메뉴 건너뛰기




Volumn 36, Issue 4, 2016, Pages 647-654

Evidence That Cingulin Regulates Endothelial Barrier Function in Vitro and in Vivo

Author keywords

capillary permeability; human umbilical vein endothelial cells; junctional adhesion molecules; mouse, mutant strain; vascular diseases

Indexed keywords

CINGULIN; GUANINE NUCLEOTIDE EXCHANGE FACTOR H1; MESSENGER RNA; PROTEIN ZO1; TIGHT JUNCTION PROTEIN; UNCLASSIFIED DRUG; VASCULAR ENDOTHELIAL CADHERIN; ACTIN BINDING PROTEIN; ARHGEF2 PROTEIN, HUMAN; CGN PROTEIN, HUMAN; CGN PROTEIN, MOUSE; CLAUDIN 5; CLDN5 PROTEIN, HUMAN; MEMBRANE PROTEIN; RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR; TJP1 PROTEIN, HUMAN;

EID: 84955605901     PISSN: 10795642     EISSN: 15244636     Source Type: Journal    
DOI: 10.1161/ATVBAHA.115.307032     Document Type: Article
Times cited : (47)

References (40)
  • 1
    • 77952756845 scopus 로고    scopus 로고
    • Molecular basis of the core structure of tight junctions
    • Furuse M. Molecular basis of the core structure of tight junctions. Cold Spring Harb Perspect Biol. 2010;2:a002907. doi: 10.1101/cshperspect. a002907.
    • (2010) Cold Spring Harb Perspect Biol , vol.2
    • Furuse, M.1
  • 2
    • 39849103311 scopus 로고    scopus 로고
    • The cytoplasmic plaque of tight junctions: A scaffolding and signalling center
    • Guillemot L, Paschoud S, Pulimeno P, Foglia A, Citi S. The cytoplasmic plaque of tight junctions: a scaffolding and signalling center. Biochim Biophys Acta. 2008;1778:601-613. doi: 10.1016/j.bbamem.2007.09.032.
    • (2008) Biochim Biophys Acta , vol.1778 , pp. 601-613
    • Guillemot, L.1    Paschoud, S.2    Pulimeno, P.3    Foglia, A.4    Citi, S.5
  • 3
    • 80155172045 scopus 로고    scopus 로고
    • Regulation of small GTPases at epithelial cell-cell junctions
    • Citi S, Spadaro D, Schneider Y, Stutz J, Pulimeno P. Regulation of small GTPases at epithelial cell-cell junctions. Mol Membr Biol. 2011;28:427-444. doi: 10.3109/09687688.2011.603101.
    • (2011) Mol Membr Biol , vol.28 , pp. 427-444
    • Citi, S.1    Spadaro, D.2    Schneider, Y.3    Stutz, J.4    Pulimeno, P.5
  • 4
    • 84904255172 scopus 로고    scopus 로고
    • SnapShot: Epithelial tight junctions
    • Matter K, Balda MS. SnapShot: epithelial tight junctions. Cell. 2014;157:992-992.e1. doi: 10.1016/j.cell.2014.04.027.
    • (2014) Cell , vol.157 , pp. 992-992e1
    • Matter, K.1    Balda, M.S.2
  • 5
    • 76349098227 scopus 로고    scopus 로고
    • Rho signaling and tight junction functions
    • Terry S, Nie M, Matter K, Balda MS. Rho signaling and tight junction functions. Physiology (Bethesda). 2010;25:16-26. doi: 10.1152/ physiol.00034.2009.
    • (2010) Physiology (Bethesda) , vol.25 , pp. 16-26
    • Terry, S.1    Nie, M.2    Matter, K.3    Balda, M.S.4
  • 6
    • 84859854623 scopus 로고    scopus 로고
    • Vascular endothelial-cadherin and vascular stability
    • Dejana E, Giampietro C. Vascular endothelial-cadherin and vascular stability. Curr Opin Hematol. 2012;19:218-223. doi: 10.1097/ MOH.0b013e3283523e1c.
    • (2012) Curr Opin Hematol , vol.19 , pp. 218-223
    • Dejana, E.1    Giampietro, C.2
  • 8
    • 84943255434 scopus 로고    scopus 로고
    • Brain barriers: Crosstalk between complex tight junctions and adherens junctions
    • Tietz S, Engelhardt B. Brain barriers: Crosstalk between complex tight junctions and adherens junctions. J Cell Biol. 2015;209:493-506. doi: 10.1083/jcb.201412147.
    • (2015) J Cell Biol , vol.209 , pp. 493-506
    • Tietz, S.1    Engelhardt, B.2
  • 9
