, Chervinsky P, Condemi J, et al. Budesonide delivered by Turbuhaler is effective in a dose-dependent fashion when used in the treatment of adult patients with chronic asthma. J Allergy Clin Immunol 1998;101:457-63.
    • (1998) J Allergy Clin Immunol , vol.101 , pp. 457-463
    • Busse, W.W.1    Chervinsky, P.2    Condemi, J.3
  • 28
    • 0001772876 scopus 로고
    • Once daily budesonide: Effective control of moderately severe asthma with 800 μg once daily inhaled via turbohaler when compared with 400 μg twice daily
    • 28 Campbell LM, Gunn SD, Sweeney D, et al. Once daily budesonide: effective control of moderately severe asthma with 800 μg once daily inhaled via Turbohaler when compared with 400 μg twice daily. Eur J Clin Res 1995;7:1-14.
    • (1995) Eur J Clin Res , vol.7 , pp. 1-14
    • Campbell, L.M.1    Gunn, S.D.2    Sweeney, D.3
  • 29
    • 0025650904 scopus 로고
    • Long-term effects of budesonide on airway responsiveness and clinical asthma severity in inhaled steroid-dependent asthmatics
    • 29 Juniper EF, Kline PA, Vanzieleghem MA, et al. Long-term effects of budesonide on airway responsiveness and clinical asthma severity in inhaled steroid-dependent asthmatics. Eur Respir J 1990;3:1122-7.
    • (1990) Eur Respir J , vol.3 , pp. 1122-1127
    • Juniper, E.F.1    Kline, P.A.2    Vanzieleghem, M.A.3
  • 30
    • 0024309119 scopus 로고
    • New concepts in the pathogenesis of bronchial hyperresponsiveness and asthma
    • 30 Barnes PJ. New concepts in the pathogenesis of bronchial hyperresponsiveness and asthma. J Allergy Clin Immunol 1989;83:1013-26.
    • (1989) J Allergy Clin Immunol , vol.83 , pp. 1013-1026
    • Barnes, P.J.1
  • 31
    • 0025763928 scopus 로고
    • Time course of change in bronchial reactivity with an inhaled corticosteroid in asthma
    • 31 Vathenen AS, Knox AJ, Wisniewski A, et al. Time course of change in bronchial reactivity with an inhaled corticosteroid in asthma. Am Rev Respir Dis 1991;143:1317-21.
    • (1991) Am Rev Respir Dis , vol.143 , pp. 1317-1321
    • Vathenen, A.S.1    Knox, A.J.2    Wisniewski, A.3
  • 32
    • 0025036349 scopus 로고
    • Effect of long-term treatment with an inhaled corticosteroid (budesonide) on airway hyperresponsiveness and clinical asthma in nonsteroid-dependent asthmatics
    • 32 Juniper EF, Kline PA, Vanzieleghem MA, et al. Effect of long-term treatment with an inhaled corticosteroid (budesonide) on airway hyperresponsiveness and clinical asthma in nonsteroid-dependent asthmatics. Am Rev Respir Dis 1990;142:832-6.
    • (1990) Am Rev Respir Dis , vol.142 , pp. 832-836
    • Juniper, E.F.1    Kline, P.A.2    Vanzieleghem, M.A.3
  • 33
    • 0026788313 scopus 로고
    • Effects of 22 months of treatment with inhaled corticosteroids and or beta-2-agonists on lung function, airway responsiveness, and symptoms in children with asthma
    • The Dutch Chronic Non-specific Lung Disease Study Group
    • 33 van Essen Zandvliet EE, Hughes MD, et al. Effects of 22 months of treatment with inhaled corticosteroids and or beta-2-agonists on lung function, airway responsiveness, and symptoms in children with asthma The Dutch Chronic Non-specific Lung Disease Study Group. Am Rev Respir Dis 1992;146:547-54.
    • (1992) Am Rev Respir Dis , vol.146 , pp. 547-554
    • Van Essen Zandvliet, E.E.1    Hughes, M.D.2
  • 34
    • 0026474682 scopus 로고
    • A comparison of bronchodilator therapy with or without inhaled corticosteroid therapy for obstructive airways disease
    • Dutch Chronic Non-Specific Lung Disease Study Group
    • 34 Kerstjens HA, Brand PL, Hughes MD, et al. A comparison of bronchodilator therapy with or without inhaled corticosteroid therapy for obstructive airways disease. Dutch Chronic Non-Specific Lung Disease Study Group. N Engl J Med 1992;327:1413-9.
    • (1992) N Engl J Med , vol.327 , pp. 1413-1419
    • Kerstjens, H.A.1    Brand, P.L.2    Hughes, M.D.3
  • 35
    • 0023872227 scopus 로고
    • Dosage and time effects of inhaled budesonide on bronchial hyperreactivity
    • 35 Kraan J, Koeter GH, van der Mark ?, et al. Dosage and time effects of inhaled budesonide on bronchial hyperreactivity. Am Rev Respir Dis 1988;137:44-8.
    • (1988) Am Rev Respir Dis , vol.137 , pp. 44-48
    • Kraan, J.1    Koeter, G.H.2    Van Der Mark3
  • 36
    • 0029090365 scopus 로고
    • Effect of high dose inhaled fluticasone propionate on airway inflammation in asthma
    • 36 Booth H, Richmond I, Ward C, et al. Effect of high dose inhaled fluticasone propionate on airway inflammation in asthma. Am J Respir Crit Care Med 1995;152:45-52.
    • (1995) Am J Respir Crit Care Med , vol.152 , pp. 45-52
    • Booth, H.1    Richmond, I.2    Ward, C.3
  • 37
    • 0030814301 scopus 로고    scopus 로고
    • Bronchial subepithelial fibrosis correlates with airway responsiveness to methacholine
    • 37 Boulet LP, Laviolette M, Turcotte H, et al. Bronchial subepithelial fibrosis correlates with airway responsiveness to methacholine. Chest 1997;112:45-52.
    • (1997) Chest , vol.112 , pp. 45-52
    • Boulet, L.P.1    Laviolette, M.2    Turcotte, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.