Activation of aryl hydrocarbon receptor mediates suppression of hypoxia-inducible factor-dependent erythropoietin expression by indoxyl sulfate

American Journal of Physiology - Cell Physiology

Volumn 310, Issue 2, 2016, Pages C142-C150

  Asai, Hirobumi ^a   Hirata, Junya ^a   Hirano, Ayumi ^a   Hirai, Kazuya ^a   Seki, Sayaka ^a   Watanabe Akanuma, Mie ^a  

^a KUREHA CORPORATION   (Japan)

Author keywords

Aryl hydrocarbon receptor; Erythropoietin; Hypoxia inducible factor; Indoxyl sulfate; Renal anemia

Indexed keywords

AROMATIC HYDROCARBON RECEPTOR; COBALT CHLORIDE; ERYTHROPOIETIN; HYPOXIA INDUCIBLE FACTOR; INDICAN; EPO PROTEIN, HUMAN; HYPOXIA INDUCIBLE FACTOR 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLEEDING; CELL HYPOXIA; CHRONIC KIDNEY DISEASE; COMPLEX FORMATION; CONTROLLED STUDY; ERYTHROPOIESIS; HUMAN; HUMAN CELL; KIDNEY DYSFUNCTION; LIVER; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RENAL ANEMIA; RENAL CORTICAL TISSUE; TRANSCRIPTION INITIATION; ANIMAL; DOSE RESPONSE; DOWN REGULATION; DRUG EFFECTS; HEPG2 CELL LINE; METABOLISM; PHYSIOLOGY; SPRAGUE DAWLEY RAT;

ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; ERYTHROPOIETIN; HEP G2 CELLS; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1; INDICAN; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, ARYL HYDROCARBON;

EID: 84954543053     PISSN: 03636143     EISSN: 15221563     Source Type: Journal    
DOI: 10.1152/ajpcell.00172.2015     Document Type: Article

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