Predicting all-cause mortality from basic physiology in the Framingham Heart Study

Aging Cell

Volumn 15, Issue 1, 2016, Pages 39-48

  Zhang, William B ^a   Pincus, Zachary ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Aging; Biodemography; Cumulative risk; Mortality; Physiology; Risk prediction

Indexed keywords

ADULT; AGE DISTRIBUTION; AGING; ARTICLE; BODY MASS; BODY WEIGHT; CARDIOVASCULAR DISEASE; CARDIOVASCULAR MORTALITY; CARDIOVASCULAR RISK; CLINICAL EFFECTIVENESS; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; ENVIRONMENTAL EXPOSURE; FEMALE; FOLLOW UP; FRAMINGHAM RISK SCORE; GLUCOSE BLOOD LEVEL; HUMAN; LIFESPAN; MAJOR CLINICAL STUDY; MALE; MEDICAL INFORMATION; PHYSIOLOGICAL PROCESS; PRIORITY JOURNAL; RISK ASSESSMENT; RISK FACTOR; SEX DIFFERENCE; SMOKING HABIT; SYSTOLIC BLOOD PRESSURE; AGED; BLOOD PRESSURE; COMPLICATION; MIDDLE AGED; MORTALITY; OBESITY; PHYSIOLOGY; PREDICTIVE VALUE;

ADULT; AGED; BLOOD PRESSURE; BODY MASS INDEX; BODY WEIGHT; CARDIOVASCULAR DISEASES; FEMALE; HUMANS; MALE; MIDDLE AGED; OBESITY; PREDICTIVE VALUE OF TESTS; RISK FACTORS;

EID: 84955215776     PISSN: 14749718     EISSN: 14749726     Source Type: Journal    
DOI: 10.1111/acel.12408     Document Type: Article

References (45)

