메뉴 건너뛰기




Volumn 58, Issue 7, 2015, Pages 1587-1600

Subcutaneous fat transplantation alleviates diet-induced glucose intolerance and inflammation in mice

(17)  Hocking, Samantha L a,b   Stewart, Rebecca L a   Brandon, Amanda E a   Suryana, Eurwin a   Stuart, Ella a   Baldwin, Emily M a   Kolumam, Ganesh A c   Modrusan, Zora c   Junutula, Jagath R c   Gunton, Jenny E d,e   Medynskyj, Michael f,g   Blaber, Sinead P f,g   Karsten, Elisabeth f,g   Herbert, Benjamin R f,g   James, David E a,h   Cooney, Gregory J a,i   Swarbrick, Michael M a,d,j  


Author keywords

Adipose tissue; Body fat distribution; Fatty liver; Glucose intolerance; Inflammation; Insulin resistance; Intra abdominal fat; Obesity; Subcutaneous fat; Visceral

Indexed keywords

ADIPONECTIN; GLUCOSE; GLYCOGEN; HEPATOCYTE NUCLEAR FACTOR 3BETA; INSULIN; INTERLEUKIN 10; INTERLEUKIN 12P70; INTERLEUKIN 13; INTERLEUKIN 17; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 5; INTERLEUKIN 6; LEPTIN; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; MONOCYTE CHEMOTACTIC PROTEIN 1; STAT3 PROTEIN; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; SUPPRESSOR OF CYTOKINE SIGNALING 3; TRIACYLGLYCEROL; TUMOR NECROSIS FACTOR ALPHA; CYTOKINE;

EID: 84931577296     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-015-3583-y     Document Type: Article
Times cited : (64)

References (47)
  • 1
    • 0028091785 scopus 로고
    • Regional adiposity and morbidity
    • COI: 1:STN:280:DyaK2M%2FisVCjsw%3D%3D, PID: 7938225
    • Kissebah AH, Krakower GR (1994) Regional adiposity and morbidity. Physiol Rev 74:761–811
    • (1994) Physiol Rev , vol.74 , pp. 761-811
    • Kissebah, A.H.1    Krakower, G.R.2
  • 2
    • 3242795814 scopus 로고    scopus 로고
    • Intra-abdominal fat is a major determinant of the National Cholesterol Education Program Adult Treatment Panel III criteria for the metabolic syndrome
    • COI: 1:CAS:528:DC%2BD2cXmtFGqtrk%3D, PID: 15277390
    • Carr DB, Utzschneider KM, Hull RL et al (2004) Intra-abdominal fat is a major determinant of the National Cholesterol Education Program Adult Treatment Panel III criteria for the metabolic syndrome. Diabetes 53:2087–2094
    • (2004) Diabetes , vol.53 , pp. 2087-2094
    • Carr, D.B.1    Utzschneider, K.M.2    Hull, R.L.3
  • 3
    • 0025299388 scopus 로고
    • Portal” adipose tissue as a generator of risk factors for cardiovascular disease and diabetes
    • COI: 1:STN:280:DyaK3czhsVymsQ%3D%3D, PID: 2196039
    • Bjorntorp P (1990) “Portal” adipose tissue as a generator of risk factors for cardiovascular disease and diabetes. Arteriosclerosis 10:493–496
    • (1990) Arteriosclerosis , vol.10 , pp. 493-496
    • Bjorntorp, P.1
  • 5
    • 34047155003 scopus 로고    scopus 로고
    • Visceral fat adipokine secretion is associated with systemic inflammation in obese humans
    • COI: 1:CAS:528:DC%2BD2sXktFChtbY%3D, PID: 17287468
    • Fontana L, Eagon JC, Trujillo ME, Scherer PE, Klein S (2007) Visceral fat adipokine secretion is associated with systemic inflammation in obese humans. Diabetes 56:1010–1013
    • (2007) Diabetes , vol.56 , pp. 1010-1013
    • Fontana, L.1    Eagon, J.C.2    Trujillo, M.E.3    Scherer, P.E.4    Klein, S.5
  • 6
    • 77953612080 scopus 로고    scopus 로고
    • Gluteofemoral body fat as a determinant of metabolic health
