On the mechanism of oleate transport across human brain microvessel endothelial cells

Journal of Neurochemistry

Volumn 110, Issue 3, 2009, Pages 1049-1057

  Mitchell, Ryan W ^a   Edmundson, Carmen L ^a   Miller, Donald W ^a   Hatch, Grant M ^a  

^a UNIVERSITY OF MANITOBA   (Canada)

Author keywords

Blood brain barrier; Fatty acid translocase CD36; Fatty acid transport protein 1; Human brain microvessel endothelial cells

Indexed keywords

ALBUMIN; BOVINE SERUM ALBUMIN; CD36 ANTIGEN; FATTY ACID TRANSPORTER; OLEIC ACID; PHLORETIN;

ARTICLE; BLOOD BRAIN BARRIER; BRAIN MICROCIRCULATION; CAPILLARY ENDOTHELIUM; CELL MEMBRANE PERMEABILITY; CENTRAL NERVOUS SYSTEM; ENDOTHELIUM CELL; FATTY ACID TRANSPORT; HUMAN; HUMAN CELL; MONOLAYER CULTURE; PRIORITY JOURNAL; TRANSCYTOSIS;

BIOLOGICAL TRANSPORT; BLOOD-BRAIN BARRIER; BRAIN; CELLS, CULTURED; ENDOTHELIAL CELLS; ENDOTHELIUM, VASCULAR; FATTY ACID TRANSPORT PROTEINS; HUMANS; MICROVESSELS; OLEIC ACID;

BOVINAE;

EID: 67650434926     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2009.06199.x     Document Type: Article

References (59)