1. Albala C, Yanez M, Devoto E, Sostin C, Zeballos L, Santos J (1996) Obesity as a protective factor for postmenopausal osteoporosis. Int. J. Obes. Relat. Metab. Disord. 20, 1027-1032.
2. Arbeev KG, Ukraintseva SV, Akushevich I, Kulminski AM, Arbeeva LS, Akushevich L, Culminskaya IV, Yashin AI (2011) Age trajectories of physiological indices in relation to healthy life course. Mech. Ageing Dev. 132, 93-102.
3. Assmann G, Cullen P, Schulte H (2002) Simple scoring scheme for calculating the risk of acute coronary events based on the 10-year follow-up of the prospective cardiovascular münster (procam) study. Circulation 105, 310-315.
4. Baker G (1975) Identical age-dependent patterns of enzyme changes in dipteran insects. Exp. Gerontol. 10, 231.
5. Baker GT III, Sprott RL (1988) Biomarkers of aging. Exp. Gerontol. 23, 223-239.
6. Belsky DW, Caspi A, Houts R, Cohen HJ, Corcoran DL, Danese A, Harrington H, Israel S, Levine ME, Schaefer JD, Sugden K, Williams B, Yashin AI, Poulton R, Moffitt TE (2015) Quantification of biological aging in young adults. Proc. Natl Acad. Sci. USA 112, E4104-E4110.
7. Collins R, Peto R, MacMahon S, Godwin J, Qizilbash N, Hebert P, Eberlein K, Taylor J, Hennekens C, Fiebach N (1990) Blood pressure, stroke, and coronary heart disease: part 2, short-term reductions in blood pressure: overview of randomised drug trials in their epidemiological context. Lancet 335, 827-838.
8. Cook NR, Cohen J, Hebert PR, Taylor JO, Hennekens CH (1995) Implications of small reductions in diastolic blood pressure for primary prevention. Arch. Intern. Med. 155, 701-709.
9. Costa PT, McCrae RR (1988) Measures and markers of biological aging: 'a great clamoring of fleeting significance'. Arch. Gerontol. Geriatr. 7, 211-214.
10. Dean W, Morgan RF (1988) In defense of the concept of biological aging measurement -current status. Arch. Gerontol. Geriatr. 7, 191-210.
11. Dietz WH (1994) Critical periods in childhood for the development of obesity. Am. J. Clin. Nutr. 59, 955-959.
12. Eckel RH, Krauss RM (1998) American heart association call to action: obesity as a major risk factor for coronary heart disease. Circulation 97, 2099-2100.
13. Goff DC, Lloyd-Jones DM, Bennett G, O'Donnell C, Coady S, Robinson J (2014) 2013 ACC/AHA guideline on the assessment of cardiovascular risk. J. Am. Coll. Cardiol. 63, 2935-2959.
14. Hansen M, Taubert S, Crawford D, Libina N, Lee SJ, Kenyon C (2007) Lifespan extension by conditions that inhibit translation in Caenorhabditis elegans. Aging Cell 6, 95-110.
15. Imai SI, Guarente L (2014) Nad+ and sirtuins in aging and disease. Trends Cell Biol. 24, 464-471.
16. Ingram DK (1988) Key questions in developing biomarkers of aging. Exp. Gerontol. 23, 429-434.
17. Ingram DK, Reynolds MA (1986) Assessing the predictive validity of psychomotor tests as measures of biological age in mice. Exp. Aging Res. 12, 155-162.
18. Jones OR, Scheuerlein A, Salguero-Gómez R, Camarda CG, Schaible R, Casper BB, Dahlgren JP, Ehrlén J, Garcíia MB, Menges ES, Quintana-Ascencio PF, Caswell H, Baudisch A, Vaupel JW (2014) Diversity of ageing across the tree of life. Nature 505, 169-173.
19. Kahn SE, Hull RL, Utzschneider KM (2006) Mechanisms linking obesity to insulin resistance and type 2 diabetes. Nature 444, 840-846.
20. Kannel WB (1996) Blood pressure as a cardiovascular risk factor: prevention and treatment. JAMA 275, 1571-1576.
21. Kannel WB, Feinleib M, McNamara PM, Garrison RJ, Castelli WP (1979) An investigation of coronary heart disease in families: the Framingham Offspring Study. Am. J. Epidemiol. 110, 281-290.
22. Kenyon C, Chang J, Gensch E, Rudner A, Tabtiang R (1993) A C. elegans mutant that lives twice as long as wild type. Nature 366, 461-464.
23. Kirkwood TB (2005) Understanding the odd science of aging. Cell 120, 437-447.
24. Kulminski A, Ukraintseva SV, Akushevich I, Arbeev KG, Land K, Yashin AI (2007) Accelerated accumulation of health deficits as a characteristic of aging. Exp. Gerontol. 42, 963-970.
