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Volumn 14, Issue 2, 2016, Pages 234-242

Reciprocal Regulation between SIRT6 and miR-122 Controls Liver Metabolism and Predicts Hepatocarcinoma Prognosis

Author keywords

Fatty acid oxidation; miR 122; SIRT6

Indexed keywords

HISTONE H3; MICRORNA 122; SIRTUIN 6; FATTY ACID; MICRORNA; MIRN122 MICRORNA, HUMAN; SIRT6 PROTEIN, HUMAN; SIRTUIN;

EID: 84955337844     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2015.12.023     Document Type: Article
Times cited : (76)

References (40)
  • 1
    • 4644309196 scopus 로고    scopus 로고
    • The functions of animal microRNAs
    • Ambros V. The functions of animal microRNAs. Nature 2004, 431:350-355.
    • (2004) Nature , vol.431 , pp. 350-355
    • Ambros, V.1
  • 2
    • 0347444723 scopus 로고    scopus 로고
    • MicroRNAs: genomics, biogenesis, mechanism, and function
    • Bartel D.P. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 2004, 116:281-297.
    • (2004) Cell , vol.116 , pp. 281-297
    • Bartel, D.P.1
  • 3
    • 84888210254 scopus 로고    scopus 로고
    • MicroRNA-gene association as a prognostic biomarker in cancer exposes disease mechanisms
    • Ben-Hamo R., Efroni S. MicroRNA-gene association as a prognostic biomarker in cancer exposes disease mechanisms. PLoS Comput. Biol. 2013, 9:e1003351.
    • (2013) PLoS Comput. Biol. , vol.9
    • Ben-Hamo, R.1    Efroni, S.2
  • 4
    • 33744973775 scopus 로고    scopus 로고
    • Relief of microRNA-mediated translational repression in human cells subjected to stress
    • Bhattacharyya S.N., Habermacher R., Martine U., Closs E.I., Filipowicz W. Relief of microRNA-mediated translational repression in human cells subjected to stress. Cell 2006, 125:1111-1124.
    • (2006) Cell , vol.125 , pp. 1111-1124
    • Bhattacharyya, S.N.1    Habermacher, R.2    Martine, U.3    Closs, E.I.4    Filipowicz, W.5
  • 6
    • 23844523406 scopus 로고    scopus 로고
    • MiR-122, a mammalian liver-specific microRNA, is processed from hcr mRNA and may downregulate the high affinity cationic amino acid transporter CAT-1
    • Chang J., Nicolas E., Marks D., Sander C., Lerro A., Buendia M.A., Xu C., Mason W.S., Moloshok T., Bort R., et al. miR-122, a mammalian liver-specific microRNA, is processed from hcr mRNA and may downregulate the high affinity cationic amino acid transporter CAT-1. RNA Biol. 2004, 1:106-113.
    • (2004) RNA Biol. , vol.1 , pp. 106-113
    • Chang, J.1    Nicolas, E.2    Marks, D.3    Sander, C.4    Lerro, A.5    Buendia, M.A.6    Xu, C.7    Mason, W.S.8    Moloshok, T.9    Bort, R.10
  • 7
    • 70349976819 scopus 로고    scopus 로고
    • Loss of miR-122 expression in liver cancer correlates with suppression of the hepatic phenotype and gain of metastatic properties
    • Coulouarn C., Factor V.M., Andersen J.B., Durkin M.E., Thorgeirsson S.S. Loss of miR-122 expression in liver cancer correlates with suppression of the hepatic phenotype and gain of metastatic properties. Oncogene 2009, 28:3526-3536.
    • (2009) Oncogene , vol.28 , pp. 3526-3536
    • Coulouarn, C.1    Factor, V.M.2    Andersen, J.B.3    Durkin, M.E.4    Thorgeirsson, S.S.5
  • 13
    • 84866508022 scopus 로고    scopus 로고
    • RBM38 is a direct transcriptional target of E2F1 that limits E2F1-induced proliferation
    • Feldstein O., Ben-Hamo R., Bashari D., Efroni S., Ginsberg D. RBM38 is a direct transcriptional target of E2F1 that limits E2F1-induced proliferation. Mol. Cancer Res. 2012, 10:1169-1177.
    • (2012) Mol. Cancer Res. , vol.10 , pp. 1169-1177
    • Feldstein, O.1    Ben-Hamo, R.2    Bashari, D.3    Efroni, S.4    Ginsberg, D.5
