A peptide to reduce pulmonary edema in a rat model of lung transplantation

PLoS ONE

Volumn 10, Issue 11, 2015, Pages

  Schossleitner, Klaudia ^a   Habertheuer, Andreas ^b   Finsterwalder, Richard ^a   Friedl, Heinz P ^a   Rauscher, Sabine ^b   Gröger, Marion ^b   Kocher, Alfred ^b   Wagner, Christine ^b   Wagner, Stephan N ^b   Fischer, Gottfried ^b   Schultz, Marcus J ^c   Wiedemann, Dominik ^b   Petzelbauer, Peter ^a  

^a Universitatsklinik fur Dermatologie   (Austria)

^b MEDICAL UNIVERSITY OF VIENNA   (Austria)

^c UNIVERSITY OF AMSTERDAM   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CINGULIN; INTERLEUKIN 6; MESSENGER RNA; SYNTHETIC PEPTIDE; TIGHT JUNCTION PROTEIN; UNCLASSIFIED DRUG; XIB13 PEPTIDE; ACTIN BINDING PROTEIN; CGN PROTEIN, HUMAN; MEMBRANE PROTEIN; PEPTIDE FRAGMENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD OXYGENATION; CONTROLLED STUDY; LUNG EDEMA; LUNG FIBROSIS; LUNG PERFUSION; LUNG TRANSPLANTATION; MAJOR HISTOCOMPATIBILITY COMPLEX; MALE; NECROSIS; NONHUMAN; RAT; RESPIRATORY TRACT INFLAMMATION; T LYMPHOCYTE; ADVERSE EFFECTS; AIR CONDITIONING; ANIMAL; DISEASE MODEL; DRUG EFFECTS; ORGAN PRESERVATION; PRIMARY GRAFT DYSFUNCTION; PULMONARY EDEMA; REAL TIME POLYMERASE CHAIN REACTION; VASCULAR RESISTANCE; WISTAR RAT;

ANIMALS; DISEASE MODELS, ANIMAL; LUNG TRANSPLANTATION; MALE; MEMBRANE PROTEINS; MICROFILAMENT PROTEINS; ORGAN PRESERVATION; PEPTIDE FRAGMENTS; PRIMARY GRAFT DYSFUNCTION; PULMONARY EDEMA; RATS; RATS, WISTAR; REAL-TIME POLYMERASE CHAIN REACTION; VASCULAR RESISTANCE; VENTILATION;

EID: 84951056581     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0142115     Document Type: Article

References (30)

