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Volumn 35, Issue 4, 2016, Pages 468-478

Elevated CDCP1 predicts poor patient outcome and mediates ovarian clear cell carcinoma by promoting tumor spheroid formation, cell migration and chemoresistance

(24)  He, Y a   Wu, A C a   Harrington, B S a   Davies, C M a,b   Wallace, S J b   Adams, M N a   Palmer, J S a   Roche, D K a   Hollier, B G c   Westbrook, T F d   Hamidi, H e   Konecny, G E e   Winterhoff, B f   Chetty, N P b   Crandon, A J b   Oliveira, N B b   Shannon, C M b   Tinker, A V g   Gilks, C B h   Coward, J I a,b   more..


Author keywords

[No Author keywords available]

Indexed keywords

CARBOPLATIN; CDCP1 PROTEIN, HUMAN; CELL ADHESION MOLECULE; LEUKOCYTE ANTIGEN; PROTEIN KINASE B; TUMOR PROTEIN;

EID: 84955650095     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2015.101     Document Type: Article
Times cited : (43)

References (39)
  • 2
    • 84877042226 scopus 로고    scopus 로고
    • New perspectives on molecular targeted therapy in ovarian clear cell carcinoma
    • Tan DS, Miller RE, Kaye SB. New perspectives on molecular targeted therapy in ovarian clear cell carcinoma. Br J Cancer 2013; 108: 1553-1559.
    • (2013) Br J Cancer , vol.108 , pp. 1553-1559
    • Tan, D.S.1    Miller, R.E.2    Kaye, S.B.3
  • 3
    • 44649186229 scopus 로고    scopus 로고
    • Do clear cell ovarian carcinomas have poorer prognosis compared to other epithelial cell types? A study of 1411 clear cell ovarian cancers
    • Chan JK, Teoh D, Hu JM, Shin JY, Osann K, Kapp DS. Do clear cell ovarian carcinomas have poorer prognosis compared to other epithelial cell types? A study of 1411 clear cell ovarian cancers. Gynecol Oncol 2008; 109: 370-376.
    • (2008) Gynecol Oncol , vol.109 , pp. 370-376
    • Chan, J.K.1    Teoh, D.2    Hu, J.M.3    Shin, J.Y.4    Osann, K.5    Kapp, D.S.6
  • 4
    • 0034213974 scopus 로고    scopus 로고
    • Clinical characteristics of clear cell carcinoma of the ovary: A distinct histologic type with poor prognosis and resistance to platinum-based chemotherapy
    • Sugiyama T, Kamura T, Kigawa J, Terakawa N, Kikuchi Y, Kita T et al. Clinical characteristics of clear cell carcinoma of the ovary: a distinct histologic type with poor prognosis and resistance to platinum-based chemotherapy. Cancer 2000; 88: 2584-2589.
    • (2000) Cancer , vol.88 , pp. 2584-2589
    • Sugiyama, T.1    Kamura, T.2    Kigawa, J.3    Terakawa, N.4    Kikuchi, Y.5    Kita, T.6
  • 5
    • 79957755784 scopus 로고    scopus 로고
    • Exploring palliative treatment outcomes in women with advanced or recurrent ovarian clear cell carcinoma
    • Al-Barrak J, Santos JL, Tinker A, Hoskins P, Gilks CB, Lau H et al. Exploring palliative treatment outcomes in women with advanced or recurrent ovarian clear cell carcinoma. Gynecol Oncol 2011; 122: 107-110.
    • (2011) Gynecol Oncol , vol.122 , pp. 107-110
    • Al-Barrak, J.1    Santos, J.L.2    Tinker, A.3    Hoskins, P.4    Gilks, C.B.5    Lau, H.6
  • 6
    • 84863755765 scopus 로고    scopus 로고
    • Low-stage ovarian clear cell carcinoma: Population-based outcomes in British Columbia, Canada, with evidence for a survival benefit as a result of irradiation
    • Hoskins PJ, Le N, Gilks B, Tinker A, Santos J, WongF et al. Low-stage ovarian clear cell carcinoma: population-based outcomes in British Columbia, Canada, with evidence for a survival benefit as a result of irradiation. JClinOncol2012; 30: 1656-1662.
