-
1
-
-
84957353129
-
The participation of inorganic pyrophosphate in the reversible enzymatic synthesis of diphosphopyridine nucleotide
-
Kornberg A, (1948) The participation of inorganic pyrophosphate in the reversible enzymatic synthesis of diphosphopyridine nucleotide. J Biol Chem 176: 1475-1476.
-
(1948)
J Biol Chem
, vol.176
, pp. 1475-1476
-
-
Kornberg, A.1
-
2
-
-
79960605733
-
Reducing expression of NAD+ synthesizing enzyme NMNAT1 does not affect the rate of Wallerian degeneration
-
Conforti L, Janeckova L, Wagner D, Mazzola F, Cialabrini L, et al. (2011) Reducing expression of NAD+ synthesizing enzyme NMNAT1 does not affect the rate of Wallerian degeneration. FEBS J 278: 2666-2679.
-
(2011)
FEBS J
, vol.278
, pp. 2666-2679
-
-
Conforti, L.1
Janeckova, L.2
Wagner, D.3
Mazzola, F.4
Cialabrini, L.5
-
3
-
-
0020505149
-
An indispensable gene for NAD biosynthesis in Salmonella typhimurium
-
Hughes KT, Ladika D, Roth JR, Olivera BM, (1983) An indispensable gene for NAD biosynthesis in Salmonella typhimurium. J Bacteriol 155: 213-221.
-
(1983)
J Bacteriol
, vol.155
, pp. 213-221
-
-
Hughes, K.T.1
Ladika, D.2
Roth, J.R.3
Olivera, B.M.4
-
4
-
-
69949111619
-
From heterochromatin islands to the NAD World: a hierarchical view of aging through the functions of mammalian Sirt1 and systemic NAD biosynthesis
-
Imai S, (2009) From heterochromatin islands to the NAD World: a hierarchical view of aging through the functions of mammalian Sirt1 and systemic NAD biosynthesis. Biochim Biophys Acta 1790: 997-1004.
-
(2009)
Biochim Biophys Acta
, vol.1790
, pp. 997-1004
-
-
Imai, S.1
-
5
-
-
33745817828
-
Molecular basis for the inhibition of human NMPRTase, a novel target for anticancer agents
-
Khan JA, Tao X, Tong L, (2006) Molecular basis for the inhibition of human NMPRTase, a novel target for anticancer agents. Nat Struct Mol Biol 13: 582-588.
-
(2006)
Nat Struct Mol Biol
, vol.13
, pp. 582-588
-
-
Khan, J.A.1
Tao, X.2
Tong, L.3
-
6
-
-
0242526050
-
FK866, a highly specific noncompetitive inhibitor of nicotinamide phosphoribosyltransferase, represents a novel mechanism for induction of tumor cell apoptosis
-
Hasmann M, Schemainda I, (2003) FK866, a highly specific noncompetitive inhibitor of nicotinamide phosphoribosyltransferase, represents a novel mechanism for induction of tumor cell apoptosis. Cancer Res 63: 7436-7442.
-
(2003)
Cancer Res
, vol.63
, pp. 7436-7442
-
-
Hasmann, M.1
Schemainda, I.2
-
7
-
-
68949210360
-
Nicotinamide/nicotinic acid mononucleotide adenylyltransferase, new insights into an ancient enzyme
-
Zhai RG, Rizzi M, Garavaglia S, (2009) Nicotinamide/nicotinic acid mononucleotide adenylyltransferase, new insights into an ancient enzyme. Cell Mol Life Sci 66: 2805-2818.
-
(2009)
Cell Mol Life Sci
, vol.66
, pp. 2805-2818
-
-
Zhai, R.G.1
Rizzi, M.2
Garavaglia, S.3
-
8
-
-
65649151404
-
NAD(P) biosynthesis enzymes as potential targets for selective drug design
-
Magni G, Di Stefano M, Orsomando G, Raffaelli N, Ruggieri S, (2009) NAD(P) biosynthesis enzymes as potential targets for selective drug design. Curr Med Chem 16: 1372-1390.
-
(2009)
Curr Med Chem
, vol.16
, pp. 1372-1390
-
-
Magni, G.1
Di Stefano, M.2
Orsomando, G.3
Raffaelli, N.4
Ruggieri, S.5
-
9
-
-
63849199824
-
The NMN/NaMN adenylyltransferase (NMNAT) protein family
-
Lau C, Niere M, Ziegler M, (2009) The NMN/NaMN adenylyltransferase (NMNAT) protein family. Front Biosci 14: 410-431.
