Structural Insights into KCTD Protein Assembly and Cullin3 Recognition

Journal of Molecular Biology

Volumn 428, Issue 1, 2016, Pages 92-107

  Ji, Alan X ^a   Chu, Anh ^a   Nielsen, Tine Kragh ^b   Benlekbir, Samir ^c   Rubinstein, John L ^a,c   Privé, Gilbert G ^a,b  

^a UNIVERSITY OF TORONTO   (Canada)

^b PRINCESS MARGARET HOSPITAL   (Canada)

^c HOSPITAL FOR SICK CHILDREN RESEARCH INSTITUTE   (Canada)

Author keywords

Abbreviations cryo EM cryo electron microscopy; Cul3 Cullin3; ITC isothermal titration calorimetry; PEG polyethylene glycol; SEC size exclusion chromatography

Indexed keywords

CULLIN 3; ELONGIN C; KCTD PROTEIN; KCTD1 PROTEIN; KCTD16 PROTEIN; KCTD17 PROTEIN; KCTD5 PROTEIN; KCTD6 PROTEIN; KCTD9 PROTEIN; PROTEIN; SKP1 PROTEIN; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; VOLTAGE GATED POTASSIUM CHANNEL; CUL3 PROTEIN, HUMAN; CULLIN; KCTD1 PROTEIN, HUMAN; KCTD9 PROTEIN, HUMAN; MACROMOLECULE; POTASSIUM CHANNEL; PROTEIN BINDING; REPRESSOR PROTEIN;

ARTICLE; BINDING AFFINITY; BINDING SITE; CARBOXY TERMINAL SEQUENCE; COMPLEX FORMATION; CRYSTAL STRUCTURE; HUMAN; ISOTHERMAL TITRATION CALORIMETRY; MOLECULAR DYNAMICS; MOLECULAR RECOGNITION; PLASTICITY; POINT MUTATION; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN CROSS LINKING; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; SIZE EXCLUSION CHROMATOGRAPHY; STOICHIOMETRY; SURFACE AREA; CHEMICAL STRUCTURE; CHEMISTRY; CRYOELECTRON MICROSCOPY; MACROMOLECULE; METABOLISM; PROTEIN MULTIMERIZATION; X RAY CRYSTALLOGRAPHY;

CRYOELECTRON MICROSCOPY; CRYSTALLOGRAPHY, X-RAY; CULLIN PROTEINS; MACROMOLECULAR SUBSTANCES; MODELS, MOLECULAR; POTASSIUM CHANNELS; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN MULTIMERIZATION; REPRESSOR PROTEINS;

EID: 84955617774     PISSN: 00222836     EISSN: 10898638     Source Type: Journal    
DOI: 10.1016/j.jmb.2015.08.019     Document Type: Article

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