    • (2012) JClinOncol , vol.30 , pp. 1656-1662
    • Hoskins, P.J.1    Le, N.2    Gilks, B.3    Tinker, A.4    Santos, J.5    Wong, F.6
  • 7
    • 77956495728 scopus 로고    scopus 로고
    • Ovarian cancer development and metastasis
    • Lengyel E. Ovarian cancer development and metastasis. Am J Pathol 2010; 177: 1053-1064.
    • (2010) Am J Pathol , vol.177 , pp. 1053-1064
    • Lengyel, E.1
  • 8
    • 33750312322 scopus 로고    scopus 로고
    • Mechanisms of transcoelomic metastasis in ovarian cancer
    • Tan DS, Agarwal R, Kaye SB. Mechanisms of transcoelomic metastasis in ovarian cancer. Lancet Oncol 2006; 7: 925-934.
    • (2006) Lancet Oncol , vol.7 , pp. 925-934
    • Tan, D.S.1    Agarwal, R.2    Kaye, S.B.3
  • 9
    • 69249220407 scopus 로고    scopus 로고
    • The cell surface glycoprotein CDCP1 in cancer - Insights, opportunities, and challenges
    • Wortmann A, He Y, Deryugina EI, Quigley JP, Hooper JD. The cell surface glycoprotein CDCP1 in cancer - insights, opportunities, and challenges. IUBMB Life 2009; 61: 723-730.
    • (2009) IUBMB Life , vol.61 , pp. 723-730
    • Wortmann, A.1    He, Y.2    Deryugina, E.I.3    Quigley, J.P.4    Hooper, J.D.5
  • 10
    • 84873454160 scopus 로고    scopus 로고
    • Trask loss enhances tumorigenic growth by liberating integrin signaling and growth factor receptor cross-talk in unanchored cells
    • Spassov DS, Wong CH, Wong SY, Reiter JF, Moasser MM. Trask loss enhances tumorigenic growth by liberating integrin signaling and growth factor receptor cross-talk in unanchored cells. Cancer Res 2013; 73: 1168-1179.
    • (2013) Cancer Res , vol.73 , pp. 1168-1179
    • Spassov, D.S.1    Wong, C.H.2    Wong, S.Y.3    Reiter, J.F.4    Moasser, M.M.5
  • 11
    • 77954491295 scopus 로고    scopus 로고
    • A mouse knockout library for secreted and transmembrane proteins
    • Tang T, Li L, Tang J, Li Y, Lin WY, Martin F et al. A mouse knockout library for secreted and transmembrane proteins. Nat Biotechnol 2010; 28: 749-755.
    • (2010) Nat Biotechnol , vol.28 , pp. 749-755
    • Tang, T.1    Li, L.2    Tang, J.3    Li, Y.4    Lin, W.Y.5    Martin, F.6
  • 12
    • 54949158631 scopus 로고    scopus 로고
    • Microarray-based identification of CUB-domain containing protein 1 as a potential prognostic marker in conventional renal cell carcinoma
    • Awakura Y, Nakamura E, Takahashi T, Kotani H, Mikami Y, Kadowaki T et al. Microarray-based identification of CUB-domain containing protein 1 as a potential prognostic marker in conventional renal cell carcinoma. J Cancer Res Clin Oncol 2008; 134: 1363-1369.
    • (2008) J Cancer Res Clin Oncol , vol.134 , pp. 1363-1369
    • Awakura, Y.1    Nakamura, E.2    Takahashi, T.3    Kotani, H.4    Mikami, Y.5    Kadowaki, T.6
  • 13
    • 84874491920 scopus 로고    scopus 로고
    • Identification of CDCP1 as a hypoxia-inducible factor 2α (HIF-2α) target gene that is associated with survival in clear cell renal cell carcinoma patients
    • Emerling BM, Benes CH, Poulogiannis G, Bell EL, Courtney K, Liu H et al. Identification of CDCP1 as a hypoxia-inducible factor 2α (HIF-2α) target gene that is associated with survival in clear cell renal cell carcinoma patients. Proc Natl Acad Sci USA 2013; 110: 3483-3488.