-
(2009)
Front Biosci
, vol.14
, pp. 410-431
-
-
Lau, C.1
Niere, M.2
Ziegler, M.3
-
10
-
-
1842534935
-
Structure and function of nicotinamide mononucleotide adenylyltransferase
-
Magni G, Amici A, Emanuelli M, Orsomando G, Raffaelli N, et al. (2004) Structure and function of nicotinamide mononucleotide adenylyltransferase. Curr Med Chem 11: 873-885.
-
(2004)
Curr Med Chem
, vol.11
, pp. 873-885
-
-
Magni, G.1
Amici, A.2
Emanuelli, M.3
Orsomando, G.4
Raffaelli, N.5
-
11
-
-
79957543031
-
Compartmentation of NAD+-dependent signalling
-
Koch-Nolte F, Fischer S, Haag F, Ziegler M, (2011) Compartmentation of NAD+-dependent signalling. FEBS Lett 585: 1651-1656.
-
(2011)
FEBS Lett
, vol.585
, pp. 1651-1656
-
-
Koch-Nolte, F.1
Fischer, S.2
Haag, F.3
Ziegler, M.4
-
13
-
-
34247500849
-
Initial-rate kinetics of human NMN-adenylyltransferases: substrate and metal ion specificity, inhibition by products and multisubstrate analogues, and isozyme contributions to NAD+ biosynthesis
-
Sorci L, Cimadamore F, Scotti S, Petrelli R, Cappellacci L, et al. (2007) Initial-rate kinetics of human NMN-adenylyltransferases: substrate and metal ion specificity, inhibition by products and multisubstrate analogues, and isozyme contributions to NAD+ biosynthesis. Biochemistry 46: 4912-4922.
-
(2007)
Biochemistry
, vol.46
, pp. 4912-4922
-
-
Sorci, L.1
Cimadamore, F.2
Scotti, S.3
Petrelli, R.4
Cappellacci, L.5
-
14
-
-
27744501798
-
Subcellular compartmentation and differential catalytic properties of the three human nicotinamide mononucleotide adenylyltransferase isoforms
-
Berger F, Lau C, Dahlmann M, Ziegler M, (2005) Subcellular compartmentation and differential catalytic properties of the three human nicotinamide mononucleotide adenylyltransferase isoforms. J Biol Chem 280: 36334-36341.
-
(2005)
J Biol Chem
, vol.280
, pp. 36334-36341
-
-
Berger, F.1
Lau, C.2
Dahlmann, M.3
Ziegler, M.4
-
15
-
-
0037040970
-
Structure of human NMN adenylyltransferase. A key nuclear enzyme for NAD homeostasis
-
Garavaglia S, D'Angelo I, Emanuelli M, Carnevali F, Pierella F, et al. (2002) Structure of human NMN adenylyltransferase. A key nuclear enzyme for NAD homeostasis. J Biol Chem 277: 8524-8530.
-
(2002)
J Biol Chem
, vol.277
, pp. 8524-8530
-
-
Garavaglia, S.1
D'Angelo, I.2
Emanuelli, M.3
Carnevali, F.4
Pierella, F.5
-
16
-
-
78649637700
-
Homology modeling and deletion mutants of human nicotinamide mononucleotide adenylyltransferase isozyme 2: new insights on structure and function relationship
-
Brunetti L, Di Stefano M, Ruggieri S, Cimadamore F, Magni G, (2010) Homology modeling and deletion mutants of human nicotinamide mononucleotide adenylyltransferase isozyme 2: new insights on structure and function relationship. Protein Sci 19: 2440-2450.
-
(2010)
Protein Sci
, vol.19
, pp. 2440-2450
-
-
Brunetti, L.1
Di Stefano, M.2
Ruggieri, S.3
Cimadamore, F.4
Magni, G.5
-
17
-
-
0036031865
-
Identification of a novel human nicotinamide mononucleotide adenylyltransferase
-
Raffaelli N, Sorci L, Amici A, Emanuelli M, Mazzola F, et al. (2002) Identification of a novel human nicotinamide mononucleotide adenylyltransferase. Biochem Biophys Res Commun 297: 835-840.
