Functional role of cell surface CUB domain-containing protein 1 in tumor cell dissemination

Molecular Cancer Research

Volumn 7, Issue 8, 2009, Pages 1197-1211

  Deryugina, Elena I ^a   Conn, Erin M ^a   Wortmann, Andreas ^b   Partridge, Juneth J ^a   Kupriyanova, Tatyana A ^a   Ardi, Veronica C ^a   Hooper, John D ^b   Quigley, James P ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b QUEENSLAND UNIVERSITY OF TECHNOLOGY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

BENZYLOXYCARBONYLVALYLALANYLASPARTYL FLUOROMETHYL KETONE; CUB DOMAIN CONTAINING PROTEIN 1; DOXORUBICIN; HIGH DISSEMINATING VARIANT OF PROSTATE CARCINOMA 3; MEMBRANE PROTEIN; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY 41 2; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CANCER CELL; CANCER INVASION; CANCER STAGING; CELL SURFACE; CELL SURVIVAL; CHICK; CONTROLLED STUDY; DOSE RESPONSE; DRUG MECHANISM; EMBRYO; EXPERIMENTAL MODEL; HELA CELL; HUMAN; HUMAN CELL; IMMUNE DEFICIENCY; IMMUNIZATION; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; METASTASIS; MOUSE; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; QUANTITATIVE ANALYSIS;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, CD; APOPTOSIS; CELL ADHESION MOLECULES; CELL MEMBRANE; CELL SHAPE; CHICK EMBRYO; DISEASE MODELS, ANIMAL; DOXORUBICIN; HELA CELLS; HUMANS; KINETICS; MALE; MICE; NEOPLASM METASTASIS; NEOPLASM PROTEINS; NEOPLASMS; PHOSPHOTYROSINE; PROSTATIC NEOPLASMS; TUMOR STEM CELL ASSAY;

MUS;

EID: 69449097220     PISSN: 15417786     EISSN: None     Source Type: Journal    
DOI: 10.1158/1541-7786.MCR-09-0100     Document Type: Article

References (31)