    • COI: 1:STN:280:DC%2BC3cvps1Kisw%3D%3D
    • Manolopoulos KN, Karpe F, Frayn KN (2010) Gluteofemoral body fat as a determinant of metabolic health. Int J Obes (Lond) 34:949–959
    • (2010) Int J Obes (Lond) , vol.34 , pp. 949-959
    • Manolopoulos, K.N.1    Karpe, F.2    Frayn, K.N.3
  • 7
    • 84867577535 scopus 로고    scopus 로고
    • Marked resistance of femoral adipose tissue blood flow and lipolysis to adrenaline in vivo
    • COI: 1:CAS:528:DC%2BC38XhsVOqtrzE, PID: 22898765
    • Manolopoulos KN, Karpe F, Frayn KN (2012) Marked resistance of femoral adipose tissue blood flow and lipolysis to adrenaline in vivo. Diabetologia 55:3029–3037
    • (2012) Diabetologia , vol.55 , pp. 3029-3037
    • Manolopoulos, K.N.1    Karpe, F.2    Frayn, K.N.3
  • 8
    • 0036381998 scopus 로고    scopus 로고
    • Adipose tissue as a buffer for daily lipid flux
    • COI: 1:CAS:528:DC%2BD38XntFegur0%3D, PID: 12242452
    • Frayn KN (2002) Adipose tissue as a buffer for daily lipid flux. Diabetologia 45:1201–1210
    • (2002) Diabetologia , vol.45 , pp. 1201-1210
    • Frayn, K.N.1
  • 9
    • 84908635308 scopus 로고    scopus 로고
    • Distinct developmental profile of lower-body adipose tissue defines resistance against obesity-associated metabolic complications
    • COI: 1:CAS:528:DC%2BC2cXhvVyhu7fP, PID: 24947352
    • Pinnick KE, Nicholson G, Manolopoulos KN et al (2014) Distinct developmental profile of lower-body adipose tissue defines resistance against obesity-associated metabolic complications. Diabetes 63:3785–3797
    • (2014) Diabetes , vol.63 , pp. 3785-3797
    • Pinnick, K.E.1    Nicholson, G.2    Manolopoulos, K.N.3
  • 10
    • 84908610920 scopus 로고    scopus 로고
    • A lifetime on the hips: programming lower-body fat to protect against metabolic disease
    • COI: 1:CAS:528:DC%2BC2cXhvVyhu7rO, PID: 25342727
    • Swarbrick MM (2014) A lifetime on the hips: programming lower-body fat to protect against metabolic disease. Diabetes 63:3575–3577
    • (2014) Diabetes , vol.63 , pp. 3575-3577
    • Swarbrick, M.M.1
  • 11
    • 9144223683 scopus 로고    scopus 로고
    • Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance
    • COI: 1:CAS:528:DC%2BD3sXhtVSmtLvI, PID: 14679177
    • Xu H, Barnes GT, Yang Q et al (2003) Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance. J Clin Invest 112:1821–1830
    • (2003) J Clin Invest , vol.112 , pp. 1821-1830
    • Xu, H.1    Barnes, G.T.2    Yang, Q.3
  • 12
    • 84863694517 scopus 로고    scopus 로고
    • Mechanisms of inflammatory responses in obese adipose tissue
    • COI: 1:CAS:528:DC%2BC38XhtlOjsrnP, PID: 22404118
    • Sun S, Ji Y, Kersten S, Qi L (2012) Mechanisms of inflammatory responses in obese adipose tissue. Annu Rev Nutr 32:261–286
    • (2012) Annu Rev Nutr , vol.32 , pp. 261-286
    • Sun, S.1    Ji, Y.2    Kersten, S.3    Qi, L.4
  • 13
    • 0348230958 scopus 로고    scopus 로고
    • Obesity is associated with macrophage accumulation in adipose tissue
    • COI: 1:CAS:528:DC%2BD3sXhtVSmtLvO, PID: 14679176
    • Weisberg SP, McCann D, Desai M, Rosenbaum M, Leibel RL, Ferrante AW Jr (2003) Obesity is associated with macrophage accumulation in adipose tissue. J Clin Invest 112:1796–1808
    • (2003) J Clin Invest , vol.112 , pp. 1796-1808