-
(2002)
Biochem Biophys Res Commun
, vol.297
, pp. 835-840
-
-
Raffaelli, N.1
Sorci, L.2
Amici, A.3
Emanuelli, M.4
Mazzola, F.5
-
18
-
-
77953314024
-
Isoform-specific targeting and interaction domains in human nicotinamide mononucleotide adenylyltransferases
-
Lau C, Dolle C, Gossmann TI, Agledal L, Niere M, et al. (2010) Isoform-specific targeting and interaction domains in human nicotinamide mononucleotide adenylyltransferases. J Biol Chem 285: 18868-18876.
-
(2010)
J Biol Chem
, vol.285
, pp. 18868-18876
-
-
Lau, C.1
Dolle, C.2
Gossmann, T.I.3
Agledal, L.4
Niere, M.5
-
19
-
-
0038644836
-
Structural characterization of a human cytosolic NMN/NaMN adenylyltransferase and implication in human NAD biosynthesis
-
Zhang X, Kurnasov OV, Karthikeyan S, Grishin NV, Osterman AL, et al. (2003) Structural characterization of a human cytosolic NMN/NaMN adenylyltransferase and implication in human NAD biosynthesis. J Biol Chem 278: 13503-13511.
-
(2003)
J Biol Chem
, vol.278
, pp. 13503-13511
-
-
Zhang, X.1
Kurnasov, O.V.2
Karthikeyan, S.3
Grishin, N.V.4
Osterman, A.L.5
-
20
-
-
77953139085
-
Unique expression pattern of human nicotinamide mononucleotide adenylyltransferase isozymes in red blood cells
-
Di Stefano M, Galassi L, Magni G, (2010) Unique expression pattern of human nicotinamide mononucleotide adenylyltransferase isozymes in red blood cells. Blood Cells Mol Dis 45: 33-39.
-
(2010)
Blood Cells Mol Dis
, vol.45
, pp. 33-39
-
-
Di Stefano, M.1
Galassi, L.2
Magni, G.3
-
21
-
-
42049105745
-
Nicotinamide adenine dinucleotide based therapeutics
-
Chen L, Petrelli R, Felczak K, Gao G, Bonnac L, et al. (2008) Nicotinamide adenine dinucleotide based therapeutics. Curr Med Chem 15: 650-670.
-
(2008)
Curr Med Chem
, vol.15
, pp. 650-670
-
-
Chen, L.1
Petrelli, R.2
Felczak, K.3
Gao, G.4
Bonnac, L.5
-
22
-
-
79957549799
-
Pathways and subcellular compartmentation of NAD biosynthesis in human cells: from entry of extracellular precursors to mitochondrial NAD generation
-
Nikiforov A, Dolle C, Niere M, Ziegler M, (2011) Pathways and subcellular compartmentation of NAD biosynthesis in human cells: from entry of extracellular precursors to mitochondrial NAD generation. J Biol Chem 286: 21767-21778.
-
(2011)
J Biol Chem
, vol.286
, pp. 21767-21778
-
-
Nikiforov, A.1
Dolle, C.2
Niere, M.3
Ziegler, M.4
-
23
-
-
78650071674
-
Expression, localization, and biochemical characterization of nicotinamide mononucleotide adenylyltransferase 2
-
Mayer PR, Huang N, Dewey CM, Dries DR, Zhang H, et al. (2010) Expression, localization, and biochemical characterization of nicotinamide mononucleotide adenylyltransferase 2. J Biol Chem 285: 40387-40396.
-
(2010)
J Biol Chem
, vol.285
, pp. 40387-40396
-
-
Mayer, P.R.1
Huang, N.2
Dewey, C.M.3
Dries, D.R.4
Zhang, H.5
-
24
-
-
34247278118
-
Regulation of poly(ADP-ribose) polymerase 1 activity by the phosphorylation state of the nuclear NAD biosynthetic enzyme NMN adenylyl transferase 1
-
Berger F, Lau C, Ziegler M, (2007) Regulation of poly(ADP-ribose) polymerase 1 activity by the phosphorylation state of the nuclear NAD biosynthetic enzyme NMN adenylyl transferase 1. Proc Natl Acad Sci U S A 104: 3765-3770.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 3765-3770
-
-
Berger, F.1
Lau, C.2
Ziegler, M.3
-
25
-
-
52049117617
-
Enzymology of mammalian NAD metabolism in health and disease
-
Magni G, Orsomando G, Raffelli N, Ruggieri S, (2008) Enzymology of mammalian NAD metabolism in health and disease. Front Biosci 13: 6135-6154.