1. Stehlik J, Edwards LB, Kucheryavaya AY, Benden C, Christie JD, Dobbels F, et al. The Registry of the International Society for Heart and Lung Transplantation: Twenty-eighth Adult Heart Transplant Report -2011. J Heart Lung Transplant. 2011; 30(10):1078-94. Epub 2011/10/04. doi: 10.1016/j.healun. 2011.08.003 PMID: 21962016
2. Yamane M, Liu M, Kaneda H, Uhlig S, Waddell TK, Keshavjee S. Reperfusion-induced gene expression profiles in rat lung transplantation. Am J Transplant. 2005; 5(9):2160-9. Epub 2005/08/13. PMID: 16095495
3. Gawlak G, Tian Y, O'Donnell JJ, 3rd, Tian X, Birukova AA, Birukov KG. Paxillin mediates stretchinduced Rho signaling and endothelial permeability via assembly of paxillin-p42/44MAPK-GEF-H1 complex. FASEB J. 2014; 28(7):3249-60. Epub 2014/04/08. doi: 10.1096/fj.13-245142 PMID: 24706358
4. Prakash A, Mesa KR, Wilhelmsen K, Xu F, Dodd-o JM, Hellman J. Alveolar macrophages and Toll-like receptor 4 mediate ventilated lung ischemia reperfusion injury in mice. Anesthesiology. 2012; 117 (4):822-35. Epub 2012/08/15. PMID: 22890118
5. Suzuki Y, Cantu E, Christie JD. Primary graft dysfunction. Semin Respir Crit Care Med. 2013; 34 (3):305-19. Epub 2013/07/04. doi: 10.1055/s-0033-1348474 PMID: 23821506
6. Neto ASF, R.R.; Rocha L.L.; Schultz M.J. Recent advances in mechanical ventilation in patients without acute respiratory distress syndrome. F1000Prime Rep. 2014(6: ).
7. Aigner C, Wisser W, Taghavi S, Lang G, Jaksch P, Czyzewski D, et al. Institutional experience with extracorporeal membrane oxygenation in lung transplantation. Eur J Cardiothorac Surg. 2007; 31 (3):468-73; discussion 73-4. Epub 2007/01/16. PMID: 17223352
8. Jaksch P, Wiedemann D, Augustin V, Murakozy G, Scheed A, Kocher AA, et al. Antithymocyte globulin induction therapy improves survival in lung transplantation for cystic fibrosis. Transpl Int. 2013; 26 (1):34-41. Epub 2012/11/14. doi: 10.1111/j.1432-2277.2012.01570.x PMID: 23145940
9. Bazzoni G, Dejana E. Endothelial cell-to-cell junctions: molecular organization and role in vascular homeostasis. Physiol Rev. 2004; 84(3):869-901. Epub 2004/07/23. PMID: 15269339
10. Chen W, Sharma R, Rizzo AN, Siegler JH, Garcia JG, Jacobson JR. Role of claudin-5 in the attenuation of murine acute lung injury by simvastatin. Am J Respir Cell Mol Biol. 2014; 50(2):328-36. Epub 2013/09/14. doi: 10.1165/rcmb.2013-0058OC PMID: 24028293
11. Kage H, Flodby P, Gao D, Kim YH, Marconett CN, DeMaio L, et al. Claudin 4 knockout mice: normal physiological phenotype with increased susceptibility to lung injury. Am J Physiol Lung Cell Mol Physiol. 2014; 307(7):L524-36. Epub 2014/08/12. doi: 10.1152/ajplung.00077.2014 PMID: 25106430
12. D'Atri F, Citi S. Cingulin interacts with F-actin in vitro. FEBS Lett. 2001; 507(1):21-4. Epub 2001/10/30. PMID: 11682052
13. Aijaz S, D'Atri F, Citi S, Balda MS, Matter K. Binding of GEF-H1 to the tight junction-associated adaptor cingulin results in inhibition of Rho signaling and G1/S phase transition. Dev Cell. 2005; 8(5):777-86. Epub 2005/05/04. PMID: 15866167
14. Terry SJ, Zihni C, Elbediwy A, Vitiello E, Leefa Chong San IV, Balda MS, et al. Spatially restricted activation of RhoA signalling at epithelial junctions by p114RhoGEF drives junction formation and morphogenesis. Nat Cell Biol. 2011; 13(2):159-66. Epub 2011/01/25. doi: 10.1038/ncb2156 PMID: 21258369
15. Birukov KG. Small GTPases in mechanosensitive regulation of endothelial barrier. Microvasc Res. 2009; 77(1):46-52. Epub 2008/10/22. doi: 10.1016/j.mvr.2008.09.006 PMID: 18938185
16. Goertz O, Lauer H, von der Lohe L, Lehnhardt M, Schossleitner K, Petzelbauer M, et al. Peptide XIB13 reduces capillary leak in a rodent burn model. Microvasc Res. 2014; 93:98-104. Epub 2014/04/29. doi: 10.1016/j.mvr.2014.04.003 PMID: 24769395