    • 38549128935 scopus 로고    scopus 로고
    • VE-cadherin: The major endothelial adhesion molecule controlling cellular junctions and blood vessel formation
    • Vestweber D. VE-cadherin: the major endothelial adhesion molecule controlling cellular junctions and blood vessel formation. Arterioscler Thromb Vasc Biol. 2008;28:223-232. doi: 10.1161/ATVBAHA.107.158014.
    • (2008) Arterioscler Thromb Vasc Biol , vol.28 , pp. 223-232
    • Vestweber, D.1
  • 10
  • 11
    • 84874387050 scopus 로고    scopus 로고
    • Claudin-5 controls intercellular barriers of human dermal microvascular but not human umbilical vein endothelial cells
    • Kluger MS, Clark PR, Tellides G, Gerke V, Pober JS. Claudin-5 controls intercellular barriers of human dermal microvascular but not human umbilical vein endothelial cells. Arterioscler Thromb Vasc Biol. 2013;33:489-500. doi: 10.1161/ATVBAHA.112.300893.
    • (2013) Arterioscler Thromb Vasc Biol , vol.33 , pp. 489-500
    • Kluger, M.S.1    Clark, P.R.2    Tellides, G.3    Gerke, V.4    Pober, J.S.5
  • 12
    • 0024291701 scopus 로고
    • Cingulin, a new peripheral component of tight junctions
    • Citi S, Sabanay H, Jakes R, Geiger B, Kendrick-Jones J. Cingulin, a new peripheral component of tight junctions. Nature. 1988;333:272-276. doi: 10.1038/333272a0.
    • (1988) Nature , vol.333 , pp. 272-276
    • Citi, S.1    Sabanay, H.2    Jakes, R.3    Geiger, B.4    Kendrick-Jones, J.5
  • 13
    • 17844402719 scopus 로고    scopus 로고
    • Binding of gef-h1 to the tight junction-associated adaptor cingulin results in inhibition of rho signaling and g1/s phase transition
    • Aijaz S, D'Atri F, Citi S, Balda MS, Matter K. Binding of gef-h1 to the tight junction-associated adaptor cingulin results in inhibition of rho signaling and g1/s phase transition. Dev Cell. 2005;8:777-786
    • (2005) Dev Cell , vol.8 , pp. 777-786
    • Aijaz, S.1    D'Atri, F.2    Citi, S.3    Balda, M.S.4    Matter, K.5
  • 14
    • 33746637520 scopus 로고    scopus 로고
    • Cingulin regulates claudin-2 expression and cell proliferation through the small gtpase rhoa
    • Guillemot L, Citi S. Cingulin regulates claudin-2 expression and cell proliferation through the small gtpase rhoa. Mol Biol Cell. 2006;17:3569-3577
    • (2006) Mol Biol Cell , vol.17 , pp. 3569-3577
    • Guillemot, L.1    Citi, S.2
  • 15
    • 79551612886 scopus 로고    scopus 로고
    • Spatially restricted activation of RhoA signalling at epithelial junctions by p114RhoGEF drives junction formation and morphogenesis
    • Terry SJ, Zihni C, Elbediwy A, Vitiello E, Leefa Chong San IV, Balda MS, Matter K. Spatially restricted activation of RhoA signalling at epithelial junctions by p114RhoGEF drives junction formation and morphogenesis. Nat Cell Biol. 2011;13:159-166. doi: 10.1038/ncb2156.
    • (2011) Nat Cell Biol , vol.13 , pp. 159-166
    • Terry, S.J.1    Zihni, C.2    Elbediwy, A.3    Vitiello, E.4    Leefa Chong San, I.V.5    Balda, M.S.6    Matter, K.7
  • 16
    • 84903520122 scopus 로고    scopus 로고
    • MgcRacGAP interacts with cingulin and paracingulin to regulate Rac1 activation and development of the tight junction barrier during epithelial junction assembly
    • Guillemot L, Guerrera D, Spadaro D, Tapia R, Jond L, Citi S. MgcRacGAP interacts with cingulin and paracingulin to regulate Rac1 activation and development of the tight junction barrier during epithelial junction assembly. Mol Biol Cell. 2014;25:1995-2005. doi: 10.1091/mbc.E13-11-0680.
    • (2014) Mol Biol Cell , vol.25 , pp. 1995-2005