-
(2008)
Front Biosci
, vol.13
, pp. 6135-6154
-
-
Magni, G.1
Orsomando, G.2
Raffelli, N.3
Ruggieri, S.4
-
27
-
-
78649419017
-
Wld(S), NMNATs and axon degeneration-progress in the past two decades
-
Feng Y, Yan T, He Z, Zhai Q, (2010) Wld(S), NMNATs and axon degeneration-progress in the past two decades. Protein Cell 1: 237-245.
-
(2010)
Protein Cell
, vol.1
, pp. 237-245
-
-
Feng, Y.1
Yan, T.2
He, Z.3
Zhai, Q.4
-
28
-
-
77957001346
-
Wallerian degeneration, Wld(S), and NMNAT
-
Coleman MP, Freeman MR, (2010) Wallerian degeneration, Wld(S), and NMNAT. Annu Rev Neurosci 33: 245-267.
-
(2010)
Annu Rev Neurosci
, vol.33
, pp. 245-267
-
-
Coleman, M.P.1
Freeman, M.R.2
-
29
-
-
67049160318
-
NAD and axon degeneration: from the Wlds gene to neurochemistry
-
Wang J, He Z, (2009) NAD and axon degeneration: from the Wlds gene to neurochemistry. Cell Adh Migr 3: 77-87.
-
(2009)
Cell Adh Migr
, vol.3
, pp. 77-87
-
-
Wang, J.1
He, Z.2
-
30
-
-
65649126738
-
Nicotinamide mononucleotide adenylyl transferase-mediated axonal protection requires enzymatic activity but not increased levels of neuronal nicotinamide adenine dinucleotide
-
Sasaki Y, Vohra BP, Lund FE, Milbrandt J, (2009) Nicotinamide mononucleotide adenylyl transferase-mediated axonal protection requires enzymatic activity but not increased levels of neuronal nicotinamide adenine dinucleotide. J Neurosci 29: 5525-5535.
-
(2009)
J Neurosci
, vol.29
, pp. 5525-5535
-
-
Sasaki, Y.1
Vohra, B.P.2
Lund, F.E.3
Milbrandt, J.4
-
31
-
-
0037012844
-
Axonal self-destruction and neurodegeneration
-
Raff MC, Whitmore AV, Finn JT, (2002) Axonal self-destruction and neurodegeneration. Science 296: 868-871.
-
(2002)
Science
, vol.296
, pp. 868-871
-
-
Raff, M.C.1
Whitmore, A.V.2
Finn, J.T.3
-
32
-
-
0024373441
-
Absence of Wallerian degeneration does not hinder regeneration in peripheral nerve
-
Lunn ER, Perry VH, Brown MC, Rosen H, Gordon S, (1989) Absence of Wallerian degeneration does not hinder regeneration in peripheral nerve. Eur J Neurosci 1: 27-33.
-
(1989)
Eur J Neurosci
, vol.1
, pp. 27-33
-
-
Lunn, E.R.1
Perry, V.H.2
Brown, M.C.3
Rosen, H.4
Gordon, S.5
-
33
-
-
20444372657
-
Neuroprotective strategies in MS: lessons from C57BL/Wld(S) mice
-
Coleman MP, Adalbert R, Beirowski B, (2005) Neuroprotective strategies in MS: lessons from C57BL/Wld(S) mice. J Neurol Sci 233: 133-138.
-
(2005)
J Neurol Sci
, vol.233
, pp. 133-138
-
-
Coleman, M.P.1
Adalbert, R.2
Beirowski, B.3
-
35
-
-
23744474976
-
A local mechanism mediates NAD-dependent protection of axon degeneration
-
Wang J, Zhai Q, Chen Y, Lin E, Gu W, et al. (2005) A local mechanism mediates NAD-dependent protection of axon degeneration. J Cell Biol 170: 349-355.
-
(2005)
J Cell Biol
, vol.170
, pp. 349-355
-
-
Wang, J.1
Zhai, Q.2
Chen, Y.3
Lin, E.4
Gu, W.5
-
36
-
-
77954617977
-
Endogenous NMNAT2 is an essential survival factor for maintenance of healthy axons
-
Gilley J, Coleman MP, (2010) Endogenous NMNAT2 is an essential survival factor for maintenance of healthy axons. PLoS Biol 8: e1000300.
