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Volumn 3, Issue 5, 2002, Pages 230-236

Stem cell defect in aplastic anemia: Reduced long term culture-initiating cells (LTC-IC) in CD34+ cells isolated from aplastic anemia patient bone marrow

Author keywords

Aplastic anemia; CD34; Long term bone marrow culture; Long term culture initiating cells (LTC IC)

Indexed keywords

AUTOANTIGEN; CD34 ANTIGEN; CYCLOSPORIN A; DANAZOL; GRANULOCYTE COLONY STIMULATING FACTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; HEPARIN; IMMUNOSUPPRESSIVE AGENT; METHYLPREDNISOLONE; OXYMETHOLONE; PENICILLIN G; STREPTOMYCIN; THYMOCYTE ANTIBODY;

EID: 0036430336     PISSN: 14664860     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.thj.6200187     Document Type: Article
Times cited : (33)

References (31)
  • 2
    • 0025223735 scopus 로고
    • The hematopoietic defect in aplastic anemia assessed by long-term marrow culture
    • Marsh JC, Chang J, Testa NG, Hows JM, Dexter TM. The hematopoietic defect in aplastic anemia assessed by long-term marrow culture. Blood 1990; 76: 1748-1757.
    • (1990) Blood , vol.76 , pp. 1748-1757
    • Marsh, J.C.1    Chang, J.2    Testa, N.G.3    Hows, J.M.4    Dexter, T.M.5
  • 3
    • 0025880606 scopus 로고
    • In vitro assessment of marrow 'stem cell' and stromal cell function in aplastic anaemia
    • Marsh JC, Chang J, Testa NG, Hows JM, Dexter TM. In vitro assessment of marrow 'stem cell' and stromal cell function in aplastic anaemia. Br J Haematol 1991; 78: 258-267.
    • (1991) Br. J. Haematol , vol.78 , pp. 258-267
    • Marsh, J.C.1    Chang, J.2    Testa, N.G.3    Hows, J.M.4    Dexter, T.M.5
  • 4
    • 0024466796 scopus 로고
    • Characterization and partial purification of human marrow cells capable of initiating long-term hematopoiesis in vitro
    • Sutherland HJ, Eaves CJ, Eaves AC, Dragowska W, Lansdorp PM. Characterization and partial purification of human marrow cells capable of initiating long-term hematopoiesis in vitro. Blood 1989; 74: 1563-1570.
    • (1989) Blood , vol.74 , pp. 1563-1570
    • Sutherland, H.J.1    Eaves, C.J.2    Eaves, A.C.3    Dragowska, W.4    Lansdorp, P.M.5
  • 5
    • 0027217492 scopus 로고
    • A murine stromal cell line allows the proliferation of very primitive human CD34 + +/CD38- progenitor cells in long-term cultures and semisolid assays
    • Issaad C, Croisille L, Katz A, Vainchenker W, Coulombel L. A murine stromal cell line allows the proliferation of very primitive human CD34 + +/CD38- progenitor cells in long-term cultures and semisolid assays. Blood 1993; 81: 2916-2924.
    • (1993) Blood , vol.81 , pp. 2916-2924
    • Issaad, C.1    Croisille, L.2    Katz, A.3    Vainchenker, W.4    Coulombel, L.5
  • 6
    • 0025719690 scopus 로고
    • Use of limiting-dilution type long-term marrow cultures in frequency analysis of marrow-repopulating and spleen colony-forming hematopoietic stem cells in the mouse
    • Ploemacher RE, Van der Sluijs JP, van Beurden CA, Baert MR, Chan PL. Use of limiting-dilution type long-term marrow cultures in frequency analysis of marrow-repopulating and spleen colony-forming hematopoietic stem cells in the mouse. Blood 1991; 78: 2527-2533.
    • (1991) Blood , vol.78 , pp. 2527-2533
    • Ploemacher, R.E.1    Van der Sluijs, J.P.2    van Beurden, C.A.3    Baert, M.R.4    Chan, P.L.5
  • 7
    • 0029992672 scopus 로고    scopus 로고
    • Quantitative analysis of cobblestone area-forming cells in bone marrow of patients with aplastic anemia by limiting dilution assay
    • Schrezenmeier H, Jenal M, Herrmann F, Heimpel H, Raghavachar A. Quantitative analysis of cobblestone area-forming cells in bone marrow of patients with aplastic anemia by limiting dilution assay. Blood 1996; 88: 4474-4480.