    • (2013) Proc Natl Acad Sci USA , vol.110 , pp. 3483-3488
    • Emerling, B.M.1    Benes, C.H.2    Poulogiannis, G.3    Bell, E.L.4    Courtney, K.5    Liu, H.6
  • 14
    • 84883178190 scopus 로고    scopus 로고
    • Isolation and phenotypic characterization of colorectal cancer stem cells with organ-specific metastatic potential
    • Gao W, Chen L, Ma Z, Du Z, Zhao Z, Hu Z et al. Isolation and phenotypic characterization of colorectal cancer stem cells with organ-specific metastatic potential. Gastroenterology 2013; 145: 636-46. e5.
    • (2013) Gastroenterology , vol.145
    • Gao, W.1    Chen, L.2    Ma, Z.3    Du, Z.4    Zhao, Z.5    Hu, Z.6
  • 15
    • 62849106338 scopus 로고    scopus 로고
    • Expression of CUB domain containing protein (CDCP1) is correlated with prognosis and survival of patients with adenocarcinoma of lung
    • Ikeda J, Oda T, Inoue M, Uekita T, Sakai R, Okumura M et al. Expression of CUB domain containing protein (CDCP1) is correlated with prognosis and survival of patients with adenocarcinoma of lung. Cancer Sci 2009; 100: 429-433.
    • (2009) Cancer Sci , vol.100 , pp. 429-433
    • Ikeda, J.1    Oda, T.2    Inoue, M.3    Uekita, T.4    Sakai, R.5    Okumura, M.6
  • 16
    • 77953797255 scopus 로고    scopus 로고
    • CUB domain-containing protein 1, a prognostic factor for human pancreatic cancers, promotes cell migration and extracellular matrix degradation
    • Miyazawa Y, Uekita T, Hiraoka N, Fujii S, Kosuge T, Kanai Y et al. CUB domain-containing protein 1, a prognostic factor for human pancreatic cancers, promotes cell migration and extracellular matrix degradation. Cancer Res 2010; 70: 5136-5146.
    • (2010) Cancer Res , vol.70 , pp. 5136-5146
    • Miyazawa, Y.1    Uekita, T.2    Hiraoka, N.3    Fujii, S.4    Kosuge, T.5    Kanai, Y.6
  • 17
    • 79952165882 scopus 로고    scopus 로고
    • VHL loss in renal cell carcinoma leads to up-regulation of CUB domain-containing protein 1 to stimulate PKCδ-driven migration
    • Razorenova OV, Finger EC, Colavitti R, Chernikova SB, Boiko AD, Chan CK et al. VHL loss in renal cell carcinoma leads to up-regulation of CUB domain-containing protein 1 to stimulate PKCδ-driven migration. Proc Natl Acad Sci USA 2011; 108: 1931-1936.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 1931-1936
    • Razorenova, O.V.1    Finger, E.C.2    Colavitti, R.3    Chernikova, S.B.4    Boiko, A.D.5    Chan, C.K.6
  • 18
    • 84865637021 scopus 로고    scopus 로고
    • Blocking of CDCP1 cleavage in vivo prevents Akt-dependent survival and inhibits metastatic colonization through PARP1-mediated apoptosis of cancer cells
    • Casar B, He Y, Iconomou M, Hooper JD, Quigley JP, Deryugina EI. Blocking of CDCP1 cleavage in vivo prevents Akt-dependent survival and inhibits metastatic colonization through PARP1-mediated apoptosis of cancer cells. Oncogene 2012; 31: 3924-3938.