    • Weisberg, S.P.1    McCann, D.2    Desai, M.3    Rosenbaum, M.4    Leibel, R.L.5    Ferrante, A.W.6
  • 14
    • 33846026712 scopus 로고    scopus 로고
    • Obesity induces a phenotypic switch in adipose tissue macrophage polarization
    • COI: 1:CAS:528:DC%2BD2sXmvV2quw%3D%3D, PID: 17200717
    • Lumeng CN, Bodzin JL, Saltiel AR (2007) Obesity induces a phenotypic switch in adipose tissue macrophage polarization. J Clin Invest 117:175–184
    • (2007) J Clin Invest , vol.117 , pp. 175-184
    • Lumeng, C.N.1    Bodzin, J.L.2    Saltiel, A.R.3
  • 15
    • 84857985148 scopus 로고    scopus 로고
    • The cellular and signaling networks linking the immune system and metabolism in disease
    • COI: 1:CAS:528:DC%2BC38Xjt1OrtLc%3D, PID: 22395709
    • Osborn O, Olefsky JM (2012) The cellular and signaling networks linking the immune system and metabolism in disease. Nat Med 18:363–374
    • (2012) Nat Med , vol.18 , pp. 363-374
    • Osborn, O.1    Olefsky, J.M.2
  • 16
    • 84880617814 scopus 로고    scopus 로고
    • Association between specific adipose tissue CD4+ T-cell populations and insulin resistance in obese individuals
    • Fabbrini E, Cella M, McCartney SA et al (2013) Association between specific adipose tissue CD4+ T-cell populations and insulin resistance in obese individuals. Gastroenterology 145(366–374):e361–e363
    • (2013) Gastroenterology , vol.145 , Issue.366-374 , pp. 361-363
    • Fabbrini, E.1    Cella, M.2    McCartney, S.A.3
  • 17
    • 77950885686 scopus 로고    scopus 로고
    • The effects of salsalate on glycemic control in patients with type 2 diabetes: a randomized trial
    • PID: 20231565
    • Goldfine AB, Fonseca V, Jablonski KA, Pyle L, Staten MA, Shoelson SE (2010) The effects of salsalate on glycemic control in patients with type 2 diabetes: a randomized trial. Ann Intern Med 152:346–357
    • (2010) Ann Intern Med , vol.152 , pp. 346-357
    • Goldfine, A.B.1    Fonseca, V.2    Jablonski, K.A.3    Pyle, L.4    Staten, M.A.5    Shoelson, S.E.6
  • 18
    • 33847637510 scopus 로고    scopus 로고
    • Improved glucose tolerance in mice receiving intraperitoneal transplantation of normal fat tissue
    • COI: 1:STN:280:DC%2BD2srhslOhsw%3D%3D, PID: 17334653
    • Konrad D, Rudich A, Schoenle EJ (2007) Improved glucose tolerance in mice receiving intraperitoneal transplantation of normal fat tissue. Diabetologia 50:833–839
    • (2007) Diabetologia , vol.50 , pp. 833-839
    • Konrad, D.1    Rudich, A.2    Schoenle, E.J.3
  • 19
    • 41849094743 scopus 로고    scopus 로고
    • Studies of regional adipose transplantation reveal a unique and beneficial interaction between subcutaneous adipose tissue and the intra-abdominal compartment
    • COI: 1:STN:280:DC%2BD1c3jt1ehtA%3D%3D, PID: 18340430
    • Hocking SL, Chisholm DJ, James DE (2008) Studies of regional adipose transplantation reveal a unique and beneficial interaction between subcutaneous adipose tissue and the intra-abdominal compartment. Diabetologia 51:900–902
    • (2008) Diabetologia , vol.51 , pp. 900-902
    • Hocking, S.L.1    Chisholm, D.J.2    James, D.E.3
  • 20
    • 42649144463 scopus 로고    scopus 로고
    • Beneficial effects of subcutaneous fat transplantation on metabolism
    • COI: 1:CAS:528:DC%2BD1cXmtFeiurw%3D, PID: 18460332