    • Guillemot, L.1    Guerrera, D.2    Spadaro, D.3    Tapia, R.4    Jond, L.5    Citi, S.6
  • 17
    • 84872227438 scopus 로고    scopus 로고
    • Cingulin is dispensable for epithelial barrier function and tight junction structure, and plays a role in the control of claudin-2 expression and response to duodenal mucosa injury
    • Guillemot L, Schneider Y, Brun P, Castagliuolo I, Pizzuti D, Martines D, Jond L, Bongiovanni M, Citi S. Cingulin is dispensable for epithelial barrier function and tight junction structure, and plays a role in the control of claudin-2 expression and response to duodenal mucosa injury. J Cell Sci. 2012;125(pt 21):5005-5014. doi: 10.1242/jcs.101261.
    • (2012) J Cell Sci , vol.125 , pp. 5005-5014
    • Guillemot, L.1    Schneider, Y.2    Brun, P.3    Castagliuolo, I.4    Pizzuti, D.5    Martines, D.6    Jond, L.7    Bongiovanni, M.8    Citi, S.9
  • 19
    • 0025858852 scopus 로고
    • Cingulin, a specific protein component of tight junctions, is expressed in normal and neoplastic human epithelial tissues
    • Citi S, Amorosi A, Franconi F, Giotti A, Zampi G. Cingulin, a specific protein component of tight junctions, is expressed in normal and neoplastic human epithelial tissues. Am J Pathol. 1991;138:781-789.
    • (1991) Am J Pathol , vol.138 , pp. 781-789
    • Citi, S.1    Amorosi, A.2    Franconi, F.3    Giotti, A.4    Zampi, G.5
  • 21
    • 77952761852 scopus 로고    scopus 로고
    • Mechanotransduction by GEF-H1 as a novel mechanism of ventilatorinduced vascular endothelial permeability
    • Birukova AA, Fu P, Xing J, Yakubov B, Cokic I, Birukov KG. Mechanotransduction by GEF-H1 as a novel mechanism of ventilatorinduced vascular endothelial permeability. Am J Physiol Lung Cell Mol Physiol. 2010;298:L837-L848. doi: 10.1152/ajplung.00263.2009.
    • (2010) Am J Physiol Lung Cell Mol Physiol , vol.298 , pp. L837-L848
    • Birukova, A.A.1    Fu, P.2    Xing, J.3    Yakubov, B.4    Cokic, I.5    Birukov, K.G.6
  • 24
  • 25
    • 0037008741 scopus 로고    scopus 로고
    • Evidence for a functional interaction between cingulin and ZO-1 in cultured cells
    • D'Atri F, Nadalutti F, Citi S. Evidence for a functional interaction between cingulin and ZO-1 in cultured cells. J Biol Chem. 2002;277:27757-27764. doi: 10.1074/jbc.M203717200.
    • (2002) J Biol Chem , vol.277 , pp. 27757-27764
    • D'Atri, F.1    Nadalutti, F.2    Citi, S.3
  • 26
    • 37549007949 scopus 로고    scopus 로고
    • Inducible overexpression of cingulin in stably transfected MDCK cells does not affect tight junction organization and gene expression
    • Paschoud S, Citi S. Inducible overexpression of cingulin in stably transfected MDCK cells does not affect tight junction organization and gene expression. Mol Membr Biol. 2008;25:1-13. doi: 10.1080/09687680701474009.
    • (2008) Mol Membr Biol , vol.25 , pp. 1-13
    • Paschoud, S.1    Citi, S.2
  • 27
    • 79251565586 scopus 로고    scopus 로고
    • Cingulin and paracingulin show similar dynamic behaviour, but are recruited independently to junctions
    • Paschoud S, Yu D, Pulimeno P, Jond L, Turner JR, Citi S. Cingulin and paracingulin show similar dynamic behaviour, but are recruited independently to junctions. Mol Membr Biol. 2011;28:123-135. doi: 10.3109/09687688.2010.538937.
    • (2011) Mol Membr Biol , vol.28 , pp. 123-135
    • Paschoud, S.1    Yu, D.2    Pulimeno, P.3    Jond, L.4    Turner, J.R.5    Citi, S.6
  • 28
    • 7944221328 scopus 로고    scopus 로고
    • Accumulation of plasma proteins in Purkinje cells as an indicator of blood-brain barrier breakdown
