Development of Noviomimetics as C-Terminal Hsp90 Inhibitors

ACS Medicinal Chemistry Letters

Volumn 7, Issue 1, 2016, Pages 67-71

  Anyika, Mercy ^a   McMullen, Mason ^a   Forsberg, Leah K ^a   Dobrowsky, Rick T ^a   Blagg, Brian S J ^a  

^a UNIVERSITY OF KANSAS   (United States)

Author keywords

C terminal inhibition; Heat Shock Protein 70; Heat Shock Protein 90; neuroprotection; noviomimetics

Indexed keywords

2 CYCLOHEXENONE; 5,5 DIMETHYL 1,3 CYCLOHEXANEDIONE; AGLYCONE; CYCLOHEXANE DERIVATIVE; CYCLOHEXENE DERIVATIVE; CYCLOPENTANE DERIVATIVE; HEAT SHOCK PROTEIN 70; HEAT SHOCK PROTEIN 90; HEAT SHOCK PROTEIN 90 INHIBITOR; HEAT SHOCK TRANSCRIPTION FACTOR 1; NOVOBIOCIN; OSMIUM TETRAOXIDE;

ARTICLE; BINDING SITE; CARBOXY TERMINAL SEQUENCE; COLUMN CHROMATOGRAPHY; CONTROLLED STUDY; DIHYDROXYLATION; DRUG CONFORMATION; DRUG SYNTHESIS; HEAT SHOCK RESPONSE; ISOMER; MITSUNOBU REACTION; NEUROPROTECTION; PRIORITY JOURNAL; RACEMIC MIXTURE; SUBSTITUTION REACTION;

EID: 84955486109     PISSN: None     EISSN: 19485875     Source Type: Journal    
DOI: 10.1021/acsmedchemlett.5b00331     Document Type: Article

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