    • Tran TT, Yamamoto Y, Gesta S, Kahn CR (2008) Beneficial effects of subcutaneous fat transplantation on metabolism. Cell Metab 7:410–420
    • (2008) Cell Metab , vol.7 , pp. 410-420
    • Tran, T.T.1    Yamamoto, Y.2    Gesta, S.3    Kahn, C.R.4
  • 21
    • 80054690480 scopus 로고    scopus 로고
    • Transplantation of non-visceral fat to the visceral cavity improves glucose tolerance in mice: investigation of hepatic lipids and insulin sensitivity
    • COI: 1:CAS:528:DC%2BC3MXht12js7vM, PID: 21805228
    • Foster MT, Shi H, Softic S, Kohli R, Seeley RJ, Woods SC (2011) Transplantation of non-visceral fat to the visceral cavity improves glucose tolerance in mice: investigation of hepatic lipids and insulin sensitivity. Diabetologia 54:2890–2899
    • (2011) Diabetologia , vol.54 , pp. 2890-2899
    • Foster, M.T.1    Shi, H.2    Softic, S.3    Kohli, R.4    Seeley, R.J.5    Woods, S.C.6
  • 22
    • 85008978659 scopus 로고    scopus 로고
    • Subcutaneous adipose tissue transplantation in diet-induced obese mice attenuates metabolic dysregulation while removal exacerbates it
    • PID: 23914298
    • Foster MT, Softic S, Caldwell J, Kohli R, de Kloet AD, Seeley RJ (2013) Subcutaneous adipose tissue transplantation in diet-induced obese mice attenuates metabolic dysregulation while removal exacerbates it. Physiol Rep 1:e00015
    • (2013) Physiol Rep , vol.1 , pp. 00015
    • Foster, M.T.1    Softic, S.2    Caldwell, J.3    Kohli, R.4    de Kloet, A.D.5    Seeley, R.J.6
  • 23
    • 72649089588 scopus 로고    scopus 로고
    • Acute or chronic upregulation of mitochondrial fatty acid oxidation has no net effect on whole-body energy expenditure or adiposity
    • COI: 1:CAS:528:DC%2BC3cXlt1Kksr8%3D, PID: 20074529
    • Hoehn KL, Turner N, Swarbrick MM et al (2010) Acute or chronic upregulation of mitochondrial fatty acid oxidation has no net effect on whole-body energy expenditure or adiposity. Cell Metab 11:70–76
    • (2010) Cell Metab , vol.11 , pp. 70-76
    • Hoehn, K.L.1    Turner, N.2    Swarbrick, M.M.3
  • 24
    • 0038708307 scopus 로고    scopus 로고
    • PTG gene deletion causes impaired glycogen synthesis and developmental insulin resistance
    • COI: 1:CAS:528:DC%2BD3sXjsFCrs7o%3D, PID: 12727934
    • Crosson SM, Khan A, Printen J, Pessin JE, Saltiel AR (2003) PTG gene deletion causes impaired glycogen synthesis and developmental insulin resistance. J Clin Invest 111:1423–1432
    • (2003) J Clin Invest , vol.111 , pp. 1423-1432
    • Crosson, S.M.1    Khan, A.2    Printen, J.3    Pessin, J.E.4    Saltiel, A.R.5
  • 25
    • 84886248233 scopus 로고    scopus 로고
    • Beta-cell ARNT is required for normal glucose tolerance in murine pregnancy
    • COI: 1:CAS:528:DC%2BC3sXhslWks7jF, PID: 24204824
    • Lau SM, Cha KM, Karunatillake A et al (2013) Beta-cell ARNT is required for normal glucose tolerance in murine pregnancy. PLoS One 8:e77419
    • (2013) PLoS One , vol.8 , pp. 77419
    • Lau, S.M.1    Cha, K.M.2    Karunatillake, A.3
  • 27
    • 27344435774 scopus 로고    scopus 로고
    • Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles
    • COI: 1:CAS:528:DC%2BD2MXht1ShtrnO, PID: 16199517
    • Subramanian A, Tamayo P, Mootha VK et al (2005) Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. Proc Natl Acad Sci U S A 102:15545–15550
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 15545-15550