    • Ikegaya H, Heino J, Laaksonen H, Toivonen S, Kalimo H, Saukko P. Accumulation of plasma proteins in Purkinje cells as an indicator of blood-brain barrier breakdown. Forensic Sci Int. 2004;146:121-124. doi: 10.1016/j.forsciint.2004.06.024.
    • (2004) Forensic Sci Int , vol.146 , pp. 121-124
    • Ikegaya, H.1    Heino, J.2    Laaksonen, H.3    Toivonen, S.4    Kalimo, H.5    Saukko, P.6
  • 30
    • 12744253569 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors up-regulate the expression of tight junction proteins
    • Bordin M, D'Atri F, Guillemot L, Citi S. Histone deacetylase inhibitors up-regulate the expression of tight junction proteins. Mol Cancer Res. 2004;2:692-701.
    • (2004) Mol Cancer Res , vol.2 , pp. 692-701
    • Bordin, M.1    D'Atri, F.2    Guillemot, L.3    Citi, S.4
  • 31
    • 9444239778 scopus 로고    scopus 로고
    • Disruption of the cingulin gene does not prevent tight junction formation but alters gene expression
    • Guillemot L, Hammar E, Kaister C, Ritz J, Caille D, Jond L, Bauer C, Meda P, Citi S. Disruption of the cingulin gene does not prevent tight junction formation but alters gene expression. J Cell Sci. 2004;117(pt 22):5245-5256. doi: 10.1242/jcs.01399.
    • (2004) J Cell Sci , vol.117 , pp. 5245-5256
    • Guillemot, L.1    Hammar, E.2    Kaister, C.3    Ritz, J.4    Caille, D.5    Jond, L.6    Bauer, C.7    Meda, P.8    Citi, S.9
  • 33
    • 79955973354 scopus 로고    scopus 로고
    • Tight function zonula occludens-3 regulates cyclin D1-dependent cell proliferation
    • Capaldo CT, Koch S, Kwon M, Laur O, Parkos CA, Nusrat A. Tight function zonula occludens-3 regulates cyclin D1-dependent cell proliferation. Mol Biol Cell. 2011;22:1677-1685. doi: 10.1091/mbc.E10-08-0677.
    • (2011) Mol Biol Cell , vol.22 , pp. 1677-1685
    • Capaldo, C.T.1    Koch, S.2    Kwon, M.3    Laur, O.4    Parkos, C.A.5    Nusrat, A.6
  • 34
    • 84873599355 scopus 로고    scopus 로고
    • The junctional proteins cingulin and paracingulin modulate the expression of tight junction protein genes through GATA-4
    • Guillemot L, Spadaro D, Citi S. The junctional proteins cingulin and paracingulin modulate the expression of tight junction protein genes through GATA-4. PLoS One. 2013;8:e55873. doi: 10.1371/journal. pone.0055873.
    • (2013) PLoS One , vol.8
    • Guillemot, L.1    Spadaro, D.2    Citi, S.3
  • 35
    • 33749350938 scopus 로고    scopus 로고
    • Dual roles of tight junction-associated protein, zonula occludens-1, in sphingosine 1-phosphate-mediated endothelial chemotaxis and barrier integrity
    • Lee JF, Zeng Q, Ozaki H, Wang L, Hand AR, Hla T, Wang E, Lee MJ. Dual roles of tight junction-associated protein, zonula occludens-1, in sphingosine 1-phosphate-mediated endothelial chemotaxis and barrier integrity. J Biol Chem. 2006;281:29190-29200. doi: 10.1074/jbc.M604310200.
    • (2006) J Biol Chem , vol.281 , pp. 29190-29200
    • Lee, J.F.1    Zeng, Q.2    Ozaki, H.3    Wang, L.4    Hand, A.R.5    Hla, T.6    Wang, E.7    Lee, M.J.8
  • 38
    • 84922239992 scopus 로고    scopus 로고
    • Epithelial junctions and Rho family GTPases: The zonular signalosome
    • Citi S, Guerrera D, Spadaro D, Shah J. Epithelial junctions and Rho family GTPases: the zonular signalosome. Small GTPases. 2014;5:1-15. doi: 10.4161/21541248.2014.973760.
    • (2014) Small GTPases , vol.5 , pp. 1-15
    • Citi, S.1    Guerrera, D.2    Spadaro, D.3    Shah, J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.