Biodistribution and toxicity of spherical aluminum oxide nanoparticles

Journal of Applied Toxicology

Volumn 36, Issue 3, 2016, Pages 424-433

  Park, Eun Jung ^a   Lee, Gwang Hee ^b   Yoon, Cheolho ^c   Jeong, Uiseok ^d   Kim, Younghun ^d   Cho, Myung Haing ^e   Kim, Dong Wan ^b  

^a Konyang University   (South Korea)

^b Korea University   (South Korea)

^c Korea Basic Science Institute (KBSI)   (South Korea)

^d Kwangwoon University   (South Korea)

^e Seoul National University   (South Korea)

Author keywords

Aluminum oxide hydroxide nanoparticles; Aluminum oxide nanoparticles; Distribution; Toxicity; Toxicity screening

Indexed keywords

ALPHA ALUMINUM OXIDE NANOPARTICLE; GAMMA ALUMINUM OXIDE HYDROXIDE NANOPARTICLE; GAMMA ALUMINUM OXIDE NANOPARTICLE; HYDROXYL GROUP; INTERLEUKIN 8; LACTATE DEHYDROGENASE; NANOPARTICLE; UNCLASSIFIED DRUG; ADENOSINE TRIPHOSPHATE; ALUMINUM HYDROXIDE; ALUMINUM OXIDE; ALUMINUM OXIDE HYDROXIDE; BIOLOGICAL MARKER; METAL NANOPARTICLE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOACCUMULATION; BRAIN; CELL LINE; CELL PROLIFERATION; CELL VIABILITY; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOKINE RELEASE; EMBRYO; HEART; HUMAN; HUMAN CELL; IN VITRO STUDY; KIDNEY; LEUKOCYTE; LIVER; LUNG; MALE; MOUSE; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; SKIN; SURFACE AREA; TRANSMISSION ELECTRON MICROSCOPY; ANIMAL; BIOASSAY; BLOOD; CARDIAC MUSCLE CELL; CELL SURVIVAL; COMPARATIVE STUDY; DOSE RESPONSE; DRUG EFFECTS; HEK293 CELL LINE; IMMUNOLOGY; INSTITUTE FOR CANCER RESEARCH MOUSE; METABOLISM; ORAL DRUG ADMINISTRATION; PARTICLE SIZE; RAT; RISK ASSESSMENT; SURFACE PROPERTY; TIME FACTOR; TISSUE DISTRIBUTION; TUMOR CELL LINE; ULTRASTRUCTURE;

ADENOSINE TRIPHOSPHATE; ADMINISTRATION, ORAL; ALUMINUM HYDROXIDE; ALUMINUM OXIDE; ANIMALS; BIOLOGICAL ASSAY; BIOMARKERS; BRAIN; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; HEK293 CELLS; HUMANS; INTERLEUKIN-8; KIDNEY; L-LACTATE DEHYDROGENASE; LIVER; LUNG; MALE; METAL NANOPARTICLES; MICE, INBRED ICR; MICROSCOPY, ELECTRON, TRANSMISSION; MYOCYTES, CARDIAC; NEUTROPHILS; PARTICLE SIZE; RATS; RISK ASSESSMENT; SKIN; SURFACE PROPERTIES; TIME FACTORS; TISSUE DISTRIBUTION;

EID: 84955461721     PISSN: 0260437X     EISSN: 10991263     Source Type: Journal    
DOI: 10.1002/jat.3233     Document Type: Article

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