    • Subramanian, A.1    Tamayo, P.2    Mootha, V.K.3
  • 28
    • 0038054341 scopus 로고    scopus 로고
    • PGC-1α-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes
    • COI: 1:CAS:528:DC%2BD3sXkvFSrs7o%3D, PID: 12808457
    • Mootha VK, Lindgren CM, Eriksson KF et al (2003) PGC-1α-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes. Nat Genet 34:267–273
    • (2003) Nat Genet , vol.34 , pp. 267-273
    • Mootha, V.K.1    Lindgren, C.M.2    Eriksson, K.F.3
  • 29
    • 77957677522 scopus 로고    scopus 로고
    • Chronically increased glucose uptake by adipose tissue leads to lactate production and improved insulin sensitivity rather than obesity in the mouse
    • COI: 1:CAS:528:DC%2BC3cXht1WltrrK, PID: 20623219
    • Munoz S, Franckhauser S, Elias I et al (2010) Chronically increased glucose uptake by adipose tissue leads to lactate production and improved insulin sensitivity rather than obesity in the mouse. Diabetologia 53:2417–2430
    • (2010) Diabetologia , vol.53 , pp. 2417-2430
    • Munoz, S.1    Franckhauser, S.2    Elias, I.3
  • 30
    • 84885662241 scopus 로고    scopus 로고
    • MEF2 is an in vivo immune-metabolic switch
    • COI: 1:CAS:528:DC%2BC3sXhsFensL7F, PID: 24075010
    • Clark RI, Tan SW, Pean CB et al (2013) MEF2 is an in vivo immune-metabolic switch. Cell 155:435–447
    • (2013) Cell , vol.155 , pp. 435-447
    • Clark, R.I.1    Tan, S.W.2    Pean, C.B.3
  • 31
    • 48249123867 scopus 로고    scopus 로고
    • Genome-wide occupancy of SREBP1 and its partners NFY and SP1 reveals novel functional roles and combinatorial regulation of distinct classes of genes
    • PID: 18654640
    • Reed BD, Charos AE, Szekely AM, Weissman SM, Snyder M (2008) Genome-wide occupancy of SREBP1 and its partners NFY and SP1 reveals novel functional roles and combinatorial regulation of distinct classes of genes. PLoS Genet 4:e1000133
    • (2008) PLoS Genet , vol.4 , pp. 1000133
    • Reed, B.D.1    Charos, A.E.2    Szekely, A.M.3    Weissman, S.M.4    Snyder, M.5
  • 32
    • 52749092267 scopus 로고    scopus 로고
    • Ablation of CD11c-positive cells normalizes insulin sensitivity in obese insulin resistant animals
    • COI: 1:CAS:528:DC%2BD1cXht1CitrfE, PID: 18840360
    • Patsouris D, Li PP, Thapar D, Chapman J, Olefsky JM, Neels JG (2008) Ablation of CD11c-positive cells normalizes insulin sensitivity in obese insulin resistant animals. Cell Metab 8:301–309
    • (2008) Cell Metab , vol.8 , pp. 301-309
    • Patsouris, D.1    Li, P.P.2    Thapar, D.3    Chapman, J.4    Olefsky, J.M.5    Neels, J.G.6
  • 33
    • 63249089427 scopus 로고    scopus 로고
    • Obesity-related upregulation of monocyte chemotactic factors in adipocytes: involvement of nuclear factor-kappaB and c-Jun NH2-terminal kinase pathways
    • COI: 1:CAS:528:DC%2BD1MXptVChuw%3D%3D, PID: 18835938
    • Jiao P, Chen Q, Shah S et al (2009) Obesity-related upregulation of monocyte chemotactic factors in adipocytes: involvement of nuclear factor-kappaB and c-Jun NH2-terminal kinase pathways. Diabetes 58:104–115
    • (2009) Diabetes , vol.58 , pp. 104-115
    • Jiao, P.1    Chen, Q.2    Shah, S.3
  • 34
    • 77957768699 scopus 로고    scopus 로고
    • Estrogen receptor-{beta}-selective ligands alleviate high-fat diet- and ovariectomy-induced obesity in mice