    • (1996) Blood , vol.88 , pp. 4474-4480
    • Schrezenmeier, H.1    Jenal, M.2    Herrmann, F.3    Heimpel, H.4    Raghavachar, A.5
  • 8
    • 0024602797 scopus 로고
    • Precursors of colony-forming cells in humans can be distinguished from colony-forming cells by expression of the CD33 and CD34 antigens and light scatter properties
    • Andrews RG, Singer JW, Bernstein ID. Precursors of colony-forming cells in humans can be distinguished from colony-forming cells by expression of the CD33 and CD34 antigens and light scatter properties. J Exp Med 1989; 169: 1721-1731.
    • (1989) J. Exp. Med , vol.169 , pp. 1721-1731
    • Andrews, R.G.1    Singer, J.W.2    Bernstein, I.D.3
  • 9
    • 0029815702 scopus 로고    scopus 로고
    • A severe and consistent deficit in marrow and circulating primitive hematopoietic cells (long-term culture-initiating cells) in acquired aplastic anemia
    • Maciejewski JP, Selleri C, Sato T, Anderson S, Young NS. A severe and consistent deficit in marrow and circulating primitive hematopoietic cells (long-term culture-initiating cells) in acquired aplastic anemia. 1996; Blood 88: 1983-1991.
    • (1996) Blood , vol.88 , pp. 1983-1991
    • Maciejewski, J.P.1    Selleri, C.2    Sato, T.3    Anderson, S.4    Young, N.S.5
  • 10
    • 0031454553 scopus 로고    scopus 로고
    • Measurement of long-term culture initiating cells (LTC-ICs) using limiting dilution: Comparison of endpoints and stromal support
    • Weaver A, Ryder WD, Testa NG. Measurement of long-term culture initiating cells (LTC-ICs) using limiting dilution: comparison of endpoints and stromal support. Exp Hematol 1997; 25: 1333-1338.
    • (1997) Exp. Hematol , vol.25 , pp. 1333-1338
    • Weaver, A.1    Ryder, W.D.2    Testa, N.G.3
  • 11
    • 0032521422 scopus 로고    scopus 로고
    • The assessment of the hematopoietic reservoir after immunosuppressive therapy or bone marrow transplantation in severe aplastic anemia
    • Podesta M, Piaggio G, Frassoni F, Pitto A, Zikos P. The assessment of the hematopoietic reservoir after immunosuppressive therapy or bone marrow transplantation in severe aplastic anemia. Blood 1998; 91: 1959-1965.
    • (1998) Blood , vol.91 , pp. 1959-1965
    • Podesta, M.1    Piaggio, G.2    Frassoni, F.3    Pitto, A.4    Zikos, P.5
  • 12
    • 0032101591 scopus 로고    scopus 로고
    • Quantitative long-term culture-initiating cell assays require accessory cell depletion that can be achieved by CD34-enrichment or 5-fluorouracil exposure
    • Koller MR, Manchel I, Smith AK. Quantitative long-term culture-initiating cell assays require accessory cell depletion that can be achieved by CD34-enrichment or 5-fluorouracil exposure. Blood 1998; 91: 4056-4064.
    • (1998) Blood , vol.91 , pp. 4056-4064
    • Koller, M.R.1    Manchel, I.2    Smith, A.K.3
  • 13
    • 0029609759 scopus 로고
    • Increased apoptosis in aplastic anemia bone marrow progenitor cells: Possible pathophysiologic significance
    • Philpott NJ, Scopes J, Marsh JC, Gordon-Smith EC, Gibson FM. Increased apoptosis in aplastic anemia bone marrow progenitor cells: possible pathophysiologic significance. Exp Hematol 1995; 23: 1642-1648.
    • (1995) Exp. Hematol , vol.23 , pp. 1642-1648
    • Philpott, N.J.1    Scopes, J.2    Marsh, J.C.3    Gordon-Smith, E.C.4    Gibson, F.M.5
  • 14
    • 0033950194 scopus 로고    scopus 로고
    • Hematopoietic cell destruction by immune mechanisms in acquired aplastic anemia
    • Young NS. Hematopoietic cell destruction by immune mechanisms in acquired aplastic anemia. Sem Hematol 2000; 37: 3-14.
