ω-Amidase: An underappreciated, but important enzyme in l-glutamine and l-asparagine metabolism; Relevance to sulfur and nitrogen metabolism, tumor biology and hyperammonemic diseases

Amino Acids

Volumn 48, Issue 1, 2016, Pages 1-20

  Cooper, Arthur J L ^a   Shurubor, Yevgeniya I ^b,c   Dorai, Thambi ^a   Pinto, John T ^a   Isakova, Elena P ^c   Deryabina, Yulia I ^c   Denton, Travis T ^d   Krasnikov, Boris F ^a,c  

^a NEW YORK MEDICAL COLLEGE   (United States)

^b FEIL FAMILY BRAIN AND MIND RESEARCH INSTITUTE   (United States)

^c BACH INSTITUTE OF BIOCHEMISTRY   (Russian Federation)

^d WASHINGTON STATE UNIVERSITY   (United States)

Author keywords

Asparagine transaminase; Glutamine transaminase; Kynurenine aminotransferase; Nitrilase like protein (Nit2); Ketoglutaramate; Ketosuccinamate; Amidase

Indexed keywords

2 HYDROXYGLUTARIC ACID; 2 OXOGLUTARIC ACID; 2 OXOISOCAPROIC ACID; 4 HYDROXYBUTYRIC ACID; ALPHA AMINO ACID; AMIDASE; AMINOTRANSFERASE; ASPARAGINASE; ASPARAGINE; BIOLOGICAL MARKER; CASPASE 3; CYSTEINE CONJUGATE BETA LYASE; GLUTAMATE DEHYDROGENASE; GLUTAMINASE; GLUTAMINE; GLUTAMINE PHENYLPYRUVATE AMINOTRANSFERASE; GLUTAMINE TRANSAMINASE L; NITRILASE; NITRILASE LIKE PROTEIN 1; NITRILASE LIKE PROTEIN 2; OMEGA AMIDASE; OXALOACETIC ACID; SULFUR; UNCLASSIFIED DRUG; NITROGEN; OMEGA-AMIDASE;

AMINO ACID METABOLISM; APOPTOSIS; BREAST CANCER; CANCER GROWTH; CATALYSIS; CELL DIVISION; COLON CANCER; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME KINETICS; ENZYME LOCALIZATION; ENZYME SUBSTRATE; HUMAN; HYDROLYSIS; HYPERAMMONEMIA; MALIGNANT NEOPLASTIC DISEASE; NITROGEN METABOLISM; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN STRUCTURE; PROTEIN TRANSPORT; PROTEOMICS; REVIEW; SIGNAL TRANSDUCTION; TRANSAMINATION; ANIMAL; CHEMISTRY; ENZYMOLOGY; GENETICS; METABOLISM; NEOPLASM;

AMIDOHYDROLASES; ANIMALS; ASPARAGINE; GLUTAMINE; HUMANS; HYPERAMMONEMIA; NEOPLASMS; NITROGEN; SULFUR;

EID: 84955201018     PISSN: 09394451     EISSN: 14382199     Source Type: Journal    
DOI: 10.1007/s00726-015-2061-7     Document Type: Review

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