    • COI: 1:CAS:528:DC%2BC3cXht1aqtrnE, PID: 20657011
    • Yepuru M, Eswaraka J, Kearbey JD et al (2010) Estrogen receptor-{beta}-selective ligands alleviate high-fat diet- and ovariectomy-induced obesity in mice. J Biol Chem 285:31292–31303
    • (2010) J Biol Chem , vol.285 , pp. 31292-31303
    • Yepuru, M.1    Eswaraka, J.2    Kearbey, J.D.3
  • 35
    • 84870058819 scopus 로고    scopus 로고
    • Adaptive immunity in obesity and insulin resistance
    • COI: 1:CAS:528:DC%2BC38XhslahsLnJ, PID: 22847239
    • Sell H, Habich C, Eckel J (2012) Adaptive immunity in obesity and insulin resistance. Nat Rev Endocrinol 8:709–716
    • (2012) Nat Rev Endocrinol , vol.8 , pp. 709-716
    • Sell, H.1    Habich, C.2    Eckel, J.3
  • 36
    • 67649306416 scopus 로고    scopus 로고
    • PPAR gamma is highly expressed in F4/80(hi) adipose tissue macrophages and dampens adipose-tissue inflammation
    • COI: 1:CAS:528:DC%2BD1MXotF2nsrc%3D, PID: 19423085
    • Bassaganya-Riera J, Misyak S, Guri AJ, Hontecillas R (2009) PPAR gamma is highly expressed in F4/80(hi) adipose tissue macrophages and dampens adipose-tissue inflammation. Cell Immunol 258:138–146
    • (2009) Cell Immunol , vol.258 , pp. 138-146
    • Bassaganya-Riera, J.1    Misyak, S.2    Guri, A.J.3    Hontecillas, R.4
  • 37
    • 39549118715 scopus 로고    scopus 로고
    • Visceral adipose tissue inflammation accelerates atherosclerosis in apolipoprotein E-deficient mice
    • PID: 18212290
    • Ohman MK, Shen Y, Obimba CI et al (2008) Visceral adipose tissue inflammation accelerates atherosclerosis in apolipoprotein E-deficient mice. Circulation 117:798–805
    • (2008) Circulation , vol.117 , pp. 798-805
    • Ohman, M.K.1    Shen, Y.2    Obimba, C.I.3
  • 38
    • 84872480987 scopus 로고    scopus 로고
    • Interleukin-1beta regulates fat-liver crosstalk in obesity by auto-paracrine modulation of adipose tissue inflammation and expandability
    • COI: 1:CAS:528:DC%2BC3sXhsFyhtro%3D, PID: 23341960
    • Nov O, Shapiro H, Ovadia H et al (2013) Interleukin-1beta regulates fat-liver crosstalk in obesity by auto-paracrine modulation of adipose tissue inflammation and expandability. PLoS One 8:e53626
    • (2013) PLoS One , vol.8 , pp. 53626
    • Nov, O.1    Shapiro, H.2    Ovadia, H.3
  • 39
    • 78751494530 scopus 로고    scopus 로고
    • The portal theory supported by venous drainage-selective fat transplantation
    • COI: 1:CAS:528:DC%2BC3MXosVWiuw%3D%3D, PID: 20956499
    • Rytka JM, Wueest S, Schoenle EJ, Konrad D (2011) The portal theory supported by venous drainage-selective fat transplantation. Diabetes 60:56–63
    • (2011) Diabetes , vol.60 , pp. 56-63
    • Rytka, J.M.1    Wueest, S.2    Schoenle, E.J.3    Konrad, D.4
  • 40
    • 21244474452 scopus 로고    scopus 로고
    • Adipose tissues as an ancestral immune organ: site-specific change in obesity
    • COI: 1:CAS:528:DC%2BD2MXlvVWrtr0%3D, PID: 15953605
    • Caspar-Bauguil S, Cousin B, Galinier A et al (2005) Adipose tissues as an ancestral immune organ: site-specific change in obesity. FEBS Lett 579:3487–3492
    • (2005) FEBS Lett , vol.579 , pp. 3487-3492
    • Caspar-Bauguil, S.1    Cousin, B.2    Galinier, A.3
  • 41
    • 84879990867 scopus 로고    scopus 로고
    • Molecular pathways involved in the improvement of non-alcoholic fatty liver disease