    • (2000) Sem. Hematol , vol.37 , pp. 3-14
    • Young, N.S.1
  • 15
    • 0016671332 scopus 로고
    • Selection of patients for bone marrow transplantation in severe aplastic anemia
    • Camitta BM, Rappeport JM, Parkman R, Nathan DG. Selection of patients for bone marrow transplantation in severe aplastic anemia. Blood 1975; 45: 355-363.
    • (1975) Blood , vol.45 , pp. 355-363
    • Camitta, B.M.1    Rappeport, J.M.2    Parkman, R.3    Nathan, D.G.4
  • 16
    • 0023794546 scopus 로고
    • Bone marrow transplantation (BMT) versus immunosuppression for the treatment of severe aplastic anaemia (SAA): A report of the EBMT SAA working party
    • Bacigalupo A, Hows J, Gluckman E, Nissen C, Marsh JC, Van Lint MT et al. Bone marrow transplantation (BMT) versus immunosuppression for the treatment of severe aplastic anaemia (SAA): a report of the EBMT SAA working party. Br J Haematol 1988; 70: 177-182.
    • (1988) Br. J. Haematol , vol.70 , pp. 177-182
    • Bacigalupo, A.1    Hows, J.2    Gluckman, E.3    Nissen, C.4    Marsh, J.C.5    Van Lint, M.T.6
  • 17
    • 0024562238 scopus 로고
    • Reproducible establishment of hemopoietic supportive stromal cell lines from murine bone marrow
    • Itoh K, Tezuka H, Sakoda H, Konno M, Nagata K, Uchiyama T et al. Reproducible establishment of hemopoietic supportive stromal cell lines from murine bone marrow. Exp Hematol 1989; 17: 145-153.
    • (1989) Exp. Hematol , vol.17 , pp. 145-153
    • Itoh, K.1    Tezuka, H.2    Sakoda, H.3    Konno, M.4    Nagata, K.5    Uchiyama, T.6
  • 18
    • 0019468220 scopus 로고
    • Limiting dilution assays for the determination of immunocompetent cell frequencies. I. Data analysis
    • Taswell C. Limiting dilution assays for the determination of immunocompetent cell frequencies. I. Data analysis. J Immunol 1981; 126: 1614-1619.
    • (1981) J. Immunol , vol.126 , pp. 1614-1619
    • Taswell, C.1
  • 19
    • 0020067009 scopus 로고
    • The evaluation of limiting dilution assays
    • Fazekas de St.Groth S. The evaluation of limiting dilution assays. J Immunol Methods 1982; 49: R11-R23.
    • (1982) J. Immunol. Methods , vol.49
    • Fazekas de St.Groth, S.1
  • 20
    • 0029048258 scopus 로고
    • Increased expression of Fas antigen on bone marrow CD34+ cells of patients with aplastic anaemia
    • Maciejewski JP, Selleri C, Sato T, Anderson S, Young NS. Increased expression of Fas antigen on bone marrow CD34+ cells of patients with aplastic anaemia. Br J Haematol 1995; 91: 245-252.
    • (1995) Br. J. Haematol , vol.91 , pp. 245-252
    • Maciejewski, J.P.1    Selleri, C.2    Sato, T.3    Anderson, S.4    Young, N.S.5
  • 21
    • 0025297090 scopus 로고
    • Functional characterization of individual human hematopoietic stem cells cultured at limiting dilution on supportive marrow stromal layers
    • Sutherland HJ, Lansdorp PM, Henkelman DH, Eaves AC, Eaves CJ. Functional characterization of individual human hematopoietic stem cells cultured at limiting dilution on supportive marrow stromal layers. Proc Nat Acad Sci USA 1990; 87: 3584-3588.
    • (1990) Proc. Nat. Acad. Sci. USA , vol.87 , pp. 3584-3588
    • Sutherland, H.J.1    Lansdorp, P.M.2    Henkelman, D.H.3    Eaves, A.C.4    Eaves, C.J.5
  • 22
    • 0028277465 scopus 로고
    • Phenotypic and functional analysis of bone marrow progenitor cell compartment in bone marrow failure
    • Maciejewski JP, Anderson S, Katevas P, Young NS. Phenotypic and functional analysis of bone marrow progenitor cell compartment in bone marrow failure. Br J Haematol 1994; 87: 227-234.
    • (1994) Br. J. Haematol , vol.87 , pp. 227-234
    • Maciejewski, J.P.1    Anderson, S.2    Katevas, P.3    Young, N.S.4
  • 23