1. Scherl-Mostageer M, Sommergruber W, Abseher R, Hauptmann R, Ambros P, Schweifer N. Identification of a novel gene, CDCP1, overexpressed in human colorectal cancer. Oncogene 2001;20:4402-4408 (Pubitemid 32726882)
2. Hooper JD, Zijlstra A, Aimes RT, et al. Subtractive immunization using highly metastatic human tumor cells identifies SIMA135/CDCP1, a 135 kDa cell surface phosphorylated glycoprotein antigen. Oncogene 2003;22:1783-1794 (Pubitemid 36513138)
3. Bhatt AS, Erdjument-Bromage H, Tempst P, Craik CS, Moasser MM. Adhesion signaling by a novel mitotic substrate of src kinases. Oncogene 2005;24:5333-5343 (Pubitemid 43080103)
4. Alvares SM, Dunn CA, Brown TA, Wayner EE, Carter WG. The role of membrane microdomains in transmembrane signaling through the epithelial glycoprotein Gp140/CDCP1. Biochim Biophys Acta 2008;1780:486-496
5. Benes CH, Wu N, Elia AE, Dharia T, Cantley LC, Soltoff SP. The C2 domain of PKCδ is a phosphotyrosine binding domain. Cell 2005;121:271-280
6. Uekita T, Jia L, Narisawa-Saito M, Yokota J, Kiyono T, Sakai R. CUB domain-containing protein 1 is a novel regulator of anoikis resistance in lung adenocarcinoma. Mol Cell Biol 2007;27:7649-7660 (Pubitemid 350033670)
7. Uekita T, Tanaka M, Takigahira M, et al. CUB-domain-containing protein 1 regulates peritoneal dissemination of gastric scirrhous carcinoma. Am J Pathol 2008;172:1729-1739 (Pubitemid 351793363)
8. Conze T, Lammers R, Kuci S, et al. CDCP1 is a novel marker for hematopoietic stem cells. Ann N Y Acad Sci 2003;996:222-226 (Pubitemid 36706603)
9. Buhring HJ, Kuci S, Conze T, et al. CDCP1 identifies a broad spectrum of normal and malignant stem/progenitor cell subsets of hematopoietic and nonhematopoietic origin. Stem Cells 2004;22:334-343 (Pubitemid 38736617)
10. Awakura Y, Nakamura E, Takahashi T, et al. Microarray-based identification of CUB-domain containing protein 1 as a potential prognostic marker in conventional renal cell carcinoma. J Cancer Res Clin Oncol 2008;134:1363-1369
11. Ikeda JI, Oda T, Inoue M, et al. Expression of CUB domain containing protein (CDCP1) is correlated with prognosis and survival of patients with adenocarcinoma of lung. Cancer Sci 2008.
12. Siva AC, Wild MA, Kirkland RE, et al. Targeting CUB domain-containing protein 1 with a monoclonal antibody inhibits metastasis in a prostate cancer model. Cancer Res 2008;68:3759-3766
13. Taylor RC, Cullen SP, Martin SJ. Apoptosis: controlled demolition at the cellular level. Nat Rev Mol Cell Biol 2008;9:231-241
14. Zhang J, Reedy MC, Hannun YA, Obeid LM. Inhibition of caspases inhibits the release of apoptotic bodies: Bcl-2 inhibits the initiation of formation of apoptotic bodies in chemotherapeutic agent-induced apoptosis. J Cell Biol 1999;145:99-108. (Pubitemid 29177678)
15. Gamen S, Anel A, Perez-Galan P, et al. Doxorubicin treatment activates a Z-VAD-sensitive caspase, which causes Δψm loss, caspase-9 activity, and apoptosis in Jurkat cells. Exp Cell Res 2000;258:223-235 (Pubitemid 30461124)
16. 2-terminal kinase to induce apoptosis. Mol Biol Cell 2005;16:3821-3831
17. Casares N, Pequignot MO, Tesniere A, et al. Caspase-dependent immunogenicity of doxorubicin-induced tumor cell death. J Exp Med 2005;202:1691-1701 (Pubitemid 41815875)
18. Huigsloot M, Tijdens IB, Mulder GJ, van de Water B. Differential regulation of doxorubicin-induced mitochondrial dysfunction and apoptosis by Bcl-2 in mammary adenocarcinoma (MTLn3) cells. J Biol Chem 2002;277:35869-35879
19. Perry SE, Robinson P, Melcher A, et al. Expression of the CUB domain containing protein 1 (CDCP1) gene in colorectal tumour cells. FEBS Lett 2007;581:1137-1142 (Pubitemid 46385936)
20. Brown TA, Yang TM, Zaitsevskaia T, et al. Adhesion or plasmin regulates tyrosine phosphorylation of a novel membrane glycoprotein p80/gp140/CUB domain-containing protein 1 in epithelia. J Biol Chem 2004;279:14772-14783 (Pubitemid 38618866)
21. Brooks PC, Lin JM, French DL, Quigley JP. Subtractive immunization yields monoclonal antibodies that specifically inhibit metastasis. J Cell Biol 1993;122:1351-1359 (Pubitemid 23277303)
22. Zijlstra A, Testa JE, Quigley JP. Targeting the proteome/epitome, implementation of subtractive immunization. Biochem Biophys Res Commun 2003;303:733-744 (Pubitemid 36384917)
23. Zijlstra A, Lewis J, Degryse B, Stuhlmann H, Quigley JP. The inhibition of tumor cell intravasation and subsequent metastasis via regulation of in vivo tumor cell motility by the tetraspanin CD151. Cancer Cell 2008;13:221-234 (Pubitemid 351318371)
24. Goldstein NI, Fisher PB. Surface-epitope masking (SEM): an immunological subtraction approach for developing monoclonal antibodies targeting surface-expressed molecules. Methods Mol Biol 2007;383:245-258
25. Huerta S, Goulet EJ, Huerta-Yepez S, Livingston EH. Screening and detection of apoptosis. J Surg Res 2007;139:143-156
26. Tsai YC, Mendoza A, Mariano JM, et al. The ubiquitin ligase gp78 promotes sarcoma metastasis by targeting KAI1 for degradation. Nat Med 2007;13:1504-1509 (Pubitemid 350224250)
27. Kouros-Mehr H, Bechis SK, Slorach EM, et al. GATA-3 links tumor differentiation and dissemination in a luminal breast cancer model. Cancer Cell 2008;13:141-152 (Pubitemid 351163164)
28. Sanz L, Kristensen P, Blanco B, et al. Single-chain antibody-based gene therapy: inhibition of tumor growth by in situ production of phage-derived human antibody fragments blocking functionally active sites of cell-associated matrices. Gene Ther 2002;9:1049-1053 (Pubitemid 34893591)
29. Tezel G, Wax MB. The mechanisms of hsp27 antibody-mediated apoptosis in retinal neuronal cells. J Neurosci 2000;20:3552-3562 (Pubitemid 30266217)
30. Durrant LG, Harding SJ, Green NH, Buckberry LD, Parsons T. A new anticancer glycolipid monoclonal antibody, SC104, which directly induces tumor cell apoptosis. Cancer Res 2006;66:5901-5909 (Pubitemid 43927145)
31. Deryugina EI, Zijlstra A, Partridge JJ, et al. Unexpected effect of matrix metalloproteinase down-regulation on vascular intravasation and metastasis of human fibrosarcoma cells selected in vivo for high rates of dissemination. Cancer Res 2005;65:10959-10969 (Pubitemid 41713365)