    • PID: 23718963
    • Paz-Filho G, Mastronardi CA, Parker BJ et al (2013) Molecular pathways involved in the improvement of non-alcoholic fatty liver disease. J Mol Endocrinol 51:167–179
    • (2013) J Mol Endocrinol , vol.51 , pp. 167-179
    • Paz-Filho, G.1    Mastronardi, C.A.2    Parker, B.J.3
  • 42
    • 70349232891 scopus 로고    scopus 로고
    • Obesity predisposes to Th17 bias
    • COI: 1:CAS:528:DC%2BD1MXhtVKrtrrM, PID: 19662632
    • Winer S, Paltser G, Chan Y et al (2009) Obesity predisposes to Th17 bias. Eur J Immunol 39:2629–2635
    • (2009) Eur J Immunol , vol.39 , pp. 2629-2635
    • Winer, S.1    Paltser, G.2    Chan, Y.3
  • 43
    • 84907322144 scopus 로고    scopus 로고
    • HGK/MAP4K4 deficiency induces TRAF2 stabilization and Th17 differentiation leading to insulin resistance
    • COI: 1:CAS:528:DC%2BC2cXitVaksLnK, PID: 25098764
    • Chuang HC, Sheu WH, Lin YT et al (2014) HGK/MAP4K4 deficiency induces TRAF2 stabilization and Th17 differentiation leading to insulin resistance. Nat Commun 5:4602
    • (2014) Nat Commun , vol.5 , pp. 4602
    • Chuang, H.C.1    Sheu, W.H.2    Lin, Y.T.3
  • 44
    • 78650655167 scopus 로고    scopus 로고
    • IL-17 regulates adipogenesis, glucose homeostasis, and obesity
    • COI: 1:CAS:528:DC%2BC3cXhsVaqt7fP, PID: 21037091
    • Zuniga LA, Shen WJ, Joyce-Shaikh B et al (2010) IL-17 regulates adipogenesis, glucose homeostasis, and obesity. J Immunol 185:6947–6959
    • (2010) J Immunol , vol.185 , pp. 6947-6959
    • Zuniga, L.A.1    Shen, W.J.2    Joyce-Shaikh, B.3
  • 45
    • 84899490742 scopus 로고    scopus 로고
    • IL-17 signaling accelerates the progression of nonalcoholic fatty liver disease in mice
    • COI: 1:CAS:528:DC%2BC2cXntFCmtbk%3D, PID: 24115079
    • Harley IT, Stankiewicz TE, Giles DA et al (2014) IL-17 signaling accelerates the progression of nonalcoholic fatty liver disease in mice. Hepatology 59:1830–1839
    • (2014) Hepatology , vol.59 , pp. 1830-1839
    • Harley, I.T.1    Stankiewicz, T.E.2    Giles, D.A.3
  • 46
    • 79251589063 scopus 로고    scopus 로고
    • Elevated proinflammatory cytokine production by a skewed T cell compartment requires monocytes and promotes inflammation in type 2 diabetes
    • COI: 1:CAS:528:DC%2BC3MXjs1Kquw%3D%3D, PID: 21169542
    • Jagannathan-Bogdan M, McDonnell ME, Shin H et al (2011) Elevated proinflammatory cytokine production by a skewed T cell compartment requires monocytes and promotes inflammation in type 2 diabetes. J Immunol 186:1162–1172
    • (2011) J Immunol , vol.186 , pp. 1162-1172
    • Jagannathan-Bogdan, M.1    McDonnell, M.E.2    Shin, H.3
  • 47
    • 84857364150 scopus 로고    scopus 로고
    • Expression of NLRP3 inflammasome and T cell population markers in adipose tissue are associated with insulin resistance and impaired glucose metabolism in humans
    • COI: 1:CAS:528:DC%2BC38XivV2msrs%3D, PID: 22325453
    • Goossens GH, Blaak EE, Theunissen R et al (2012) Expression of NLRP3 inflammasome and T cell population markers in adipose tissue are associated with insulin resistance and impaired glucose metabolism in humans. Mol Immunol 50:142–149
    • (2012) Mol Immunol , vol.50 , pp. 142-149
    • Goossens, G.H.1    Blaak, E.E.2    Theunissen, R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.