-
(2010)
PLoS Biol
, vol.8
-
-
Gilley, J.1
Coleman, M.P.2
-
37
-
-
0029012892
-
Assay methods for nicotinamide mononucleotide adenylyltransferase of wide applicability
-
Balducci E, Emanuelli M, Raffaelli N, Ruggieri S, Amici A, et al. (1995) Assay methods for nicotinamide mononucleotide adenylyltransferase of wide applicability. Anal Biochem 228: 64-68.
-
(1995)
Anal Biochem
, vol.228
, pp. 64-68
-
-
Balducci, E.1
Emanuelli, M.2
Raffaelli, N.3
Ruggieri, S.4
Amici, A.5
-
39
-
-
0036581160
-
Relative expression software tool (REST) for group-wise comparison and statistical analysis of relative expression results in real-time PCR
-
Pfaffl MW, Horgan GW, Dempfle L, (2002) Relative expression software tool (REST) for group-wise comparison and statistical analysis of relative expression results in real-time PCR. Nucleic Acids Res 30: e36.
-
(2002)
Nucleic Acids Res
, vol.30
-
-
Pfaffl, M.W.1
Horgan, G.W.2
Dempfle, L.3
-
40
-
-
0035195636
-
Wallerian degeneration of injured axons and synapses is delayed by a Ube4b/NMNAT chimeric gene
-
Mack TG, Reiner M, Beirowski B, Mi W, Emanuelli M, et al. (2001) Wallerian degeneration of injured axons and synapses is delayed by a Ube4b/NMNAT chimeric gene. Nat Neurosci 4: 1199-1206.
-
(2001)
Nat Neurosci
, vol.4
, pp. 1199-1206
-
-
Mack, T.G.1
Reiner, M.2
Beirowski, B.3
Mi, W.4
Emanuelli, M.5
-
41
-
-
0034633627
-
A Ufd2/D4Cole1e chimeric protein and overexpression of Rbp7 in the slow Wallerian degeneration (WldS) mouse
-
Conforti L, Tarlton A, Mack TG, Mi W, Buckmaster EA, et al. (2000) A Ufd2/D4Cole1e chimeric protein and overexpression of Rbp7 in the slow Wallerian degeneration (WldS) mouse. Proc Natl Acad Sci U S A 97: 11377-11382.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 11377-11382
-
-
Conforti, L.1
Tarlton, A.2
Mack, T.G.3
Mi, W.4
Buckmaster, E.A.5
-
42
-
-
80755161488
-
Cloning, expression and characterization of mouse (Mus musculus) nicotinamide 5′-mononucleotide adenylyltransferase-2
-
Raches DW, Xiao S, Kusumanchi P, Yalowitz J, Sanghani P, et al. (2011) Cloning, expression and characterization of mouse (Mus musculus) nicotinamide 5′-mononucleotide adenylyltransferase-2. Med Chem 7: 718-726.
-
(2011)
Med Chem
, vol.7
, pp. 718-726
-
-
Raches, D.W.1
Xiao, S.2
Kusumanchi, P.3
Yalowitz, J.4
Sanghani, P.5
-
43
-
-
66049102890
-
Nicotinamide mononucleotide adenylyltransferase expression in mitochondrial matrix delays Wallerian degeneration
-
Yahata N, Yuasa S, Araki T, (2009) Nicotinamide mononucleotide adenylyltransferase expression in mitochondrial matrix delays Wallerian degeneration. J Neurosci 29: 6276-6284.
-
(2009)
J Neurosci
, vol.29
, pp. 6276-6284
-
-
Yahata, N.1
Yuasa, S.2
Araki, T.3
-
44
-
-
58849126602
-
Non-nuclear Wld(S) determines its neuroprotective efficacy for axons and synapses in vivo
-
Beirowski B, Babetto E, Gilley J, Mazzola F, Conforti L, et al. (2009) Non-nuclear Wld(S) determines its neuroprotective efficacy for axons and synapses in vivo. J Neurosci 29: 653-668.
-
(2009)
J Neurosci
, vol.29
, pp. 653-668
-
-
Beirowski, B.1
Babetto, E.2
Gilley, J.3
Mazzola, F.4
Conforti, L.5
|