    • (2012) Oncogene , vol.31 , pp. 3924-3938
    • Casar, B.1    He, Y.2    Iconomou, M.3    Hooper, J.D.4    Quigley, J.P.5    Deryugina, E.I.6
  • 20
    • 84891949141 scopus 로고    scopus 로고
    • In vivo cleaved CDCP1 promotes early tumor dissemination via complexing with activated beta1 integrin and induction of FAK/PI3K/Akt motility signaling
    • Casar B, Rimann I, Kato H, Shattil SJ, Quigley JP, Deryugina EI. In vivo cleaved CDCP1 promotes early tumor dissemination via complexing with activated beta1 integrin and induction of FAK/PI3K/Akt motility signaling. Oncogene 2014; 33: 255-268.
    • (2014) Oncogene , vol.33 , pp. 255-268
    • Casar, B.1    Rimann, I.2    Kato, H.3    Shattil, S.J.4    Quigley, J.P.5    Deryugina, E.I.6
  • 22
    • 84870176548 scopus 로고    scopus 로고
    • Targeting pathways contributing to epithelial-mesenchymal transition (EMT) in epithelial ovarian cancer
    • Huang RY, Chung VY, Thiery JP. Targeting pathways contributing to epithelial-mesenchymal transition (EMT) in epithelial ovarian cancer. Curr Drug Targets 2012; 13: 1649-1653.
    • (2012) Curr Drug Targets , vol.13 , pp. 1649-1653
    • Huang, R.Y.1    Chung, V.Y.2    Thiery, J.P.3
  • 23
    • 84858986330 scopus 로고    scopus 로고
    • The cell surface glycoprotein CUB domain-containing protein 1 (CDCP1) contributes to epidermal growth factor receptor-mediated cell migration
    • Dong Y, He Y, de Boer L, Stack MS, Lumley JW, Clements JA et al. The cell surface glycoprotein CUB domain-containing protein 1 (CDCP1) contributes to epidermal growth factor receptor-mediated cell migration. J Biol Chem 2012; 287: 9792-9803.
    • (2012) J Biol Chem , vol.287 , pp. 9792-9803
    • Dong, Y.1    He, Y.2    De Boer, L.3    Stack, M.S.4    Lumley, J.W.5    Clements, J.A.6
  • 24
    • 0037468568 scopus 로고    scopus 로고
    • Subtractive immunization using highly metastatic human tumor cells identifies SIMA135/CDCP1, a 135 kDa cell surface phosphorylated glycoprotein antigen
    • Hooper JD, Zijlstra A, Aimes RT, Liang H, Claassen GF, Tarin D et al. Subtractive immunization using highly metastatic human tumor cells identifies SIMA135/CDCP1, a 135 kDa cell surface phosphorylated glycoprotein antigen. Oncogene 2003; 22: 1783-1794.
    • (2003) Oncogene , vol.22 , pp. 1783-1794
    • Hooper, J.D.1    Zijlstra, A.2    Aimes, R.T.3    Liang, H.4    Claassen, G.F.5    Tarin, D.6
  • 25
    • 35649025769 scopus 로고    scopus 로고
    • CUB domain-containing protein 1 is a novel regulator of anoikis resistance in lung adenocarcinoma
    • Uekita T, Jia L, Narisawa-Saito M, Yokota J, Kiyono T, Sakai R. CUB domain-containing protein 1 is a novel regulator of anoikis resistance in lung adenocarcinoma. Mol Cell Biol 2007; 27: 7649-7660.
    • (2007) Mol Cell Biol , vol.27 , pp. 7649-7660
    • Uekita, T.1    Jia, L.2    Narisawa-Saito, M.3    Yokota, J.4    Kiyono, T.5    Sakai, R.6
  • 26
    • 84873179365 scopus 로고    scopus 로고
    • Update on first-line treatment of advanced ovarian carcinoma
    • Kemp Z, Ledermann J. Update on first-line treatment of advanced ovarian carcinoma. Int J Womens Health 2013; 5: 45-51.
    • (2013) Int J Womens Health , vol.5 , pp. 45-51
    • Kemp, Z.1    Ledermann, J.2
  • 27
    • 0036327586 scopus 로고    scopus 로고
    • Sensitivity to anticancer agents and resistance mechanisms in clear cell carcinoma of the ovary
    • Itamochi H, Kigawa J, Sultana H, Iba T, Akeshima R, Kamazawa S et al. Sensitivity to anticancer agents and resistance mechanisms in clear cell carcinoma of the ovary. Jpn J Cancer Res 2002; 93: 723-728.