25. Lakowski B, Hekimi S (1996) Determination of life-span in Caenorhabditis elegans by four clock genes. Science 272, 1010-1013.
26. Li Y, Wang WJ, Cao H, Lu J, Wu C, Hu FY, Guo J, Zhao L, Yang F, Zhang YX, Li W, Zheng GY, Cui H, Chen X, Zhu Z, He H, Dong B, Mo X, Zeng Y, Tian XL (2009) Genetic association of FOXO1A and FOXO3A with longevity trait in han chinese populations. Hum. Mol. Genet. 18, 4897-4904.
27. Lloyd-Jones DM, Wilson PW, Larson MG, Beiser A, Leip EP, D'Agostino RB, Levy D (2004) Framingham risk score and prediction of lifetime risk for coronary heart disease. Am. J. Cardiol. 94, 20-24.
28. Ludwig FC, Smoke ME (1980) The measurement of biological age. Exp. Aging Res. 6, 497-522.
29. Luft FC, Mervaala E, Müller DN, Gross V, Schmidt F, Park JK, Schmitz C, Lippoldt A, Breu V, Dechend R, Dragun D, Schneider W, Ganten D, Haller H (1999) Hypertension-induced end-organ damage a new transgenic approach to an old problem. Hypertension 33, 212-218.
30. Lunetta KL, D'Agostino RB, Karasik D, Benjamin EJ, Guo CY, Govindaraju R, Kiel DP, Kelly-Hayes M, Massaro JM, Pencina MJ, Seshadri S, Murabito JM (2007) Genetic correlates of longevity and selected age-related phenotypes: a genome-wide association study in the Framingham Study. BMC Med. Genet. 8, S13.
31. Mitnitski A, Song X, Skoog I, Broe GA, Cox JL, Grunfeld E, Rockwood K (2005) Relative fitness and frailty of elderly men and women in developed countries and their relationship with mortality. J. Am. Geriatr. Soc. 53, 2184-2189.
32. Mitnitski A, Bao L, Rockwood K (2006) Going from bad to worse: a stochastic model of transitions in deficit accumulation, in relation to mortality. Mech. Ageing Dev. 127, 490-493.
33. Mitnitski A, Song X, Rockwood K (2013) Assessing biological aging: the origin of deficit accumulation. Biogerontology 14, 709-717.
34. Pan KZ, Palter JE, Rogers AN, Olsen A, Chen D, Lithgow GJ, Kapahi P (2007) Inhibition of mRNA translation extends lifespan in Caenorhabditis elegans. Aging Cell 6, 111-119.
35. Satoh A, Imai SI (2014) Systemic regulation of mammalian ageing and longevity by brain sirtuins. Nat. Commun. 5, 4211.
36. Sesso HD, Cook NR, Buring JE, Manson JE, Gaziano JM (2008) Alcohol consumption and the risk of hypertension in women and men. Hypertension 51, 1080-1087.
37. Vasan RS, Larson MG, Leip EP, Evans JC, O'Donnell CJ, Kannel WB, Levy D (2001) Impact of high-normal blood pressure on the risk of cardiovascular disease. N. Engl. J. Med. 345, 1291-1297.
38. Vaupel JW, Carey JR, Christensen K, Johnson TE, Yashin AI, Holm NV, Iachine IA, Kannisto V, Khazaeli AA, Liedo P, Longo VD, Zeng Y, Manton KG, Curtsinger JW (1998) Biodemographic trajectories of longevity. Science 280, 855-860.
39. Willcox BJ, Donlon TA, He Q, Chen R, Grove JS, Yano K, Masaki KH, Willcox DC, Rodriguez B, Curb JD (2008) FOXO3A genotype is strongly associated with human longevity. Proc. Natl Acad. Sci. USA 105, 13987-13992.
40. Wilson DL (1988) Aging hypothesis, aging markers and the concept of biological age. Exp. Gerontol. 23, 435-438.
41. Wilson PW, D'Agostino RB, Levy D, Belanger AM, Silbershatz H, Kannel WB (1998) Prediction of coronary heart disease using risk factor categories. Circulation 97, 1837-1847.
42. Yashin AI, Akushevich IV, Arbeev KG, Akushevich L, Ukraintseva SV, Kulminski A (2006) Insights on aging and exceptional longevity from longitudinal data: novel findings from the Framingham Heart Study. Age 28, 363-374.
43. Yashin AI, Arbeev KG, Akushevich I, Kulminski A, Akushevich L, Ukraintseva SV (2007) Stochastic model for analysis of longitudinal data on aging and mortality. Math. Biosci. 208, 538-551.
44. Yashin AI, Arbeev KG, Akushevich I, Ukraintseva SV, Kulminski A, Arbeeva LS, Culminskaya I (2010) Exceptional survivors have lower age trajectories of blood glucose: lessons from longitudinal data. Biogerontology 11, 257-265.
45. Yashin AI, Arbeev KG, Wu D, Arbeeva LS, Kulminski A, Akushevich I, Culminskaya I, Stallard E, Ukraintseva SV (2013) How lifespan associated genes modulate aging changes: lessons from analysis of longitudinal data. Front. Genet. 4, 3.