17. Habertheuer A, Kocher A, Laufer G, Petzelbauer P, Andreas M, Aharinejad S, et al. Innovative, simplified orthotopic lung transplantation in rats. J Surg Res. 2013; 185(1):419-25. Epub 2013/06/05. doi: 10. 1016/j.jss.2013.05.006 PMID: 23731688
18. Christie JD, Edwards LB, Kucheryavaya AY, Benden C, Dipchand AI, Dobbels F, et al. The Registry of the International Society for Heart and Lung Transplantation: 29th adult lung and heart-lung transplant report-2012. J Heart Lung Transplant. 2012; 31(10):1073-86. Epub 2012/09/15. doi: 10.1016/j.healun. 2012.08.004 PMID: 22975097
19. Christie JD, Kotloff RM, Ahya VN, Tino G, Pochettino A, Gaughan C, et al. The effect of primary graft dysfunction on survival after lung transplantation. Am J Respir Crit Care Med. 2005; 171(11):1312-6. Epub 2005/03/15. PMID: 15764726
20. Birukova AA, Fu P, Wu T, Dubrovskyi O, Sarich N, Poroyko V, et al. Afadin controls p120-catenin-ZO-1 interactions leading to endothelial barrier enhancement by oxidized phospholipids. J Cell Physiol. 2012; 227(5):1883-90. Epub 2011/07/07. doi: 10.1002/jcp.22916 PMID: 21732359
21. Birukova AA, Adyshev D, Gorshkov B, Bokoch GM, Birukov KG, Verin AD. GEF-H1 is involved in agonist-induced human pulmonary endothelial barrier dysfunction. Am J Physiol Lung Cell Mol Physiol. 2006; 290(3):L540-8. Epub 2005/11/01. PMID: 16257999
22. Tian Z, Dong B, Blackwell JW, Stewart PW, Egan TM. Effect of a vascular endothelial cadherin antagonist in a rat lung transplant model. Ann Thorac Surg. 2013; 95(3):1028-33. Epub 2013/01/22. doi: 10. 1016/j.athoracsur.2012.11.023 PMID: 23333062
23. Groger M, Pasteiner W, Ignatyev G, Matt U, Knapp S, Atrasheuskaya A, et al. Peptide Bbeta(15-42) preserves endothelial barrier function in shock. PLoS One. 2009; 4(4):e5391. Epub 2009/04/30. doi: 10.1371/journal.pone.0005391 PMID: 19401765
24. Su G, Hodnett M, Wu N, Atakilit A, Kosinski C, Godzich M, et al. Integrin alphavbeta5 regulates lung vascular permeability and pulmonary endothelial barrier function. Am J Respir Cell Mol Biol. 2007; 36 (3):377-86. Epub 2006/11/03. PMID: 17079779
25. Okazaki M, Kreisel F, Richardson SB, Kreisel D, Krupnick AS, Patterson GA, et al. Sphingosine 1-phosphate inhibits ischemia reperfusion injury following experimental lung transplantation. Am J Transplant. 2007; 7(4):751-8. Epub 2007/03/30. PMID: 17391120
26. Birukova AA, Singleton PA, Gawlak G, Tian X, Mirzapoiazova T, Mambetsariev B, et al. GRP78 is a novel receptor initiating a vascular barrier protective response to oxidized phospholipids. Mol Biol Cell. 2014; 25(13):2006-16. Epub 2014/05/16. doi: 10.1091/mbc.E13-12-0743 PMID: 24829380
27. Jing H, Yao J, Liu X, Fan H, Zhang F, Li Z, et al. Fish-oil emulsion (omega-3 polyunsaturated fatty acids) attenuates acute lung injury induced by intestinal ischemia-reperfusion through Adenosine 5'-monophosphate-activated protein kinase-sirtuin1 pathway. J Surg Res. 2014; 187(1):252-61. Epub 2013/11/16. doi: 10.1016/j.jss.2013.10.009 PMID: 24231522
28. Meng F, Meliton A, Moldobaeva N, Mutlu GM, Kawasaki Y, Akiyama T, et al. Asef mediates HGF protective effects against LPS-induced lung injury and endothelial barrier dysfunction. Am J Physiol Lung Cell Mol Physiol. 2014:ajplung 00170 2014. Epub 2014/12/30.
29. Sugimoto R, Okamoto T, Nakao A, Zhan J, Wang Y, Kohmoto J, et al. Nitrite reduces acute lung injury and improves survival in a rat lung transplantation model. Am J Transplant. 2012; 12(11):2938-48. Epub 2012/09/29. doi: 10.1111/j.1600-6143.2012.04169.x PMID: 23016570
30. Darwish I, Liles WC. Emerging therapeutic strategies to prevent infection-related microvascular endothelial activation and dysfunction. Virulence. 2013; 4(6):572-82. Epub 2013/07/19. doi: 10.4161/viru. 25740 PMID: 23863603