    • (2002) Jpn J Cancer Res , vol.93 , pp. 723-728
    • Itamochi, H.1    Kigawa, J.2    Sultana, H.3    Iba, T.4    Akeshima, R.5    Kamazawa, S.6
  • 28
    • 59249106025 scopus 로고    scopus 로고
    • Glutathione peroxidase 3 is a candidate mechanism of anticancer drug resistance of ovarian clear cell adenocarcinoma
    • Saga Y, Ohwada M, Suzuki M, Konno R, Kigawa J, Ueno S et al. Glutathione peroxidase 3 is a candidate mechanism of anticancer drug resistance of ovarian clear cell adenocarcinoma. Oncol Rep 2008; 20: 1299-1303.
    • (2008) Oncol Rep , vol.20 , pp. 1299-1303
    • Saga, Y.1    Ohwada, M.2    Suzuki, M.3    Konno, R.4    Kigawa, J.5    Ueno, S.6
  • 29
    • 20444448808 scopus 로고    scopus 로고
    • An evaluation of cytotoxicity of the taxane and platinum agents combination treatment in a panel of human ovarian carcinoma cell lines
    • Smith JA, Ngo H, Martin MC, Wolf JK. An evaluation of cytotoxicity of the taxane and platinum agents combination treatment in a panel of human ovarian carcinoma cell lines. Gynecol Oncol 2005; 98: 141-145.
    • (2005) Gynecol Oncol , vol.98 , pp. 141-145
    • Smith, J.A.1    Ngo, H.2    Martin, M.C.3    Wolf, J.K.4
  • 30
    • 82755195699 scopus 로고    scopus 로고
    • Cellular settings mediating Src substrate switching between focal adhesion kinase tyrosine 861 and CUB-domain-containing protein 1 (CDCP1) tyrosine 734
    • Wortmann A, He Y, Christensen ME, Linn M, Lumley JW, Pollock PM et al. Cellular settings mediating Src substrate switching between focal adhesion kinase tyrosine 861 and CUB-domain-containing protein 1 (CDCP1) tyrosine 734. J Biol Chem 2011; 286: 42303-42315.
    • (2011) J Biol Chem , vol.286 , pp. 42303-42315
    • Wortmann, A.1    He, Y.2    Christensen, M.E.3    Linn, M.4    Lumley, J.W.5    Pollock, P.M.6
  • 31
    • 65249184413 scopus 로고    scopus 로고
    • Phosphorylation of the SRC epithelial substrate Trask is tightly regulated in normal epithelia but widespread in many human epithelial cancers
    • Wong CH, Baehner FL, Spassov DS, Ahuja D, Wang D, Hann B et al. Phosphorylation of the SRC epithelial substrate Trask is tightly regulated in normal epithelia but widespread in many human epithelial cancers. Clin Cancer Res 2009; 15: 2311-2322.
    • (2009) Clin Cancer Res , vol.15 , pp. 2311-2322
    • Wong, C.H.1    Baehner, F.L.2    Spassov, D.S.3    Ahuja, D.4    Wang, D.5    Hann, B.6
  • 32
    • 40849119661 scopus 로고    scopus 로고
    • The role of membrane microdomains in transmembrane signaling through the epithelial glycoprotein Gp140/CDCP1
    • Alvares SM, Dunn CA, Brown TA, Wayner EE, Carter WG. The role of membrane microdomains in transmembrane signaling through the epithelial glycoprotein Gp140/CDCP1. Biochim Biophys Acta 2008; 1780: 486-496.