    • 0029782323 scopus 로고    scopus 로고
    • Deficiency of CD34+ c-kit+ and CD34+38- hematopoietic precursors in aplastic anemia after immunosuppressive treatment
    • Manz CY, Nissen C, Wodnar-Filipowicz A. Deficiency of CD34+ c-kit+ and CD34+38- hematopoietic precursors in aplastic anemia after immunosuppressive treatment. Am J Hematol 1996; 52: 264-274.
    • (1996) Am. J. Hematol , vol.52 , pp. 264-274
    • Manz, C.Y.1    Nissen, C.2    Wodnar-Filipowicz, A.3
  • 24
    • 0033566322 scopus 로고    scopus 로고
    • Murine stromal cells counteract the loss of long-term culture-initiating cell potential induced by cytokines in CD34(+)CD38(low/neg) human bone marrow cells
    • Bennaceur-Griscelli A, Tourino C, Izac B, Vainchenker W, Coulombel L. Murine stromal cells counteract the loss of long-term culture-initiating cell potential induced by cytokines in CD34(+)CD38(low/neg) human bone marrow cells. Blood 1999; 94: 529-538.
    • (1999) Blood , vol.94 , pp. 529-538
    • Bennaceur-Griscelli, A.1    Tourino, C.2    Izac, B.3    Vainchenker, W.4    Coulombel, L.5
  • 25
    • 0032958975 scopus 로고    scopus 로고
    • Direct contact between CD34 + lin- cells and stroma induces a soluble activity that specifically increases primitive hematopoietic cell production
    • Koller MR, Oxender M, Jensen TC, Goltry KL, Smith AK. Direct contact between CD34 + lin- cells and stroma induces a soluble activity that specifically increases primitive hematopoietic cell production. Exp Hematol 1999; 27: 734-741.
    • (1999) Exp. Hematol , vol.27 , pp. 734-741
    • Koller, M.R.1    Oxender, M.2    Jensen, T.C.3    Goltry, K.L.4    Smith, A.K.5
  • 26
    • 0011484026 scopus 로고    scopus 로고
    • Cytokine abnormalities in aplastic anemia
    • (ed) Schrezenmeier H, Bacigalupo A (eds.) Cambridge University Press, Cambridge
    • Kojima S. (ed) Cytokine abnormalities in aplastic anemia, In: Schrezenmeier H, Bacigalupo A (eds.) Aplastic Anemia. Cambridge University Press, Cambridge, 2000; pp 21-40.
    • (2000) Aplastic Anemia , pp. 21-40
    • Kojima, S.1
  • 29
    • 0028966584 scopus 로고
    • Functional isolation and characterization of human hematopoietic stem cells
    • Berardi AC, Wang A, Levine JD, Lopez P, Scadden DT. Functional isolation and characterization of human hematopoietic stem cells. Science 1995; 267: 104-108.
    • (1995) Science , vol.267 , pp. 104-108
    • Berardi, A.C.1    Wang, A.2    Levine, J.D.3    Lopez, P.4    Scadden, D.T.5
  • 30
    • 0034487601 scopus 로고    scopus 로고
    • Mechanisms of bone marrow progenitor cell apoptosis in aplastic anaemia and the effect of antithymocyte globulin: Examination of the role of the Fas-Fas-L interaction
    • Killick SB, Cox CV, Marsh JCW, Gordon-Smith EC, Gibson FM. Mechanisms of bone marrow progenitor cell apoptosis in aplastic anaemia and the effect of antithymocyte globulin: examination of the role of the Fas-Fas-L interaction. Br J Haematol 2000; 111: 1164-1169.
    • (2000) Br. J. Haematol , vol.111 , pp. 1164-1169
    • Killick, S.B.1    Cox, C.V.2    Marsh, J.C.W.3    Gordon-Smith, E.C.4    Gibson, F.M.5
  • 31
    • 0011394940 scopus 로고    scopus 로고
    • Immunosuppressive Treatment of Aplastic Anemia
    • (ed) Schrezenmeier H, Bacigalupo A (eds.) Cambridge University Press, Cambridge
    • Tichelli A, Schrezenmeier H, Bacigalupo A. (ed) Immunosuppressive Treatment of Aplastic Anemia, In: Schrezenmeier H, Bacigalupo A (eds.) Aplastic Anemia. Cambridge University Press, Cambridge, 2000; pp 154-196.
    • (2000) Aplastic Anemia , pp. 154-196
    • Tichelli, A.1    Schrezenmeier, H.2    Bacigalupo, A.3


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