  • 17
    • 84858195484 scopus 로고    scopus 로고
    • Liver-specific microRNA-122: Biogenesis and function
    • Jopling C. Liver-specific microRNA-122: Biogenesis and function. RNA Biol. 2012, 9:137-142.
    • (2012) RNA Biol. , vol.9 , pp. 137-142
    • Jopling, C.1
  • 18
    • 0033214237 scopus 로고    scopus 로고
    • The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms
    • Kaeberlein M., McVey M., Guarente L. The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms. Genes Dev. 1999, 13:2570-2580.
    • (1999) Genes Dev. , vol.13 , pp. 2570-2580
    • Kaeberlein, M.1    McVey, M.2    Guarente, L.3
  • 22
    • 77956315551 scopus 로고    scopus 로고
    • Hepatic-specific disruption of SIRT6 in mice results in fatty liver formation due to enhanced glycolysis and triglyceride synthesis
    • Kim H.S., Xiao C., Wang R.H., Lahusen T., Xu X., Vassilopoulos A., Vazquez-Ortiz G., Jeong W.I., Park O., Ki S.H., et al. Hepatic-specific disruption of SIRT6 in mice results in fatty liver formation due to enhanced glycolysis and triglyceride synthesis. Cell Metab. 2010, 12:224-236.
    • (2010) Cell Metab. , vol.12 , pp. 224-236
    • Kim, H.S.1    Xiao, C.2    Wang, R.H.3    Lahusen, T.4    Xu, X.5    Vassilopoulos, A.6    Vazquez-Ortiz, G.7    Jeong, W.I.8    Park, O.9    Ki, S.H.10
  • 27
    • 84883223984 scopus 로고    scopus 로고
    • Sirtuin-6-dependent genetic and epigenetic alterations are associated with poor clinical outcome in hepatocellular carcinoma patients
    • Marquardt J.U., Fischer K., Baus K., Kashyap A., Ma S., Krupp M., Linke M., Teufel A., Zechner U., Strand D., et al. Sirtuin-6-dependent genetic and epigenetic alterations are associated with poor clinical outcome in hepatocellular carcinoma patients. Hepatology 2013, 58:1054-1064.
    • (2013) Hepatology , vol.58 , pp. 1054-1064
    • Marquardt, J.U.1    Fischer, K.2    Baus, K.3    Kashyap, A.4    Ma, S.5    Krupp, M.6    Linke, M.7    Teufel, A.8    Zechner, U.9    Strand, D.10
  • 28
    • 84888255704 scopus 로고    scopus 로고
    • Regulation of LH receptor mRNA binding protein by miR-122 in rat ovaries
    • Menon B., Sinden J., Franzo-Romain M., Botta R.B., Menon K.M. Regulation of LH receptor mRNA binding protein by miR-122 in rat ovaries. Endocrinology 2013, 154:4826-4834.
    • (2013) Endocrinology , vol.154 , pp. 4826-4834
    • Menon, B.1    Sinden, J.2    Franzo-Romain, M.3    Botta, R.B.4    Menon, K.M.5
  • 33
    • 8644224064 scopus 로고    scopus 로고
    • Sir2 mediates longevity in the fly through a pathway related to calorie restriction
    • Rogina B., Helfand S.L. Sir2 mediates longevity in the fly through a pathway related to calorie restriction. Proc. Natl. Acad. Sci. USA 2004, 101:15998-16003.
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 15998-16003
    • Rogina, B.1    Helfand, S.L.2
  • 35
  • 36
    • 0035826271 scopus 로고    scopus 로고
    • Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans
    • Tissenbaum H.A., Guarente L. Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans. Nature 2001, 410:227-230.
    • (2001) Nature , vol.410 , pp. 227-230
    • Tissenbaum, H.A.1    Guarente, L.2
  • 39
    • 69249229772 scopus 로고    scopus 로고
    • The sirtuin SIRT6 deacetylates H3 K56Ac in vivo to promote genomic stability
    • Yang B., Zwaans B.M., Eckersdorff M., Lombard D.B. The sirtuin SIRT6 deacetylates H3 K56Ac in vivo to promote genomic stability. Cell Cycle 2009, 8:2662-2663.
    • (2009) Cell Cycle , vol.8 , pp. 2662-2663
    • Yang, B.1    Zwaans, B.M.2    Eckersdorff, M.3    Lombard, D.B.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.