1. Abbott N. J. (2005) Dynamics of CNS barriers: evolution, differentiation, and modulation. Cell. Mol. Neurobiol. 25, 5 23. (Pubitemid 40558582)
2. Abbott N. J., Rönnbäck L. Hansson E. (2006) Astrocyte-endothelial interactions at the blood-brain barrier. Nat. Rev. Neurosci. 7, 41 53. (Pubitemid 41828930)
3. Abumrad N., Harmon C. Ibrahimi A. (1998) Membrane transport of long-chain fatty acids: evidence for a facilitated process. J. Lipid Res. 39, 2309 2318. (Pubitemid 29006294)
4. Abumrad N., Coburn C. Ibrahimi A. (1999) Membrane proteins implicated in long-chain fatty acid uptake by mammalian cells: CD36, FATP and FABPm. Biochem. Biophys. Acta. 1441, 4 13. (Pubitemid 29469432)
5. el-Bacha R. S. Minn A. (1999) Drug metabolizing enzymes in cereebrovascular endothelial cells afford a metabolic protection to the brain. Cell. Mol. Biol. 45, 15 23.
6. Bell J. G., Sargent J. R., Tocher D. R. Dick J. R. (2000) Red blood cell fatty acid compositions in a patient with autistic spectrum disorder: a characteristics abnormality in neurodevelopmental disorders?. Prostaglandins Leukot. Essent. Fatty Acids 63, 21 25.
7. Brightman M. W. Reese T. S. (1969) Junctions between intimately apposed cell membranes in the vertebrate brain. J. Cell Biol. 40, 648 677.
8. Chen C. T., Green J. T., Orr S. K. Bazinet R. P. (2008) Regulation of brain polyunsaturated fatty acid uptake and turnover. Prostaglandins Leukot. Essent. Fatty Acids 79, 85 91.
9. Clayton E. H., Hanstock T. L., Hirneth S. J., Kable C. J., Garg M. L. Hazell P. L. (2008) Long-chain omega-3 polyunsaturated Fatty acids in the blood of children and adolescents with juvenile bipolar disorder. Lipids 43, 1031 1038.
10. Cuzner M. L. Davison A. N. (1968) The lipid composition of rat brain myelin and subcellular fractions during development. Biochem. J. 106, 29 34.
11. Dhopeshwarkar G. A. (1973) Uptake and transport of fatty acids into the brain and the role of the blood-brain barrier system. Adv. Lipid Res. 11, 109 142.
12. Di Terlizzi R. Platt S. (2006) The function, composition and analysis of cerebrospinal fluid in companion animals: part l - function and composition. Vet. J. 172, 422 431. (Pubitemid 44575920)
13. Doege H. Stahl A. (2005) Protein-mediated fatty acid uptake: novel insights from in vivo models. Physiology 21, 259 268.
14. Drewes L. R. (2001) Molecular architecture of the brain microvasculature. J. Mol. Neurosci. 16, 93 98.
15. Dutta-Roy A. K. (2000) Cellular uptake of long-chain fatty acids: role of membrane associated fatty-acid-binding/transport proteins. Cell. Mol. Life Sci. 57, 1360 1372. (Pubitemid 30777884)
16. Edmond J. (2001) Essential polyunsaturated fatty acids and the barrier to the brain: the components of a model for transport. J. Mol. Neurosci. 16, 181 193. (Pubitemid 32664778)
17. Edmond J., Korsak R. A., Morrow J. W., Torok-Both G. Catlin D. (1991) Dietary cholesterol and the origin of cholesterol in brain of developing rats. J. Nutr. 121, 1323 1330.
18. Edmond J., Higa T. A., Korsak R. A., Bergner E. A. Lee W. N. P. (1998) Fatty acid transport and utilization for the developing brain. J. Neurochem. 70, 1227 1234. (Pubitemid 28113658)
19. Frohnert B. I. Bernlohr D. A. (2000) Regulation of fatty acid transporters in mammalian cells. Prog. Lipid Res. 39, 83 107. (Pubitemid 30145443)
20. Groener J. E., Bax W. Poorthuis B. J. (1996) Metabolic fate of oleate derived from lysosomal degradation of cholesteryl oleate in human fibroblasts. J. Lipid Res. 37, 2271 2279. (Pubitemid 26427440)
21. Hamilton J. A. (1998) Fatty acid transport: difficult or easy? J. Lipid Res. 39, 467 481. (Pubitemid 28158391)
22. Hamilton J. A. (2007) New insights into the roles of proteins and lipids in membrane transport of fatty acids. Prostaglandins Leukot. Essent. Fatty Acids 77, 355 361. (Pubitemid 350198863)
23. Hamilton J. A. Brunaldi K. (2007) A model for fatty acid transport into the brain. J. Mol. Neurosci. 33, 12 17. (Pubitemid 47574951)
24. Harmon C. M. Abumrad N. A. (1993) Binding of sulfosuccinimidyl fatty acids to adipocyte membrane proteins: isolation and aminoterminal sequence of an 88-kDa protein implicated in transport of long-chain fatty acids. J. Membr. Biol. 133, 43 49. (Pubitemid 23116346)
25. Hatch G. M. McClarty G. (1996) Regulation of cardiolipin biosynthesis in H9c2 cardiac myoblasts by cytidine 5′-triphosphate. J. Biol. Chem. 271, 25810 25816. (Pubitemid 26347409)
26. Hatch G. M., Smith A. J., Xu F. Y., Hall A. M. Bernlohr D. A. (2002) FATP1 channels exogenous FA into 1,2,3-triacyl-sn-glycerol and down-regulates sphingomyelin and cholesterol metabolism in growing 293 cells. J. Lipid Res. 43, 1380 1389.
27. Hawkins B. Davis T. P. (2005) The blood-brain barrier/neurovascular unit in health and disease. Pharmacol. Rev. 57, 173 185. (Pubitemid 41043883)
28. Hibbeln J. (1998) Fish consumption and major depression. Lancet 351, 1213.
29. Horrobin D. F. (1999) A possible role for phospholipases in autism and Asperger's syndrome, in Phospholipid Spectrum Disorder in Psychiatry (Peet M., Glen I. Horrobin D. F., eds pp. 271 273. Marius Press, Carnforth.
