Label-free biosensor assays in GPCR screening

Methods in Molecular Biology

Volumn 1272, Issue , 2015, Pages 199-213

  Grundmann, Manuel ^a   Kostenis, Evi ^a  

^a NONE

Author keywords

DMR; Dynamic mass redistribution; FFA1; G proteincoupled receptor; Holistic readout; Integrated cell response; Label free; Ligand bias; Optical biosensor; Real time assay; Resonant waveguide grating; RWG

Indexed keywords

G PROTEIN COUPLED RECEPTOR; G PROTEIN COUPLED RECEPTOR 40; CONJUGATED LINOLEIC ACID; FFAR1 PROTEIN, HUMAN; LIGAND; MOLECULAR LIBRARY; RECOMBINANT PROTEIN;

ARTICLE; BIOSENSOR; CELL COUNT; CELL DIFFERENTIATION; CELL FUNCTION; CELL GROWTH; CELL MOTION; CONTROLLED STUDY; EMBRYO; EXTRACELLULAR MATRIX; HEK293 CELL LINE; HUMAN; HUMAN CELL; IC50; IN VITRO STUDY; OPTICAL DENSITY; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN ANALYSIS; SECOND MESSENGER ASSAY; AGONISTS; CHEMISTRY; GENE EXPRESSION; GENETIC PROCEDURES; GENETICS; HIGH THROUGHPUT SCREENING; METABOLISM; MOLECULAR LIBRARY; OPTICAL INSTRUMENTATION; PHARMACOLOGY; PLASMID; STATISTICAL DISTRIBUTION;

BIOSENSING TECHNIQUES; GENE EXPRESSION; HEK293 CELLS; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; LIGANDS; LINOLEIC ACIDS, CONJUGATED; OPTICAL DEVICES; PLASMIDS; RECEPTORS, G-PROTEIN-COUPLED; RECOMBINANT PROTEINS; SMALL MOLECULE LIBRARIES; STATISTICAL DISTRIBUTIONS;

EID: 84954574088     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4939-2336-6_14     Document Type: Article

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