    • (2008) Biochim Biophys Acta , vol.1780 , pp. 486-496
    • Alvares, S.M.1    Dunn, C.A.2    Brown, T.A.3    Wayner, E.E.4    Carter, W.G.5
  • 33
    • 84882241564 scopus 로고    scopus 로고
    • Stratum basale keratinocyte expression of the cell-surface glycoprotein CDCP1 during epidermogenesis and its role in keratinocyte migration
    • McGovern JA, Heinemann JR, Burke LJ, Dawson R, Parker TJ, Upton Z et al. Stratum basale keratinocyte expression of the cell-surface glycoprotein CDCP1 during epidermogenesis and its role in keratinocyte migration. Br J Dermatol 2013; 168: 496-503.
    • (2013) Br J Dermatol , vol.168 , pp. 496-503
    • McGovern, J.A.1    Heinemann, J.R.2    Burke, L.J.3    Dawson, R.4    Parker, T.J.5    Upton, Z.6
  • 34
    • 45549086918 scopus 로고    scopus 로고
    • Targeting CUB domain-containing protein 1 with a monoclonal antibody inhibits metastasis in a prostate cancer model
    • Siva AC, Wild MA, Kirkland RE, Nolan MJ, Lin B, Maruyama T et al. Targeting CUB domain-containing protein 1 with a monoclonal antibody inhibits metastasis in a prostate cancer model. Cancer Res 2008; 68: 3759-3766.
    • (2008) Cancer Res , vol.68 , pp. 3759-3766
    • Siva, A.C.1    Wild, M.A.2    Kirkland, R.E.3    Nolan, M.J.4    Lin, B.5    Maruyama, T.6
  • 36
    • 84896689206 scopus 로고    scopus 로고
    • EGF inhibits constitutive internalization and palmitoylation-dependent degradation of membrane-spanning procancer CDCP1 promoting its availability on the cell surface
    • Adams MN, Harrington BS, He Y, Davies CM, Wallace SJ, Chetty NP et al. EGF inhibits constitutive internalization and palmitoylation-dependent degradation of membrane-spanning procancer CDCP1 promoting its availability on the cell surface. Oncogene 2014; 34: 1375-1383.
    • (2014) Oncogene , vol.34 , pp. 1375-1383
    • Adams, M.N.1    Harrington, B.S.2    He, Y.3    Davies, C.M.4    Wallace, S.J.5    Chetty, N.P.6
  • 37
    • 0035184068 scopus 로고    scopus 로고
    • Beta 1-integrins regulate the formation and adhesion of ovarian carcinoma multicellular spheroids
    • Casey RC, Burleson KM, Skubitz KM, Pambuccian SE, Oegema TR Jr, Ruff LE et al. Beta 1-integrins regulate the formation and adhesion of ovarian carcinoma multicellular spheroids. Am J Pathol 2001; 159: 2071-2080.
    • (2001) Am J Pathol , vol.159 , pp. 2071-2080
    • Casey, R.C.1    Burleson, K.M.2    Skubitz, K.M.3    Pambuccian, S.E.4    Oegema, T.R.5    Ruff, L.E.6
  • 38
    • 38949109297 scopus 로고    scopus 로고
    • Suppression of anoikis by the neurotrophic receptor TrkB in human ovarian cancer
    • Yu X, Liu L, Cai B, He Y, Wan X. Suppression of anoikis by the neurotrophic receptor TrkB in human ovarian cancer. Cancer Sci 2008; 99: 543-552.
    • (2008) Cancer Sci , vol.99 , pp. 543-552
    • Yu, X.1    Liu, L.2    Cai, B.3    He, Y.4    Wan, X.5
  • 39
    • 84890856047 scopus 로고    scopus 로고
    • Cell cycle arrest or survival signaling through alphav integrins, activation of PKC and ERK1/2 lead to anoikis resistance of ovarian cancer spheroids
    • Carduner L, Picot CR, Leroy-Dudal J, Blay L, Kellouche S, Carreiras F. Cell cycle arrest or survival signaling through alphav integrins, activation of PKC and ERK1/2 lead to anoikis resistance of ovarian cancer spheroids. Exp Cell Res 2014; 320: 329-342.
    • (2014) Exp Cell Res , vol.320 , pp. 329-342
    • Carduner, L.1    Picot, C.R.2    Leroy-Dudal, J.3    Blay, L.4    Kellouche, S.5    Carreiras, F.6


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