30. Hui T. Y. Bernlohr D. A. (1997) Fatty acid transporters in animal cells. Front. Biosci. 2, 222 231.
31. Husemann J., Loike J. D., Anankov R., Febbraio M. Silverstein S. C. (2002) Scavenger receptors in neurobiology and neuropathology: their role on microglia and other cells of the nervous system. Glia 40, 195 205. (Pubitemid 35337377)
32. Kamp F., Westerhoff H. V. Hamilton J. A. (1993) Movement of fatty acids, fatty acid analogues, and bile acids across phospholipid bilayers. Biochemistry 32, 11074 11086. (Pubitemid 23332014)
33. Kamp F., Zakim D., Zhang F. L., Noy N. Hamilton J. A. (1995) Fatty acid flip-flop in phospholipid bilayers is extremely fast. Biochemistry 34, 11928 11937.
34. Khan E. (2005) An examination of the blood brain barrier in health and disease. Br. J. Nurs. 14, 509 513.
35. Kramer S. D., Hurley J. A., Abbott N. J. Begley D. J. (2002) Lipids in blood-brain barrier models in vitro I: thin-layer chromatography and high-performance liquid chromatography for the analysis of lipid classes and long-chain polyunsaturated fatty acids. In Vitro Cell. Dev. Biol. Anim. 38, 557 565. (Pubitemid 36666241)
36. Lowry O. H., Rosebrough N. J., Farr A. L. Randall R. J. (1951) Protein measurement with the Folin phenol reagent. J. Biol. Chem. 193, 265 275.
37. Marshall T. Williams K. M. (2000) Protein determination in cerebrospinal fluid by protein dye-binding assay. Br. J. Biomed. Sci. 57, 281 286. (Pubitemid 32099388)
38. Morell P. Toews A. D. (1996) Biochemistry of lipids, in Handbook of Clinical Neurology (Moser H. W., ed.), Vol. 22: Neurodystrophies and Neurolipidoses, pp. 33 49. Elsevier, Amsterdam.
39. Pardridge W. M. Mietus L. J. (1980) Palmitate and cholesterol transport through the blood-brain barrier. J. Neurochem. 34, 463 466. (Pubitemid 10172303)
40. Pardridge W. M., Connor J. D. Crawford I. L. (1975) Permeability changes in the blood brain barrier causes and consequences. CRC Crit. Rev. Toxicol. 3, 159 199.
41. Pawels E. K. Volterrani D. (2008) Fatty acid facts, Part l. Essential fatty acids as treatment for depression, or food for mood? Drug News Perspect. 21, 446 451.
42. Pries A. R. Kuebler K. M. (2006) Normal endothelium. Handb. Exp. Pharmacol. 176, 1 40.
43. Rapoport S. I. (2008) Brain arachidonic and docosahexaenoic acid cascades are selectively altered by drugs, diet and disease. Prostaglandins Leukot. Essent. Fatty Acids 79, 153 156.
44. Rapoport S. I., Chang M. C. J. Spector A. A. (2001) Delivery and turnover of plasma-derived essential PUFAs in mammalian brain. J. Lipid Res. 42, 678 685. (Pubitemid 32507167)
45. Reese T. S. Karnovsky M. J. (1967) Fine structural localization of a blood-brain barrier to exogenous peroxidase. J. Cell Biol. 34, 207 217.
46. Schaffer J. E. (1996) A novel adipocyte long chain fatty acid transport protein. Eur. J. Med. Res. 1, 176 180.
47. Schaffer J. E. (2002) Fatty acid transport: the roads taken. Am. J. Physiol. Endocrinol. Metab. 282, E239 E246.
48. Schaffer J. E. Lodish H. F. (1994) Expression cloning and characterization of a novel adipocyte long chain fatty acid transport protein. Cell 79, 427 436. (Pubitemid 24346058)
49. Seelig A. (2007) The role of size and charge for blood-brain barrier permeation of drugs and fatty acids. J. Mol. Neurosci. 33, 32 41. (Pubitemid 47574956)
50. Simopoulos A. (1989) Summary of the NATO advanced research workshop on dietary omega 3 and omega 6 fatty acids: biological effects and nutritional essentially. J. Nutr. 119, 521 528.
51. Söderberg M., Edlund C., Kridtensson K. Dallner G. (1991) Fatty acid composition of brain phospholipids in aging and in Alzheimer's disease. Lipids 26, 421 425.
52. Spector R. (1988) Fatty acid transport through the blood-brain barrier. J. Neurochem. 50, 639 643. (Pubitemid 18042340)
53. Spector A. A. (2001) Plasma free fatty acid and lipoproteins as sources of polyunsaturated fatty acid for the brain. J. Mol. Neurosci. 16, 159 165. (Pubitemid 32664775)
54. Stoll A. L., Severus W. E., Freeman M. P., Rueter S., Zboyan H. A., Diamond E., Cress K. K. Marangell L. B. (1999) Omega 3 fatty acids in bipolar disorder: a preliminary double-blind, placebo-controlled trial. Arch. Gen. Psychiatr. 56, 407 412. (Pubitemid 29215428)
55. Storch J. Corsico B. (2008) The emerging functions and mechanisms of mammalian fatty acid-binding proteins. Ann. Rev. Nutr. 28, 73 95.
56. Sztriha L. Betz L. (1991) Oleic acid reversibly opens the blood-brain barrier. Brain Res. 550, 257 262.
57. Verkman A. S. Solomon A. K. (1982) A stepwise mechanism for the permeation of phloretin through a lipid bilayer. J. Gen. Physiol. 80, 557 581. (Pubitemid 12037505)
58. Watkins P. A., Hamilton J. A., Leaf A., Spector A. A., Moore S. A., Anderson R. E., Moser H. W., Noetzel M. J. Katz R. (2001) Brain uptake and utilization of fatty acids: applications to peroxisomal biogenesis diseases. J. Mol. Neurosci. 16, 87 92. (Pubitemid 32664766)
59. Williams W. M., Chang M. C., Hayakawa T., Grange E. Rapoport S. I. (1997) In vivo incorporation from plasma of radiolabeled palmitate and arachidonate into rat brain microvessels. Microvasc. Res. 53, 163 166. (Pubitemid 27202433)