Spontaneous transmembrane helix insertion thermodynamically mimics translocon-guided insertion

Nature Communications

Volumn 5, Issue , 2014, Pages

  Ulmschneider, Martin B ^a   Ulmschneider, Jakob P ^b   Schiller, Nina ^c   Wallace, B A ^d   Von Heijne, Gunnar ^c   White, Stephen H ^e  

^a Johns Hopkins University   (United States)

^b SHANGHAI JIAO TONG UNIVERSITY   (China)

^c STOCKHOLM UNIVERSITY   (Sweden)

^d UNIVERSITY OF LONDON   (United Kingdom)

^e UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

SYNTHETIC PEPTIDE; TRANSLOCON; ESCHERICHIA COLI PROTEIN; MEMBRANE PROTEIN; SEC61 PROTEIN; SECY PROTEIN, E COLI; SERINE PROTEINASE; TYPE I SIGNAL PEPTIDASE;

AQUEOUS SOLUTION; BIOASSAY; BIOPHYSICS; LIPID; MOLECULAR ANALYSIS; MUTATION; PROTEIN; THERMODYNAMICS;

ALPHA HELIX; AMINO ACID SEQUENCE; ARTICLE; COMPUTER MODEL; CONTROLLED STUDY; GENE INSERTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROGEN BOND; LIPID BILAYER; MOLECULAR DYNAMICS; POLYACRYLAMIDE GEL ELECTROPHORESIS; SOLID PHASE SYNTHESIS; THERMODYNAMICS; CELL MEMBRANE; METABOLISM; PROTEIN MOTIF; PROTEIN SECONDARY STRUCTURE; SPECTROSCOPY;

AMINO ACID MOTIFS; CELL MEMBRANE; ESCHERICHIA COLI PROTEINS; MEMBRANE PROTEINS; MOLECULAR DYNAMICS SIMULATION; PROTEIN STRUCTURE, SECONDARY; SERINE ENDOPEPTIDASES; SPECTRUM ANALYSIS; THERMODYNAMICS;

EID: 84955562310     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms5863     Document Type: Article

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